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A Historical Perspective on Evidence Based Immunology

A Historical Perspective on Evidence Based Immunology Author Edward J. Moticka
ISBN-10 9780123983756
Release 2015-11-25
Pages 394
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A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology Presents concepts such as the division of lymphocytes into functionally different populations in their historical context Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells



Bionanotechnology

Bionanotechnology Author Anil Kumar Anal
ISBN-10 9781351643634
Release 2018-02-02
Pages 189
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This book deals with a subject of high interest and importance in all sectors, including biomedical, food, agriculture, energy, and environment. Biological systems are essential in nanotechnology, and many new applications are being developed by mimicking the natural systems. Approaching these topics from an engineering perspective, the book offers insight on the details of nanoscale fabrication processes as well as cell biology. The basics of biology and chemistry, with a focus on how to engineer the behavior of molecules at the nanoscale, are also explored and analyzed. The aim of the text is to provide the reader with broader knowledge of biological methods for signal transduction and molecular recognitions systems and how they can be replicated in bio-sensing applications. The reader will learn the basic structures and interactions of biomacromolecules for developing biocompatible and eco-friendly devices.



Life Cycle Nutrition An Evidence Based Approach

Life Cycle Nutrition  An Evidence Based Approach Author Sari Edelstein
ISBN-10 9781449632236
Release 2010-12-30
Pages 532
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Life Cycle Nutrition: An Evidence-Based Approach uses the latest evidence-based research to explore the nutritional foundations and the growth, development and normal functioning of individuals through each stage of life. It covers the physiological, biochemical, sociological, and developmental factors that affect nutrient requirements and recommendations at various stages of the life cycle.



Bacteriophage Applications Historical Perspective and Future Potential

Bacteriophage Applications   Historical Perspective and Future Potential Author Jessica Nicastro
ISBN-10 9783319457918
Release 2016-10-04
Pages 82
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This book explores key applications of phage biotechnology and reviews recent advances in phage display technologies. The applications covered were selected on the basis of their significance and representativeness in the field. The small size and enormous diversity of bacteriophages make them ideal candidates for numerous applications across many industries. Since the discovery of phages and the advent of phage display systems, considerable attention has been focused on the development of novel therapeutic and industrial applications. Recent studies combine the genomic flexibility of phages with phage display systems in order to generate modified phages for targeted delivery.



Pharmaceutical Systems

Pharmaceutical Systems Author John Lilja
ISBN-10 9780470754047
Release 2008-05-27
Pages 356
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* Offers a social view of the activities leading to the timely patient access to medicines including: drug research, drug production, drug distribution, drug prescribing, drug information and drug control * Provides theoretical models to enable pharmacists to understand the organization of drug systems in their particular global territory * Written specifically with the needs of pharmacy students taking Master's degrees in mind



The Vaccine Book

The Vaccine Book Author Barry R. Bloom
ISBN-10 9780128054000
Release 2016-06-23
Pages 664
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The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy



Allergy and Asthma Practical Diagnosis and Management

Allergy and Asthma  Practical Diagnosis and Management Author Massoud Mahmoudi
ISBN-10 0071593535
Release 2007-10-09
Pages 400
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Clear, authoritative guidance for your day-to-day allergy and asthma practice Allergy and Asthma: Practical Diagnosis and Management is a concise guide that puts the most salient insights in allergy medicine right at your fingertips. Written by a leading allergy clinician, along with 30 nationally recognized expert contributors, this resource is perfect for front-line general practitioners, especially primary care physicians and allied health care providers. Inside, you'll find the most clinically relevant information on the pathophysiology, diagnosis, treatment, and prevention of all major allergic disorders. Features Need-to-know coverage that spans the entire scope of adult allergy and asthma-geared for real world medical practice A timely look at occupational allergies and allergies linked to unhealthy environments Organization by specific organ, which guides you to diagnostic and therapeutic solutions quickly and easily Essential chapters on the principles of diagnosis and on medications used in the management of simple and complex allergy Coverage of new complementary and alternative medicine techniques in the management of allergic disorders Over 100 outstanding illustrations Key concepts, management protocols, and recent references that deliver s a highly accessible overview of today's allergy practice



The Progress of Experiment

The Progress of Experiment Author Harry M. Marks
ISBN-10 0521785618
Release 2000-10-02
Pages 258
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Explores the origins of contemporary drug regulation and the modern clinical trial.



40 Days of Dating

40 Days of Dating Author Jessica Walsh
ISBN-10 9781613127155
Release 2015-01-20
Pages 304
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When New York–based graphic designers and long-time friends Timothy Goodman and Jessica Walsh found themselves single at the same time, they decided to try an experiment. The old adage says that it takes 40 days to change a habit—could the same be said for love? So they agreed to date each other for 40 days, record their experiences in questionnaires, photographs, videos, texts, and artworks, and post the material on a website they would create for this purpose. What began as a small experiment between two friends became an Internet sensation, drawing 5 million unique (and obsessed) visitors from around the globe to their site and their story since it was launched in July 2013. 40 Days of Dating: An Experiment is a beautifully designed, expanded look at the experiment and the results, including a great deal of material that never made it onto the site, such as who they were as friends and individuals before the 40 days and who they have become since. Note: 40 Days of Dating has a special binding that allows it to open very flat by attaching the endpapers to the inside covers.



Diphtheria Serum as a Technological Object

Diphtheria Serum as a Technological Object Author Jonathan Simon
ISBN-10 9781498531481
Release 2016-12-27
Pages 174
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Introduced in 1894 as a treatment for a deadly childhood disease, the diphtheria serum stands as a milestone in pharmaceutical history. Diphtheria Serum as a Technological Object: A Philosophical Analysis of Serotherapy in France 1894-1900 considers the production and use of this serum in France, analyzing the drug in terms of a technological object. To do this, Jonathan Simon draws on the philosophy of technology, exploring the application of this approach to medical drugs and suggesting how such an analysis can in turn contribute to this domain of philosophy. Starting with the manufacture of the serum from horses’ blood, Simon then considers the processes involved in transforming the blood serum into a legal medical drug and establishing its efficacy as a treatment against diphtheria. The book looks at the place the drug assumed in French society at the time, as well as the legal and political implications of its manufacture and use. All these elements are deployed to characterize a specifically French serum, as the author argues that the constitution of the drug in its full sense is not only technical but also social, political, and legal. Considering the serum as technological object facilitates a philosophical reflection on the nature of medical drugs in general by means of a thorough analysis of this particular historical example. The insights offered in this book will be of interest to students and scholars working on the philosophy of technology, particularly the medical sciences, as well as to historians of medicine, particularly those interested in the history of pharmacy.



The Glaucoma Book

The Glaucoma Book Author Paul N. Schacknow
ISBN-10 9780387767000
Release 2010-06-10
Pages 1043
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Complete evidence-based medical and surgical management of glaucoma for both the general ophthalmologist in practice and residents The only book that covers the new generation of glaucoma procedures including trabectome, trabecular bypass and canaloplasty, by the experts who developed them Includes the latest laser treatments for glaucoma including micro diode and titanium saphire trabeculoplasty as well as laser from an external approach The most comprehensive coverage of the optic nerve and the importance of nerve fiber layer hemorrhage Provides an integrated approach to neovascular glaucoma merging treatment to the retina, with the use of new anti-VEGF drugs, tubes, and shunts to achieve the best outcome Integrates clinical science with basic science to outline the next steps in glaucoma therapy



Clinical Epidemiology Evidence Based Medicine

Clinical Epidemiology   Evidence Based Medicine Author David L. Katz
ISBN-10 9781506319650
Release 2001-08-21
Pages 320
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"The presentation is consistently excellent. One, the writing is lucid and organized in a way that should be very natural for the clinical reader. Two, the text requires no background in mathematics and uses a minimum of symbols. And, three, the methodological concepts and clinical issues are well integrated through a number of carefully prepared and comprehensive examples." Greg Samsa, Associate Director, Duke Center for Clinical Health Policy Research If a patient is older or younger than, sicker or healthier than, taller or shorter than or simply different from the subjects of a study, do the results pertain? Clinical Epidemiology & Evidence-based Medicine is a resource for all health-care workers involved in applying evidence to the care of their patients. Using clinical examples and citing liberally from the peer-reviewed literature, the book shows how statistical principles can improve medical decisions. Plus, as Katz shows how probability, risk and alternatives are fundamental considerations in all clinical decisions, he demonstrates the intuitive basis for using clinical epidemiolgy as a science underlying medical decisions. After reading this text, the practitioner should be better able to access, interpret, and apply evidence to patient care as well as better understand and control the process of medical decision making.



The Generation of Diversity

The Generation of Diversity Author Alfred I. Tauber
ISBN-10 0674001826
Release 2000
Pages 508
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This book is an intellectual history of the major theoretical problem in immunology and its resolution in the post-World War II period. In recent years immunology has been one of the most exciting--and successful--fields of biomedical research; this book provides essential background for understanding the conceptual conflicts occurring in the field.



Immunity

Immunity Author Alfred I. Tauber
ISBN-10 9780190651268
Release 2017-01-02
Pages 304
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Modern immunology traditionally conceives of the immune system as providing defense against pathogens. Alfred I. Tauber criticizes this conception of immunity as too narrow, because it discounts much of the immune system's other normal functions. These include active tolerance of nutritional exchanges with the environment and the stabilization of cooperative relationships with resident micro-organisms. An expanded account extends immunity's functional role from singular 'defense' to broadened discernment of environmental 'exchange.' This ecological perspective has profound theoretical implications, for the basic notion of immune identity is reconfigured: highlighting the organism as a holobiont (a consortium of diverse organisms living in cooperative relationships) challenges prevailing concepts of individuality and the self/nonself dichotomy heretofore organizing immune theory. Indeed, if theoretical interest is focused on the challenges of maintaining immune balance in the full ecological context of the organism, then immune regulation assumes new complexity. Tauber maintains that the key to unravelling that puzzle requires a critical re-assessment of the cognitive processes that underlie immune effector functions. Accordingly, he provides the outline of a re-formulated 'cognitive paradigm' that dispenses with agent-based models and adopts an ecologically conceived understanding of perception and information processing. The implications of this revised configuration of immunity and its deconstructed notions of individuality and selfhood have wide significance for philosophers and life scientists working in immunology, ecology, and the cognitive sciences.



Nutrition and Rheumatic Disease

Nutrition and Rheumatic Disease Author Laura A. Coleman
ISBN-10 1597454036
Release 2008-03-11
Pages 296
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In this book, experts provide a comprehensive review of current knowledge regarding nutrition and dietary management for the complex set of rheumatic conditions. Within the disease-specific chapters, the authors present a historical perspective, a discussion of the major clinical features, current management and treatment, a review of the literature related to nutritional status and diet, and dietary recommendations, based on current scientific evidence. The field of rheumatic diseases includes a wide variety of pathologic processes. This book will greatly benefit physicians specializing in internal medicine, family practice, and rheumatology.



The Spirit Catches You and You Fall Down

The Spirit Catches You and You Fall Down Author Anne Fadiman
ISBN-10 9780374533403
Release 2012-04-24
Pages 368
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A study in the collision between Western medicine and the beliefs of a traditional culture focuses on a hospitalized child of Laotian immigrants whose belief that illness is a spiritual matter comes into conflict with doctors' methods.



Effects of Microbes on the Immune System

Effects of Microbes on the Immune System Author Madeleine W. Cunningham
ISBN-10 UOM:39015047554996
Release 2000
Pages 662
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Written by the foremost leaders in immunologic research, this volume is a definitive text on the ways in which bacteria, viruses, parasites, and fungi affect the immune response in the host. The book synthesizes recent discoveries on the various mechanisms by which microbes subvert the immune response and on the role of these immunologic mechanisms in the pathogenesis of infectious diseases. Each chapter examines a particular group of infectious pathogens and focuses on the immunobiology of the disease. A separate section explores potential vaccines for mucosal or conventional delivery.