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Amphioxus Immunity

Amphioxus Immunity Author An-Long Xu
ISBN-10 9780128096475
Release 2015-12-31
Pages 304
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Amphioxus Immunity: Tracing the Origin of Human Immunity covers a remarkable range of information about Amphioxus and its evolutionary context. This compilation of what is currently known about Amphioxus, with a sharp focus on its immune system, includes 13 topics, such as: Amphioxus as a model for understanding the evolution of vertebrates basic knowledge of immunology immune organs and cells of amphioxus a genomic and transcriptomic view of the Amphioxus immunity pattern recognition system in Amphioxus transcription factors in Amphioxus the complement system of Amphioxus the oxidative burst system in Amphioxus immune effectors in Amphioxus lipid signaling of immune response in Amphioxus apoptosis in amphioxus; primitive adaptive immune system of Amphioxus and future research directions This valuable reference book is loaded with information that will be useful for anyone who wishes to learn more about the origin of vertebrates and adaptive immunity. Provides new evidence on the origin of the adaptive immune system, the evolution of innate immunity, and evolution-stage specific immune defense mechanisms Not only presents the cells and molecules involved in the adaptive immune response in Amphioxus, but also characterizes the origination and evolution of the gene families and pathways involved in innate immunity Includes much pioneering work, from the molecular, genomic, and cellular to the individual level



Amphioxus Immunity

Amphioxus Immunity Author Anlong Xu
ISBN-10 7030547152
Release 2018
Pages 289
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Amphioxus Immunity has been writing in one form or another for most of life. You can find so many inspiration from Amphioxus Immunity also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Amphioxus Immunity book for free.



Innate Immunity of Plants Animals and Humans

Innate Immunity of Plants  Animals and Humans Author Holger Heine
ISBN-10 9783540739302
Release 2007-12-07
Pages 241
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This book has been cunningly designed to provide an overview of our current knowledge about the innate immune systems of these three types of organisms. It not only covers the innate immune mechanisms and responses of such diverse organisms as plants, Cnidaria, Drosophila, urochordates and zebrafish, but also the major receptor systems in mammalians and humans. It delves too into the central defense mechanisms, antimicrobial peptides and the complement system.



The Evolution of the Immune System

The Evolution of the Immune System Author Davide Malagoli
ISBN-10 9780128020135
Release 2016-07-21
Pages 384
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The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors. Helps the reader gain a modern idea of the evolution of the immune systems in pluricellular organisms Provides a complete overview of the most studied and hot topics in comparative and evolutionary immunology Reflects the organisation of the immune system (cell-based, humoral [innate], humoral [adaptive]) without introducing further and misleading levels of organization Brings concepts and ideas on the evolution of the immune system to a wide readership



Skin Immune System SIS

Skin Immune System  SIS Author Jan D. Bos
ISBN-10 0849340160
Release 1997-04-10
Pages 752
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Immunodermatology is a field covering the majority of skin diseases, including the most prevalent onesin the general population. The Second Edition of Skin Immune System (SIS) discusses immune-mediated skin diseases and disease groups in which the SIS plays a role. It covers major findings in immunophysiology and immunopathology that have occurred since the introduction of the First Edition in 1990. As the subtitle indicates, the Second Edition adds a new emphasis on cutaneous immunology, and also includes new information on immune-based therapeutic interventions and methods, such as phototherapy and the immunological therapy of skin cancer. The book contains Part I, with introductory chapters; Part II, with descriptions of the cellular elements; and Part III, which describes the humoral and molecular components of SIS. Part IV follows to integrate the facts described in Parts II and III into concepts of pathophysiology. It contains a number of concepts entitled "response patterns" that describe how the constitutional elements of SIS work together. New in this edition are the descriptions of immunodermatological diseases individually described in Part V. Part VI is also all new and summarizes principles of immunotherapy.



Invertebrate Immunity

Invertebrate Immunity Author Kenneth Söderhäll
ISBN-10 1441980598
Release 2011-06-28
Pages 316
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It can be seen that the insects are the still attracting most research and researchers. However, an increasing interest is emerging to study new invertebrate groups, especially those where the genome is known. Even though Drosophila has been and still is an excellent model for immune studies, it is now clear that there are great differences between immune responses in Drosophila and that of several other invertebrates, which indeed calls for more research on other invertebrates



Physiology general pathology general therapeutics immunity

Physiology  general pathology  general therapeutics  immunity Author Charles Eucharist de Medicis Sajous
ISBN-10 OSU:32436011248463
Release 1903
Pages
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Physiology general pathology general therapeutics immunity has been writing in one form or another for most of life. You can find so many inspiration from Physiology general pathology general therapeutics immunity also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Physiology general pathology general therapeutics immunity book for free.



M1 M2 Macrophages The Arginine Fork in the Road to Health and Disease

M1 M2 Macrophages  The Arginine Fork in the Road to Health and Disease Author Charles Dudley Mills
ISBN-10 9782889194995
Release 2015-03-23
Pages
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Macrophages have unique and diverse functions necessary for survival. And, in humans (and other species), they are the most abundant leukocytes in tissues. The Innate functions of macrophages that are best known are their unusual ability to either “Kill” or “Repair”. Since killing is a destructive process and repair is a constructive process, it was stupefying how one cell could exhibit these 2 polar – opposite functions. However, in the late 1980’s, it was shown that macrophages have a unique ability to enzymatically metabolize Arginine to Nitric Oxide (NO, a gaseous non – specific killer molecule) or to Ornithine (a precursor of polyamines and collagen for repair). The dual Arginine metabolic capacity of macrophages provided a functional explanation for their ability to kill or repair. Macrophages predominantly producing NO are called M1 and those producing Ornithine are called M2. M1 and M2 – dominant responses occur in lower vertebrates, and in T cell deficient vertebrates being directly driven by Damage and Pathogen Associated Molecular Patterns (DAMP and PAMP). Thus, M1 and M2 are Innate responses that protect the host without Adaptive Immunity. In turn, M1/M2 is supplanting previous models in which T cells were necessary to “activate” or “alternatively activate” macrophages (the Th1/Th2 paradigm). M1 and M2 macrophages were named such because of the additional key findings that these macrophages stimulate Th1 and Th2 – like responses, respectively. So, in addition to their unique ability to kill or repair, macrophages also govern Adaptive Immunity. All of the foregoing would be less important if M1 or M2 – dominant responses were not observed in disease. But, they are. The best example to date is the predominance of M2 macrophages in human tumors where they act like wound repair macrophages and actively promote growth. More generally, humans have become M2 – dominant because sanitation, antibiotics and vaccines have lessened M1 responses. And, M2 dominance seems the cause of ever - increasing allergies in developed countries. Obesity represents a new and different circumstance. Surfeit energy (e.g., lipoproteins) causes monocytes to become M1 dominant in the vessel walls causing plaques. Because M1 or M2 dominant responses are clearly causative in many modern diseases, there is great potential in developing the means to selectively stimulate (or inhibit) either M1 or M2 responses to kill or repair, or to stimulate Th1 or Th2 responses, depending on the circumstance. The contributions here are meant to describe diseases of M1 or M2 dominance, and promising new methodologies to modulate the fungible metabolic machinery of macrophages for better health.



Origin and Evolution of the Vertebrate Immune System

Origin and Evolution of the Vertebrate Immune System Author L. Du Pasquier
ISBN-10 9783642596742
Release 2012-12-06
Pages 326
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The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo lecular contexts in which the mechanism was introduced.



Lectures on the Comparative Pathology of Inflammation

Lectures on the Comparative Pathology of Inflammation Author Elie Metchnikoff
ISBN-10 STANFORD:24503313871
Release 1893
Pages 218
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Lectures on the Comparative Pathology of Inflammation has been writing in one form or another for most of life. You can find so many inspiration from Lectures on the Comparative Pathology of Inflammation also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Lectures on the Comparative Pathology of Inflammation book for free.



Pathogen Host Interactions Antigenic Variation v Somatic Adaptations

Pathogen Host Interactions  Antigenic Variation v  Somatic Adaptations Author Ellen Hsu
ISBN-10 9783319208190
Release 2015-11-04
Pages 336
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This volume provides in-depth reviews of model systems that exemplify the arms race in host-pathogen interactions. Somatic adaptations are responsible for the individualization of biological responses to the environment, and the continual struggle between host immune systems and invading pathogens has given rise to corresponding processes that produce molecular variation. Whether in mollusks or human beings, various host somatic mechanisms have evolved independently, providing responses to counter rapidly-changing pathogens. The pathways they utilize can include non-heritable changes involving RNA and post-translational modifications, or changes that produce somatic DNA recombination and mutation. For infectious organisms such as protozoans and flatworms, antigenic variation is central to their survival strategy. Evolving the ability to evade the host immune system not only increases their chances of survival but is also necessary for successful re-infection within the host population.



Invertebrate Immunity

Invertebrate Immunity Author Karl Maramorosch
ISBN-10 9780323153263
Release 2012-12-02
Pages 378
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Invertebrate Immunity: Mechanisms of Invertebrate Vector-Parasite Relations consists of chapters presented at a workshop on invertebrate defense mechanisms, sponsored by the National Institutes of Health and held in Bethesda, Maryland, on April 17 and 18, 1974. Organized into four parts, having a total of 24 chapters, this book first discusses the barrier imposed by the gut of invertebrates to invading parasites. It then centers on the role of invertebrate hemocytes and other phagocytic cells in immunity, as well as the humoral defense mechanisms of these organisms. Other topics discussed include parasite encapsulation in insects, role of melanin in host-parasite interaction, and use of host hormones by insect parasites to make the host environment favorable for their growth and development. This book will be essential for those interested in comparative immunology and in invertebrate immune responses. It will be of special interest to entomologists, protozoologists, physicians, veterinarians, ecologists, pathologists, research workers, science teachers, and graduate students.



The Journal of Immunology

The Journal of Immunology Author
ISBN-10 UIUC:30112075226032
Release 2005
Pages
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The Journal of Immunology has been writing in one form or another for most of life. You can find so many inspiration from The Journal of Immunology also informative, and entertaining. Click DOWNLOAD or Read Online button to get full The Journal of Immunology book for free.



Fundamental Immunology

Fundamental Immunology Author William E. Paul
ISBN-10 9781451117837
Release 2012-12-10
Pages 1283
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Fundamental Immunology Seventh Edition This standard-setting textbook has defined the field of immunology since 1984, and is now in its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage readers expect. This comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Now full-color throughout the book's fully revised and updated content reflects the latest advances in the field. Current insights enhance readers' understanding of immune system function. The text's unique approach bridges the gap between basic immunology and the disease process. Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. Abundant illustrations and tables deliver essential information at a glance. Plus a convenient companion website features the fully searchable text with all references linked to PubMed. Look inside and discover... * Fully revised and updated content reflects the latest advances in the field. * Current insights enhance readers' understanding of immune system function * Unique approach bridges the gap between basic immunology and the disease process. * Extensive coverage of molecular biology explains the molecular dynamics underlying immune disorders and their treatment. * Abundant illustrations and tables deliver essential information at a glance. PLUS... A convenient companion website features the fully searchable text with all references linked to PubMed. Pick up your copy today!



Genome Research

Genome Research Author
ISBN-10 UOM:39015072624201
Release 2008
Pages
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Genome Research has been writing in one form or another for most of life. You can find so many inspiration from Genome Research also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Genome Research book for free.



Immunology at a Glance

Immunology at a Glance Author J. H. L. Playfair
ISBN-10 9781118447468
Release 2012-09-11
Pages 120
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Immunology at a Glance provides a user-friendly overview of the body’s defence mechanisms. Ideal from day one of a medical, biomedical or life science course, the text begins with a basic overview of both adaptive and innate immunity, before progressing to applied immunological concepts, which look at what happens when things go wrong, and how, in clinical medicine, each body system can be affected by immunity. Each double-page spread corresponds to a typical lecture and diagrammatically summarises core concepts in immunology, through accessible schematic diagrams on left-hand pages, with key points concisely summarised on the right-hand page. There are also self-assessment essay questions so you can test your knowledge. New for this 10th edition: Thoroughly updated and reorganised chapters offer greater clarity and easier understanding for those new to the subject New chapters on cytokine receptors and ‘Immunology in the Laboratory’ A completely re-written section on autoimmunity A brand new companion website featuring self-assessment questions and PowerPoint slides of images from the book, ideal for teaching and revision at www.ataglanceseries.com/immunology Immunology at a Glance is the ideal companion for anyone about to start a new course in immunology and will appeal to medical and biomedical science students. Perfect for exam preparation, it provides the concepts and frameworks you need to succeed in your exam.



Introduction to Evolutionary Genomics

Introduction to Evolutionary Genomics Author Naruya Saitou
ISBN-10 9781447153047
Release 2014-01-22
Pages 461
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This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Features: introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection; presents a brief evolutionary history of life from the primordial seas to the emergence of humans; describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans; reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building; discusses databases of genome sequences and related information, evolutionary distances, and population genomics; provides supplementary material at an associated website.