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Bioinformatics

Bioinformatics Author Pierre Baldi
ISBN-10 026202506X
Release 2001
Pages 452
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A guide to machine learning approaches and their application to the analysis of biological data.



Deep Learning

Deep Learning Author Ian Goodfellow
ISBN-10 9780262035613
Release 2016-11-18
Pages 800
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An introduction to a broad range of topics in deep learning, covering mathematical and conceptual background, deep learning techniques used in industry, and research perspectives.



Introduction to Machine Learning

Introduction to Machine Learning Author Ethem Alpaydin
ISBN-10 9780262028189
Release 2014-08-29
Pages 640
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The goal of machine learning is to program computers to use example data or past experience to solve a given problem. Many successful applications of machine learning exist already, including systems that analyze past sales data to predict customer behavior, optimize robot behavior so that a task can be completed using minimum resources, and extract knowledge from bioinformatics data. Introduction to Machine Learning is a comprehensive textbook on the subject, covering a broad array of topics not usually included in introductory machine learning texts. Subjects include supervised learning; Bayesian decision theory; parametric, semi-parametric, and nonparametric methods; multivariate analysis; hidden Markov models; reinforcement learning; kernel machines; graphical models; Bayesian estimation; and statistical testing.Machine learning is rapidly becoming a skill that computer science students must master before graduation. The third edition of Introduction to Machine Learning reflects this shift, with added support for beginners, including selected solutions for exercises and additional example data sets (with code available online). Other substantial changes include discussions of outlier detection; ranking algorithms for perceptrons and support vector machines; matrix decomposition and spectral methods; distance estimation; new kernel algorithms; deep learning in multilayered perceptrons; and the nonparametric approach to Bayesian methods. All learning algorithms are explained so that students can easily move from the equations in the book to a computer program. The book can be used by both advanced undergraduates and graduate students. It will also be of interest to professionals who are concerned with the application of machine learning methods.



Introduction to Machine Learning and Bioinformatics

Introduction to Machine Learning and Bioinformatics Author Sushmita Mitra
ISBN-10 9781420011784
Release 2008-06-05
Pages 384
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Lucidly Integrates Current Activities Focusing on both fundamentals and recent advances, Introduction to Machine Learning and Bioinformatics presents an informative and accessible account of the ways in which these two increasingly intertwined areas relate to each other. Examines Connections between Machine Learning & Bioinformatics The book begins with a brief historical overview of the technological developments in biology. It then describes the main problems in bioinformatics and the fundamental concepts and algorithms of machine learning. After forming this foundation, the authors explore how machine learning techniques apply to bioinformatics problems, such as electron density map interpretation, biclustering, DNA sequence analysis, and tumor classification. They also include exercises at the end of some chapters and offer supplementary materials on their website. Explores How Machine Learning Techniques Can Help Solve Bioinformatics Problems Shedding light on aspects of both machine learning and bioinformatics, this text shows how the innovative tools and techniques of machine learning help extract knowledge from the deluge of information produced by today’s biological experiments.



Machine Learning Approaches to Bioinformatics

Machine Learning Approaches to Bioinformatics Author
ISBN-10 9789814466783
Release
Pages
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Machine Learning Approaches to Bioinformatics has been writing in one form or another for most of life. You can find so many inspiration from Machine Learning Approaches to Bioinformatics also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Machine Learning Approaches to Bioinformatics book for free.



Introduction to Computational Biology

Introduction to Computational Biology Author Michael S. Waterman
ISBN-10 9781351437080
Release 2018-05-02
Pages 448
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Biology is in the midst of a era yielding many significant discoveries and promising many more. Unique to this era is the exponential growth in the size of information-packed databases. Inspired by a pressing need to analyze that data, Introduction to Computational Biology explores a new area of expertise that emerged from this fertile field- the combination of biological and information sciences. This introduction describes the mathematical structure of biological data, especially from sequences and chromosomes. After a brief survey of molecular biology, it studies restriction maps of DNA, rough landmark maps of the underlying sequences, and clones and clone maps. It examines problems associated with reading DNA sequences and comparing sequences to finding common patterns. The author then considers that statistics of pattern counts in sequences, RNA secondary structure, and the inference of evolutionary history of related sequences. Introduction to Computational Biology exposes the reader to the fascinating structure of biological data and explains how to treat related combinatorial and statistical problems. Written to describe mathematical formulation and development, this book helps set the stage for even more, truly interdisciplinary work in biology.



Reinforcement Learning

Reinforcement Learning Author Richard S. Sutton
ISBN-10 9781461536185
Release 2012-12-06
Pages 172
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Reinforcement learning is the learning of a mapping from situations to actions so as to maximize a scalar reward or reinforcement signal. The learner is not told which action to take, as in most forms of machine learning, but instead must discover which actions yield the highest reward by trying them. In the most interesting and challenging cases, actions may affect not only the immediate reward, but also the next situation, and through that all subsequent rewards. These two characteristics -- trial-and-error search and delayed reward -- are the most important distinguishing features of reinforcement learning. Reinforcement learning is both a new and a very old topic in AI. The term appears to have been coined by Minsk (1961), and independently in control theory by Walz and Fu (1965). The earliest machine learning research now viewed as directly relevant was Samuel's (1959) checker player, which used temporal-difference learning to manage delayed reward much as it is used today. Of course learning and reinforcement have been studied in psychology for almost a century, and that work has had a very strong impact on the AI/engineering work. One could in fact consider all of reinforcement learning to be simply the reverse engineering of certain psychological learning processes (e.g. operant conditioning and secondary reinforcement). Reinforcement Learning is an edited volume of original research, comprising seven invited contributions by leading researchers.



Learning with Kernels

Learning with Kernels Author Bernhard Schölkopf
ISBN-10 0262194759
Release 2002-01
Pages 626
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A comprehensive introduction to Support Vector Machines and related kernel methods.



Machine Learning in Non Stationary Environments

Machine Learning in Non Stationary Environments Author Masashi Sugiyama
ISBN-10 9780262300438
Release 2012-03-30
Pages 280
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As the power of computing has grown over the past few decades, the field of machine learning has advanced rapidly in both theory and practice. Machine learning methods are usually based on the assumption that the data generation mechanism does not change over time. Yet real-world applications of machine learning, including image recognition, natural language processing, speech recognition, robot control, and bioinformatics, often violate this common assumption. Dealing with non-stationarity is one of modern machine learning's greatest challenges. This book focuses on a specific non-stationary environment known as covariate shift, in which the distributions of inputs (queries) change but the conditional distribution of outputs (answers) is unchanged, and presents machine learning theory, algorithms, and applications to overcome this variety of non-stationarity. After reviewing the state-of-the-art research in the field, the authors discuss topics that include learning under covariate shift, model selection, importance estimation, and active learning. They describe such real world applications of covariate shift adaption as brain-computer interface, speaker identification, and age prediction from facial images. With this book, they aim to encourage future research in machine learning, statistics, and engineering that strives to create truly autonomous learning machines able to learn under non-stationarity.



Data Mining for Bioinformatics

Data Mining for Bioinformatics Author Sumeet Dua
ISBN-10 9780849328015
Release 2012-11-06
Pages 348
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Covering theory, algorithms, and methodologies, as well as data mining technologies, Data Mining for Bioinformatics provides a comprehensive discussion of data-intensive computations used in data mining with applications in bioinformatics. It supplies a broad, yet in-depth, overview of the application domains of data mining for bioinformatics to help readers from both biology and computer science backgrounds gain an enhanced understanding of this cross-disciplinary field. The book offers authoritative coverage of data mining techniques, technologies, and frameworks used for storing, analyzing, and extracting knowledge from large databases in the bioinformatics domains, including genomics and proteomics. It begins by describing the evolution of bioinformatics and highlighting the challenges that can be addressed using data mining techniques. Introducing the various data mining techniques that can be employed in biological databases, the text is organized into four sections: Supplies a complete overview of the evolution of the field and its intersection with computational learning Describes the role of data mining in analyzing large biological databases—explaining the breath of the various feature selection and feature extraction techniques that data mining has to offer Focuses on concepts of unsupervised learning using clustering techniques and its application to large biological data Covers supervised learning using classification techniques most commonly used in bioinformatics—addressing the need for validation and benchmarking of inferences derived using either clustering or classification The book describes the various biological databases prominently referred to in bioinformatics and includes a detailed list of the applications of advanced clustering algorithms used in bioinformatics. Highlighting the challenges encountered during the application of classification on biological databases, it considers systems of both single and ensemble classifiers and shares effort-saving tips for model selection and performance estimation strategies.



Machine Learning in Bioinformatics

Machine Learning in Bioinformatics Author Yanqing Zhang
ISBN-10 0470397411
Release 2009-02-23
Pages 400
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An introduction to machine learning methods and their applications to problems in bioinformatics Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. From an internationally recognized panel of prominent researchers in the field, Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics. Coverage includes: feature selection for genomic and proteomic data mining; comparing variable selection methods in gene selection and classification of microarray data; fuzzy gene mining; sequence-based prediction of residue-level properties in proteins; probabilistic methods for long-range features in biosequences; and much more. Machine Learning in Bioinformatics is an indispensable resource for computer scientists, engineers, biologists, mathematicians, researchers, clinicians, physicians, and medical informaticists. It is also a valuable reference text for computer science, engineering, and biology courses at the upper undergraduate and graduate levels.



Bayesian Reasoning and Machine Learning

Bayesian Reasoning and Machine Learning Author David Barber
ISBN-10 9780521518147
Release 2012-02-02
Pages 697
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A practical introduction perfect for final-year undergraduate and graduate students without a solid background in linear algebra and calculus.



Kernel Methods and Machine Learning

Kernel Methods and Machine Learning Author S. Y. Kung
ISBN-10 9781139867634
Release 2014-04-17
Pages
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Offering a fundamental basis in kernel-based learning theory, this book covers both statistical and algebraic principles. It provides over 30 major theorems for kernel-based supervised and unsupervised learning models. The first of the theorems establishes a condition, arguably necessary and sufficient, for the kernelization of learning models. In addition, several other theorems are devoted to proving mathematical equivalence between seemingly unrelated models. With over 25 closed-form and iterative algorithms, the book provides a step-by-step guide to algorithmic procedures and analysing which factors to consider in tackling a given problem, enabling readers to improve specifically designed learning algorithms, build models for new applications and develop efficient techniques suitable for green machine learning technologies. Numerous real-world examples and over 200 problems, several of which are Matlab-based simulation exercises, make this an essential resource for graduate students and professionals in computer science, electrical and biomedical engineering. Solutions to problems are provided online for instructors.



Gaussian Processes for Machine Learning

Gaussian Processes for Machine Learning Author Carl Edward Rasmussen
ISBN-10 026218253X
Release 2006-01
Pages 248
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A comprehensive and self-contained introduction to Gaussian processes, which provide a principled, practical, probabilistic approach to learning in kernel machines.



Algorithms in Bioinformatics

Algorithms in Bioinformatics Author Wing-Kin Sung
ISBN-10 1420070347
Release 2009-11-24
Pages 407
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Thoroughly Describes Biological Applications, Computational Problems, and Various Algorithmic Solutions Developed from the author’s own teaching material, Algorithms in Bioinformatics: A Practical Introduction provides an in-depth introduction to the algorithmic techniques applied in bioinformatics. For each topic, the author clearly details the biological motivation and precisely defines the corresponding computational problems. He also includes detailed examples to illustrate each algorithm and end-of-chapter exercises for students to familiarize themselves with the topics. Supplementary material is available at http://www.comp.nus.edu.sg/~ksung/algo_in_bioinfo/ This classroom-tested textbook begins with basic molecular biology concepts. It then describes ways to measure sequence similarity, presents simple applications of the suffix tree, and discusses the problem of searching sequence databases. After introducing methods for aligning multiple biological sequences and genomes, the text explores applications of the phylogenetic tree, methods for comparing phylogenetic trees, the problem of genome rearrangement, and the problem of motif finding. It also covers methods for predicting the secondary structure of RNA and for reconstructing the peptide sequence using mass spectrometry. The final chapter examines the computational problem related to population genetics.



Foundations of Machine Learning

Foundations of Machine Learning Author Mehryar Mohri
ISBN-10 9780262304733
Release 2012-08-17
Pages 432
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This graduate-level textbook introduces fundamental concepts and methods in machine learning. It describes several important modern algorithms, provides the theoretical underpinnings of these algorithms, and illustrates key aspects for their application. The authors aim to present novel theoretical tools and concepts while giving concise proofs even for relatively advanced topics. Foundations of Machine Learning fills the need for a general textbook that also offers theoretical details and an emphasis on proofs. Certain topics that are often treated with insufficient attention are discussed in more detail here; for example, entire chapters are devoted to regression, multi-class classification, and ranking. The first three chapters lay the theoretical foundation for what follows, but each remaining chapter is mostly self-contained. The appendix offers a concise probability review, a short introduction to convex optimization, tools for concentration bounds, and several basic properties of matrices and norms used in the book.The book is intended for graduate students and researchers in machine learning, statistics, and related areas; it can be used either as a textbook or as a reference text for a research seminar.



Information Theory Inference and Learning Algorithms

Information Theory  Inference and Learning Algorithms Author David J. C. MacKay
ISBN-10 0521642981
Release 2003-09-25
Pages 628
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Fun and exciting textbook on the mathematics underpinning the most dynamic areas of modern science and engineering.