Download or read online books in PDF, EPUB and Mobi Format. Click Download or Read Online button to get book now. This site is like a library, Use search box in the widget to get ebook that you want.

Biomarkers and Biosensors

Biomarkers and Biosensors Author Ajit Sadana
ISBN-10 9780444537959
Release 2014-12-08
Pages 702
Download Link Click Here

Biomarkers and Biosensors offers thorough coverage of biomarker/biosensor interaction, current research trends, and future developments in applications of drug discovery. This book is useful to researchers in this field as well as clinicians interested in new developments in early detection and diagnosis of disease or the mode of operation of biomarkers. Biomarkers and Biosensors also emphasizes kinetics, and clearly delineates how this influences the biomarker market. Offers thorough coverage of the kinetics of biomarker interaction with the biosensor surface Provides evidence-based approach to evaluate effectiveness Provides pharmaceutical chemists the possibilities and methodology in assessing the effectiveness of new drugs Provides the information needed for the selection of the best biomarker for a specific application



Handbook of Biosensors and Biosensor Kinetics

Handbook of Biosensors and Biosensor Kinetics Author Ajit Sadana
ISBN-10 0080932851
Release 2010-08-26
Pages 536
Download Link Click Here

Biosensors are essential to an ever-expanding range of applications, including healthcare; drug design; detection of biological, chemical, and toxic agents; environmental monitoring; biotechnology; aviation; physics; oceanography; and the protection of civilian and engineering infrastructures. This book, like the previous five books on biosensors by this author (and one by the co-author), addresses the neglected areas of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces. Topics are covered in a comprehensive fashion, with homogeneous presentation for the benefit of the reader. The contributors address the economic aspects of biosensors and incorporate coverage of biosensor fabrication and nanobiosensors, among other topics. The comments, comparison, and discussion presented provides a better perspective of where the field of biosensors is heading. Serves as a comprehensive resource on biosensor analysis Examines timely topics such as biosensor fabrication and nanobiosensors Covers economic aspects and medical applications (e.g., the role of analytes in controlling diabetes)



A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces

A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces Author Ajit Sadana
ISBN-10 9780444638823
Release 2018-07-31
Pages 337
Download Link Click Here

A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces analyzes the kinetics of binding and dissociation of different analytes by different biosensor techniques, demonstrating and then comparing each. Emphasis is placed on newer instrumentation techniques, such as SPRi (surface plasmon resonance imaging), and classical techniques, such as SPR (surface plasmon resonance), and finally, DNA biosensors and nanobiosensors. In addition, a final capstone chapter includes biosensor economics. These topics are all covered in one comprehensive book in a way that cannot be found elsewhere. Analyzes the kinetics of binding on biosensor surfaces Presents and compares different biosensor techniques Provides insights into the binding and dissociation mechanisms of analytes on biosensor surfaces Links the heterogeneity of biosensor surfaces to dissociation rate coefficients



Fractal Analysis of the Binding and Dissociation Kinetics for Different Analytes on Biosensor Surfaces

Fractal Analysis of the Binding and Dissociation Kinetics for Different Analytes on Biosensor Surfaces Author Ajit Sadana
ISBN-10 0080555012
Release 2007-12-20
Pages 372
Download Link Click Here

Biosensors are finding increasing applications in different areas. Over the last few years the areas where biosensors may be used effectively has increased dramatically. This book like the previous four books on analyte-receptor binding and dissociation kinetics by this author addresses the often neglected area. The kinetics of binding and dissociation in solution to appropriate receptors immobilized on biosensor surfaces occurs under diffusional limitations on structured surfaces. The receptors immobilized on the biosensor surface contribute to the degree of heterogeneity on the sensor chip surface. The fractal analysis examples presented throughout the book provide a convenient means to make quantitative the degree of heterogeneity present on the sensor surface, and relates it to the binding and dissociation rate coefficients. The fractal dimension is a quantitative measure of the degree of heterogeneity present on the biosensor surface. The book emphasizes medially-oriented examples. The detection of disease-related analytes is also emphasized. The intent being that if intractable and insidious diseases are detected earlier, they will be controlled better, eventually leading to a better prognosis. Chapter 3 is a new chapter that emphasizes enhancing the relevant biosensor performance parameters such as sensitivity, stability, selectivity, response time, etc. As usual, as done in previous books by this author, the last chapter provides an update of the economics involved in biosensors, and the difficulties encounters in starting-up a biosensor company. - Modelling of binding and dissociation kinetics of analyte-receptor reactions on biosensor surfaces: provides physical insights into these reactions occurring on biosensor surfaces. Very few researchers even attempt to analyze the kinetics of these types of reactions. - Fractal analysis used to model the binding and dissociation kinetics: original and unique approach. - Economic analysis provided in the last chapter: helps balance the book; besides providing much-needed information not available in the open literature. - Emphasis on improving biosensor performance parameters: helps make biosensors better. - Empahsis on medically-related analytes: helps in prognosis of diseases.



Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals

Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals Author Ajit Sadana
ISBN-10 008046369X
Release 2006-08-08
Pages 384
Download Link Click Here

The application of biosensors is expanding in different areas. These are portable and convenient devices that permit the rapid, accurate, and reliable detection of analytes of interest present either in the atmosphere or in aqueous or in liquid phases. The detection of glucose levels in blood for the effective management of diabetes is one. Though different biosensors have been designed for an increasing number of applications, the kinetics of binding (and dissociation) of analytes by the receptors on the biosensor surfaces has not been given enough attention in the open literature. This is a very important area of investigation since it significantly impacts biosensor performance parameters such as stability, sensitivity, selectivity, response time, regenerability, etc. Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals addresses this critical need besides helping to correct or demonstrate the need to modify the present software available with commercial biosensors that determines the kinetics of analyte-receptor reactions on biosensor surfaces. * first book to provide detailed kinetic analysis of the binding and dissociation reactions that are occuring on the biosensor surface * addresses the area of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces * provides physical insights into reactions occuring on biosensor surfaces



Immunosensing for Detection of Protein Biomarkers

Immunosensing for Detection of Protein Biomarkers Author Huangxian Ju
ISBN-10 9780081020005
Release 2017-05-18
Pages 304
Download Link Click Here

Immunosensing for Detection of Protein Biomarkers not only introduces the principles, methods, and classification of immunoassay, but also presents the latest achievements in areas such as electrochemical immunosensors, nanoprobe-based immunoassay, chemiluminescence immunoassay, electrochemiluminescent immunoassay, multianalyte immunoassay, optical imaging for immunoassay, signal amplification for immunoassay, and so on. In recent years, immunosensing and immunoassay methods have attracted considerable interest due to their applications in different fields, particularly clinical diagnosis. Although a large number of academic papers in immunosensing and immunoassay have been published in different journals recently, it is still a difficult and time-consuming task for researchers, especially those new to the area, to understand the principles, methods, and research progress of immunosensing. Based on the research experience of the authors and their research groups, this book offers readers with new research ideas to develop immunosensing methodology. As a monograph, it offers deeper and more complete coverage than review papers, which only report certain aspects of progress. Grounded in the research experience of Professor Ju’s research group, the book focuses on immunosensing for detection of protein biomarkers, summarizing understanding, research, and practice on immunosensing methodology in detection of protein biomarkers. Presents the latest research and thinking on immunosensing for detection of protein biomarkers Offers current techniques, and looks to the development of new methodologies Offers the latest developments in various aspects of immunosensing, including electrochemiluminescent immunoassay, multianalyte immunoassay, optical imaging immunoassay, and signal amplification immunoassay Offers readers new ideas to research and develop immunosensing methodologies for the future



Biosensors and Cancer

Biosensors and Cancer Author Victor R. Preedy
ISBN-10 9781578087341
Release 2012-07-27
Pages 424
Download Link Click Here

Understanding the importance and application of biosensors is complicated by the diverse range of methods and applications. Furthermore, existing texts are somewhat technical in nature, making it difficult for the novice. This book disseminates information on biosensors in a readable way, suitable to a wide audience with varying levels of experience. Topics include optical imaging, surface plasmon resonance, microcantilevers, electrochemistry, aptamers, fluorescence, electrochemistry, nanobiosensors, and nanowires.



Biosensors for Medical Applications

Biosensors for Medical Applications Author Séamus Higson
ISBN-10 9780857097187
Release 2012-08-21
Pages 360
Download Link Click Here

Biomedical sensors are an essential tool in the detection and monitoring of a wide range of medical conditions from cancer to Parkinson’s disease. Biosensors for medical applications provides a comprehensive review of established, cutting edge and future trends in biomedical sensors and their applications. Part one focuses on key principles and transduction approaches, reviewing electrochemical, piezoelectric and nano-sized biosensors. Impedence interrogated affinity biosensors for medical applications and practical applications of enzyme biosensors are explored, before part two goes on to review specific medical applications. Biosensors for DNA and RNA detection and characterization, disease biomarker detection, and the use of affibodies as an alternative to antibodies in cancer marker biosensors are investigated, along with biosensors for drug testing and discovery, non-invasive measurements, and wearable biosensors for medical applications. With its distinguished editor and international team of expert contributors, Biosensors for medical applications is an essential guide for all those involved in the research, design, production and use of medical biosensors. Provides a comprehensive review of established, cutting edge and future trends in biomedical sensors and their applications Examines key principles and transduction approaches, reviewing electrochemical, piezoelectric and nano-sized biosensors Reviews biosensors for DNA and RNA detection and characterisation, disease biomarker detection, and the use of affibodies as an alternative to antibodies in cancer marker biosensors



Nanotechnology in Biology and Medicine

Nanotechnology in Biology and Medicine Author Tuan Vo-Dinh
ISBN-10 9781315356952
Release 2017-10-03
Pages 740
Download Link Click Here

The second edition of Nanotechnology in Biology and Medicine is intended to serve as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of nanotechnology in life sciences. This technology, which is on the scale of molecules, has enabled the development of devices smaller and more efficient than anything currently available. To understand complex biological nanosystems at the cellular level, we urgently need to develop a next-generation nanotechnology tool kit. It is believed that the new advances in genetic engineering, genomics, proteomics, medicine, and biotechnology will depend on our mastering of nanotechnology in the coming decades. The integration of nanotechnology, material sciences, molecular biology, and medicine opens the possibility of detecting and manipulating atoms and molecules using nanodevices, which have the potential for a wide variety of biological research topics and medical uses at the cellular level. This book presents the most recent scientific and technological advances of nanotechnology for use in biology and medicine. Each chapter provides introductory material with an overview of the topic of interest; a description of methods, protocols, instrumentation, and applications; and a collection of published data with an extensive list of references for further details. The goal of this book is to provide a comprehensive overview of the most recent advances in instrumentation, methods, and applications in areas of nanobiotechnology, integrating interdisciplinary research and development of interest to scientists, engineers, manufacturers, teachers, and students.



Biosensors and Nanotechnology

Biosensors and Nanotechnology Author Zeynep Altintas
ISBN-10 9781119065012
Release 2017-12-18
Pages 400
Download Link Click Here

General introduction to biosensors and recognition receptors -- Biomarkers in health care -- The use of nanomaterials and microfluidics in medical diagnostics -- SPR-based biosensor technologies in disease detection and diagnostics -- Piezoelectric-based biosensor technologies in disease detection and diagnostics -- Electrochemical-based biosensor technologies in disease detection and diagnostics -- MEMS-based cell counting methods -- Lab-on-a-chip platforms for disease detection and diagnosis -- Applications of quantum dots in biosensors and diagnostics -- Applications of molecularly imprinted nanostructures in biosensors and diagnostics -- Smart nanomaterial's : applications in biosensors and diagnostics -- Applications of magnetic nanomaterial's in biosensors and diagnostics -- Graphene applications in biosensors and diagnostics -- Optical biosensors and applications to drug discovery for cancer cases -- Biosensors for detection of anticancer drug-DNA interactions



Nanobiosensors for Personalized and Onsite Biomedical Diagnosis

Nanobiosensors for Personalized and Onsite Biomedical Diagnosis Author Pranjal Chandra
ISBN-10 9781849199506
Release 2016-07
Pages 624
Download Link Click Here

The critical goal of nanobiosensors is to detect any biochemical and/or biophysical signal related to a specific disease at the level of a single or few molecules. Nanobiosensors have been successful for in vitro as well as in vivo detection of several biomolecules. It is expected that this technology will revolutionize point-of-care and personalized diagnostics, and will be extremely applicable for early disease detection. This book starts with a brief introduction of the biosensors and then focuses mainly on the emerging nanobiosensor technologies which are geared towards onsite clinical applications and those which can be used as a personalized diagnostic device. Written by an international team of researchers who are actively developing these technologies, Nanobiosensors for Personalized and Onsite Biomedical Diagnosis covers the latest advances in the field of biosensors and biosensing applications. This important book includes an assessment of some current and emerging technologies for detecting protein biomarkers and other potential cancer biomarkers and is essential reading for researchers and graduate students in the field. Medics including radiologists and clinicians will also find it invaluable.



Biosensors and Molecular Technologies for Cancer Diagnostics

Biosensors and Molecular Technologies for Cancer Diagnostics Author Keith E. Herold
ISBN-10 9781439841662
Release 2012-05-29
Pages 844
Download Link Click Here

Bridging the gap between research and clinical application, Biosensors and Molecular Technologies for Cancer Diagnostics explores the use of biosensors as effective alternatives to the current standard methods in cancer diagnosis and detection. It describes the major aspects involved in detecting and diagnosing cancer as well as the basic elements of biosensors and their applications in detection and diagnostics. The book addresses cancer molecular diagnostics, including genomic and proteomic approaches, from the perspective of biosensors and biodetection. It explains how to measure and understand molecular markers using biosensors and discusses the medical advantages of rapid and accurate cancer diagnostics. It also describes optical, electrochemical, and optomechanical biosensor technologies, with a focus on cancer analysis and the clinical utility of these technologies for cancer detection, diagnostics, prognostics, and treatment. Making biosensor technology more accessible to molecular biologists, oncologists, pathologists, and engineers, this volume advances the integration of this technology into mainstream clinical practice. Through its in-depth coverage of a range of biosensors, the book shows how they can play instrumental roles in the early molecular diagnosis of cancer.



Electrogenerated Chemiluminescence

Electrogenerated Chemiluminescence Author Allen J. Bard
ISBN-10 0203027019
Release 2004-07-20
Pages 552
Download Link Click Here

The first source on this expanding analytical science, this reference explores advances in the instrumentation, design, and application of techniques with electrogenerated chemiluminescence (ECL), examining the use and impact of ECL-based assays in clinical diagnostics, life science research, environmental testing, food and water evaluation, and the detection of biowarfare agents. Compiled by the pioneer of this highly innovative technology, this volume provides contributions from 16 leading authorities. They discuss the simulation of ECL behavior using commercial software, summarize key characteristics of organic ECL systems, and cover developments in metal chelate ECL.



Semiconductor Based Sensors

Semiconductor Based Sensors Author Fan Ren
ISBN-10 9789813146747
Release 2016-08-26
Pages 496
Download Link Click Here

This book provides a comprehensive summary of the status of emerging sensor technologies and provides a framework for future advances in the field. Chemical sensors have gained in importance in the past decade for applications that include homeland security, medical and environmental monitoring and also food safety. A desirable goal is the ability to simultaneously analyze a wide variety of environmental and biological gases and liquids in the field and to be able to selectively detect a target analyte with high specificity and sensitivity. The goal is to realize real-time, portable and inexpensive chemical and biological sensors and to use these as monitors for handheld gas, environmental pollutant, exhaled breath, saliva, urine, or blood, with wireless capability. In the medical area, frequent screening can catch the early development of diseases, reduce the suffering of patients due to late diagnoses, and lower the medical cost. For example, a 96% survival rate has been predicted in breast cancer patients if the frequency of screening is every three months. This frequency cannot be achieved with current methods of mammography due to high cost to the patient and invasiveness (radiation). In the area of detection of medical biomarkers, many different methods, including enzyme-linked immunsorbent assay (ELISA), particle-based flow cytometric assays, electrochemical measurements based on impedance and capacitance, electrical measurement of microcantilever resonant frequency change, and conductance measurement of semiconductor nanostructures, gas chromatography (GC), ion chromatography, high density peptide arrays, laser scanning quantitiative analysis, chemiluminescence, selected ion flow tube (SIFT), nanomechanical cantilevers, bead-based suspension microarrays, magnetic biosensors and mass spectrometry (MS) have been employed. Depending on the sample condition, these methods may show variable results in terms of sensitivity for some applications and may not meet the requirements for a handheld biosensor.



Label Free Biosensing

Label Free Biosensing Author Michael J. Schöning
ISBN-10 9783319752204
Release 2018-07-20
Pages 480
Download Link Click Here

This volume summarizes the state-of-the-art technologies, key advances and future trends in the field of label-free biosensing. It provides detailed insights into the different types of solid-state, label-free biosensors, their underlying transducer principles, advanced materials utilized, device-fabrication techniques and various applications. The book offers graduate students, academic researchers, and industry professionals a comprehensive source of information on all facets of label-free biosensing and the future trends in this flourishing field. Highlights of the subjects covered include label-free biosensing with: · semiconductor field-effect devices such as nanomaterial-modified capacitive electrolyte-insulator-semiconductor structures, silicon nanowire transistors, III-nitride semiconductor devices and light-addressable potentiometric sensors · impedimetric biosensors using planar and 3D electrodes · nanocavity and solid-state nanopore devices · carbon nanotube and graphene/graphene oxide biosensors · electrochemical biosensors using molecularly imprinted polymers · biomimetic sensors based on acoustic signal transduction · enzyme logic systems and digital biosensors based on the biocomputing concept · heat-transfer as a novel transducer principle · ultrasensitive surface plasmon resonance biosensors · magnetic biosensors and magnetic imaging devices



NanoOncology An Issue of Clinics in Laboratory Medicine E Book

NanoOncology  An Issue of Clinics in Laboratory Medicine   E Book Author Kewal Jain
ISBN-10 9781455742899
Release 2012-03-26
Pages 120
Download Link Click Here

This issue of Clinics in Laboratory Medicine includes the following topics: Detection of cancer biomarkers by cerium oxide nanoparticles; Quantum dot-based assays for cancer biomarkers; Monoclonal antibody conjugated fluorescent magnetic nanoparticles for in vivo diagnosis of cancer; RNA quantification with gold nanoprobes for cancer diagnostics; Nanostructured silica materials for imaging in cancer; and Nanoparticle-based cancer cell sorting.



Optical Biosensors

Optical Biosensors Author Frances S. Ligler
ISBN-10 0080564941
Release 2011-10-13
Pages 712
Download Link Click Here

Optical Biosensors, 2ed describes the principles of successful systems, examples of applications, and evaluates the advantages and deficiencies of each. It also addresses future developments on two levels: possible improvements in existing systems and emerging technologies that could provide new capabilities in the future. The book is formatted for ease of use and is therefore suitable for scientists and engineers, students and researcher at all levels in the field. * Comprehensive analysis and review of the underlying principles by optical biosensors * Updates and informs on all the latest developments and hot topic areas * Evaluates current methods showing the advantages and disadvantages of various systems involved