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Biomarkers in Marine Organisms

Biomarkers in Marine Organisms Author Ph. Garrigues
ISBN-10 008052804X
Release 2001-11-07
Pages 572
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Many previous studies and books have been dedicated to fundamental and developmental aspects of biomarkers. The purpose of this book is to provide, through various case studies, an overview of the practical use of biological markers in marine animals to evaluate the health effects of environmental contamination in marine ecosystems. More precisely, the book presents the results obtained during the development and application of biological markers as indicators of exposure/effect to toxic chemicals in marine environments, using diverse sentinel species such as fish, bivalves and crustaceans. An important aspect is also the publication of technical annexes that describe in detail the experimental procedures developed for both chemical and biochemical measurement.



Ecological Biomarkers

Ecological Biomarkers Author Claude Amiard-Triquet
ISBN-10 9781439880531
Release 2016-04-19
Pages 464
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Does a change, which affects a few biological macro-molecules, some cells, or a few individuals within a population, have any ecological significance that would allow the prediction of deleterious effects at higher levels of biological organization, namely the population, community, and ultimately the ecosystem? With contributions from experts in the field, Ecological Biomarkers: Indicators of Ecotoxicological Effects explores how biomarkers can be used to predict effects farther down the chain. It presents a synthesis of the state of the art in the methodology of biomarkers and its contribution to ecological risk assessment. This book describes the core biomarkers currently used in environmental research concerned with biological monitoring, biomarkers which correspond to the defences developed by living organisms in response to contaminants in their environment, and biomarkers that reveal biological damage resulting from contaminant stressors. It examines the efficacy of lysosomal biomarkers, immunotoxicity effects, behavioral disturbances, energy metabolism impairments, endocrine disruption measures, and genotoxicity as all indicative of probable toxic effects at higher biological levels. It is time to revisit the biological responses most ecologically relevant in the diagnosis of the health status of an aquatic environment well before it becomes unmanageable. Biomarkers provide a real possibility of delivering an easily measured marker at a simple level of biological organization that is predictably linked to a potentially ecologically significant effect at higher levels of biological organization. The text explores the latest knowledge and thinking on how to use biomarkers as tools for the assessment of environmental health and management.



Bioindicators Biomonitors

Bioindicators   Biomonitors Author Bernd A. Markert
ISBN-10 0080441777
Release 2003
Pages 997
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This book provides comprehensive single source coverage of bioindication/biomonitoring in the fields of ecology, ecotoxicology and environmental sciences; from the ecological basics to the effects of chemicals on the environment and the latest test strategies. Contributions by leading figures in ecology from around the world reflect the broad scope of current thinking and research, making this volume essential reading for informed professionals and students.



Aquatic Ecotoxicology

Aquatic Ecotoxicology Author Claude Amiard-Triquet
ISBN-10 9780128011768
Release 2015-06-11
Pages 518
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Aquatic Ecotoxicology: Advancing Tools for Dealing with Emerging Risks presents a thorough look at recent advances in aquatic ecotoxicology and their application in assessing the risk of well-known and emerging environmental contaminants. This essential reference, brought together by leading experts in the field, guides users through existing and novel approaches to environmental risk assessment, then presenting recent advances in the field of ecotoxicology, including omics-based technologies, biomarkers, and reference species. The book then demonstrates how these advances can be used to design and perform assays to discover the toxicological endpoints of emerging risks within the aquatic environment, such as nanomaterials, personal care products, PFOS and chemical mixtures. The text is an invaluable reference for any scientist who studies the effects of contaminants on organisms that live within aquatic environments. Provides the latest perspectives on emerging toxic risks to aquatic environments, such as nanomaterials, pharmaceuticals, chemical mixtures, and perfluorooctane sulfonate (PFOS) Offers practical guidance on recent advances to help in choosing the most appropriate toxicological assay Presents case studies and information on a variety of reference species to help put the ecotoxicological theory into practical risk assess



Marine Ecotoxicology

Marine Ecotoxicology Author Julián Blasco
ISBN-10 9780128033722
Release 2016-08-05
Pages 334
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Marine Ecotoxicology: Current Knowledge and Future Issues is the first unified resource to cover issues related to contamination, responses, and testing techniques of saltwater from a toxicological perspective. With its unprecedented focus on marine environments and logical chapter progression, this book is useful to graduate students, ecotoxicologists, risk assessors, and regulators involved or interested in marine waters. As human interaction with these environments increases, understanding of the pollutants and toxins introduced into the oceans becomes ever more critical, and this book builds a foundation of knowledge to assist scientists in studying, monitoring, and making decisions that affect both marine environments and human health. A team of world renowned experts provide detailed analyses of the most common contaminants in marine environments and explain the design and purpose of toxicity testing methods, while exploring the future of ecotoxicology studies in relation to the world’s oceans. As the threat of increasing pollution in marine environments becomes an ever more tangible reality, Marine Ecotoxicology offers insights and guidance to mitigate that threat. Provides practical tools and methods for assessing and monitoring the accumulation and effects of contaminants in marine environments Unites world renowned experts in marine ecotoxicology to deliver thorough and diverse perspectives Builds the foundation required for risk assessors and regulators to adequately assess and monitor the impact of pollution in marine environments Offers helpful insights and guidance to graduate students, ecotoxicologists, risk assessors, and regulators interested in mitigating threats to marine waters



Molecular markers for tropical trees a practical guide to principles and procedures

Molecular markers for tropical trees  a practical guide to principles and procedures Author
ISBN-10 9789290592259
Release
Pages
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Molecular markers for tropical trees a practical guide to principles and procedures has been writing in one form or another for most of life. You can find so many inspiration from Molecular markers for tropical trees a practical guide to principles and procedures also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Molecular markers for tropical trees a practical guide to principles and procedures book for free.



Biological Effects of Contaminants in Marine Pelagic Ecosystems

Biological Effects of Contaminants in Marine Pelagic Ecosystems Author Ketil Hylland
ISBN-10 UCSD:31822034656652
Release 2006
Pages 475
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Biological Effects of Contaminants in Marine Pelagic Ecosystems has been writing in one form or another for most of life. You can find so many inspiration from Biological Effects of Contaminants in Marine Pelagic Ecosystems also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Biological Effects of Contaminants in Marine Pelagic Ecosystems book for free.



Australian Journal of Chemistry

Australian Journal of Chemistry Author
ISBN-10 CHI:58288612
Release 2002
Pages
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Australian Journal of Chemistry has been writing in one form or another for most of life. You can find so many inspiration from Australian Journal of Chemistry also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Australian Journal of Chemistry book for free.



Slugs snails

Slugs   snails Author Georges Dussart
ISBN-10 CORNELL:31924089457976
Release 2003
Pages 324
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Slugs snails has been writing in one form or another for most of life. You can find so many inspiration from Slugs snails also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Slugs snails book for free.



Environmental Assessment of Estuarine Ecosystems

Environmental Assessment of Estuarine Ecosystems Author Claude Amiard-Triquet
ISBN-10 UCSD:31822037156866
Release 2009-02-11
Pages 355
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With contributions from international experts, this reference covers all aspects of estuaries from the physiological to the economical. Using a comparative case study of two French estuaries, the text demonstrates the state-of-the-art science required to assess the estuary paradox.



Sediment Quality Assessment

Sediment Quality Assessment Author Graeme Batley
ISBN-10 9781486303854
Release 2016-02-01
Pages 360
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Contaminated sediments represent an ongoing threat to the health of aquatic ecosystems. The assessment of sediment quality is, therefore, an important concern for environmental regulators. Sediment quality guidelines are now well established in regulatory frameworks worldwide; however, practical guidance that covers all of the key aspects of sediment quality assessment is not readily available. In 2005, CSIRO published its highly cited Handbook for Sediment Quality Assessment. In the ensuing period, the science has advanced considerably. This practical guide is a revised and much expanded second edition, which will be a valuable tool for environmental practitioners. Written by experts in the field, it provides coverage of: sediment sampling; sample preparation; chemical analysis; ecotoxicology; bioaccumulation; biomarkers; and ecological assessment. In addition, detailed appendices describe protocols for many of the tests to be used.



American Book Publishing Record

American Book Publishing Record Author
ISBN-10 STANFORD:36105111052903
Release 2002
Pages
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American Book Publishing Record has been writing in one form or another for most of life. You can find so many inspiration from American Book Publishing Record also informative, and entertaining. Click DOWNLOAD or Read Online button to get full American Book Publishing Record book for free.



Analysis of Biomarker Data

Analysis of Biomarker Data Author Stephen W. Looney
ISBN-10 9781118552469
Release 2015-01-23
Pages 424
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A “how to” guide for applying statistical methods to biomarker data analysis Presenting a solid foundation for the statistical methods that are used to analyze biomarker data, Analysis of Biomarker Data: A Practical Guide features preferred techniques for biomarker validation. The authors provide descriptions of select elementary statistical methods that are traditionally used to analyze biomarker data with a focus on the proper application of each method, including necessary assumptions, software recommendations, and proper interpretation of computer output. In addition, the book discusses frequently encountered challenges in analyzing biomarker data and how to deal with them, methods for the quality assessment of biomarkers, and biomarker study designs. Covering a broad range of statistical methods that have been used to analyze biomarker data in published research studies, Analysis of Biomarker Data: A Practical Guide also features: A greater emphasis on the application of methods as opposed to the underlying statistical and mathematical theory The use of SAS®, R, and other software throughout to illustrate the presented calculations for each example Numerous exercises based on real-world data as well as solutions to the problems to aid in reader comprehension The principles of good research study design and the methods for assessing the quality of a newly proposed biomarker A companion website that includes a software appendix with multiple types of software and complete data sets from the book’s examples Analysis of Biomarker Data: A Practical Guide is an ideal upper-undergraduate and graduate-level textbook for courses in the biological or environmental sciences. An excellent reference for statisticians who routinely analyze and interpret biomarker data, the book is also useful for researchers who wish to perform their own analyses of biomarker data, such as toxicologists, pharmacologists, epidemiologists, environmental and clinical laboratory scientists, and other professionals in the health and environmental sciences.



Biochemical Ecotoxicology

Biochemical Ecotoxicology Author Francois Gagne
ISBN-10 9780124116238
Release 2014-07-07
Pages 282
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Biochemical Ecotoxicology: Principles and Methods presents practical approaches to biochemical ecotoxicology experiments for environmental protection and conservation. With its methodical, stepped approach this essential reference introduces readers to current techniques for toxicity endpoint testing, suitable for laboratories of any size and budget. Each chapter presents a state-of-the-art principle, a quick and inexpensive procedure (including appropriate reagents), case studies, and demonstrations on how to analyze your results. Generic techniques are covered, suitable for a variety of organisms, as well as high-throughput techniques like quantitative polymerase chain reactions and enzyme-linked immunoassays. Cutting-edge approaches, including gPCR arrays and lipidomic techniques, are also included, making this is an essential reference for anyone who needs to assess environmental toxicity. Practical, cost-effective approaches to assess environmental toxicity endpoints for all types of organism Presents theory, methods, case studies and information on how to analyze results State-of-the-art techniques, such as ‘omics’ approaches to toxicology



Chemical Biomarkers in Aquatic Ecosystems

Chemical Biomarkers in Aquatic Ecosystems Author Thomas S. Bianchi
ISBN-10 1400839106
Release 2011-02-28
Pages 392
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This textbook provides a unique and thorough look at the application of chemical biomarkers to aquatic ecosystems. Defining a chemical biomarker as a compound that can be linked to particular sources of organic matter identified in the sediment record, the book indicates that the application of these biomarkers for an understanding of aquatic ecosystems consists of a biogeochemical approach that has been quite successful but underused. This book offers a wide-ranging guide to the broad diversity of these chemical biomarkers, is the first to be structured around the compounds themselves, and examines them in a connected and comprehensive way. This timely book is appropriate for advanced undergraduate and graduate students seeking training in this area; researchers in biochemistry, organic geochemistry, and biogeochemistry; researchers working on aspects of organic cycling in aquatic ecosystems; and paleoceanographers, petroleum geologists, and ecologists. Provides a guide to the broad diversity of chemical biomarkers in aquatic environments The first textbook to be structured around the compounds themselves Describes the structure, biochemical synthesis, analysis, and reactivity of each class of biomarkers Offers a selection of relevant applications to aquatic systems, including lakes, rivers, estuaries, oceans, and paleoenvironments Demonstrates the utility of using organic molecules as tracers of processes occurring in aquatic ecosystems, both modern and ancient



Clinical Trials

Clinical Trials Author Tom Brody
ISBN-10 9780128042588
Release 2016-02-19
Pages 896
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Clinical Trials, Second Edition, offers those engaged in clinical trial design a valuable and practical guide. This book takes an integrated approach to incorporate biomedical science, laboratory data of human study, endpoint specification, legal and regulatory aspects and much more with the fundamentals of clinical trial design. It provides an overview of the design options along with the specific details of trial design and offers guidance on how to make appropriate choices. Full of numerous examples and now containing actual decisions from FDA reviewers to better inform trial design, the 2nd edition of Clinical Trials is a must-have resource for early and mid-career researchers and clinicians who design and conduct clinical trials. Contains new and fully revised material on key topics such as biostatistics, biomarkers, orphan drugs, biosimilars, drug regulations in Europe, drug safety, regulatory approval and more Extensively covers the "study schema" and related features of study design Incorporates laboratory data from studies on human patients to provide a concrete tool for understanding the concepts in the design and conduct of clinical trials Includes decisions made by FDA reviewers when granting approval of a drug as real world learning examples for readers



Animal Biomarkers as Pollution Indicators

Animal Biomarkers as Pollution Indicators Author David B. Peakall
ISBN-10 9789401123464
Release 2012-12-06
Pages 291
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Ecotoxicology is a relatively new scientific discipline. Indeed, it might be argued that it is only during the last 5-10 years that it has come to merit being regarded as a true science, rather than a collection of procedures for protecting the environment through management and monitoring of pollutant discharges into the environment. The term 'ecotoxicology' was first coined in the late sixties by Prof. Truhaut, a toxicologist who had the vision to recognize the importance of investigating the fate and effects of chemicals in ecosystems. At that time, ecotoxicology was considered a sub-discipline of medical toxicology. Subsequently, several attempts have been made to portray ecotoxicology in a more realistic light. Notably, both F. Moriarty (1988) and F. Ramade (1987) emphasized in their books the broad basis of ecotoxicology, encompassing chemical and radiation effects on all components of ecosystems. In doing so, they and others have shifted concern from direct chemical toxicity to man, to the far more subtle effects that pollutant chemicals exert on natural biota. Such effects potentially threaten the existence of all life on Earth. Although I have identified the sixties as the era when ecotoxicology was first conceived as a coherent subject area, it is important to acknowledge that studies that would now be regarded as ecotoxicological are much older. Wherever people's ingenuity has led them to change the face of nature significantly, it has not escaped them that a number of biological con sequences, often unfavourable, ensue.