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Bioprinting

Bioprinting Author Chee Kai Chua
ISBN-10 9789814612135
Release 2014-11-27
Pages 296
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At labs around the world, researchers have been experimenting with bioprinting, first just to see whether it was possible to push cells through a printhead without killing them (in most cases it is), and then trying to make cartilage, bone, skin, blood vessels, small bits of liver and other tissues. There are other ways to try to “engineer” tissue — one involves creating a scaffold out of plastics or other materials and adding cells to it. In theory, at least, a bioprinter has advantages in manipulating control of the placement of cells and other components to mimic natural structures. But just as the claims made for 3-D printing technology sometimes exceed the reality, the field of bioprinting has seen its share of hype. The reality is that, although bioprinting researchers have made great strides, there are many formidable obstacles to overcome. Nobody who has any credibility claims they can print organs, or believes in their heart of hearts that that will happen in the next 20 years, but for operations like hip replacement, advance in Bio-printing has made customization of certain body parts possible. This book will start from the concept of Tissue Engineering, covering various approaches in Scaffolds for tissue engineering, Bioprinting techniques and Materials for bioprinting, Cell processing, 3D cell culture techniques, Computational design and simulation, multi-disciplinary approaches in bioprinting and finally cover the applications of bioprinting.



3D Printing and Additive Manufacturing

3D Printing and Additive Manufacturing Author Chee Kai Chua
ISBN-10 9789813149281
Release 2016-11-29
Pages 456
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Additive Manufacturing (AM) technologies are developing impressively and are expected to bring about the next revolution. AM is gradually replacing traditional manufacturing methods in some applications because of its unique properties of customisability and versatility. This book provides a very comprehensive and updated text about different types of AM technologies, their respective advantages, shortcomings and potential applications. 3D Printing and Additive Manufacturing: Principles and Applications is a comprehensive textbook that takes readers inside the world of additive manufacturing. This book introduces the different types of AM technologies, categorised by liquid, solid and powder-based AM systems, the common standards, the trends in the field and many more. Easy to understand, this book is a good introduction to anyone interested in obtaining a better understanding of AM. For people working in the industry, this book will provide information on new methods and practices, as well as recent research and development in the field. For professional readers, this book provides a comprehensive guide to distinguish between the different technologies, and will help them make better decisions regarding which technology they should use. For the general public, this book sheds some light on the fast-moving AM field. In this edition, new AM standards (e.g. Standard of Terminology and Classification of AM systems) and format standards will be included, Furthermore, the listing of new machines and systems, materials, and software; as well as new case studies and applications in industries that have recently adopted AM (such as the Marine and Offshore industry) have also been incorporated. Request Inspection Copy



3D Bioprinting

3D Bioprinting Author Ibrahim Tarik Ozbolat
ISBN-10 9780128030301
Release 2016-11-21
Pages 356
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3D Bioprinting: Fundamentals, Principles and Applications provides the latest information on the fundamentals, principles, physics, and applications of 3D bioprinting. It contains descriptions of the various bioprinting processes and technologies used in additive biomanufacturing of tissue constructs, tissues, and organs using living cells. The increasing availability and decreasing costs of 3D printing technologies are driving its use to meet medical needs, and this book provides an overview of these technologies and their integration. Each chapter discusses current limitations on the relevant technology, giving future perspectives. Professor Ozbolat has pulled together expertise from the fields of bioprinting, tissue engineering, tissue fabrication, and 3D printing in his inclusive table of contents. Topics covered include raw materials, processes, machine technology, products, applications, and limitations. The information in this book will help bioengineers, tissue and manufacturing engineers, and medical doctors understand the features of each bioprinting process, as well as bioink and bioprinter types. In addition, the book presents tactics that can be used to select the appropriate process for a given application, such as tissue engineering and regenerative medicine, transplantation, clinics, or pharmaceutics. Describes all aspects of the bioprinting process, from bioink processing through design for bioprinting, bioprinting techniques, bioprinter technologies, organ printing, applications, and future trends Provides a detailed description of each bioprinting technique with an in-depth understanding of its process modeling, underlying physics and characteristics, suitable bioink and cell types printed, and major accomplishments achieved thus far Explains organ printing technology in detail with a step-by-step roadmap for the 3D bioprinting of organs from isolating stem cells to the post-transplantation of organs Presents tactics that can be used to select the appropriate process for a given application, such as tissue engineering and regenerative medicine, transplantation, clinics, or pharmaceutics



Essentials of 3D Biofabrication and Translation

Essentials of 3D Biofabrication and Translation Author Anthony Atala
ISBN-10 9780128010150
Release 2015-07-17
Pages 440
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Essentials of 3D Biofabrication and Translation discusses the techniques that are making bioprinting a viable alternative in regenerative medicine. The book runs the gamut of topics related to the subject, including hydrogels and polymers, nanotechnology, toxicity testing, and drug screening platforms, also introducing current applications in the cardiac, skeletal, and nervous systems, and organ construction. Leaders in clinical medicine and translational science provide a global perspective of the transformative nature of this field, including the use of cells, biomaterials, and macromolecules to create basic building blocks of tissues and organs, all of which are driving the field of biofabrication to transform regenerative medicine. Provides a new and versatile method to fabricating living tissue Discusses future applications for 3D bioprinting technologies, including use in the cardiac, skeletal, and nervous systems, and organ construction Describes current approaches and future challenges for translational science Runs the gamut of topics related to the subject, from hydrogels and polymers to nanotechnology, toxicity testing, and drug screening platforms



3D Bioprinting in Regenerative Engineering

3D Bioprinting in Regenerative Engineering Author Ali Khademhosseini
ISBN-10 9781315280479
Release 2018-04-17
Pages 385
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This book is comprehensive in nature with contributions by leading world experts in 3D bioprinting related to regenerative engineering. It includes history, incorporating the process and methods used in bioprinting. Significant sections will be reserved for the applications of the types of tissues generated by using bioprinting, along with an overview of different technologies used in bioprinting. In addition to equipment, the book also describes the different biomaterials and cells used in these approaches. Overall this is a book that includes both entry-level knowledge and advanced methods and techniques. Applications will emphasize engineering and clinical principles.



Standards Quality Control and Measurement Sciences in 3D Printing and Additive Manufacturing

Standards  Quality Control  and Measurement Sciences in 3D Printing and Additive Manufacturing Author Chee Kai Chua
ISBN-10 9780128134900
Release 2017-06-03
Pages 268
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Standards, Quality Control and Measurement Sciences in 3D Printing and Additive Manufacturing addresses the critical elements of the standards and measurement sciences in 3D printing to help readers design and create safe, reliable products of high quality. With 3D printing revolutionizing the process of manufacturing in a wide range of products, the book takes key features into account, such as design and fabrication and the current state and future potentials and opportunities in the field. In addition, the book provides an in-depth analysis on the importance of standards and measurement sciences. With self-test exercises at the end of each chapter, readers can improve their ability to take up challenges and become proficient in a number of topics related to 3D printing, including software usage, materials specification and benchmarking. Helps the reader understand the quality framework tailored for 3D printing processes Explains data format and process control in 3D printing Provides an overview of different materials and characterization methods Covers benchmarking and metrology for 3D printing



Digital Health

Digital Health Author Homero Rivas
ISBN-10 9783319614465
Release 2018-01-02
Pages 370
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This book presents a comprehensive state-of the-art approach to digital health technologies and practices within the broad confines of healthcare practices. It provides a canvas to discuss emerging digital health solutions, propelled by the ubiquitous availability of miniaturized, personalized devices and affordable, easy to use wearable sensors, and innovative technologies like 3D printing, virtual and augmented reality and driverless robots and vehicles including drones. One of the most significant promises the digital health solutions hold is to keep us healthier for longer, even with limited resources, while truly scaling the delivery of healthcare. Digital Health: Scaling Healthcare to the World addresses the emerging trends and enabling technologies contributing to technological advances in healthcare practice in the 21st Century. These areas include generic topics such as mobile health and telemedicine, as well as specific concepts such as social media for health, wearables and quantified-self trends. Also covered are the psychological models leveraged in design of solutions to persuade us to follow some recommended actions, then the design and educational facets of the proposed innovations, as well as ethics, privacy, security, and liability aspects influencing its acceptance. Furthermore, sections on economic aspects of the proposed innovations are included, analyzing the potential business models and entrepreneurship opportunities in the domain.



Lasers in 3D Printing and Manufacturing

Lasers in 3D Printing and Manufacturing Author Chee Kai Chua
ISBN-10 9789814656443
Release 2016-12-27
Pages 280
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Additive Manufacturing (AM), popularly known as 3D printing, is playing an increasingly significant role in the manufacturing arena. AM has revolutionized how prototypes are to be made and small batch manufacturing should be carried out. Due to high flexibility and high efficiency of lasers, laser-assisted Manufacturing (LAM) and AM technologies are recently getting much attention over traditional methods. This textbook is a timely information resource for undergraduates, postgraduates and researchers who are interested in this emerging technology. The book will cover the basics of lasers, optics and materials used for manufacturing and 3D printing. It will also include several case studies for readers to apply their understanding of the topics, provide sufficient theoretical background and insights to today's key laser-assisted AM processes and conclude with the future prospects of this exciting technology. This is the first textbook tailored specifically for Lasers in 3D Printing and Manufacturing with detailed explanations. The book will focus on laser-assisted 3D printing and Additive Manufacturing (AM) from basic principles of lasers, optics and AM materials to advanced AM technologies, including in-depth discussion on critical aspects throughout the laser-assisted AM processes, such as optical system design, laser-material interaction and laser parameters' optimization. Request Inspection Copy



3D Bioprinting for Reconstructive Surgery

3D Bioprinting for Reconstructive Surgery Author Daniel Thomas
ISBN-10 9780081012161
Release 2017-11-14
Pages 450
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3D Bioprinting for Reconstructive Surgery: Techniques and Applications examines the combined use of materials, procedures and tools necessary for creating structural tissue constructs for reconstructive purposes. Offering a broad analysis of the field, the first set of chapters review the range of biomaterials which can be used to create 3D-printed tissue constructs. Part Two looks at the techniques needed to prepare biomaterials and biological materials for 3D printing, while the final set of chapters examines application-specific examples of tissues formed from 3D printed biomaterials. 3D printing of biomaterials for tissue engineering applications is becoming increasingly popular due to its ability to offer unique, patient-specific parts—on demand—at a relatively low cost. This book is a valuable resource for biomaterials scientists, biomedical engineers, practitioners and students wishing to broaden their knowledge in the allied field. Discusses new possibilities in tissue engineering with 3D printing Presents a comprehensive coverage of the materials, techniques and tools needed for producing bioprinted tissues Reviews emerging technologies in addition to commercial techniques



Organ Printing

Organ Printing Author Dong-Woo Cho
ISBN-10 9781681740799
Release 2015-10-01
Pages 97
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This book introduces various 3D printing systems, biomaterials, and cells for organ printing. In view of the latest applications of several 3D printing systems, their advantages and disadvantages are also discussed. A basic understanding of the entire spectrum of organ printing provides pragmatic insight into the mechanisms, methods, and applications of this discipline. Organ printing is being applied in the tissue engineering field with the purpose of developing tissue/organ constructs for the regeneration of both hard (bone, cartilage, osteochondral) and soft tissues (heart). There are other potential application areas including tissue/organ models, disease/cancer models, and models for physiology and pathology, where in vitro 3D multicellular structures developed by organ printing are valuable.



From Additive Manufacturing to 3D 4D Printing

From Additive Manufacturing to 3D 4D Printing Author Jean-Claude André
ISBN-10 9781119482765
Release 2017-12-27
Pages 468
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With a turnover of some 5-15 billion € / year, the additive manufacturing has industrial niches bearers thanks to processes and materials more and more optimized. While some niches still exist on the application of additive techniques in traditional fields (from jewelery to food for example), several trends emerge, using new concepts: collective production, realization of objects at once (without addition Of material), micro-fluidic, 4D printing exploiting programmable materials and materials, bio-printing, etc. There are both opportunities for new markets, promises not envisaged less than 10 years ago, but difficulties in reaching them.



3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine

3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine Author Lijie Grace Zhang
ISBN-10 9780128006641
Release 2015-01-14
Pages 392
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3D Bioprinting and Nanotechnology in Tissue Engineering provides an in depth introduction to these two technologies and their industrial applications. Stem cells in tissue regeneration are covered, along with nanobiomaterials. Commercialization, legal and regulatory considerations are also discussed in order to help you translate nanotechnology and 3D printing-based products to the marketplace and the clinic. Dr. Zhang’s and Dr. Fishers’ team of expert contributors have pooled their expertise in order to provide a summary of the suitability, sustainability and limitations of each technique for each specific application. The increasing availability and decreasing costs of nanotechnologies and 3D printing technologies are driving their use to meet medical needs, and this book provides an overview of these technologies and their integration. It shows how nanotechnology can increase the clinical efficiency of prosthesis or artificial tissues made by bioprinting or biofabrication. Students and professionals will receive a balanced assessment of relevant technology with theoretical foundation, while still learning about the newest printing techniques. Includes clinical applications, regulatory hurdles, and risk-benefit analysis of each technology. This book will assist you in selecting the best materials and identifying the right parameters for printing, plus incorporate cells and biologically active agents into a printed structure Learn the advantages of integrating 3D printing and nanotechnology in order to improve the safety of your nano-scale materials for biomedical applications



The Golden Ratio and Fibonacci Numbers

The Golden Ratio and Fibonacci Numbers Author Richard A Dunlap
ISBN-10 9789814496940
Release 1997-12-16
Pages 172
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In this invaluable book, the basic mathematical properties of the golden ratio and its occurrence in the dimensions of two- and three-dimensional figures with fivefold symmetry are discussed. In addition, the generation of the Fibonacci series and generalized Fibonacci series and their relationship to the golden ratio are presented. These concepts are applied to algorithms for searching and function minimization. The Fibonacci sequence is viewed as a one-dimensional aperiodic, lattice and these ideas are extended to two- and three-dimensional Penrose tilings and the concept of incommensurate projections. The structural properties of aperiodic crystals and the growth of certain biological organisms are described in terms of Fibonacci sequences. Contents:Basic Properties of the Golden RatioGeometric Problems in Two DimensionsGeometric Problems in Three DimensionsFibonacci NumbersLucas Numbers and Generalized Fibonacci NumbersContinued Fractions and Rational ApproximantsGeneralized Fibonacci Representation TheoremsOptimal Spacing and Search AlgorithmsCommensurate and Incommensurate ProjectionsPenrose TilingsQuasicrystallographyBiological ApplicationsConstruction of the Regular PentagonThe First 100 Fibonacci and Lucas NumbersRelationships Involving the Golden Ratio and Generalized Fibonacci Numbers Readership: Applied mathematicians. keywords:Golden Ratio;Fibonacci Numbers;Number Theory;Quasicrystallography;Tilings;Geometry;Optimization Algorithms;Numerical Sequences;Lucas Numbers;Continued Fractions;Aperiodicity;Incommensurate Structures "This attractive and carefully written book addresses the general reader with interest in mathematics and its application to the physical and biological sciences ... this one will make a valuable addition to academic and personal libraries." The Fibonacci Quarterly



Fabricated

Fabricated Author Hod Lipson
ISBN-10 9781118416945
Release 2013-01-22
Pages 320
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Fabricated tells the story of 3D printers, humble manufacturing machines that are bursting out of the factory and into schools, kitchens, hospitals, even onto the fashion catwalk. Fabricated describes our emerging world of printable products, where people design and 3D print their own creations as easily as they edit an online document. A 3D printer transforms digital information into a physical object by carrying out instructions from an electronic design file, or 'blueprint.' Guided by a design file, a 3D printer lays down layer after layer of a raw material to 'print' out an object. That's not the whole story, however. The magic happens when you plug a 3D printer into today’s mind-boggling digital technologies. Add to that the Internet, tiny, low cost electronic circuitry, radical advances in materials science and biotech and voila! The result is an explosion of technological and social innovation. Fabricated takes the reader onto a rich and fulfilling journey that explores how 3D printing is poised to impact nearly every part of our lives. Aimed at people who enjoy books on business strategy, popular science and novel technology, Fabricated will provide readers with practical and imaginative insights to the question 'how will this technology change my life?' Based on hundreds of hours of research and dozens of interviews with experts from a broad range of industries, Fabricated offers readers an informative, engaging and fast-paced introduction to 3D printing now and in the future.



Rapid Prototyping

Rapid Prototyping Author Chee Kai Chua
ISBN-10 9789814365390
Release 2010-01-14
Pages 540
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Latest Edition: 3D Printing and Additive Manufacturing: Principles and Applications. Fifth Edition of Rapid Prototyping. Rapid prototyping (RP) has revolutionized how prototypes are made and small batch manufacturing is carried out. With rapid prototyping, the strategies used to produce a part change a number of important considerations and limitations previously faced by tool designers and engineers. Now in its third edition, this textbook is still the definitive text on RP. It covers the key RP processes, the available models and specifications, and their principles, materials, advantages and disadvantages. Examples of application areas in design, planning, manufacturing, biomedical engineering, art and architecture are also given. The book includes several related problems so that the reader can test his or her understanding of the topics. New to this edition, the included CD-ROM presents animated illustrations of the working principles of today's key RP processes.



Handbook Of Contemporary Acoustics And Its Applications

Handbook Of Contemporary Acoustics And Its Applications Author Wu Jun-ru
ISBN-10 9789814651301
Release 2016-05-06
Pages 468
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Modern acoustics has blossomed rapidly in the past decades. Beginning as a branch off from the classical physics, modern acoustics has become an interdisciplinary science that has exceeded the boundaries of its origins. As a result, the demand for graduate students, professionals and specialists who need to master the knowledge of acoustics is growing quickly. The primary goal of this publication is to meet this urgent need by providing an updated, comprehensive reference book that educates readers on both fundamental concepts as well as their broader applications in the fast-moving technological world. The Handbook of Contemporary Acoustics and Its Applications systematically covers the theoretical principle and analytical methodology of generation, propagation and reception of acoustic waves in an ideal (inviscid) and non-ideal fluid media. The topics include the transduction, radiation, scattering, diffraction and reception of the acoustic wave. It also discusses the acoustic field in a duct/pipe, waveguide and cavity, the wave propagation in the multi-layers, nonlinear finite amplitude wave propagation and the mechanisms of physical and biological effects and their broad modern applications such as sonoporation, targeted drug delivery, acoustic tweezers, noninvasive high intensity focused ultrasound (HIFU) surgery, as well as sonoluminscence. Readers are also provided with the fundamental mathematic background and relevant references necessary for their creative inventions and applications.This handbook is intended for senior undergraduate and graduate students, as well as specialists working in relevant fields, and may be used as a textbook in courses covering acoustics.



Cell and Organ Printing

Cell and Organ Printing Author Bradley R. Ringeisen
ISBN-10 9048191459
Release 2010-09-02
Pages 260
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Cell and organ printing has become a hot topic of scientific pursuit. Since several early publications between 2000-2003 that demonstrated proof-of-concept, cell and organ printing has blossomed into a rich area for scientific exploration that is being performed by researchers across the globe. Research has thoroughly demonstrated that living cells can be printed via a number of actuations including electrospray, extrusion via micropens and ejection through photothermal, thermal or optical mechanisms. This topic has come of age and it is ripe for exploring the underpinnings of the research to date. We have included research that uses printing technology to deposit or guide cells for tissue engineering applications and for completeness, we have also included chapters describing bacteria printing, biomolecular printing that could be used to build growth factors or recruitment macromolecules into scaffolds, tissue microdissection, as well as live cell printing. The breadth of approaches includes 3D freeform fabrication, ink jet, laser guidance and modified laser direct write techniques. We hope that this book is not the final word but the first word, defining how these tools have been used to take the first steps towards the ultimate goal of creating heterogeneous tissue constructs. Only time will tell whether cell printers will truly become organ printers, but the technologies described in this book hold promise to achieve what the field of regenerative medicine requires - functional 3D scaffolds with multiple cell types differentiated into functional tissue!