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Bioprocess Engineering

Bioprocess Engineering Author Michael L. Shuler
ISBN-10 9780132901413
Release 2017-03-29
Pages 640
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The Leading Introduction to Biochemical and Bioprocess Engineering, Updated with Key Advances in Productivity, Innovation, and Safety Bioprocess Engineering, Third Edition, is an extensive update of the world’s leading introductory textbook on biochemical and bioprocess engineering and reflects key advances in productivity, innovation, and safety. The authors review relevant fundamentals of biochemistry, microbiology, and molecular biology, including enzymes, cell functions and growth, major metabolic pathways, alteration of cellular information, and other key topics. They then introduce evolving biological tools for manipulating cell biology more effectively and to reduce costs of bioprocesses. This edition presents major advances in the production of biologicals; highly productive techniques for making heterologous proteins; new commercial applications for both animal and plant cell cultures; key improvements in recombinant DNA microbe engineering; techniques for more consistent authentic post-translational processing of proteins; and other advanced topics. It includes new, improved, or expanded coverage of The role of small RNAs as regulators Transcription, translation, regulation, and differences between prokaryotes and eukaryotes Cell-free processes, metabolic engineering, and protein engineering Biofuels and energy, including coordinated enzyme systems, mixed-inhibition and enzyme-activation kinetics, and two-phase enzymatic reactions Synthetic biology The growing role of genomics and epigenomics Population balances and the Gompetz equation for batch growth and product formation Microreactors for scale-up/scale-down, including rapid scale-up of vaccine production The development of single-use technology in bioprocesses Stem cell technology and utilization Use of microfabrication, nanobiotechnology, and 3D printing techniques Advances in animal and plant cell biotechnology The text makes extensive use of illustrations, examples, and problems, and contains references for further reading as well as a detailed appendix describing traditional bioprocesses. Register your product at informit.com/register for convenient access to downloads, updates, and corrections as they become available.



Bioprocess Engineering

Bioprocess Engineering Author Michael L. Shuler
ISBN-10 0137062702
Release 2017-03-30
Pages 640
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The Leading Introduction to Biochemical and Bioprocess Engineering, Updated with Key Advances in Productivity, Innovation, and Safety Bioprocess Engineering, Third Edition, is an extensive update of the world's leading introductory textbook on biochemical and bioprocess engineering and reflects key advances in productivity, innovation, and safety. The authors review relevant fundamentals of biochemistry, microbiology, and molecular biology, including enzymes, cell functions and growth, major metabolic pathways, alteration of cellular information, and other key topics. They then introduce evolving biological tools for manipulating cell biology more effectively and to reduce costs of bioprocesses. This edition presents major advances in the production of biologicals; highly productive techniques for making heterologous proteins; new commercial applications for both animal and plant cell cultures; key improvements in recombinant DNA microbe engineering; techniques for more consistent authentic post-translational processing of proteins; and other advanced topics. It includes new, improved, or expanded coverage of The role of small RNAs as regulators Transcription, translation, regulation, and differences between prokaryotes and eukaryotes Cell-free processes, metabolic engineering, and protein engineering Biofuels and energy, including coordinated enzyme systems, mixed-inhibition and enzyme-activation kinetics, and two-phase enzymatic reactions Synthetic biology The growing role of genomics and epigenomics Population balances and the Gompetz equation for batch growth and product formation Microreactors for scale-up/scale-down, including rapid scale-up of vaccine production The development of single-use technology in bioprocesses Stem cell technology and utilization Use of microfabrication, nanobiotechnology, and 3D printing techniques Advances in animal and plant cell biotechnology The text makes extensive use of illustrations, examples, and problems, and contains references for further reading as well as a detailed appendix describing traditional bioprocesses.



Bioprocess Engineering

Bioprocess Engineering Author Michael L. Shuler
ISBN-10 1292025999
Release 2014
Pages 542
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For Senior-level and graduate courses in Biochemical Engineering, and for programs in Agricultural and Biological Engineering or Bioengineering. This concise yet comprehensive text introduces the essential concepts of bioprocessing-internal structure and functions of different types of microorganisms, major metabolic pathways, enzymes, microbial genetics, kinetics and stoichiometry of growth and product information-to traditional chemical engineers and those in related disciplines. It explores the engineering principles necessary for bioprocess synthesis and design, and illustrates the application of these principles to modern biotechnology for production of pharmaceuticals and biologics, solution of environmental problems, production of commodities, and medical applications.



Bioprocess Engineering

Bioprocess Engineering Author Shijie Liu
ISBN-10 9780444637932
Release 2016-08-29
Pages 1172
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Bioprocess Engineering: Kinetics, Sustainability, and Reactor Design, Second Edition, provides a comprehensive resource on bioprocess kinetics, bioprocess systems, sustainability, and reaction engineering. Author Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering, also introducing key principles that enable bioprocess engineers to engage in analysis, optimization, and design with consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme in this book, with more advanced techniques and applications being covered in depth. This updated edition reflects advances that are transforming the field, ranging from genetic sequencing, to new techniques for producing proteins from recombinant DNA, and from green chemistry, to process stability and sustainability. The book introduces techniques with broad applications, including the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities, medical applications, such as tissue engineering and gene therapy, and solving critical environmental problems. Includes the mechanistic description of biotransformations and chemical transformations Provides quantitative descriptions of bioprocesses Contains extensive illustrative drawings, which make the understanding of the subject easy Includes bioprocess kinetics and reactor analysis Contains examples of the various process parameters, their significance, and their specific practical use Incorporates sustainability concepts into the various bioprocesses



Bioprocess Engineering Principles

Bioprocess Engineering Principles Author Pauline M. Doran
ISBN-10 9780122208515
Release 2013
Pages 919
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This welcome new edition covers bioprocess engineering principles for the reader with a limited engineering background. It explains process analysis from an engineering point of view, using worked examples and problems that relate to biological systems. Application of engineering concepts is illustrated in areas of modern biotechnology such as recombinant protein production, bioremediation, biofuels, drug development, and tissue engineering, as well as microbial fermentation. The main sub-disciplines within the engineering curriculum are all covered; Material and Energy Balances, Transport Processes, Reactions and Reactor Engineering. With new and expanded material, Doran's textbook remains the book of choice for students seeking to move into bioprocess engineering. NEW TO THIS EDITION: All chapters thoroughly revised for current developments, with over 200 pgs of new material, including significant new content in: Metabolic Engineering Sustainable Bioprocessing Membrane Filtration Turbulence and Impeller Design Downstream Processing Oxygen Transfer Systems Over 150 new problems and worked examples More than 100 new illustrations New to this edition: All chapters thoroughly revised for current developments, with over 200 pgs of new material, including significant new content in: Metabolic Engineering Sustainable Bioprocessing Membrane Filtration Turbulence and Impeller Design Downstream Processing Oxygen Transfer Systems Over 150 new problems and worked examples More than 100 new illustrations



Biochemical Engineering Second Edition

Biochemical Engineering  Second Edition Author Douglas S. Clark
ISBN-10 0824789490
Release 1995-10-26
Pages 702
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This work provides comprehensive coverage of modern biochemical engineering, detailing the basic concepts underlying the behaviour of bioprocesses as well as advances in bioprocess and biochemical engineering science. It includes discussions of topics such as enzyme kinetics and biocatalysis, microbial growth and product formation, bioreactor design, transport in bioreactors, bioproduct recovery and bioprocess economics and design. A solutions manual is available to instructors only.



Biochemical Engineering

Biochemical Engineering Author Shigeo Katoh
ISBN-10 9783527685011
Release 2015-02-02
Pages 328
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Completely revised, updated, and enlarged, this second edition now contains a subchapter on biorecognition assays, plus a chapter on bioprocess control added by the new co-author Jun-ichi Horiuchi, who is one of the leading experts in the field. The central theme of the textbook remains the application of chemical engineering principles to biological processes in general, demonstrating how a chemical engineer would address and solve problems. To create a logical and clear structure, the book is divided into three parts. The first deals with the basic concepts and principles of chemical engineering and can be read by those students with no prior knowledge of chemical engineering. The second part focuses on process aspects, such as heat and mass transfer, bioreactors, and separation methods. Finally, the third section describes practical aspects, including medical device production, downstream operations, and fermenter engineering. More than 40 exemplary solved exercises facilitate understanding of the complex engineering background, while self-study is supported by the inclusion of over 80 exercises at the end of each chapter, which are supplemented by the corresponding solutions. An excellent, comprehensive introduction to the principles of biochemical engineering.



Problem Solving in Chemical and Biochemical Engineering with POLYMATH Excel and MATLAB

Problem Solving in Chemical and Biochemical Engineering with POLYMATH  Excel  and MATLAB Author Michael B. Cutlip
ISBN-10 0131482041
Release 2008
Pages 727
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Problem Solving in Chemical and Biochemical Engineering with POLYMATH™, Excel, and MATLAB®, Second Edition , is a valuable resource and companion that integrates the use of numerical problem solving in the three most widely used software packages: POLYMATH, Microsoft Excel, and MATLAB. Recently developed POLYMATH capabilities allow the automatic creation of Excel spreadsheets and the generation of MATLAB code for problem solutions. Students and professional engineers will appreciate the ease with which problems can be entered into POLYMATH and then solved independently in all three software packages, while taking full advantage of the unique capabilities within each package. The book includes more than 170 problems requiring numerical solutions. This greatly expanded and revised second edition includes new chapters on getting started with and using Excel and MATLAB. It also places special emphasis on biochemical engineering with a major chapter on the subject and with the integration of biochemical problems throughout the book. General Topics and Subject Areas, Organized by Chapter Introduction to Problem Solving with Mathematical Software Packages Basic Principles and Calculations Regression and Correlation of Data Introduction to Problem Solving with Excel Introduction to Problem Solving with MATLAB Advanced Problem-Solving Techniques Thermodynamics Fluid Mechanics Heat Transfer Mass Transfer Chemical Reaction Engineering Phase Equilibrium and Distillation Process Dynamics and Control Biochemical Engineering Practical Aspects of Problem-Solving Capabilities Simultaneous Linear Equations Simultaneous Nonlinear Equations Linear, Multiple Linear, and Nonlinear Regressions with Statistical Analyses Partial Differential Equations (Using the Numerical Method of Lines) Curve Fitting by Polynomials with Statistical Analysis Simultaneous Ordinary Differential Equations (Including Problems Involving Stiff Systems, Differential-Algebraic Equations, and Parameter Estimation in Systems of Ordinary Differential Equations) The Book's Web Site (http://www.problemsolvingbook.com) Provides solved and partially solved problem files for all three software packages, plus additional materials Describes discounted purchase options for educational version of POLYMATH available to book purchasers Includes detailed, selected problem solutions in Maple™, Mathcad®, and Mathematica™



Bioseparations Science and Engineering

Bioseparations Science and Engineering Author Roger G. Harrison
ISBN-10 9780190213732
Release 2015-01-27
Pages 432
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Designed for undergraduates, graduate students, and industry practitioners, Bioseparations Science and Engineering fills a critical need in the field of bioseparations. Current, comprehensive, and concise, it covers bioseparations unit operations in unprecedented depth. In each of the chapters, the authors use a consistent method of explaining unit operations, starting with a qualitative description noting the significance and general application of the unit operation. They then illustrate the scientific application of the operation, develop the required mathematical theory, and finally, describe the applications of the theory in engineering practice, with an emphasis on design and scaleup. Unique to this text is a chapter dedicated to bioseparations process design and economics, in which a process simular, SuperPro Designer? is used to analyze and evaluate the production of three important biological products. New to this second edition are updated discussions of moment analysis, computer simulation, membrane chromatography, and evaporation, among others, as well as revised problem sets. Unique features include basic information about bioproducts and engineering analysis and a chapter with bioseparations laboratory exercises. Bioseparations Science and Engineering is ideal for students and professionals working in or studying bioseparations, and is the premier text in the field.



An Introduction to Metabolic and Cellular Engineering

An Introduction to Metabolic and Cellular Engineering Author S Cortassa
ISBN-10 9789814489515
Release 2002-03-07
Pages 264
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Metabolic and cellular engineering, as presented in this book, is a powerful alliance of two technologies: genetics–molecular biology and fermentation technology. Both are driven by continuous refinement of the basic understanding of metabolism, physiology and cellular biology (growth, division, differentiation), as well as the development of new mathematical modeling techniques. The authors' approach is original in that it integrates several disciplines into a coordinated scheme, i.e. microbial physiology and bioenergetics, thermodynamics and enzyme kinetics, biomathematics and biochemistry, genetics and molecular biology. Thus, it is called a transdisciplinary approach (TDA). The TDA provides the basis for the rational design of microorganisms or cells in a way that has rarely been utilized to its full extent. Contents:Matter and Energy BalancesCell Growth and Metabolite Production. Basic ConceptsMethods of Quantitation of Cellular “Processes Performance”Dynamic Aspects of Bioprocess BehaviorBioprocess Development with Plant CellsCellular Engineering Readership: Undergraduates, graduates and researchers in biomedical engineering, biochemistry and biotechnology. Keywords:Reviews:“The book provides very well selected examples that permit an easy comprehension of the achievements expected from the different techniques. I consider the book suitable for both experimentalists and theoreticians … it also provides an excellent selection of key references on the main techniques available in the field which are very useful for students and research workers.”Marta Cascante Serratosa Professor of Biochemistry and Molecular Biology University of Barcelona “A worked example towards the end of the book of the use of such a scheme was most welcome. The book is aimed at final year undergraduates and postgraduate researchers and is suitable for personal purchase.”Microbiology Today



Biorenewable Resources

Biorenewable Resources Author Robert C. Brown
ISBN-10 9781118524923
Release 2013-12-06
Pages 388
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Biorenewable Resources: Engineering New Products from Agriculture, 2nd Edition will provide comprehensive coverage of engineering systems that convert agricultural crops and residues into bioenergy and biobased products. This edition is thoroughly updated and revised to better serve the needs of the professional and research fields working with biorenewable resource development and production. Biorenewable resources is a rapidly growing field that forms at the interface between agricultural and plant sciences and process engineering. Biorenewable Resources will be an indispensable reference for anyone working in the production of biomass or biorenewable resources.



Protein Chromatography

Protein Chromatography Author Giorgio Carta
ISBN-10 9783527318193
Release 2010-06-15
Pages 364
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With its focus on process development and large-scale bioseparation tasks, this is tailor-made reading for the professional bioengineer in both the biotech and pharmaceutical industries. Following a tried-and-tested concept, this guide has been developed over several years in training courses for biotech and chemical engineers in Europe and the U.S. The first part deals with the theory, introducing chromatography and its dynamics, as well as discussing mass transfer and dispersion effects. The second part then goes on to cover equipment and protocols, determining the retention factor and HETP from isocratic and elution experiments, as well as the mass transfer and intraparticle diffusivity from batch and shallow-bed adsorption experiments.



Bioreaction Engineering Principles

Bioreaction Engineering Principles Author Jens Nielsen
ISBN-10 9781461507673
Release 2012-12-06
Pages 528
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This is the second edition of the text "Bioreaction Engineering Principles" by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990's will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of "modem" biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of "real" bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter.



Biochemical Engineering and Biotechnology

Biochemical Engineering and Biotechnology Author Ghasem Najafpour
ISBN-10 9780444633774
Release 2015-02-24
Pages 668
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Biochemical Engineering and Biotechnology, 2nd Edition, outlines the principles of biochemical processes and explains their use in the manufacturing of every day products. The author uses a diirect approach that should be very useful for students in following the concepts and practical applications. This book is unique in having many solved problems, case studies, examples and demonstrations of detailed experiments, with simple design equations and required calculations. Covers major concepts of biochemical engineering and biotechnology, including applications in bioprocesses, fermentation technologies, enzymatic processes, and membrane separations, amongst others Accessible to chemical engineering students who need to both learn, and apply, biological knowledge in engineering principals Includes solved problems, examples, and demonstrations of detailed experiments with simple design equations and all required calculations Offers many graphs that present actual experimental data, figures, and tables, along with explanations



Metabolic Engineering

Metabolic Engineering Author Jens Nielsen
ISBN-10 9783540418481
Release 2001-09-11
Pages 183
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With contributions by numerous experts



Analysis Synthesis and Design of Chemical Processes

Analysis  Synthesis and Design of Chemical Processes Author Richard Turton
ISBN-10 9780132459181
Release 2008-12-24
Pages 1088
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The Leading Integrated Chemical Process Design Guide: Now with New Problems, New Projects, and More More than ever, effective design is the focal point of sound chemical engineering. Analysis, Synthesis, and Design of Chemical Processes, Third Edition, presents design as a creative process that integrates both the big picture and the small details–and knows which to stress when, and why. Realistic from start to finish, this book moves readers beyond classroom exercises into open-ended, real-world process problem solving. The authors introduce integrated techniques for every facet of the discipline, from finance to operations, new plant design to existing process optimization. This fully updated Third Edition presents entirely new problems at the end of every chapter. It also adds extensive coverage of batch process design, including realistic examples of equipment sizing for batch sequencing; batch scheduling for multi-product plants; improving production via intermediate storage and parallel equipment; and new optimization techniques specifically for batch processes. Coverage includes Conceptualizing and analyzing chemical processes: flow diagrams, tracing, process conditions, and more Chemical process economics: analyzing capital and manufacturing costs, and predicting or assessing profitability Synthesizing and optimizing chemical processing: experience-based principles, BFD/PFD, simulations, and more Analyzing process performance via I/O models, performance curves, and other tools Process troubleshooting and “debottlenecking” Chemical engineering design and society: ethics, professionalism, health, safety, and new “green engineering” techniques Participating successfully in chemical engineering design teams Analysis, Synthesis, and Design of Chemical Processes, Third Edition, draws on nearly 35 years of innovative chemical engineering instruction at West Virginia University. It includes suggested curricula for both single-semester and year-long design courses; case studies and design projects with practical applications; and appendixes with current equipment cost data and preliminary design information for eleven chemical processes–including seven brand new to this edition.



Electrochemical Engineering Principles

Electrochemical Engineering Principles Author Geoffrey Prentice
ISBN-10 0132490382
Release 1991
Pages 296
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Electrochemical Engineering Principles has been writing in one form or another for most of life. You can find so many inspiration from Electrochemical Engineering Principles also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Electrochemical Engineering Principles book for free.