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Chronic Inflammation

Chronic Inflammation Author Sashwati Roy
ISBN-10 9781439872116
Release 2012-09-17
Pages 472
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Although acute inflammation is a healthy physiological response indicative of wound healing, chronic inflammation has been directly implicated in a wide range of degenerative human health disorders encompassing almost all present day non-communicable diseases including autoimmune diseases, obesity, diabetes and atherosclerosis. Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions provides an exposition of the process of chronic inflammation in three parts: Systems Biology of Inflammation and Regulatory Mechanisms describes the process of chronic inflammation including initiation, progression, and resolution. Pathologies Associated with Inflammation gives a rigorous and critical treatment of specific human health disorders where chronic inflammation plays a major role. Nutrition & Therapeutics for Inflammatory Diseases details the protective abilities of structurally diverse antioxidants, phytochemicals, anti-inflammatory diets, omega-3 fatty acids, NSAIDs, disease modifying anti-rheumatic drugs, and novel regimens. Designed for scientists as well as clinicians, Chronic Inflammation provides critical understanding of the key checkpoints that regulate chronic inflammation. Going beyond the epidemiology of chronic inflammation, the text covers regulatory mechanisms controlling inflammation initiation, progression, and resolution. The authors address pathologies associated with inflammation and provide various nutritional and therapeutic interventions for inflammatory diseases.



Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome

Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome Author Debasis Bagchi
ISBN-10 9780128120088
Release 2018-05-25
Pages 554
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Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome, Second Edition, provides an overview of the current diabetes epidemic, outlines the consequences of this crisis, and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. Contributing experts provide up-to-date global approaches to the critical consequences of metabolic syndrome and make the book an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes. Completely revised with 15 new chapters, the book includes coverage of the roles of gut microbiome in obesity and diabetes, macrovascular and microvascular complications, diabetes, metabolic syndrome and kidney disease, aspects of diabetic cardiomyopathy, diabetes, Alzheimer’s and neurodegenerative diseases, roles of SGLT2 inhibitors in the treatment of type 2 diabetes, novel biomarkers in diabetes, roles of Trigonella foenum-graecumseed extract in type 2 diabetes, beneficial effects of chromium (III) and vanadium supplements in diabetes, prevention of type 1 diabetes, novel drugs in the therapeutic intervention of type 2 diabetes, eHealth and mobile apps for self-management, artificial pancreatic transplantation, non-invasive glucose monitoring, and the app for glucose regulation. Contains a scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndrome Includes coverage of Pre-diabetes conditions, plus both Type I and Type II Diabetes Presents both prevention and treatment options



Biomarkers of Cardiometabolic Risk Inflammation and Disease

Biomarkers of Cardiometabolic Risk  Inflammation and Disease Author Filipe Palavra
ISBN-10 9783319160184
Release 2015-04-11
Pages 165
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This book discusses recent advances in the area of cardiometabolic risk biomarkers of chronic inflammatory and cardiovascular disorders. Tackling the topic in a systematic manner, the book starts with an introduction to cardiometabolic risk and its clinical relevance, comparing emergent and classical biomarkers. It then goes on to discuss cardiometabolic risk biomarkers in a range of diseases, including diabetes, ischemic stroke and neurodegenerative disorders. Biomarkers of Cardiometabolic Risk, Inflammation and Disease is aimed at doctors specializing in internal medicine, neurology, cardiology, rheumatology, nephrology or endocrinology and will also be of interest to GPs, trainee doctors and clinical and basic researchers working on cardiovascular and autoimmune disorders.



Lipid Oxidation in Health and Disease

Lipid Oxidation in Health and Disease Author Corinne M. Spickett
ISBN-10 9781482202861
Release 2015-03-03
Pages 440
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Oxidative modification of lipids and phospholipids—including radical damage, halogenation, and nitration—result in significant changes to the chemical properties of the molecules, which in turn have a major effect on their biochemical functions. Lipid oxidation has long been regarded as a deleterious process responsible for lipid rancidity, loss of function, and generation of toxic products. However in recent years, research has also focused on the non-detrimental physiological and pathological effects of these chemical reactions. Lipid Oxidation in Health and Disease provides an up-to-date review of the role of oxidized lipid products in physiological and pathophysiological processes. Covering the diverse topics that contribute to research in this important field, this book explores: The mechanisms of lipid oxidation, both enzymatic and non-enzymatic Antioxidant defenses and lipid oxidation Lipid oxidation products and cell signaling The roles of oxidized lipids in specific diseases—including cardiovascular, neurodegenerative, and metabolic disorders, as well as in cancer Drug targeting and the therapeutic potential of oxidized lipids Accurate measurement of the formation of lipid oxidation products and investigation of their biological effects and roles in disease are critical to biomedical science and new targeted therapeutics. Written by acknowledged experts in the field, this book provides a broad survey of both established knowledge and recent findings on the action of oxidized lipid products on cell signaling and gene expression in health and disease.



Psoriasis and Psoriatic Arthritis

Psoriasis and Psoriatic Arthritis Author Siba P. Raychaudhuri
ISBN-10 9781351648950
Release 2017-12-15
Pages 348
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Psoriasis is a life-long chronic autoimmune disease characterized by thick scaly skin lesions and often associated with severe arthritis. Chronic psoriasis is connected to health conditions such as psoriatic arthritis, inflammatory disorders, type 2 diabetes, and cardiovascular disease.



Cardiovascular Diseases

Cardiovascular Diseases Author Nilanjana Maulik, Ph.D.
ISBN-10 9781439882016
Release 2013-04-09
Pages 614
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With cardiovascular disease remaining one of the primary causes of morbidity and mortality worldwide, there is a great need to further understand the molecular basis of this disease class and develop new therapeutic or preventative measures. Cardiovascular Diseases: Nutritional and Therapeutic Interventions presents up-to-date information on the pathobiology of cardiovascular diseases, emphasizing emerging therapeutics and nutritional interventions. The book is divided into four parts: epidemiology, epigenetics, pathobiology, and therapies for cardiovascular diseases. Part I details epidemiological studies, highlighting the extent of the clinical problem. Part II describes the genetic and, primarily, epigenetic modifications associated with cardiovascular disease, including the importance of DNA methylation status and the possibility of early intervention using simple dietary modifications. The text also discusses histone modifications associated with disease and potential therapeutic synthetic and dietary compounds such as resveratrol and garlic. Covering the etiology and pathobiology, part III discusses lipid regulation, micro-RNAs, emerging cell-based therapies, and new receptor targets for therapeutics as well as targeted imaging. It also describes the link between cancer therapies and cardiomyopathy and the potential of vitamin C to ameliorate this effect. Part IV focuses on therapeutic and nutritional interventions, namely, stem cell therapies, emerging nanomedicines, and a wide range of dietary interventions. These include general healthy diets, fruits and vegetables, botanicals, effects of specific compounds such as antioxidants, and discussions on garlic, curcumin, and resveratrol. The text also covers lifestyle factors, emphasizing the importance of stress in the occurrence of and meditation and yoga in the management of cardiovascular disease. This book provides a comprehensive reference for clinicians and scientists, combining epidemiology, prevention, and modern treatment strategies.



Clinical Naturopathy

Clinical Naturopathy Author Jon Wardle
ISBN-10 9780729579261
Release 2010-07-29
Pages 850
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A landmark guide to naturopathic practice in Australia – ideal for naturopaths, naturopathy students and Allied Health and medical practitioners Clinical Naturopathy: An evidence-based guide to practice details key treatment protocols and evidence-based complementary medicine interventions for use in naturopathic practice. This valuable naturopathy resource is authored by leading practitioners in the field. Its unique perspective combines clinical experience with evidence-based substantiation from rigorous medical research. Clinical Naturopathy explores key naturopathic treatments – including herbal treatments, nutritional and dietary treatments and lifestyle treatments – for common medical symptoms and conditions encountered in modern practice. Clinical Naturopathy: An evidence-based guide to practice outlines an introduction to case-taking methodology and naturopathic diagnostic techniques. It then details treatment protocols and naturopathic prescriptions to treat major health conditions within individual body systems. The textbook also offers special sections on naturopathic treatment throughout the life cycle, including paediatrics, pregnancy and aging, as well as complex health conditions like HIV, cancer and pain management. Comprehensive appendices provide additional clinically important material, such as reference levels for laboratory medical tests, nutrient food values and traditional Chinese medical diagnosis. This one-of-a-kind naturopathic reference makes essential reading for practitioners wishing to enhance practical application of their skills in a clinical setting, and advance their knowledge of evidence-based complementary medicine interventions. • addresses pre-clinical and clinical naturopathy subjects (from third year naturopathy to post-graduate level) • focuses on major medical conditions, and outlines naturopathic and integrative medical treatments • features case studies to contextualise theory into relevant clinical application • includes user-friendly clinical decision trees, tables and figures • is rigorously researched with over 4000 references



Rheumatology E Book

Rheumatology E Book Author Marc C. Hochberg
ISBN-10 9780702063039
Release 2014-06-24
Pages 2112
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Stay current in the ever-changing discipline of rheumatology with clear, reliable guidance from Hochberg’s Rheumatology, one of the most respected and trusted sources in the field. Designed to meet the needs of the practicing clinician, this medical reference book provides extensive, authoritative coverage of rheumatic diseases from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Track disease progression and treat patients more effectively with the information on genetic findings, imaging outcomes, cell and biologic therapies, rheumatoid arthritis, and SLE. Incorporate recent findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics. Remain up to date on the latest information in rheumatology through 13 brand-new chapters covering biomedical and translation science, disease and outcome assessment, new imaging modalities, early emerging disease, clinical therapeutics, patient management, and rehabilitation. Take advantage of expanded coverage of small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. Focus on the core knowledge needed for successful results with each chapter co-authored by an internationally-renowned specialist in the field. Easily find the information you need thanks to a consistent, user-friendly format with templated content and large-scale images.



The Macrophage as Therapeutic Target

The Macrophage as Therapeutic Target Author Siamon Gordon
ISBN-10 9783642557422
Release 2012-12-06
Pages 496
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During the past decade, the rapid growth of molecular and cellular knowledge of macrophages, as a specialized host defense and homeostatic system, has begun to offer attractive targets for therapeutic intervention. Macrophages play a central role in a wide range of disease processes, from genetically determined lysosomal storage diseases, to acute sepsis, chronic inflammation and repair, tissue injury and cell death. Under- or overactivity of macrophage clearance, immune effector functions and responses to metabolic abnormalities contribute to common disorders such as autoimmunity, atherosclerosis, Alzheimer’s disease and major infections including AIDS and Tuberculosis. Whilst the goals of therapeutic intervention based on improved understanding of macrophage functions and their contribution to pathogenesis may seem self evident, there are considerable difficulties in producing useful new agents. The present volume covers a range of subjects and provides opportunities for a more focused macrophage-targeted approach. The individual chapters review selected topics briefly, to place cellular processes and molecular targets in perspective. Overall, the volume should provide a broad sample of the state of the art. Useful reviews and references in the literature are cited within individual chapters.



COPD An Issue of Clinics in Chest Medicine

COPD  An Issue of Clinics in Chest Medicine Author Peter J Barnes
ISBN-10 9780323260916
Release 2014-02-15
Pages 294
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This issue of Clinics in Chest Medicine is Guest Edited by Peter J. Barnes FRS, FMedSci from Imperial College London and will fosus on COPD. Article topics include epidemiology, pathophysiology, cellular and molecular mechanisms and comorbidities of COPD, diagnosis and phenotype of COPD, pulmonary rehabilitation, asthma and COPD, biomarkers, bronchodilators, non invasive ventialtion, and new drug therapies.



Retina E Book

Retina E Book Author Stephen J. Ryan
ISBN-10 9781455737802
Release 2012-11-01
Pages 2564
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Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today’s new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard. Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia, and the Americas. Make the best use of new technologies with expanded and updated coverage of optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging. Apply the latest knowledge on anti-VEGF therapy for age related macular degeneration, diabetic retinopathy and vein disease. Learn about artificial vision, drug delivery to the posterior segment, advances in macular surgery, vitrectomy, and complex retinal detachment, with updates on tumors, retinal genetics, cell biology, important basic science topics, and much more. Get the most out of new pharmacologic approaches in the management of age-related macular degeneration and diabetic retinopathy. In your practice, diagnostic evaluations, and now even treatments, will be influenced by recent scientific discoveries such as in the areas of nanotechnology, neuro protection, stem cells and gene therapy, among other scientific contributions. View videos of surgical procedures and access the complete contents of Retina, 5th Edition online at www.expertconsult.com, fully searchable, with regular updates and a downloadable image gallery.



European Heart Journal Supplements

European Heart Journal Supplements Author
ISBN-10 UCLA:L0082059999
Release 2001
Pages
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European Heart Journal Supplements has been writing in one form or another for most of life. You can find so many inspiration from European Heart Journal Supplements also informative, and entertaining. Click DOWNLOAD or Read Online button to get full European Heart Journal Supplements book for free.



Obesity

Obesity Author Debasis Bagchi
ISBN-10 9781439854266
Release 2012-07-06
Pages 1008
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The World Health Organization (WHO) has declared obesity a global epidemic. Its prevalence has more than doubled since 1980, causing a myriad of health problems for children and adults. Obesity: Epidemiology, Pathophysiology, and Prevention, Second Edition explores the molecular mechanisms and pathophysiology leading to obesity and metabolic disorders. It examines the safety of obesity drugs and drug development strategies as well as the role of physical activity, nutrition, and nutraceutical supplements in obesity treatment and prevention. With contributions from a cadre of internationally known experts, the book covers a spectrum of essential topics related to this widespread phenomenon, including: The relationship between obesity and type 2 diabetes The addiction mechanism related to refined foods as a significant factor in obesity The correlation between obesity and environmental estrogens, endocrine disruption, cigarette smoking, and inflammatory response The role of drug and chemical toxicities and genomic imprinting disorders in obesity The safety and regulation of prescription and over-the-counter weight loss drugs Various diets, the glycemic index, and the role of exercise in treating or preventing obesity Controversy over effective vs. banned weight loss supplements Childhood obesity and its prevention Bariatric surgery for weight management and reversal of metabolic disorders As the public has become more aware of the deadly adverse effects of obesity, numerous products and programs have targeted the overweight and obese population, many with dangerous side effects. It is essential that we develop strategic, therapeutic intervention supported by credible data. This volume is an ideal reference point for researchers looking for new avenues of inquiry and practicing medical professionals, clinical nutritionists, and dietitians seeking guidance for their patients.



Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease Author Derek Chadwick
ISBN-10 UOM:39015049723151
Release 2001
Pages 286
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Chronic obstructive pulmonary disease (COPD) is the most common respiratory disorder of adults in the developed world and is the fourth main cause of death in the USA. It is also associated with high morbidity, and poses an enormous burden of suffering and expense. Despite this, the disease has received little attention compared with other respiratory conditions such as asthma and lung cancer. Current treatment can offer some marginal symptomatic relief but does not address the underlying disease process. Indeed, smoking cessation is the only intervention known to alter the rate of disease progression. There is clearly great need, and potential, for the development of superior therapies for symptomatic relief and disease modification. This book brings together leading researchers and physicians to discuss the most recent advances in our understanding of COPD, and draws together basic and clinical aspects relevant to the topic. Coverage includes the basic pathology, current and potential therapies, and detailed consideration of the major theories for the pathogenesis of COPD.



NIH almanac 2002

NIH almanac 2002 Author
ISBN-10 STANFORD:24504248920
Release 2003
Pages
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NIH almanac 2002 has been writing in one form or another for most of life. You can find so many inspiration from NIH almanac 2002 also informative, and entertaining. Click DOWNLOAD or Read Online button to get full NIH almanac 2002 book for free.



Psychiatry

Psychiatry Author Allan Tasman
ISBN-10 9781118753361
Release 2015-02-05
Pages 2768
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Now in a new Fourth Edition, Psychiatry remains the leading reference on all aspects of the current practice and latest developments in psychiatry. From an international team of recognised expert editors and contributors, Psychiatry provides a truly comprehensive overview of the entire field of psychiatry in 132 chapters across two volumes. It includes two new sections, on psychosomatic medicine and collaborative care, and on emergency psychiatry, and compares Diagnostic and Statistical Manual (DSM-5) and International Classification of Diseases (ICD10) classifications for every psychiatric disorder. Psychiatry, Fourth Edition is an essential reference for psychiatrists in clinical practice and clinical research, residents in training, and for all those involved in the treatment psychiatric disorders. Includes a a companion website at www.tasmanpsychiatry.com featuring PDFs of each chapter and downloadable images



Directory of Biomedical and Health Care Grants

Directory of Biomedical and Health Care Grants Author Grants Program
ISBN-10 1573565997
Release 2005
Pages 644
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Grants are supposed to enable work, not create more of it. You need a guide, a map, and the right tools for the job. Helping you from your earliest brainstorms to fully funded projects, this essential directory offers countless tips and resources for anyone seeking funding for research, faculty development, dissertations, internships, scholarships and assistantships, facility and organizational support, conferences, and more. This latest edition covers over 2,300 funding sources from all levels of government, corporations, and foundations. Each record includes: BL Grant title BL Description BL Requirements BL Amount BL Application deadline BL Contact information (phone, fax, and email) BL Internet access BL Sponsor name and address BL Samples of awarded grants (when available) Four indexes--subject, sponsoring organization, program type, and geographic--help you identify the right program quickly. Also included is "A Guide to Proposal Planning and Writing," by Jeremy Miner and Lynn Miner, which offers essential tips on the grantseeking process.