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Clinical Applications of Botulinum Neurotoxin

Clinical Applications of Botulinum Neurotoxin Author Keith Alan Foster
ISBN-10 9781493902613
Release 2014-07-08
Pages 196
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Currently, there are tremendous advances being made in understanding the basic science of both the structure and function of botulinum neurotoxins. This knowledge is opening up opportunities in regard to both therapeutic uses and treatment and protection options for civil and bio-defense applications. This volume fully evaluates the status of neurotoxin research and exploitation. The book is a multi-authored collection of chapters written by the leading authorities responsible for the current scientific and clinical research that is advancing the understanding and exploitation of the neurotoxins and is both up to date and authoritative.



Molecular Aspects of Botulinum Neurotoxin

Molecular Aspects of Botulinum Neurotoxin Author Keith A. Foster
ISBN-10 9781461494546
Release 2014-07-08
Pages 345
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Currently, there are tremendous advances being made in understanding the basic science of both the structure and function of botulinum neurotoxins. This knowledge is opening up opportunities in regard to both therapeutic uses and treatment and protection options for civil and bio-defense applications. This volume fully evaluates the status of neurotoxin research and exploitation with a focus on clinical application. The book is a multi-authored collection of chapters written by the leading authorities responsible for the current scientific and clinical research that is advancing the understanding and exploitation of the neurotoxins and is both up to date and authoritative.



The Comprehensive Sourcebook of Bacterial Protein Toxins

The Comprehensive Sourcebook of Bacterial Protein Toxins Author Joseph E. Alouf
ISBN-10 9780128005897
Release 2015-05-29
Pages 1200
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The Comprehensive Sourcebook of Bacterial Protein Toxins 4th Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content. Descriptions of relevant toxins as well as representative toxins of the main bacterial toxin families to allow for a better comparison between them. Focused chapters on toxin applications and common properties or general features of toxins.



Clinical Uses of Botulinum Toxins

Clinical Uses of Botulinum Toxins Author Anthony B. Ward
ISBN-10 9781139461665
Release 2007-03-22
Pages
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Botulinum toxins now play a very significant role in the management of a wide variety of medical conditions; from headaches to hypersalivation, and from spasticity to sweating. In this book, a strong, international team of experts outline the basic neurochemistry of botulinum toxins and chart the progress of the drug from laboratory to clinic. Then individual chapters summarize their use for the main clinical indications in the context of other available treatments. This book will be of interest to neuroscientists and practising clinicians working in a wide range of specialities, from neurology and dermatology to pediatrics, plastic surgery and rehabilitation medicine.



Practical Periodontal Plastic Surgery

Practical Periodontal Plastic Surgery Author Serge Dibart
ISBN-10 9781118985489
Release 2017-02-07
Pages 176
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Practical Periodontal Plastic Surgery, Second Edition builds on the success of the first edition to provide the qualified and trainee periodontist with an essential guide to the clinical requirements and step-by-step procedures of periodontal plastic surgery. Features additional clinical photographs to illustrate procedures Brings together periodontal and plastic surgery expertise Retains the popular step-by-step format for quick and clear reference



Botulinum Neurotoxins

Botulinum Neurotoxins Author Andreas Rummel
ISBN-10 9783642335709
Release 2012-12-14
Pages 324
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The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application.



Veterinary Toxicology

Veterinary Toxicology Author Ramesh C. Gupta
ISBN-10 9780128114117
Release 2018-02-06
Pages 1238
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Veterinary Toxicology, Basic and Clinical Principles, Third Edition, is a unique, single reference that teaches the basic principles of veterinary toxicology to any student at the DVM, MS or PhD level. While comparable texts are primarily directed on the field of human toxicology, this text thoroughly prepares toxicologists and students on the newest approaches for diagnosing chemical and plant poisoning cases in animals. Many chapters on topics not covered in any previous books are provided, such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology. Completely revised and updated to include the most recent developments in the field, including new toxins, methods and regions, this book is an essential resource for advanced students and researchers in toxicology, practicing veterinary toxicologists, poison control centers, marine biologists, environmentalists and animal scientists. Provides a complete, up-to-date, integrated source of information on toxins and poisons relating to animals Covers all important aspects of veterinary toxicology with completely updated and revised chapters Includes basic principles of a key toxicology concept, along with clinical applications and a list of major references for further reading



Handbook of Toxicology of Chemical Warfare Agents

Handbook of Toxicology of Chemical Warfare Agents Author Ramesh C. Gupta
ISBN-10 9780128004944
Release 2015-01-21
Pages 1198
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Handbook of Toxicology of Chemical Warfare Agents, Second Edition covers every aspect of deadly toxic chemicals used in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this essential reference offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors and biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, and countermeasures. Expanding on the ground-breaking first edition, Handbook of Toxicology of Chemical Warfare Agents has been completely updated, presenting the most recent advances in field. Brand new chapters include a case study of the Iran-Iraq war, an overview of chemical weapons of mass destruction, explosives, ricin, the human respiratory system, alternative testing methods, brain injuries, and more. Unites world-leading experts to present cutting-edge, agent-specific information on chemical warfare agents and their adverse effects on human and animal health and the environment. Covers all aspects of chemical warfare agent modes of action, detection, prevention, therapeutic treatment and countermeasures. Features a full update on the first edition to reflect the most recent advances in the field as well as nine new chapters.



Easy Injections

Easy Injections Author Lyn D. Weiss
ISBN-10 9780750675277
Release 2007
Pages 210
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This practical, one-of-a-kind manual guides you step by step through the most common injection techniques for a full range of disorders. Experts in the field help you assess whether an injection is indicated, localize the site, choose the correct needle, avoid possible complications, provide necessary post-injection care, and more. A user-friendly format, clinical pearls, state-of-the-art line drawings, and the latest guidelines make this handbook an essential reference for any physician performing an injection procedure. A uniform format guides you through every step of the most common injection techniques, from treating musculoskeletal and neurologic disorders to performing alternative procedures such as acupuncture. Recommendations for the most effective number of injections, as well as what medications and how much to inject, help you stay up to date and provide state-of-the-art care. Extensive coverage of common principles specific to each injection area helps you conquer even your toughest cases. Clinical pearls in each chapter provide easy access to key concepts and techniques. Detailed line drawings highlighting major landmarks paired with photographs provide vivid, visual guidance for accurate needle placement. A handy, portable size makes need-to-know information accessible at any time.



Handbook of Botulinum Toxins for Aesthetic Indications

Handbook of Botulinum Toxins for Aesthetic Indications Author Kenneth Beer
ISBN-10 9781909836006
Release 2015-10-24
Pages 168
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Botox continues to be the number one cosmetic procedure performed worldwide. Physicians from a wide range of specialties – not just dermatologists but also OBGYNs, primary care practitioners and ophthalmologists – are eager to learn from results-focused educational material written by leading practitioners. Most botox books focus solely on injection technique. Handbook of Botulinum Toxins for Aesthetic Indications: Theory and Practice describes current techniques, but focuses on securing optimum results in different patient types, e.g. patients of different ethnicities, patients with thick skin, heavy brows, and so on. In addition, the book covers hot topics such as the use of new types of neurotoxins, the problem of counterfeit products, and combining neurotoxins with other modalities such as fillers and lasers. Edited by a recognized educator in this area, and taking a unique problem-based approach, Handbook of Botulinum Toxins for Aesthetic Indications gives practical guidance on the use of different strategies in different patient types to ensure the best possible aesthetic results. Unique, practical emphasis on treatment strategies for different patient types Includes coverage of new neurotoxins recently approved for use Highly illustrated with colour photographs and detailed drawings showing injection sites and technique Written by well-known educators in dermatologic surgery



War Neurology

War Neurology Author L. Tatu
ISBN-10 9783318056068
Release 2016-04-04
Pages 244
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Interest in the history of neurological science has increased significantly during the last decade, but the significance of war has been overlooked in related research. In contrast, this book highlights war as a factor of progress in neurological science. Light is shed on this little-known topic through accounts given by neurologists in war, experiences of soldiers suffering from neurological diseases, and chapters dedicated to neurology in total and contemporary war. Written by experts, the contributions in this book focus on the Napoleonic Wars, the American Civil War, the Franco-Prussian War of 1870, World Wars I and II, and recent conflicts such as Vietnam or Afghanistan. Comprehensive yet concise and accessible, this book serves as a fascinating read for neurologists, neurosurgeons, psychiatrists, historians, and anyone else interested in the history of neurology.



Therapy with Botulinum Toxin

Therapy with Botulinum Toxin Author Joseph Jankovic
ISBN-10 0824788249
Release 1994-02-01
Pages 638
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This comprehensive reference details new developments in the field of neurotoxins and the clinical use of botulinum toxin (BTX)-reviewing the biology, pharmacology, immunology, physiology, production, mechanisms of action, and methods of administration of BTX.



Botox Nation

Botox Nation Author Dana Berkowitz
ISBN-10 9781479825264
Release 2017-01-10
Pages 256
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The American Society for Aesthetic Plastic Surgery estimates there are about two-and-a-half million Botox procedures performed annually, and that number continues to increase. The procedure is used as a preventive measure against aging and a means by which bodies, particularly women’s, can be transformed and “improved” through the appearance of youth. But why is Botox so popular, and why is aging such a terrifying concept? Botox Nation draws from engaging, in-depth interviews with Botox users and providers as well as Dana Berkowitz’s own experiences receiving the injections. The interviews reveal the personal motivations for using Botox and help unpack how anti-aging practices are conceived by, and resonate with, everyday people. Berkowitz is particularly interested in how Botox is now being targeted to younger women; since Botox is a procedure that must be continually administered to work, the strategic choice to market to younger women, Berkowitz argues, aims to create lifetime consumers. Berkowitz also analyzes magazine articles, advertisements, and even medical documents to consider how narratives of aging are depicted. She employs a critical feminist lens to consider the construction of feminine bodies and selves, and explores the impact of cosmetic medical interventions aimed at maintaining the desired appearance of youth, the culture of preventative medicine, the application of medical procedures to seemingly healthy bodies, and the growth and technological advancement to the anti-aging industry. The first in-depth social investigation into the development of Botox as a phenomenon, Botox Nation is a captivating and critical story of how norms about bodies, gender, and aging are constructed and reproduced on both cultural and individual levels.



Botulinum Toxin in Clinical Dermatology

Botulinum Toxin in Clinical Dermatology Author Anthony V. Benedetto
ISBN-10 9780203495056
Release 2006-01-13
Pages 326
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Botulinum Toxin in Clinical Dermatology explores botulinum toxin, from its early recognition as a food borne toxin to its current form as a pharmaceutical injectible. This high quality, well-illustrated, practical manual presents the latest on the clinical use of the different types of botulinum toxins available and presents in a clear and concise way all the pertinent and up-to-date information on how to inject botulinum toxin and avoid complications. Packed with clinical photographs and scientific drawings, each chapter addresses a different aspect of the topic. This is the most comprehensive and authoritative reference for cosmetic injections of botulinum toxin for removal of facial and neck wrinkles.



Botulinum Toxin Treatment of Pain Disorders

Botulinum Toxin Treatment of Pain Disorders Author Bahman Jabbari
ISBN-10 9781493925018
Release 2015-03-23
Pages 246
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This book provides an authoritative overview of botulinum neurotoxin (BoNT) treatment menus for 14 pain categories with an evidence based literature review on each pain disorder, illustrative figures along with brief video clips showing the techniques and patient interviews. Introductory chapters cover basic information about the mechanism, function and the analgesic effects of the BoNTs based on the data derived from animal studies. Clinical chapters define pain in conditions such as post-herpetic and post-traumatic neuralgias, plantar fasciitis, low back pain, post-surgical pain syndromes and migraine in detail, provide discussion of current modes of treatment and updated information on BoNT therapy. Each chapter also includes illustrative case histories. Botulinum Toxin Treatment of Pain Disorders will prove an invaluable resource for clinicians and researchers involved in the treatment of pain disorders including neurologists, pain medicine specialists, anesthesiologists, internists, those conducting research in pharmacology and toxicology as well as students in these areas.



Medical Toxicology of Natural Substances

Medical Toxicology of Natural Substances Author Donald G. Barceloux
ISBN-10 9781118382769
Release 2012-03-07
Pages 1184
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Interest and information in the field of medical toxicology has grown rapidly, but there has never been a concise, authoritative reference focused on the subjects of natural substances, chemical and physical toxins, drugs of abuse, and pharmaceutical overdoses. Medical Toxicology of Natural Substances finally gives you an easily accessible resource for vital toxicological information on foods, plants, and animals in key areas in the natural environment.



Digital PCR

Digital PCR Author George Karlin-Neumann
ISBN-10 1493977768
Release 2018-05-01
Pages 557
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This volume explores and explains how digital PCRs (dPCRs) help in the study of numerous topics, such as infectious diseases, evolution of cancer and treatment responses, somatic mosaicism, genome editing and cell therapy, and food testing for GMOs and pathogens. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Digital PCR: Methods and Protocols is a valuable resource for specialists in various fields, including geneticists, neurologists, immunologists, oncologists, and researchers who are interested in environmental sciences.”