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Computational Cardiovascular Mechanics

Computational Cardiovascular Mechanics Author Julius M. Guccione
ISBN-10 1441907300
Release 2010-01-08
Pages 320
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Computational Cardiovascular Mechanics provides a cohesive guide to creating mathematical models for the mechanics of diseased hearts to simulate the effects of current treatments for heart failure. Clearly organized in a two part structure, this volume discusses various areas of computational modeling of cardiovascular mechanics (finite element modeling of ventricular mechanics, fluid dynamics) in addition to a description an analysis of the current applications used (solid FE modeling, CFD). Edited by experts in the field, researchers involved with biomedical and mechanical engineering will find Computational Cardiovascular Mechanics a valuable reference.



Computational Cardiovascular Mechanics

Computational Cardiovascular Mechanics Author Julius M. Guccione
ISBN-10 1489985050
Release 2014-11-26
Pages 320
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Computational Cardiovascular Mechanics provides a cohesive guide to creating mathematical models for the mechanics of diseased hearts to simulate the effects of current treatments for heart failure. Clearly organized in a two part structure, this volume discusses various areas of computational modeling of cardiovascular mechanics (finite element modeling of ventricular mechanics, fluid dynamics) in addition to a description an analysis of the current applications used (solid FE modeling, CFD). Edited by experts in the field, researchers involved with biomedical and mechanical engineering will find Computational Cardiovascular Mechanics a valuable reference.



Biomechanics

Biomechanics Author Manuel Doblare
ISBN-10 9781780210230
Release 2015-12-30
Pages 498
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Biomechanics is a component of Encyclopedia of Physical Sciences, Engineering and Technology Resources in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. The enormous progress in the field of health sciences that has been achieved in the 19th and 20th centuries would have not been possible without the enabling interaction and support of sophisticated technologies that progressively gave rise to a new interdisciplinary field named alternatively as bioengineering or biomedical engineering. Although both terms are synonymous, the latter is less general since it limits the field of application to medicine and clinical practice, while the former covers semantically the whole field of interaction between life sciences and engineering, thus including also applications in biology, biochemistry or the many '-omics'. We use in this book the second, with more general meaning, recalling the very important relation between fundamental science and engineering. And this also recognizes the tremendous economic and social impacts of direct application of engineering in medicine that maintains the health industry as one with the fastest growth in the world economy. Biomechanics, in particular, aims to explain and predict the mechanics of the different components of living beings, from molecules to organisms as well as to design, manufacture and use of any artificial device that interacts with the mechanics of living beings. It helps, therefore, to understand how living systems move, to characterize the interaction between forces and deformation along all spatial scales, to analyze the interaction between structural behavior and microstructure, with the very important particularity of dealing with adaptive systems, able to adapt their internal structure, size and geometry to the particular mechanical environment in which they develop their activity, to understand and predict alterations in the mechanical function due to injuries, diseases or pathologies and, finally, to propose methods of artificial intervention for functional diagnosis or recovery. Biomechanics is today a very highly interdisciplinary subject that attracts the attention of engineers, mathematicians, physicists, chemists, material specialists, biologists, medical doctors, etc. They work in many different topics from a purely scientific objective to industrial applications and with an increasing arsenal of sophisticated modeling and experimental tools but always with the final objectives of better understanding the fundamentals of life and improve the quality of life of human beings. One purpose in this volume has been to present an overview of some of these many possible subjects in a self-contained way for a general audience. This volume is aimed at the following major target audiences: University and College Students, Educators, Professional Practitioners, and Research Personnel.



Computational Modeling in Biomechanics

Computational Modeling in Biomechanics Author Suvranu De
ISBN-10 9048135753
Release 2010-03-10
Pages 581
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Availability of advanced computational technology has fundamentally altered the investigative paradigm in the field of biomechanics. Armed with sophisticated computational tools, researchers are seeking answers to fundamental questions by exploring complex biomechanical phenomena at the molecular, cellular, tissue and organ levels. The computational armamentarium includes such diverse tools as the ab initio quantum mechanical and molecular dynamics methods at the atomistic scales and the finite element, boundary element, meshfree as well as immersed boundary and lattice-Boltzmann methods at the continuum scales. Multiscale methods that link various scales are also being developed. While most applications require forward analysis, e.g., finding deformations and stresses as a result of loading, others involve determination of constitutive parameters based on tissue imaging and inverse analysis. This book provides a glimpse of the diverse and important roles that modern computational technology is playing in various areas of biomechanics including biofluids and mass transfer, cardiovascular mechanics, musculoskeletal mechanics, soft tissue mechanics, and biomolecular mechanics.



Clinical Cardiac MRI

Clinical Cardiac MRI Author Jan Bogaert
ISBN-10 9783642230356
Release 2012-02-04
Pages 709
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Clinical Cardiac MRI is a comprehensive textbook intended for everyone involved in magnetic resonance imaging of the heart. It is designed both as a useful guide for newcomers to the field and as an aid for those who routinely perform such studies. The first edition, published in 2004-5, was very well received within the cardiac imaging community, and has generally been considered the reference because of its completeness, its clarity, and the number and quality of the illustrations. Moreover, the addition of a CD-ROM showing 50 real-life cases significantly enhanced the value of the book. In this second edition, the aim has been to maintain the same quality while incorporating the newest insights and developments in this rapidly evolving domain of medical imaging. The four editors, all experts in the field, have taken great care to ensure a homogeneous high standard throughout the book. Finally, the selection of 100 real-life cases, added as online material, will further enhance the value of this textbook.



Heart Mechanics

Heart Mechanics Author El-Sayed H. Ibrahim
ISBN-10 9781351645379
Release 2017-09-19
Pages 597
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MRI techniques have been recently introduced for non-invasive qualification of regional myocardial mechanics, which is not achievable with other imaging modalities. Covering more than twenty-three years of developments in MRI techniques for accessing heart mechanics, this book provides a plethora of techniques and concepts that assist readers choose the best technique for their purpose. It reviews research studies and clinical trials that implemented MRI techniques for studying heart mechanics.



Computational Cardiology

Computational Cardiology Author Frank B. Sachse
ISBN-10 9783540259268
Release 2005-01-12
Pages 330
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Computational Cardiology has been writing in one form or another for most of life. You can find so many inspiration from Computational Cardiology also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Computational Cardiology book for free.



Computational Modeling of Objects Presented in Images Fundamentals Methods and Applications

Computational Modeling of Objects Presented in Images  Fundamentals  Methods  and Applications Author Yongjie Jessica Zhang
ISBN-10 9783319099941
Release 2014-07-23
Pages 414
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This book constitutes the refereed proceedings of the 4th International Conference on Computational Modeling of Objects Presented in Images, CompIMAGE 2014, held in Pittsburgh, PA, USA, in September 2014. The 29 revised full papers presented together with 10 short papers and 6 keynote talks were carefully reviewed and selected from 54 submissions. The papers cover the following topics: medical treatment, imaging and analysis; image registration, denoising and feature identification; image segmentation; shape analysis, meshing and graphs; medical image processing and simulations; image recognition, reconstruction and predictive modeling; image-based modeling and simulations; and computer vision and data-driven investigations.



Patient Specific Modeling of the Cardiovascular System

Patient Specific Modeling of the Cardiovascular System Author Roy C.P. Kerckhoffs
ISBN-10 1441966919
Release 2010-09-03
Pages 240
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Peter Hunter Computational physiology for the cardiovascular system is entering a new and exciting phase of clinical application. Biophysically based models of the human heart and circulation, based on patient-specific anatomy but also informed by po- lation atlases and incorporating a great deal of mechanistic understanding at the cell, tissue, and organ levels, offer the prospect of evidence-based diagnosis and treatment of cardiovascular disease. The clinical value of patient-specific modeling is well illustrated in application areas where model-based interpretation of clinical images allows a more precise analysis of disease processes than can otherwise be achieved. For example, Chap. 6 in this volume, by Speelman et al. , deals with the very difficult problem of trying to predict whether and when an abdominal aortic aneurysm might burst. This requires automated segmentation of the vascular geometry from magnetic re- nance images and finite element analysis of wall stress using large deformation elasticity theory applied to the geometric model created from the segmentation. The time-varying normal and shear stress acting on the arterial wall is estimated from the arterial pressure and flow distributions. Thrombus formation is identified as a potentially important contributor to changed material properties of the arterial wall. Understanding how the wall adapts and remodels its material properties in the face of changes in both the stress loading and blood constituents associated with infl- matory processes (IL6, CRP, MMPs, etc.



Ventricular Mechanics in Congenital Heart Disease

Ventricular Mechanics in Congenital Heart Disease Author Giovanni Biglino
ISBN-10 9782889452644
Release 2017-08-29
Pages
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Looking at "Horse in Motion", the iconic photograph by E. Muybridge, it is almost possible to hear the horse galloping. The pounding sound of the hoofs hitting the ground -like a drum- can also echo the rythmic beating of the human heart. That sound, that visceral rhythm, reminds us of the link between motion and performance: the perfectly executed stride of the horse, the incredible coordination of multiscale phenomena behind a heart beat. Furthermore, the decomposed sequence in Muybridge's photograph has become a well-known example of breaking motion into its components over time, and as such is reminiscent of those images that are routinely acquired in clinical practice, where the heart appears dilating and shirnking in a sequence of snapshots. The investigation of this motion and its subtleties is essential for refining our understanding of cardiac function, and the appreciation of how and when this motion is no longer perfectly executed can lead us to understand functional impairments and provide insight into the unfolding of pathology. In the presence of congenital heart disease (CHD), cardiac mechanics are altered: from single ventricle physiology to conduction abnormalities to different cardiomyopathies, it is important to both capture and interpret biomechanical changes that occur in the presence of a congenital defect. This special issue in Frontiers in Pediatrics, now an e-book, focuses on 'Ventricular mechanics in congenital heart disease' and looks at current knowledge of phenomena such as systolic/diastolic dysfuction and current methods (chiefly in cardiovascular magnetic resonance imaging and echocardiography) to evaluate cardiac function in the presence of CHD, and then presents a series of original studies that employ both medical imaging and computational modelling techniques to study specific CHD scenarios.



Biomechanics of Living Organs

Biomechanics of Living Organs Author Yohan Payan
ISBN-10 9780128040607
Release 2017-05-01
Pages 400
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Biomechanics of Living Organs: Hyperelastic Constitutive Laws for Finite Element Modeling is the first book to cover finite element biomechanical modeling of each organ in the human body. This collection of chapters from the leaders in the field focuses on the constitutive laws for each organ. Each author introduces the state-of-the-art concerning constitutive laws and then illustrates the implementation of such laws with Finite Element Modeling of these organs. The focus of each chapter is on instruction, careful derivation and presentation of formulae, and methods. When modeling tissues, this book will help users determine modeling parameters and the variability for particular populations. Chapters highlight important experimental techniques needed to inform, motivate, and validate the choice of strain energy function or the constitutive model. Remodeling, growth, and damage are all covered, as is the relationship of constitutive relationships of organs to tissue and molecular scale properties (as net organ behavior depends fundamentally on its sub components). This book is intended for professionals, academics, and students in tissue and continuum biomechanics. Covers hyper elastic frameworks for large tissue deformations Considers which strain energy functions are the most appropriate to model the passive and active states of living tissue Evaluates the physical meaning of proposed energy functions



Biomechanics of Soft Tissue in Cardiovascular Systems

Biomechanics of Soft Tissue in Cardiovascular Systems Author Gerhard A. Holzapfel
ISBN-10 9783709127360
Release 2014-05-04
Pages 342
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The book is written by leading experts in the field presenting an up-to-date view of the subject matter in a didactically sound manner. It presents a review of the current knowledge of the behaviour of soft tissues in the cardiovascular system under mechanical loads, and the importance of constitutive laws in understanding the underlying mechanics is highlighted. Cells are also described together with arteries, tendons and ligaments, heart, and other biological tissues of current research interest in biomechanics. This includes experimental, continuum mechanical and computational perspectives, with the emphasis on nonlinear behaviour, and the simulation of mechanical procedures such as balloon angioplasty.



Advances in Cardiovascular Physiological Phenomena Research and Application 2012 Edition

Advances in Cardiovascular Physiological Phenomena Research and Application  2012 Edition Author
ISBN-10 9781481643245
Release 2012-12-26
Pages 16
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Advances in Cardiovascular Physiological Phenomena Research and Application / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Cardiovascular Physiological Phenomena in a compact format. The editors have built Advances in Cardiovascular Physiological Phenomena Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cardiovascular Physiological Phenomena in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Cardiovascular Physiological Phenomena Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.



Mechanical Circulatory and Respiratory Support

Mechanical Circulatory and Respiratory Support Author Shaun Gregory
ISBN-10 9780128104927
Release 2017-09-19
Pages 852
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Mechanical Circulatory and Respiratory Support is a comprehensive overview of the past, present and future development of mechanical circulatory and respiratory support devices. Content from over 60 internationally-renowned experts focusses on the entire life-cycle of mechanical circulatory and respiratory support – from the descent into heart and lung failure, alternative medical management, device options, device design, implantation techniques, complications and medical management of the supported patient, patient-device interactions, cost effectiveness, route to market and a view to the future. This book is written as a useful resource for biomedical engineers and clinicians who are designing new mechanical circulatory or respiratory support devices, while also providing a comprehensive guide of the entire field for those who are already familiar with some areas and want to learn more. Reviews of the most cutting-edge research are provided throughout each chapter, along with guides on how to design new devices and which areas require specific focus for future research and development. Covers a variety of disciplines, from anatomy of organs and evolution of cardiovascular devices, to their clinical applications and the manufacturing and marketing of devices Provides engineering and clinical perspectives to assist readers in the design of a market appropriate device Discusses history, design, usage, and development of mechanical circulatory and respiratory support systems



Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes

Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes Author Miguel Cerrolaza
ISBN-10 9780128117194
Release 2017-10-17
Pages 454
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Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes covers new and exciting modeling methods to help bioengineers tackle problems for which the Finite Element Method is not appropriate. The book covers a wide range of important subjects in the field of numerical methods applied to biomechanics, including bone biomechanics, tissue and cell mechanics, 3D printing, computer assisted surgery and fluid dynamics. Modeling strategies, technology and approaches are continuously evolving as the knowledge of biological processes increases. Both theory and applications are covered, making this an ideal book for researchers, students and R&D professionals. Provides non-conventional analysis methods for modeling Covers the Discrete Element Method (DEM), Particle Methods (PM), MessLess and MeshFree Methods (MLMF), Agent-Based Methods (ABM), Lattice-Boltzmann Methods (LBM) and Boundary Integral Methods (BIM) Includes contributions from several world renowned experts in their fields Compares pros and cons of each method to help you decide which method is most applicable to solving specific problems



Cardiology Science and Technology

Cardiology Science and Technology Author Dhanjoo N. Ghista
ISBN-10 9781420088076
Release 2016-04-27
Pages 531
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Cardiology Science and Technology comprehensively deals with the science and biomedical engineering formulations of cardiology. As a textbook, it addresses the teaching, research, and clinical aspects of cardiovascular medical engineering and computational cardiology. The books consists of two sections. The first section deals with left ventricular (LV) wall stress, cardiac contractility, ventricular remodeling, active wall stress and systolic pressure generation, and vector cardiogram characteristics, with applications in cardiology. The second section covers ECG signal analysis for arrhythmias detection, LV pumping (intra-LV, aortic and coronary flow) characteristics, and coronary bypass surgery design, with applications in cardiology and cardiac surgery. This book is like an exciting train ride through the heart and into blood flows within its chamber, the coronary tree, the aorta, and finally into coronary flow and bypass grafting. The train starts from the heart’s central station and journeys through exciting places of heart wall stresses, cardiac contractility measures to characterize heart failure, and active stress generation to develop systolic heart pressure. We learn about cardiomyopathic heart remodeling and its surgical ventricular restoration, theory of ECG and vector cardiogram with medical applications, and heart rate variability signal processing to detect cardiac arrhythmias. In the heart chamber, we witness the amazing intricate intra-ventricular flow patterns. Then, we study pressure pulse wave propagation into the aorta, determination of pulse wave velocity and arterial elasticity as a measure of arteriosclerosis. We climb into the mountainous coronary terrain and look at the fascinating scenery of coronary flows and myocardial perfusion that governs cardiac contractility. Finally, we arrive at coronary bypass grafting and witness the new sequential anastomosis design for enhanced patency. This fascinating journey helps us to fully appreciate cardiology from the science, technology, engineering, and mathematics viewpoint. The book represents what can be termed as computational cardiology, and hence belongs to the emerging field of computational medicine.



Emerging Trends in Applications and Infrastructures for Computational Biology Bioinformatics and Systems Biology

Emerging Trends in Applications and Infrastructures for Computational Biology  Bioinformatics  and Systems Biology Author Hamid R Arabnia
ISBN-10 9780128042595
Release 2016-03-25
Pages 592
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Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology: Systems and Applications covers the latest trends in the field with special emphasis on their applications. The first part covers the major areas of computational biology, development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques for the study of biological and behavioral systems. The second part covers bioinformatics, an interdisciplinary field concerned with methods for storing, retrieving, organizing, and analyzing biological data. The book also explores the software tools used to generate useful biological knowledge. The third part, on systems biology, explores how to obtain, integrate, and analyze complex datasets from multiple experimental sources using interdisciplinary tools and techniques, with the final section focusing on big data and the collection of datasets so large and complex that it becomes difficult to process using conventional database management systems or traditional data processing applications. Explores all the latest advances in this fast-developing field from an applied perspective Provides the only coherent and comprehensive treatment of the subject available Covers the algorithm development, software design, and database applications that have been developed to foster research