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Development of the Ocular Lens

Development of the Ocular Lens Author Frank J. Lovicu
ISBN-10 0521838193
Release 2004-09-15
Pages 398
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This book provides a comprehensive view of research in lens developmental biology, emphasising technical and molecular breakthroughs. Elucidation of the mechanisms that govern lens development has enabled us to understand how the normal lens forms and how developmental processes are involved in the maintenance of its normal structure, function and growth throughout life. This knowledge is fundamental to our understanding of many lens disorders. The ocular lens has also become a model for understanding the developmental biology of more complex organ systems. In this 2004 book, leading experts in lens cell biology and development discuss lens evolution, induction, morphology, the regulation of the lens cell cycle and fiber cell differentiation, as well as lens regeneration. This book is an authoritative treatment of the subject that will serve as a reference for graduate students and research scientists in developmental biology and in the visual sciences, as well as for ophthalmologists.



Development of the Visual System

Development of the Visual System Author S.P. Bhat
ISBN-10 9783805578714
Release 2004-01-01
Pages 182
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All the tissues of the eye, including the lens, the cornea, the ciliary body, the neuroretina and the retinal pigment epithelium must work in harmony for the realization of clear vision.The phenotypic emergence of each of these tissues requires intercellular communication, which is achieved through direct physical contact as well as through diffusion and reception of the molecular beacons.This volume provides an overview of the molecular and cellular biology of eye development and encompasses themes like early gene expression in the surface ectoderm and the optic cup, retinal neurogenesis, signaling molecules and axonal guidance. It presents new findings on the influence of the lens on the development of the visual system and how gene expression in the optic cup controls differentiation of the lens fiber cell while established ideas about the morphogenesis of the ciliary body are challenged. A valuable source of information for developmental biologists and neurobiologists as well as ophthalmologists interested in understanding the relationship between temporally and spatially regulated gene activity and function and cellular interactions in early development and neuronal functions.



Regulation of Mouse Lens Development by Fibroblast Growth Factor Signaling

Regulation of Mouse Lens Development by Fibroblast Growth Factor Signaling Author Craig Michael Stolen
ISBN-10 WISC:89071164628
Release 1999
Pages 400
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Regulation of Mouse Lens Development by Fibroblast Growth Factor Signaling has been writing in one form or another for most of life. You can find so many inspiration from Regulation of Mouse Lens Development by Fibroblast Growth Factor Signaling also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Regulation of Mouse Lens Development by Fibroblast Growth Factor Signaling book for free.



Animal Models in Eye Research

Animal Models in Eye Research Author
ISBN-10 0080921035
Release 2011-04-28
Pages 232
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The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease. * Presents information on the major animal models used in eye research including invertebrates and vertebrates * Provides researchers with information needed to choose between model organisms * Includes an introductory chapter on the different types of eyes, stressing possible common molecular machinery



The Ocular Lens

The Ocular Lens Author Harry Maisel
ISBN-10 0824772970
Release 1985
Pages 479
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The Ocular Lens has been writing in one form or another for most of life. You can find so many inspiration from The Ocular Lens also informative, and entertaining. Click DOWNLOAD or Read Online button to get full The Ocular Lens book for free.



Ocular Theraputics and Drug Delivery

Ocular Theraputics and Drug Delivery Author Indra K. Reddy
ISBN-10 1566762138
Release 1995-12-12
Pages 587
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Since ocular therapeutics and drug delivery is a subject of interest to specialists from various disciplines such as chemical, biochemical, medical, pharmaceutical, and toxicological, it truly presents a unique situation requiring a multi-disciplinary approach in understanding and addressing various problems. Yet we see that scientists associated with these areas are working, by and large, independently of one another, thus limiting dissemination of knowledge, experience and ideas that would greatly enhance the overall progress in this area of research. Regrettably, the information currently available in ocular therapeutics and drug delivery, though extensive, is still fragmented into various disciplines making meaningful synthesis difficult. Several books are available that cover one or two aspects of the multi-disciplinary fields on an individual basis; however, none is available that covers all of them. The chapters contained in this book are specific to various interrelated areas of ocular therapeutics and drug delivery and are written by acknowledged experts from both academia and industry. The book itself is divided into five parts, namely: (I) overview,basic principles, and methodology; (II) pathopharmacology and clinical applications; (III) chemical/ biochemical approaches to ocular drug delivery; (IV) formulation and drug delivery considerations; and (V) industrial and regulatory considerations. Individual chapters in each section, apart from presenting a concise text, entail an extensive listing of references.



A Clinical Handbook on Child Development Paediatrics E Book

A Clinical Handbook on Child Development Paediatrics   E Book Author Sandra Johnson
ISBN-10 9780729580892
Release 2012-10-31
Pages 320
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This handbook offers a succinct study of Childhood Development Paediatrics with practical applications for helping the child and family through all areas of the developmental process. The book covers diverse topics like developmental delay, learning difficulties, attention deficit disorders, autism, Asperger syndrome, behaviour difficulties, language disorders, school refusal, bullying, emotional difficulties, neurological impairments that affect development (examples being cerebral palsy and brain injury) and motor coordination problems. It also offers online case scenarios on autism, ADHD, school refusal and truancy, cerebral palsy and child abuse and neglect. The cases are followed by questions to test the acquired knowledge of the student on these topics. This practical guide to child development is ideal for trainee paediatricians, registrars, paediatricians and general practitioners. Deals with developmental issues unlike comprehensive paediatric or child psychiatry texts Concise text providing practical tips Clinically and practically orientated (e.g. history, physical examination, assessment techniques) Comparison of normal and abnormal/normal development Definitions (Chapters.8,11,12) to clarify terms Several chapters (e.g. Chapters 8,9,10) inform about special problems/illnesses, which are increasing in incidence Online case scenarios on autism, ADHD, school refusal and truancy, cerebral palsy and child abuse and neglect are available on Student Consult. Combines physical and psychological problems in the development of children, which might be already present at birth (Cerebral Palsy) or which might be apparent later in life (Chapter 8)



Cell biology of the eye

Cell biology of the eye Author David S. McDevitt
ISBN-10 UOM:39015032525514
Release 1982
Pages 570
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Cell biology of the eye has been writing in one form or another for most of life. You can find so many inspiration from Cell biology of the eye also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Cell biology of the eye book for free.



Ocular Disease Mechanisms and Management E Book

Ocular Disease  Mechanisms and Management E Book Author Leonard A Levin
ISBN-10 9780702047411
Release 2010-03-10
Pages 704
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Ocular Disease—a newly introduced companion volume to the classic Adler’s Physiology of the Eye—correlates basic science and clinical management to describe the how and why of eye disease processes and the related best management protocols. Editors Leonard A. Levin and Daniel M. Albert—two of the world’s leading ophthalmic clinician-scientists—have recruited as contributors the most expert and experienced authorities available in each of the major areas of ophthalmic disease specific to ophthalmology: retina, cornea, cataract, glaucoma, uveitis, and more. The concise chapter structure features liberal use of color—with 330 full-color line artworks, call-out boxes, summaries, and schematics for easy navigation and understanding. This comprehensive resource provides you with a better and more practical understanding of the science behind eye disease and its relation to treatment. Covers all areas of disease in ophthalmology including retina, cornea, cataract, glaucoma, and uveitis for the comprehensive information you need for managing clinical cases. Presents a unique and pragmatic blend of necessary basic science and clinical application to serve as a clinical guide to understanding the cause and rational management of ocular disease. Features 330 full-color line artworks that translate difficult concepts and discussions into concise schematics for improved understanding and comprehension. Provides the expert advice of internationally recognized editors with over 40 years of experience together with a group of world class contributors in basic science and clinical ophthalmology.



Requirement for PDZ domain proteins in the development of the mouse lens and other tissues

Requirement for PDZ domain proteins in the development of the mouse lens and other tissues Author Charlene Rivera
ISBN-10 WISC:89100032176
Release 2007
Pages 191
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Requirement for PDZ domain proteins in the development of the mouse lens and other tissues has been writing in one form or another for most of life. You can find so many inspiration from Requirement for PDZ domain proteins in the development of the mouse lens and other tissues also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Requirement for PDZ domain proteins in the development of the mouse lens and other tissues book for free.



Veterinary Ocular Pathology E Book

Veterinary Ocular Pathology E Book Author Richard R. Dubielzig
ISBN-10 9780702044427
Release 2010-05-04
Pages 800
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Veterinary Ocular Pathology: A Comparative Review links the clinical features of ocular disease with gross and microscopic pathology to demonstrate the essential features observable during diagnosis. It is designed to be kept next to the microscope as an invaluable guide to accurate diagnosis in ocular pathology. The book presents a wide range of images of the highest quality. A unique and distinctive feature is the juxtaposition of clinical and pathological images while offering detailed enumeration of the diagnostic features. Expert comparative comments by Dr Daniel Albert and contextual information on relative incidence are provided throughout. The authors address spontaneous disease of the eye in all animal species, with a particular emphasis on companion species. In addition, specific, common or interesting conditions of exotic species are included. A convenient, comprehensive and easy-to-use reference for veterinary pathologists, veterinary ophthalmologists, students and comparative vision scientists. The first text devoted to the pathology of spontaneous diseases of the eyes and periocular tissues of domestic animal species Exceptionally high quality illustrations are presented throughout, demonstrating clinical features, gross pathology and histopathology Written by pathologists and clinicians Includes a chapter devoted to the pathology of conditions associated with glaucoma in domestic animals



Ocular Therapeutics

Ocular Therapeutics Author Thomas Yorio
ISBN-10 0080556779
Release 2011-04-28
Pages 536
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Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. It is the intent of this book to provide not only information on current approaches to treatment, but also in giving the reader a greater understanding as to what may become available for treating a number of important eye diseases. Each chapter features some new aspect of treatment that holds great promise for the future. The approach has been to concentrate on those areas of ocular diseases that are more prevalent. It also features new insight for drug delivery and for managing devasting diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States. This book will serve as an important resource as it contains a number of relevant references highlighted for their importance to the field. New investigators will be able to obtain an historical perspective for each of the topics and to develop an understanding of the new research directions that are underway. Ocular Therapeutics: Eye on New Discovery is more than a reference book, as it also provides an important glimpse into the near future. * Contains information that is vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. * Provides not only information on current approaches to treatment, but also gives the reader a greater understanding as to what may become available for treating a number of important eye diseases. * Historical perspective for each of the topics as well as an important glimpse into the near future to develop an understanding of the new research directions underway. * New insight for drug delivery and for managing devastating diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States



Embryology of the Eye and Its Adnexa

Embryology of the Eye and Its Adnexa Author Y. Robert Barishak
ISBN-10 9783805571791
Release 2001-01-01
Pages 132
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This monograph, unlike most previously published books on the subject, approaches the embryology of the eye and its adnexae from the perspective of gestational age, providing a unique overall view of the various structures of the eye at different stages of prenatal development. Embryogenesis, organogenesis and differentiation are three main periods that can be distinguished in the prenatal development of the human eye. The chapters in this book describe in detail the series of sequential events that occur during these periods from the fertilization of the ovum to, and after, birth. Superbly illustrated and clearly written, this text contains a wealth of information for residents in ophthalmology, neonatal and pediatric ophthalmologists, as well as for all ophthalmologists and physicians interested in developmental anomalies.



A Comprehensive Guide to Toxicology in Preclinical Drug Development

A Comprehensive Guide to Toxicology in Preclinical Drug Development Author Ali S. Faqi
ISBN-10 9780123878168
Release 2012-10-18
Pages 1024
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A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. Chapters written by world-renowned contributors who are experts in their fields Includes the latest research in preclinical drug testing and international guidelines Covers preclinical toxicology in small molecules and biologics in one single source



Progress of Lens Biochemistry Research Volume in honour of Prof Dr med J Nordmann

Progress of Lens Biochemistry Research Volume in honour of Prof  Dr  med  J  Nordmann Author O. Hockwin
ISBN-10 9789401015714
Release 2012-12-06
Pages 323
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On August 25,1976 Prof. Dr. med. JEAN NORDMANN, Emeritus Professor of Strasbourg University, will celebrate his 80th anniversary. The task of paying tribute to Professor NORDMANN's many services to ophthalmology in a way worthy of the occasion is so difficult that we decided to concentrate on the focal point of his life's work. In this issue scientists engaged in lens research from allover the world offer reports of their latest findings together with their best wishes and felicitations as a birthday gift to the Nestor of lens research. They thereby express their gratitude to Professor NORDMANN, who, with the lifelong in defatigable enthusiasm of a scientist, has most successfully persued the prob lems of lens metabolism. It is our sincerest hope that we may look forward to many more years in which to take advantage of Professor NORDMANN's superior knowledge. Among the contributions to this festive donation we miss the works of some authors who have always held Professor NORDMANN's special inter est. The editor has received several letters of longstanding friends who would have liked to submit a manuscript but had been unable to meet the deadline: Professor NORDMANN may rest assured that they, too, belong to the great number of congratulators from our field of research. We have been able to make this dedication thanks to Professor HENKES who readily agreed to publish our contributions in Documenta Ophthal mologica. Dr. Junk publishers have done their utmost to ensure prompt publication.



Clinical Contact Lens Practice

Clinical Contact Lens Practice Author Edward S. Bennett
ISBN-10 0781737052
Release 2005
Pages 1072
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This comprehensive text and reference addresses the full scope of contemporary contact lens science and practice. With two expert editors and 100 first-rate contributors, the book presents practitioners and students in optometry and ophthalmology with key facts on corneal anatomy, recent research, contact lens design, patient evaluation, clinical applications, patient education, and complications of contact lens wear. More than 600 illustrations complement the text. Clinical Contact Lens Practice will be the standard text for required contact lens courses and will be an invaluable everyday reference for practitioners.



Ocular Anatomy and Physiology

Ocular Anatomy and Physiology Author Al Lens
ISBN-10 1556427921
Release 2008
Pages 181
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Updated to include new material for beginners in ophthalmology and optometry, Ocular Anatomy and Physiology, Second Edition is an essential text that covers a range of fundamental information for students and clinicians. With collaborations from Al Lens, Sheila Coyne Nemeth, and Janice K. Ledford, Ocular Anatomy and Physiology, Second Edition now begins with a jump-start chapter to overview the topic for those new to the field of eye care. Chapter two delves into embryology—a topic rarely covered—and addresses each structure of the eye, including the bony orbit, eyebrows, eye lids, lacrimal system, extraocular muscles, and the globe. While the text continues to emphasize normal anatomy, each chapter contains a glossary of common disorders. Also included is a description of diagnostic methods for examining various tissues. The physiology of various structures and systems is explained, including the visual pathway, the inflammatory response, immunology, binocular vision, refractive errors, and accommodation. To enhance the reader's understanding of each topic, illustrations are provided. Features of the Second Edition: • New jump-start chapter for beginners • Details on diagnostic methods for each structure or segment, including optical coherence tomography and retinal thickness analysis • Glossary of common disorders at the end of each chapter With new features and information, Ocular Anatomy and Physiology, Second Edition is a valuable text for ophthalmic and optometric assistants, training facilities, and practices, as well as beginners in the field of eye care, including sales representatives and pre-med students.