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DNA

DNA Author James D. Watson
ISBN-10 9780385351201
Release 2017-08-22
Pages 512
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The definitive insider's history of the genetic revolution--significantly updated to reflect the discoveries of the last decade. James D. Watson, the Nobel laureate whose pioneering work helped unlock the mystery of DNA's structure, charts the greatest scientific journey of our time, from the discovery of the double helix to today's controversies to what the future may hold. Updated to include new findings in gene editing, epigenetics, agricultural chemistry, as well as two entirely new chapters on personal genomics and cancer research. This is the most comprehensive and authoritative exploration of DNA's impact--practical, social, and ethical--on our society and our world.



DNA

DNA Author James D. Watson
ISBN-10 9780307521484
Release 2009-01-21
Pages 464
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Fifty years ago, James D. Watson, then just twentyfour, helped launch the greatest ongoing scientific quest of our time. Now, with unique authority and sweeping vision, he gives us the first full account of the genetic revolution—from Mendel’s garden to the double helix to the sequencing of the human genome and beyond. Watson’s lively, panoramic narrative begins with the fanciful speculations of the ancients as to why “like begets like” before skipping ahead to 1866, when an Austrian monk named Gregor Mendel first deduced the basic laws of inheritance. But genetics as we recognize it today—with its capacity, both thrilling and sobering, to manipulate the very essence of living things—came into being only with the rise of molecular investigations culminating in the breakthrough discovery of the structure of DNA, for which Watson shared a Nobel prize in 1962. In the DNA molecule’s graceful curves was the key to a whole new science. Having shown that the secret of life is chemical, modern genetics has set mankind off on a journey unimaginable just a few decades ago. Watson provides the general reader with clear explanations of molecular processes and emerging technologies. He shows us how DNA continues to alter our understanding of human origins, and of our identities as groups and as individuals. And with the insight of one who has remained close to every advance in research since the double helix, he reveals how genetics has unleashed a wealth of possibilities to alter the human condition—from genetically modified foods to genetically modified babies—and transformed itself from a domain of pure research into one of big business as well. It is a sometimes topsy-turvy world full of great minds and great egos, driven by ambitions to improve the human condition as well as to improve investment portfolios, a world vividly captured in these pages. Facing a future of choices and social and ethical implications of which we dare not remain uninformed, we could have no better guide than James Watson, who leads us with the same bravura storytelling that made The Double Helix one of the most successful books on science ever published. Infused with a scientist’s awe at nature’s marvels and a humanist’s profound sympathies, DNA is destined to become the classic telling of the defining scientific saga of our age.



Genes Girls and Gamow

Genes  Girls and Gamow Author James D. Watson
ISBN-10 9780198606932
Release 2003
Pages 275
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In 1953 Watson and Crick discovered the double helical structure of DNA and Watson's personal account of the discovery, The Double Helix, was published in 1968. Genes, Girls and Gamow is also autobiographical, covering the period from when The Double Helix ends, in 1953, to a few years later, and ending with a Postscript bringing the story up to date. Here is Watson adjusting to new-found fame, carrying out tantalizing experiments on the role of RNA in biology, and falling in love. Thebook is enlivened with copies of handwritten letters from the larger than life character George Gamow, who had made significant contributions to physics but became intrigued by genes, RNA and the elusive genetic code. This is a tale of heartbreak, scientific excitement and ambition, laced with travelogue and '50s atmosphere.



The Path to the Double Helix

The Path to the Double Helix Author Robert Olby
ISBN-10 9780486166599
Release 2013-05-13
Pages 560
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Written by a noted historian of science, this in-depth account traces how Watson and Crick achieved one of science's most dramatic feats: their 1953 discovery of the molecular structure of DNA.



The Lives to Come

The Lives to Come Author Philip Kitcher
ISBN-10 9780684827056
Release 1997-08-04
Pages 397
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Addressing the moral, social, and political questions raised by the Human Genome Project, a scientific and philosophical study considers such areas as genetic therapy, genetic discrimination, and abortion



Genetics and the Unsettled Past

Genetics and the Unsettled Past Author Keith Wailoo
ISBN-10 9780813553368
Release 2012-03-15
Pages 370
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Our genetic markers have come to be regarded as portals to the past. Analysis of these markers is increasingly used to tell the story of human migration; to investigate and judge issues of social membership and kinship; to rewrite history and collective memory; to right past wrongs and to arbitrate legal claims and human rights controversies; and to open new thinking about health and well-being. At the same time, in many societies genetic evidence is being called upon to perform a kind of racially charged cultural work: to repair the racial past and to transform scholarly and popular opinion about the “nature” of identity in the present. Genetics and the Unsettled Past considers the alignment of genetic science with commercial genealogy, with legal and forensic developments, and with pharmaceutical innovation to examine how these trends lend renewed authority to biological understandings of race and history. This unique collection brings together scholars from a wide range of disciplines—biology, history, cultural studies, law, medicine, anthropology, ethnic studies, sociology—to explore the emerging and often contested connections among race, DNA, and history. Written for a general audience, the book’s essays touch upon a variety of topics, including the rise and implications of DNA in genealogy, law, and other fields; the cultural and political uses and misuses of genetic information; the way in which DNA testing is reshaping understandings of group identity for French Canadians, Native Americans, South Africans, and many others within and across cultural and national boundaries; and the sweeping implications of genetics for society today.



The Language of Life

The Language of Life Author Francis Collins
ISBN-10 9781847652096
Release 2010-12-09
Pages 332
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We are in the midst of a medical revolution: in just a few years, we will be able to have our complete DNA sequenced at an affordable cost. Analysing the content of our genomes will allow a powerful estimate of our future risks of illness - from cystic fibrosis and Huntington's disease, to cancer and diabetes - which will help us devise our own personalised blueprint of preventive medicine. This will have enormous implications on everything from our day-to-day choices like diet and exercise, to childbearing and health insurance - and it may even challenge what we thought we knew about our ethnic histories. Combining cutting-edge scientific research with practical advice, Francis Collins examines this remarkable phenomenon, which will transform healthcare worldwide. We now know that the language spoken by our DNA is the language of life itself, and in this important book Collins shows how reading that language will help save lives.



Genes and DNA

Genes and DNA Author Charlotte K. Omoto
ISBN-10 9780231503570
Release 2012-08-14
Pages 240
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Covering newsworthy aspects of contemporary biology -- gene therapy, the Human Genome Project, DNA testing, and genetic engineering -- as well as fundamental concepts, this book, written specifically for nonbiologists, discusses classical and molecular genetics, quantitative and population genetics -- including cloning and genetic diseases -- and the many applications of genetics to the world around us, from genetically modified foods to genetic testing. With minimal technical terminology and jargon, Genes and DNA facilitates conceptual understanding. Eschewing the organization of traditional genetics texts, the authors have provided an organic progression of information: topics are introduced as needed, within a broader framework that makes them meaningful for nonbiologists. The book encourages the reader to think independently, always stressing scientific background and current facts.



Life s Greatest Secret

Life s Greatest Secret Author Matthew Cobb
ISBN-10 9780465062669
Release 2015-07-07
Pages 464
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Everyone has heard of the story of DNA as the story of Watson and Crick and Rosalind Franklin, but knowing the structure of DNA was only a part of a greater struggle to understand life’s secrets. Life’s Greatest Secret is the story of the discovery and cracking of the genetic code, the thing that ultimately enables a spiraling molecule to give rise to the life that exists all around us. This great scientific breakthrough has had farreaching consequences for how we understand ourselves and our place in the natural world, and for how we might take control of our (and life’s) future. Life’s Greatest Secret mixes remarkable insights, theoretical dead-ends, and ingenious experiments with the swift pace of a thriller. From New York to Paris, Cambridge, Massachusetts, to Cambridge, England, and London to Moscow, the greatest discovery of twentieth-century biology was truly a global feat. Biologist and historian of science Matthew Cobb gives the full and rich account of the cooperation and competition between the eccentric characters—mathematicians, physicists, information theorists, and biologists—who contributed to this revolutionary new science. And, while every new discovery was a leap forward for science, Cobb shows how every new answer inevitably led to new questions that were at least as difficult to answer: just ask anyone who had hoped that the successful completion of the Human Genome Project was going to truly yield the book of life, or that a better understanding of epigenetics or “junk DNA” was going to be the final piece of the puzzle. But the setbacks and unexpected discoveries are what make the science exciting, and it is Matthew Cobb’s telling that makes them worth reading. This is a riveting story of humans exploring what it is that makes us human and how the world works, and it is essential reading for anyone who’d like to explore those questions for themselves.



The 1 000 Genome

The  1 000 Genome Author Kevin Davies
ISBN-10 1416570187
Release 2010-09-07
Pages 352
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In 2000, President Bill Clinton signaled the completion of the Human Genome Project at a cost in excess of $2 billion. A decade later, the price for any of us to order our own personal genome sequence—a comprehensive map of the 3 billion letters in our DNA—is rapidly and inevitably dropping to just $1,000. Dozens of men and women—scientists, entrepreneurs, celebrities, and patients—have already been sequenced, pioneers in a bold new era of personalized genomic medicine. The $1,000 genome has long been considered the tipping point that would open the floodgates to this revolution. Do you have gene variants associated with Alzheimer’s or diabetes, heart disease or cancer? Which drugs should you consider taking for various diseases, and at what dosage? In the years to come, doctors will likely be able to tackle all of these questions—and many more—by using a computer in their offices to call up your unique genome sequence, which will become as much a part of your medical record as your blood pressure. Indeed, many experts are advocating that all newborns have a complete genome analysis done so that preventive measures and preemptive medicine can begin early in life. How has this astonishing achievement been accomplished? And what will it mean for our lives? To research the story of this unfolding revolution, critically acclaimed science writer Kevin Davies has spent the past few years traveling to the leading centers and interviewing the entrepreneurs and pioneers in the race to achieve the $1,000 genome. He vividly brings to life the extraordinary drama of this grand scientific achievement, revealing the masterful ingenuity that has transformed the process of decoding DNA and delivering the information it possesses to the public at large. Davies also profiles the future of genomic medicine and thoughtfully explores the many pressing issues raised by the tidal wave of personal genetic information. Will your privacy be protected? Will you be pressured, by insurance companies or by your employer, to get your genome sequenced? What psychological toll might there be to discovering you are at risk for certain diseases like Alzheimer’s? And will the government or the medical establishment come between you and your genome? One thing that is not in question is that we are moving swiftly into the personalized medicine era, and The $1,000 Genome is an essential guide to this brave new future.



DNA

DNA Author James Watson
ISBN-10 9781407096247
Release 2008-09-04
Pages 624
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Along with Francis Crick, James Watson was the discoverer of the double helix structure of the DNA molecule, realising both how it was able to reproduce itself and how, through its immense variety, it was able to pass on genetic instructions from one generation to the next. Their discovery paved the way for fifty years of explosive scientific achievement of extraordinary importance, both in strictly scientific terms and in its technological and social significance. From Dolly the sheep to GM foods to designer babies, science-related newspaper headlines have been dominated by the implications of their work. In DNA, now fully updated and revised to include new findings in gene editing, epigenetics and agricultural chemistry, as well as two entirely new chapters on personal genomics and cancer research, Watson tells the story of this pioneering research and its impact on the world in which we live, from its beginnings to the present day. This is the most comprehensive and authoritative exploration of DNA’s impact – practical, social, and ethical – on our society and our world.



The Thread of Life

The Thread of Life Author Susan Aldridge
ISBN-10 0521465427
Release 1996-03-21
Pages 258
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DNA "fingerprinting," genetic engineering of food, genetic screening, gene therapy, the human genome project...there is no shortage of news these days about the genetic revolution. The purpose of this book is to take the interested reader behind the headlines to explore the fascinating world of molecular biology. Eschewing jargon, author Susan Aldridge gives an accessible account of the world of DNA and also explores its present and future applications. In the first part of the book, she explains what DNA is and how it functions within living organisms. In the second part, she explores genetic engineering and its applications to humans--such as gene therapy, genetic screening, and DNA fingerprinting. In the third, the author looks at the wider world of biotechnology and how genetic engineering can be applied to such problems as producing vegetarian cheese or cleaning up the environment. Finally, she explains how knowledge of the structure and function of genes sheds light on evolution and our place in the world. Aldridge has written with a light touch full of historical references; her achievement will make rewarding reading for anyone who reads popular accounts of the life sciences.



Maurice Wilkins The Third Man of the Double Helix

Maurice Wilkins  The Third Man of the Double Helix Author Maurice Wilkins
ISBN-10 9780191578144
Release 2005-07-14
Pages 314
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The Nobel Prize for the discovery of the structure of DNA was given to three scientists - James Watson, Francis Crick, and Maurice Wilkins. It was the experimental work of Wilkins and his colleague Rosalind Franklin that provided the clues to the structure. Here, Wilkins, who died in 2004, gives us his own account of his life, his early work in physics, the tensions and exhilaration of working on DNA, and his much discussed difficult relationship with his colleague Rosalind. This is a highly readable, and often moving account from a highly distinguished scientist who played one of the key roles in the historic discovery of the molecule behind inheritance.



Watson And DNA

Watson And DNA Author Victor K. McElheny
ISBN-10 9780786730148
Release 2009-03-25
Pages 400
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The most influential scientist of the last century, James Watson has been at dead center in the creation of modern molecular biology. This masterful biography brings to life the extraordinary achievements not only of Watson but also all those working on this cutting edge of scientific discovery, such as Walter Gilbert, Francis Crick, François Jacob, and David Baltimore. From the ruthless competition in the race to identify the structure of DNA to a near mutiny in the Harvard biology department, to clashes with ethicists over issues in genetics, Watson has left a wake of detractors as well as fans. Victor McElheny probes brilliantly behind the veil of Watson's own invented persona, bringing us close to the relentless genius and scientific impresario who triggered and sustained a revolution in science.



The Epigenetics Revolution

The Epigenetics Revolution Author Nessa Carey
ISBN-10 9780231530712
Release 2012-03-06
Pages 352
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Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism’s genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field’s arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.



Francis Crick

Francis Crick Author Matt Ridley
ISBN-10 9780062200662
Release 2012-01-17
Pages 224
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Francis Crick—the quiet genius who led a revolution in biology by discovering, quite literally, the secret of life—will be bracketed with Galileo, Darwin, and Einstein as one of the greatest scientists of all time. In his fascinating biography of the scientific pioneer who uncovered the genetic code—the digital cipher at the heart of heredity that distinguishes living from non-living things—acclaimed bestselling science writer Matt Ridley traces Crick's life from middle-class mediocrity in the English Midlands through a lackluster education and six years designing magnetic mines for the Royal Navy to his leap into biology at the age of thirty-one and its astonishing consequences. In the process, Ridley sheds a brilliant light on the man who forever changed our world and how we understand it.



Cracking the Genome

Cracking the Genome Author Kevin Davies
ISBN-10 0801871409
Release 2002-10-29
Pages 327
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This newly updated edition sheds light on the secrets of the sequence, highlighting the myriad ways in which genomics will impact human health for generations to come.