Download or read online books in PDF, EPUB and Mobi Format. Click Download or Read Online button to get book now. This site is like a library, Use search box in the widget to get ebook that you want.

E coli

E  coli Author Michael Donnenberg
ISBN-10 9780080494814
Release 2002-10-09
Pages 417
Download Link Click Here

Although most strains of E. coli bacteria are harmless and live in the intestines of healthy humans and animals, several strains can produce powerful toxins and cause severe illness in humans. This versatile pathogen is best known for being transmitted to humans through contaminated foods — such as undercooked meat and unpasteurized fruit juice — and has attracts much attention when serious outbreaks occur. E. coli is capable of causing a wide variety of diseases — from urinary tract infections to meningitis. A considerable amount of media coverage has recently been devoted to one particular strain of E. coli, responsible for an estimated 73,000 cases of infection and 61 deaths in the United States each year. Knowing more about the biology, the evolution, and the genetic basis of this pathogen is crucial to future prevention of infection and illness. Pathogenic E. coli is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. Pathogenic E. coli concludes with a presentation of virulance factors, common to two or more pathotypes. This unique collection presents timely and vital information on understanding the inner workings of E. coli, which will lend key insights into disease prevention research. Single source of information of E. coli pathogenesis Expert authors Comprehensive coverage Molecular mechanisms Biology, evolution and genomics Recent advances



Escherichia coli

Escherichia coli Author Michael Donnenberg
ISBN-10 9780123977779
Release 2013-06-12
Pages 612
Download Link Click Here

The 2e of Escherichia coli is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. This work concludes with a presentation of virulence factors common to two or more pathotypes. The book is a great resource for references and up-to-date knowledge for anyone who studies E. coli pathogenesis, either as established investigators or investigators new to the field. It is also an excellent text for those who teach mechanisms of pathogenesis to graduate students and medical students and wish to have a source of knowledge from which to develop lectures. Offers a single source of information of E. coli pathogenesis written by expert authors Presents comprehensive coverage on molecular mechanisms, biology, evolution and genomics and recent advances



Pathogenicity Islands and the Evolution of Pathogenic Microbes

Pathogenicity Islands and the Evolution of Pathogenic Microbes Author J. Hacker
ISBN-10 9783662092170
Release 2013-03-09
Pages 234
Download Link Click Here

It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well due to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.



Enteropathogenic and enterohemorrhagic E coli ecology pathogenesis and evolution

Enteropathogenic and enterohemorrhagic E  coli  ecology  pathogenesis and evolution Author Elizabeth L. Hartland
ISBN-10 9782889191536
Release
Pages
Download Link Click Here

Enteropathogenic and enterohemorrhagic E. coli are important causes of gastrointestinal disease worldwide. As part of their pathogenesis, EPEC and EHEC cause a distinctive lesion on the intestinal mucosa known as an attaching and effacing (A/E) lesion. A/E lesion formation requires a type III secretion system that injects multiple effector proteins into the cell. Despite their shared mechanism of intestinal colonization, EPEC and EHEC exhibit substantial differences in epidemiology and clinical disease. In particular, EHEC produces a potent Shiga toxin that is associated with development of the haemolytic uremic syndrome (HUS), an acute form of renal failure. This Research Topic will examine interactions between attaching and effacing bacteria and the host cell, and discuss EPEC/EPEC ecology, genomics and animal models of disease. Articles will centre on pathogen evolution, novel adhesins, type III effector biology and bacterium-host responses during infection.



Pathogenicity Islands and the Evolution of Pathogenic Microbes

Pathogenicity Islands and the Evolution of Pathogenic Microbes Author Jörg Hinrich Hacker
ISBN-10 WISC:89081095218
Release 2002
Pages
Download Link Click Here

Pathogenicity Islands and the Evolution of Pathogenic Microbes has been writing in one form or another for most of life. You can find so many inspiration from Pathogenicity Islands and the Evolution of Pathogenic Microbes also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Pathogenicity Islands and the Evolution of Pathogenic Microbes book for free.



Pathogenomics

Pathogenomics Author Jörg Hacker
ISBN-10 9783527607518
Release 2006-12-13
Pages 616
Download Link Click Here

The first book on this young, highly dynamic, and expanding field. This comprehensive, interdisciplinary text focuses on those pathogenic bacteria that are of high scientific and public health interest, yet which also display great potential for the development of new diagnostic, prophylactic and therapeutic procedures. The authors cover all aspects of pathogenomics, including methods, genomics and applications. In addition, the ongoing development of genome, transcriptome, proteome and bioinformatic analyses of pathogenic microorganisms and their host interactions makes for a comprehensive introduction to the field of modern genomic analysis. This result is invaluable to researchers and students wishing to gain a general overview of microbial functional genome analysis and pathogenesis, while also representing a good starting point for those new to the area.



Pathogenic Escherichia Coli

Pathogenic Escherichia Coli Author Pina M. Fratamico
ISBN-10 1910190772
Release 2018-04
Pages 266
Download Link Click Here

In this book, renowned experts provide timely and up-to-date reviews of current E. coli omics, molecular- and cellular-biology research. Topics range from E. coli genome plasticity and evolution to the application of omics technologies for in silico modeling to understand stress-triggered physiological responses. Essential reading.



Population Genetics of Bacteria

Population Genetics of Bacteria Author Seth T. Walk
ISBN-10 9781555815356
Release 2011-04-20
Pages 360
Download Link Click Here

Revisit the work of a pioneering innovator… • Explores the field of bacterial population genetics by highlighting the work of Thomas S. Whittam, best known for his work with enterohemorrhagic E. coli. • Features a compilation of research projects and ideas stemming from Dr. Whittam’s work that presents a broad perspective on the historical development of bacterial population genetics.



Genomics of Foodborne Bacterial Pathogens

Genomics of Foodborne Bacterial Pathogens Author Martin Wiedmann
ISBN-10 1441976868
Release 2011-02-04
Pages 524
Download Link Click Here

Foodborne illnesses caused by various bacterial, viral, and fungal pathogens lead to a high number of morbidity and mortality in the U.S. and throughout the world. Recent advances in microbial genomics have significantly improved our understanding of the physiology, evolution, ecology, epidemiology, and pathogenesis of different foodborne pathogens. This book focuses on the genomics of foodborne bacterial pathogens. It begins with a brief overview of the recent advances in microbial genomics and the impact of genomics on food safety research. Then, eight chapters follow that elaborate some in-depth reviews on the genomics of several common foodborne bacterial pathogens including Bacillus, Campylobacter, Clostridium, Escherichia coli, Listeria, Salmonella, Staphylococcus, and Vibrio. Finally, the last four chapters focus on some current genomic, transcriptomic, and proteomic technologies and their applications in studying the epidemiology, evolution, and pathogenesis of foodborne bacterial pathogens. Genomics of Foodborne Bacterial Pathogens can be used as a reference by scientists and professionals in academia, government, and industry who are interested in understanding microbial genomics and using genomics tools to study foodborne bacterial pathogens. This book can also be used as a textbook for instructors and professors who teach food microbiology or microbial genomics-related courses at the post-graduate level.



Microbial Pathogenomics

Microbial Pathogenomics Author Hilde de Reuse
ISBN-10 9783805591928
Release 2009-01-01
Pages 214
Download Link Click Here

'Microbial Pathogenomics' contains a unique collection of reviews demonstrating how genomics has revolutionized our understanding of virulence, host-adaptation strategies and the evolution of bacterial pathogens. Current technologies - computational tools and functional approaches to genome analysis - are carefully documented and clearly illustrated. These include visualization tools for genome comparison, databases, in silico metabolic reconstructions and function prediction as well as interactomics for the study of protein-protein interactions. The concepts of pan-genomics and reverse vaccinology are introduced as strategies when addressing the challenge presented by bacterial diversity in the prevention and treatment of infectious diseases. The authors explore individual bacterial pathogens and discuss the mechanisms that have contributed to their evolutionary success. Special cases of host adaptation, for example, are illustrated by Helicobacter pylori and 'Mycobacterium tuberculosis' which are human-specific and highly persistent; further bacteria discussed include 'Escherichia coli, Campylobacter, Pseudomonas, Legionella, Bartonella, Burkholderia' and 'Staphylococcus'.'Microbial Pathogenomics' provides the reader with a global view of key aspects and future trends in bacterial pathogenomics and evaluates their impact on the understanding and treatment of infectious diseases. Well illustrated and accessible to both specialists and nonspecialists, it is recommended not only for researchers in microbiology, genomics and biotechnology, but also for lecturers and teachers.



Microbial Pathogenomics

Microbial Pathogenomics Author Hilde de Reuse
ISBN-10 9783805591928
Release 2009-01-01
Pages 214
Download Link Click Here

'Microbial Pathogenomics' contains a unique collection of reviews demonstrating how genomics has revolutionized our understanding of virulence, host-adaptation strategies and the evolution of bacterial pathogens. Current technologies - computational tools and functional approaches to genome analysis - are carefully documented and clearly illustrated. These include visualization tools for genome comparison, databases, in silico metabolic reconstructions and function prediction as well as interactomics for the study of protein-protein interactions. The concepts of pan-genomics and reverse vaccinology are introduced as strategies when addressing the challenge presented by bacterial diversity in the prevention and treatment of infectious diseases. The authors explore individual bacterial pathogens and discuss the mechanisms that have contributed to their evolutionary success. Special cases of host adaptation, for example, are illustrated by Helicobacter pylori and 'Mycobacterium tuberculosis' which are human-specific and highly persistent; further bacteria discussed include 'Escherichia coli, Campylobacter, Pseudomonas, Legionella, Bartonella, Burkholderia' and 'Staphylococcus'.'Microbial Pathogenomics' provides the reader with a global view of key aspects and future trends in bacterial pathogenomics and evaluates their impact on the understanding and treatment of infectious diseases. Well illustrated and accessible to both specialists and nonspecialists, it is recommended not only for researchers in microbiology, genomics and biotechnology, but also for lecturers and teachers.



Tuberculosis E Book

Tuberculosis E Book Author H. Simon Schaaf
ISBN-10 9781437711066
Release 2009-03-24
Pages 1046
Download Link Click Here

This book provides all the vital information you need to know about tuberculosis, especially in the face of drug-resistant strains of the disease. Coverage includes which patient populations face an elevated risk of infection, as well as which therapies are appropriate and how to correctly monitor ongoing treatment so that patients are cured. Properly administer screening tests, interpret their results, and identify manifestations of the disease, with authoritative guidance from expert clinicians from around the world. Discusses screening tests for tuberculosis so you can interpret their results and identify not only common manifestations of the disease, but also those that are comparatively rare—such as tuberculosis in pregnant women. Covers all clinical aspects of tuberculosis in children, including current practices on managing those infected with HIV. Provides details on how best to interact with the public health system in both industrialized and developing countries. Addresses the social aspects of tuberculosis and presents the latest advances on new and potential vaccines against tuberculosis. Offers the expertise of internationally recognized tuberculosis clinicians to provide you with well-rounded, global coverage. Features numerous illustrations to provide clear and detailed depictions of rare manifestations of tuberculosis.



Sequence Evolution Function

Sequence     Evolution     Function Author Eugene Koonin
ISBN-10 1402072740
Release 2002-11-30
Pages 462
Download Link Click Here

Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.



Plant Pathogenic Bacteria

Plant Pathogenic Bacteria Author Robert W. Jackson
ISBN-10 9781904455370
Release 2009-01-01
Pages 330
Download Link Click Here

Reviews the most important developments in the field providing an invaluable up-to-date summary. The first two chapters tackle bacterial evolution, diversity and taxonomy; topics that have been transformed by molecular biology and genomics analyses. The third chapter delves into the crucially understudied area of pathogen adaptation to the plant apoplast environment. This is followed by seven chapters focusing on specific plant pathogens: Agrobacterium, Leifsonia, Pectobacterium, Pseudomonas, Ralstonia, Xanthomonas, and Xylella. The next four chapters review specific, intensively studied areas of research in the plant pathogen field: microbe associated molecular patterns (MAMPs) and innate immunity; use of bacterial virulence factors to suppress plant defence; cyclic di-GMP signalling and the regulation of virulence; and plasmids and the spread of virulence. The final chapter covers the critical area of bioinformatics.



Computational analysis of genome evolution

Computational analysis of genome evolution Author Aaron E. Darling
ISBN-10 WISC:89094352788
Release 2006
Pages 184
Download Link Click Here

Computational analysis of genome evolution has been writing in one form or another for most of life. You can find so many inspiration from Computational analysis of genome evolution also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Computational analysis of genome evolution book for free.



Horizontal Gene Transfer in the Evolution of Pathogenesis

Horizontal Gene Transfer in the Evolution of Pathogenesis Author Michael Hensel
ISBN-10 9781139472050
Release 2008-06-30
Pages
Download Link Click Here

Horizontal gene transfer is a major driving force in the evolution of many bacterial pathogens. The development of high-throughput sequencing tools and more sophisticated genomic and proteomic techniques in recent years has resulted in a better understanding of this phenomenon. Written by leading experts in the field, this edited volume is aimed at graduate students and researchers and provides an overview of current knowledge relating to the evolution of microbial pathogenicity. This volume provides an overview of the mechanisms and biological consequences of the genome rearrangements resulting from horizontal gene transfer, in both prokaryotes and eukaryotes, as well as overviews of the key mobile genetic elements involved. Subsequent chapters focus on paradigms for the evolution of important bacterial pathogens, including Salmonella enterica, Streptococcus pneumoniae, and Staphylococcus aureus. The influence of socioeconomic parameters in the dissemination of transferable elements, such as antibiotic resistant genes in bacteria, is also discussed.



Mass Spectrometry for Microbial Proteomics

Mass Spectrometry for Microbial Proteomics Author Haroun N. Shah
ISBN-10 1119991927
Release 2010-10-28
Pages 534
Download Link Click Here

New advances in proteomics, driven largely by developments in mass spectrometry, continue to reveal the complexity and diversity of pathogenic mechanisms among microbes that underpin infectious diseases. Therefore a new era in medical microbiology is demanding a rapid transition from current procedures to high throughput analytical systems for the diagnosis of microbial pathogens. This book covers the broad microbiological applications of proteomics and mass spectrometry. It is divided into six sections that follow the general progression in which most microbiology laboratories are approaching the subject –Transition, Tools, Preparation, Profiling by Patterns, Target Proteins, and Data Analysis.