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Inhibition of Polyamine Metabolism

Inhibition of Polyamine Metabolism Author Peter McCann
ISBN-10 9780323152327
Release 2012-12-02
Pages 398
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Inhibition of Polyamine Metabolism: Biological Significance and Basis for New Therapies provides an overview of the field concerning polyamine biosynthesis inhibitors. The book is comprised of chapters which describe the compounds which are in use; the rationale for the design of such inhibitors; their synthesis and action; their biological effects on mammalian cells and tissues, plants, and microorganisms including protozoal parasites; and a review of the clinical experience with these inhibitors. The major beneficial effect which the wide availability of these inhibitors has had on the field of polyamine research in general is likewise demonstrated. Biochemists, pharmacologist, and cellular physiologists will find this text very useful.



Inhibition of Polyamine Metabolism Biological Significance and Basis for New Therapies

Inhibition of Polyamine Metabolism  Biological Significance and Basis for New Therapies Author PP McCann (Ed)
ISBN-10 OCLC:985930307
Release 1987
Pages
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Inhibition of Polyamine Metabolism Biological Significance and Basis for New Therapies has been writing in one form or another for most of life. You can find so many inspiration from Inhibition of Polyamine Metabolism Biological Significance and Basis for New Therapies also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Inhibition of Polyamine Metabolism Biological Significance and Basis for New Therapies book for free.



Progress in Polyamine Research

Progress in Polyamine Research Author V. Zappia
ISBN-10 9781468456370
Release 2012-12-06
Pages 780
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This book contains the scientific contributions presented at an International Symposium held in Sorrento, Italy, in June 1988 under the auspices of the University of Naples, the Italian Society of Biochemistry, and the National Research Council. The modern history of polyamines dates back to 1958 when the Tabors and Rosenthal first described the outlines of their biological synthesis. From then on, and particularly in the last ten years, a veri table explosion of Literature, characterized by thousands of papers, has witnessed the interest of the scientific community toward these molecules. Perhaps the old statement that "polyamines are molecules in search of a function" is no longer true today. A large number of effects exerted by these simple molecules are well known, and in many cases the mechanisms underlying these effects have been elucidated. The first section of the volume is entirely devoted to the enzymology and molecular biology of ornithine decarboxylase. Since its discovery by Gale more than forty years ago, this can be considered among the most widely studied enzymes in biology, and one of the most complex models in enzyme regulation. The mechanism of control of the enzyme activity at the transcriptional, post-transcriptional and post-translational levels, as well as the fine regulation by antizyme, are discussed in detail. The second group of contributions deals wi th AdoMet decarboxylase, propylamine transferase, polyamine oxidase and the other enzymes related to polyamine interconversion and regeneration.



Progress in Human African Trypanosomiasis Sleeping Sickness

Progress in Human African Trypanosomiasis  Sleeping Sickness Author Michel Dumas
ISBN-10 9782817808574
Release 2013-12-01
Pages 346
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Human African Trypaniosomiasis (HAT) or sleeping sickness is an old disease to be now considered as reemergent. HAT is endemic in 36 sub-Saharan African countries, in areas where tsetse flies are found. The public health importance of HAT is underestimated, but the disease causes severe social disruption in many rural areas. Along the past fifteen years, numerous studies were made, and now, the mechanisms involved in the disease pathogenesis and in the characteristics of sleep-wake disruption become to be better understood. But, since 50 years, when current drugs were introduced, problems regarding HAT chemotherapy have not been solved. Nevertheless, in-depth studies about trypanosome metabolism have permitted to discover new drug targets. Written by specialists who are very experienced in their respective fields, the contributions provide an indispensable tool for practitioners and scientists.



The Prostate as an Endocrine Gland

The Prostate as an Endocrine Gland Author Richard J. Ablin
ISBN-10 0849353645
Release 1989-11-30
Pages 232
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This unique publication illustrates that the prostate elaborates an array of local hormones or "autocoids" and how these influence prostatic growth, function and oncogenesis. It describes how familiarity with these participants and how they effect the character and direction of prostatic function may suggest diagnostic markers of malfunction and new sites and modes of therapeutic intervention. The catholic scope and authorship of the work seeks to integrate the views of those urologists, reproductive physiologists and endocrinologists who presently work with the prostate. It attempts to show all other biologists the full range of the gland's activities and participating molecules. Included are: oncogenes, mitogens, polyamines, prostaglandins, growth factors, antigens, and the familiar steroid, peptide and protein hormones. This volume is unique in its point of view and in the new concepts it presents. Addressed are actions of spermine-binding protein and osteoblastic mitogens, consequences of inhibin/thyrotropin-releasing hormone balance, and urokinase effects. Covered also are androgen modulation of vasoactive intestinal polypeptides, evidence of a prostatolymphoreticular system, secretion of dihydrotestosterone, and a model of the inter-dependence of prostatic epithelium and stroma. This unique new volume is of great value to those in urology, internal medicine, physiology, endocrinology and pharmacology.



Plant Biotechnology and Molecular Markers

Plant Biotechnology and Molecular Markers Author S. Srivastava
ISBN-10 1402019114
Release 2004-04-30
Pages 400
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The genesis of the volume, Plant Biotechnology and Molecular Markers, has been the occasion of the retirement of Professor Sant Saran Bhojwani from the Department of Botany, University of Delhi. For Professor Bhojwani, retirement only means relinquishing the chair as being a researcher and a teacher which has always been a way of life to him. Professor Bhojwani has been an ardent practitioner of modern plant biology and areas like Plant Biotechnology and Molecular Breeding have been close to his heart. The book contains original as well as review articles contributed by his admirers and associates who are experts in their area of research. While planning this contributory book our endeavour has been to incorporate articles that cover the entire gamut of Plant Biotechnology, and also applications of Molecular Markers. Besides articles on in vitro fertilization and micropropagation, there are articles on forest tree improvement through genetic engineering. Considering the importance of conservation of our precious natural wealth, one article deals with cryopreservation of plant material. Chapter on molecular marker considers DNA indexing as markers of clonal fidelity of in vitro regenerated plants and prevention against bio-piracy. A couple of write-ups also cover stage-specific gene markers, DNA polymorphism and genetic engineering, including raising of stress tolerant plants to sustain productivity and help in reclamation of degraded land.



Cancer Research

Cancer Research Author
ISBN-10 NWU:35558001342324
Release 1988
Pages
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Cancer Research has been writing in one form or another for most of life. You can find so many inspiration from Cancer Research also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Cancer Research book for free.



International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine

International Journal of Radiation Biology and Related Studies in Physics  Chemistry  and Medicine Author
ISBN-10 UIUC:30112107025378
Release 1989
Pages
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International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine has been writing in one form or another for most of life. You can find so many inspiration from International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine also informative, and entertaining. Click DOWNLOAD or Read Online button to get full International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine book for free.



The Role of Polyamines in Hormonally Stimulated Bone Resorption

The Role of Polyamines in Hormonally Stimulated Bone Resorption Author Rita L. Cohen Lucas
ISBN-10 NWU:35558002841860
Release 1989
Pages 125
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The Role of Polyamines in Hormonally Stimulated Bone Resorption has been writing in one form or another for most of life. You can find so many inspiration from The Role of Polyamines in Hormonally Stimulated Bone Resorption also informative, and entertaining. Click DOWNLOAD or Read Online button to get full The Role of Polyamines in Hormonally Stimulated Bone Resorption book for free.



Tropical diseases

Tropical diseases Author Sushil Kumar
ISBN-10 UOM:39015043242802
Release 1994
Pages 778
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Contributed articles



Goodman Gilman s the Pharmacological Basis of Therapeutics

Goodman   Gilman s the Pharmacological Basis of Therapeutics Author Louis Sanford Goodman
ISBN-10 MINN:31951D01253435P
Release 1996
Pages 1905
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For more than fifty years, scientists, clinicians, & students have relied on "Goodman & Gilman for the final word on the pharmacokinetics, mechanisms of action & therapeutic application of drugs. This edition sustains that proud tradition & infuses the latest information on molecular pharmacology as it redefines the definite database of pharmacologic therapeutics. As a course text or a daily reference in clinical practice, "G & G" offers the optimal mix of basic science & clinical coverage as it pertains to effective drug therapy.



American Journal of Physiology

American Journal of Physiology Author
ISBN-10 UOM:39015027100448
Release 1993
Pages
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"The William Townsend Porter memorial volume": v. 158.



Anticancer Research

Anticancer Research Author
ISBN-10 NWU:35558004044786
Release 1998
Pages
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Boyce Thompson Institute collected research papers

Boyce Thompson Institute collected research papers Author Boyce Thompson Institute for Plant Research
ISBN-10 CORNELL:31924084861115
Release 1989
Pages
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Boyce Thompson Institute collected research papers has been writing in one form or another for most of life. You can find so many inspiration from Boyce Thompson Institute collected research papers also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Boyce Thompson Institute collected research papers book for free.



Journal of Developmental Physiology

Journal of Developmental Physiology Author
ISBN-10 UIUC:30112009469823
Release 1991
Pages
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Journal of Developmental Physiology has been writing in one form or another for most of life. You can find so many inspiration from Journal of Developmental Physiology also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Journal of Developmental Physiology book for free.



The Cancer Bulletin

The Cancer Bulletin Author
ISBN-10 NWU:35558002631022
Release 1991
Pages
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The Cancer Bulletin has been writing in one form or another for most of life. You can find so many inspiration from The Cancer Bulletin also informative, and entertaining. Click DOWNLOAD or Read Online button to get full The Cancer Bulletin book for free.



Polyamine Cell Signaling

Polyamine Cell Signaling Author Jian-Ying Wang
ISBN-10 9781597451451
Release 2007-11-19
Pages 490
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Polyamines are organic cations found in all eukaryotic cells and intimately involved in, and required for, distinct biological functions. An increasing body of evidence indicates that the regulation of cellular polyamines is a central convergence point for the multiple signaling pathways driving various cellular functions. Over the last decade, considerable progress has been made in und- standing the molecular functions of cellular polyamines. These significant findings provide a fundamental basis to not only define the exact role of polyamines in physiology, but also to develop new therapeutic approaches for cancers and other diseases. The major objective of this book is to provide a timely and long lasting guide for investigators in the fields of polyamines, physiology, pharmacology, and cancer research. It will provide a foundation based on research and address the potential for subsequent applications in clinical practice. Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research is divided into four main parts: Part I: Polyamines in Signal Transduction of Cell Proliferation Part II: Polyamines in Cellular Signaling of Apoptosis, Carcinogenesis, and Cancer Therapy Part III: Polyamines in Cell Motility and Cell–Cell Interactions Part IV: Polyamine Homeostasis and Transport This book not only covers the current state-of-the-art findings relevant to cellular and molecular functions of polyamines, but also provides the underlying conceptual basis and knowledge regarding potential therapeutic targeting of polyamines and polyamine metabolism. These points are addressed by int- nationally recognized experts in their contributions to this book.