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Intellectual Property Issues

Intellectual Property Issues Author Ulrich Storz
ISBN-10 9783642295263
Release 2012-05-11
Pages 108
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SpringerBriefs in Biotech Patents present timely reports of intellectual properties (IP) issues and patent aspects in the field of biotechnology. This new volume in the series focuses on the particular IP issues of therapeutics, vaccines and molecular diagnostics. The first chapter concentrates on basics principles for protecting antibody compounds. Additional ways to create follow-up protection for antibody therapeutics are also discussed. The second chapter gives an overview of the patent landscape in molecular diagnostics, and discusses issues of patentability with respect to the different technologies and compounds used therein. The third chapter gives a broad overview of areas of law that are particularly relevant to the patenting of peptide vaccines and therapeutic peptides as products and in compositions. The scope of patentable subject matter is discussed, as it has been the focus of much wrangling and debate in the courts.



Ethics Dumping

Ethics Dumping Author Doris Schroeder
ISBN-10 9783319647319
Release 2017-12-04
Pages 134
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This book is published under a CC BY 4.0 license. This book provides original, up-to-date case studies of “ethics dumping” that were largely facilitated by loopholes in the ethics governance of low and middle-income countries. It is instructive even to experienced researchers since it provides a voice to vulnerable populations from the fore mentioned countries. Ensuring the ethical conduct of North-South collaborations in research is a process fraught with difficulties. The background conditions under which such collaborations take place include extreme differentials in available income and power, as well as a past history of colonialism, while differences in culture can add a new layer of complications. In this context, up-to-date case studies of unethical conduct are essential for research ethics training.



Nanoparticles in Lung Cancer Therapy Recent Trends

Nanoparticles in Lung Cancer Therapy   Recent Trends Author Abhijit Bandyopadhyay
ISBN-10 9788132221753
Release 2014-11-14
Pages 65
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This brief provides an insight into the present scenario of the role of nanotechnology in the diagnosis and treatment of lung cancer at an early stage. Currently, lung cancer is the subject of major concern owing to the very high mortality rate throughout the world. Most of the conventional treatment methods such as surgery, chemotherapy, radiotherapy, etc., fail to prolong life of the patients. Incidents of recurrence are also very common in case of lung cancer. Researchers have shown that nanoparticles may act as a powerful anti cancer tool, especially for lung cancer. Unique surface properties and easy surface functionalization of nanoparticles enable early detection, diagnosis, imaging and treatment of lung cancer. The authors have elaborately presented how various nanoparticles (natural, semi synthetic and synthetic) may help in the treatment of lung cancer. They have also detailed works of various scientists who succeeded in developing effective nanoparticles and enabled very specific lung cancer therapy without any undesirable side effects and minimized death.



A Practical Guide to Drug Development in Academia

A Practical Guide to Drug Development in Academia Author Daria Mochly-Rosen
ISBN-10 9783319022017
Release 2014-07-08
Pages 176
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"A lot of hard-won knowledge is laid out here in a brief but informative way. Every topic is well referenced, with citations from both the primary literature and relevant resources from the internet." Review from Nature Chemical Biology Written by the founders of the SPARK program at Stanford University, this book is a practical guide designed for professors, students and clinicians at academic research institutions who are interested in learning more about the drug development process and how to help their discoveries become the novel drugs of the future. Often many potentially transformative basic science discoveries are not pursued because they are deemed ‘too early’ to attract industry interest. There are simple, relatively cost-effective things that academic researchers can do to advance their findings to the point that they can be tested in the clinic or attract more industry interest. Each chapter broadly discusses an important topic in drug development, from preclinical work in assay design through clinical trial design, regulatory issues and marketing assessments. After the practical overview provided here, the reader is encouraged to consult more detailed texts on specific topics of interest. "I would actually welcome it if this book’s intended audience were broadened even more. Younger scientists starting out in the drug industry would benefit from reading it and getting some early exposure to parts of the process that they’ll eventually have to understand. Journalists covering the industry (especially the small startup companies) will find this book a good reality check for many an over-hopeful press release. Even advanced investors who might want to know what really happens in the labs will find information here that might otherwise be difficult to track down in such a concentrated form."



Cancer Nanotheranostics

Cancer Nanotheranostics Author P. Gopinath
ISBN-10 9789812874351
Release 2015-03-10
Pages 119
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This Brief provides a clear insight of the recent advances in the field of cancer theranostics with special emphasis upon nano scale carrier molecules (polymeric, protein and lipid based) and imaging agents (organic and inorganic).



Biopatent Law Patent Strategies and Patent Management

Biopatent Law  Patent Strategies and Patent Management Author Andreas Hübel
ISBN-10 9783642248467
Release 2012-01-05
Pages 44
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Patents protecting biotechnological invention are becoming ever more important. Because biotechnology has many differences with respect to other technologies, lessons learned in other fields of technology cannot simply be transferred to adopt a suitable strategy for dealing with biotechnology inventions. In this volume, general aspects of biopatent law will be discussed. This involves questions of patentability, including ethical issues and issues of technicality, as well as questions of patent exhaustion in cases were reproducible subject matter, like cells or seeds, is protected. Moreover, active and passive patent strategies are addressed. Further, insight will be given into patent lifetime management and additional protective measures, like supplementary protection certificates and data exclusivity. Here, strategies are discussed how market exclusivity can be extended as long as possible, which is particularly important for biopharmaceutical drugs, which create high R&D costs.



Polysaccharides

Polysaccharides Author Kishan Gopal Ramawat
ISBN-10
Release 2021-01-14
Pages 3000
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This reference work presents comprehensive information about one of the most important and most wide-spread classes of (bio)organic compounds: the polysaccharides. The comprehensive and thoroughly up-to-date handbook presents the sources, identification, analysis, biosynthesis, biotechnology and applications of important polysaccharides likes starches, cellulose, chitin, gum and microbial polysaccharides. Polysaccharides can exhibit complex structure and various functional activities. These biomacromolecules can therefore serve as raw materials for various different materials, e.g. rayon, cellulose acetate, celluloid, and nitrocellulose; and they find multiple applications, for instance as surgical threads (chitin), as sources of energy, dietary fibers, as blood flow adjuvants, in cosmetics, emulsion stabilizers, film formers, binders, viscosity increasing agents, or skin conditioning agenta, as food additives in gums, chewing gum bases, and as vaccines. Polysaccharides form the basis for useful products, like xanthan gum, dextran, welan gum, gellan gum, diutan gum and pullulan. Some of the polysaccharide-derived products have interesting and useful properties and show biological activities, such as immunomodulatory, antibacterial, anti-mutagenic, radioprotective, anti-oxidative, anti-ulcer, antidepressant, anti-septicaemic or anti-inflammatory activities. All these applications and properties of polysaccharides are for the first time compiled in a thorough and comprehensive overview in the present work. This reference work is organized thematically in four parts: Part I. Polysaccharides: Occurrence, Structure, Distribution and Biotechnology. Part II. Methods. Part III. Bioactive Polysaccharides. Part IV. Polysaccharides as Food. This authoritative reference work is edited by experienced experts, all chapters are written by well recognized international specialists. It is useful to all those working in the field of botany, phytochemistry, pharmacy, drug delivery, molecular biology, metabolomics, forestry, environment, conservation, biotechnology and NGOs working for forest protection.



Methods of Protein Separation

Methods of Protein Separation Author Nicholas Catsimpoolas
ISBN-10 9781475712575
Release 2013-04-18
Pages 281
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This open-end treatise on methods concerning protein separation had its beginning in an American Chemical Society symposium entitled "Con temporary Protein Separation Methods" which was held in Atlantic City, New Jersey in September 1974. The purpose of the symposium-and subse quently of the present work-was to review the available modern techniques and underlying principles for achieving one of the very important tasks of experimental biology, namely the separation and characterization of proteins present in complex biological mixtures. Physicochemical characterization was covered only as related to the parent method of fractionation and there fore involved mostly mass transport processes. Additionally, the presentation of methods for gaini. ng insight into complex interacting protein profiles was considered of paramount importance in the interpretation of separation patterns. Finally, specific categories of proteins (e. g. , chemically modified, deriving from a specific tissue, conjugated to different moieties, etc. ) require meticulous trial and selection andjor modification of existing methodology to carry out the desired separation. In such cases, the gained experience provides valuable guidelines for further experimentation. Although powerful techniques exist today for the separation and related physicochemical characterization of proteins, many biological fractionation problems require further innovations. It is hoped that the description in the present treatise of some of the available separation tools and their limitations will provide the necessary integrated background for new developments in this area.



Chaos and Complex Systems

Chaos and Complex Systems Author Stavros G. Stavrinides
ISBN-10 9783642339141
Release 2013-03-19
Pages 15
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Complexity Science and Chaos Theory are fascinating areas of scientific research with wide-ranging applications. The interdisciplinary nature and ubiquity of complexity and chaos are features that provides scientists with a motivation to pursue general theoretical tools and frameworks. Complex systems give rise to emergent behaviors, which in turn produce novel and interesting phenomena in science, engineering, as well as in the socio-economic sciences. The aim of all Symposia on Chaos and Complex Systems (CCS) is to bring together scientists, engineers, economists and social scientists, and to discuss the latest insights and results obtained in the area of corresponding nonlinear-system complex (chaotic) behavior. Especially for the “4th International Interdisciplinary Chaos Symposium on Chaos and Complex Systems,” which took place April 29th to May 2nd, 2012 in Antalya, Turkey, the scope of the symposium had been further enlarged so as to encompass the presentation of work from circuits to econophysics, and from nonlinear analysis to the history of chaos theory. The corresponding proceedings collected in this volume address a broad spectrum of contemporary topics, including but not limited to networks, circuits, systems, biology, evolution and ecology, nonlinear dynamics and pattern formation, as well as neural, psychological, psycho-social, socio-economic, management complexity and global systems.



Nanobiomaterials

Nanobiomaterials Author Xiumei Wang
ISBN-10 9783527698653
Release 2017-11-21
Pages 238
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Written by an international team of editors and contributors from renowned universities and institutes, this book addresses the latest research in the field of nanobiomaterials, covering nanotechnologies for their fabrication, developments in biomedical applications, and the challenges of biosafety in clinic uses. Clearly structured, the volume defines the scope and classification of the field, resulting in a broad overview from fundamental principles to current technological advances, and from materials synthesis to biomedical applications along with future trends.



Economic Botany

Economic Botany Author G.E. Wickens
ISBN-10 9789401009690
Release 2012-12-06
Pages 535
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The strength of this book is that it is written by someone who has spent a lifetime devoted to the science of economic botany. The author has brought together his vast experience in the field in Africa with his studies of arid land plants at the Royal Botanic Gardens, Kew. The result is an informative and reliable text that covers a vast range of topics. It is also firmly based upon the author's research and interest in plant taxonomy and therefore fully acknowledges the importance of correct naming and classification in the field of science of economic botany. The coverage is of economic botany in its broadest sense. I was delighted to find such topics as ecophysiology, plant breeding, the environment and conservation are included in the text. This gives the book a much more comprehensive coverage than most other texts on the subject. I was also glad to see that the book covers the use of various organisms that are no longer considered part of the plant kingdom such as various species of fungi and algae. It is indeed a broad ranging book that will be of use to many people interested in the uses of plants and fungi. Economic botany is once again being given more prominence as a discipline because of its enormous relevance to both conservation and sustainable development. Those people involved in those topics shOUld find this a most useful resource.



Antimicrobial Resistance in Developing Countries

Antimicrobial Resistance in Developing Countries Author Aníbal de J. Sosa
ISBN-10 0387893709
Release 2009-10-08
Pages 554
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Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and crops from a short growing season. Waterborne infections were averted by owning your own well or supporting a community reservoir. Everyone got vaccines in rich countries, while people in others got them later if at all. Antimicrobial agents seemed at first to be an exception. They did not need to be delivered through a cold chain and to everyone, as vaccines did. They had to be given only to infected patients and often then as relatively cheap injectables or pills off a shelf for only a few days to get astonishing cures. Antimicrobials not only were better than most other innovations but also reached more of the world’s people sooner. The problem appeared later. After each new antimicrobial became widely used, genes expressing resistance to it began to emerge and spread through bacterial populations. Patients infected with bacteria expressing such resistance genes then failed treatment and remained infected or died. Growing resistance to antimicrobial agents began to take away more and more of the cures that the agents had brought.



Advances in QSAR modeling

Advances in QSAR modeling Author Kunal Roy
ISBN-10 9783319568508
Release 2017-06-29
Pages 555
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The book covers theoretical background and methodology as well as all current applications of Quantitative Structure-Activity Relationships (QSAR). Written by an international group of recognized researchers, this edited volume discusses applications of QSAR in multiple disciplines such as chemistry, pharmacy, environmental and agricultural sciences addressing data gaps and modern regulatory requirements. Additionally, the applications of QSAR in food science and nanoscience have been included – two areas which have only recently been able to exploit this versatile tool. This timely addition to the series is aimed at graduate students, academics and industrial scientists interested in the latest advances and applications of QSAR.



Nanomedicine for Cancer Therapy

Nanomedicine for Cancer Therapy Author Piyush Kumar
ISBN-10 9783319458267
Release 2016-11-21
Pages 68
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This Brief focuses on the cancer therapy available till date, from conventional drug delivery to nanomedicine in clinical trial. In addition, it reports on future generation based nanotherapeutics and cancer theranostic agent for effective therapeutic diagnosis and treatment. Breast cancer was chosen as the model system in this review. The authors give emphasis to multiple drug resistance (MDR) and its mechanism and how to overcome it using the nanoparticle approach.



On the Power of Fuzzy Markup Language

On the Power of Fuzzy Markup Language Author Giovanni Acampora
ISBN-10 9783642354885
Release 2012-12-14
Pages 188
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One of the most successful methodology that arose from the worldwide diffusion of Fuzzy Logic is Fuzzy Control. After the first attempts dated in the seventies, this methodology has been widely exploited for controlling many industrial components and systems. At the same time, and very independently from Fuzzy Logic or Fuzzy Control, the birth of the Web has impacted upon almost all aspects of computing discipline. Evolution of Web, Web2.0 and Web 3.0 has been making scenarios of ubiquitous computing much more feasible; consequently information technology has been thoroughly integrated into everyday objects and activities. What happens when Fuzzy Logic meets Web technology? Interesting results might come out, as you will discover in this book. Fuzzy Mark-up Language is a son of this synergistic view, where some technological issues of Web are re-interpreted taking into account the transparent notion of Fuzzy Control, as discussed here. The concept of a Fuzzy Control that is conceived and modeled in terms of a native web wisdom represents another step towards the last picture of Pervasive Web Intelligence.



Design of Nanostructures for Versatile Therapeutic Applications

Design of Nanostructures for Versatile Therapeutic Applications Author Alexandru Mihai Grumezescu
ISBN-10 9780128136683
Release 2018-02-03
Pages 690
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Design of Nanostructures for Versatile Therapeutic Applications focuses on antimicrobial, antioxidant and nutraceutical applications of nanostructured materials. Many books discuss these subjects, but not from a pharmaceutical point-of-view. This book covers novel approaches related to the modulation of microbial biofilms, antimicrobial therapy and encapsulate polyphenols as antioxidants. Written by an internationally diverse group of academics, this book is an important reference resource for researchers, both in biomaterials science and the pharmaceutical industry. Assesses the most recently developed nanostructures that have potential antimicrobial properties, explaining their novel mechanical aspects Shows how nanoantibiotics can be used to more effectively treat disease Provides a cogent summary of recent developments in nanoantimicrobial discovery, allowing readers to quickly familiarize themselves with the topic



Computers in Fisheries Research

Computers in Fisheries Research Author Bernard A. Megrey
ISBN-10 9781402086366
Release 2008-11-26
Pages 422
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The first edition of this book was published by Chapman and Hall Ltd. in 1996. The first edition contained nine chapters and, for all except one chapter, the original chapter authors agreed to update their chapter. Comparing these chapters gives the reader an idea of the development over a time span of more than 10 years between the two editions. In the preparation of the second edition we decided to add more chapters reflecting some important fields with significant contributions to present day fishery research. These are the use of internet for searching of information (Chapter 2), and the present state and use of remote sensing (Chapter 5), ecosystem modeling (Chapter 8) and visualization of data (Chapter 10). This second edition provides a valuable sampling of contemporary applications. Scientists have an opportunity to evaluate the suitability of different computer technology applications to their particular research situation thereby taking advantage of the experience of others. The chapters that follow are the fruition of this idea. The history behind this book started in 1989 when we were asked by Dr. Vidar Wespestad (previously: Alaska Fisheries Science Center, Seattle, USA) to prepare and convene a session at the 1992 World Fishery Congress in Athens, Greece on computer applications in fisheries. We agreed that the idea was a good one and the computer session in 1992 turned out to be very successful.