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Interferon

Interferon Author Toine Pieters
ISBN-10 9781134293056
Release 2005-03-15
Pages 284
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This innovative study charts the beginnings, history and fate of Interferon - one of modern medicine's most famous and infamous drugs. Interferon is part of the medical profession's armoury against viral infection, cancer and MS. The story of its development and use is one of survival in the face of remarkable cycles of promise and disappointment as a miracle drug. By telling this story, Toine Pieters' book provides insight into the research, manufacture, and marketing of new bio-molecules that mark modern medical science. Pieters' closely argued book adopts a multi-disciplinary approach in seeking to trace the extraordinary voyage of interferon. Through the lens of interferon's voyage, the book explores the interaction of the broad range of actors driving medical science: *biological and clinical researchers *the pharmaceutical industry *high-powered government agencies *doctors and patients *the media. The book demonstrates how research on interferon led to new clinical definitions of cancer and a new rationale for therapeutic use of the drug. Interferon provides a marvellous insight into the development of one of the most controversial drugs of our time. It enhances our understanding of how medicine manufacture and marketing all played a part in pushing back the boundaries of research, from the post-penicillin era to the genetics revolution in medicine. This study is of particular interest to undergraduates and postgraduates in the fields of History of Medicine, Pharmacology, Medical Genetics and History of Science.



Selling Science

Selling Science Author Stephen E. Mawdsley
ISBN-10 9780813574417
Release 2016-08
Pages 232
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Today, when many parents seem reluctant to have their children vaccinated, even with long proven medications, the Salk vaccine trial, which enrolled millions of healthy children to test an unproven medical intervention, seems nothing short of astonishing. In Selling Science, medical historian Stephen E. Mawdsley recounts the untold story of the first large clinical trial to control polio using healthy children—55,000 healthy children—revealing how this long-forgotten incident cleared the path for Salk’s later trial. Mawdsley describes how, in the early 1950s, Dr. William Hammon and the National Foundation for Infantile Paralysis launched a pioneering medical experiment on a previously untried scale. Conducted on over 55,000 healthy children in Texas, Utah, Iowa, and Nebraska, this landmark study assessed the safety and effectiveness of a blood component, gamma globulin, to prevent paralytic polio. The value of the proposed experiment was questioned by many prominent health professionals as it harbored potential health risks, but as Mawdsley points out, compromise and coercion moved it forward. And though the trial returned dubious results, it was presented to the public as a triumph and used to justify a federally sanctioned mass immunization study on thousands of families between 1953 and 1954. Indeed, the concept, conduct, and outcome of the GG study were sold to health professionals, medical researchers, and the public at each stage. At a time when most Americans trusted scientists, their mutual encounter under the auspices of conquering disease was shaped by politics, marketing, and at times, deception. Drawing on oral history interviews, medical journals, newspapers, meeting minutes, and private institutional records, Selling Science sheds light on the ethics of scientific conduct, and on the power of marketing to shape public opinion about medical experimentation.



Healthcare in Private and Public from the Early Modern Period to 2000

Healthcare in Private and Public from the Early Modern Period to 2000 Author Paul Weindling
ISBN-10 9781317578307
Release 2014-12-17
Pages 258
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A key volume on a central aspect of the history of medicine and its social relations, The History of Healthcare in Public and Private examines how the modernisation of healthcare resulted in a wide variety of changing social arrangements in both public and private spheres. This book considers a comprehensive range of topics ranging from children's health, mental disorders and the influence of pharmaceutical companies to the systems of twentieth century healthcare in Britain, Eastern Europe and South Africa. Covering a broad chronological, thematic and global scope, chapters discuss key themes such as how changing economies have influenced configurations of healthcare, how access has varied according to lifecycle, ethnicity and wealth, and how definitions of public and private have shifted over time. Containing illustrations and a general introduction that outlines the key themes discussed in the volume, The History of Healthcare in Public and Private is essential reading for any student interested in the history of medicine.



Bulletin of the History of Medicine

Bulletin of the History of Medicine Author
ISBN-10 NWU:35556037545159
Release 2006
Pages
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Includes the Transactions of the 15th- annual meetings of the American Association of the History of Medicine, 1939-



Science Technology and Medicine in the Modern Japanese Empire

Science  Technology  and Medicine in the Modern Japanese Empire Author David G. Wittner
ISBN-10 9781317444367
Release 2016-03-22
Pages 290
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Science, technology, and medicine all contributed to the emerging modern Japanese empire and conditioned key elements of post-war development. As the only emerging non-Western country that was a colonial power in its own right, Japan utilized these fields not only to define itself as racially different from other Asian countries and thus justify its imperialist activities, but also to position itself within the civilized and enlightened world with the advantages of modern science, technologies, and medicine. This book explores the ways in which scientists, engineers and physicians worked directly and indirectly to support the creation of a new Japanese empire, focussing on the eve of World War I and linking their efforts to later post-war developments. By claiming status as a modern, internationally-engaged country, the Japanese government was faced with having to control pathogens that might otherwise not have threatened the nation. Through the use of traditional and innovative techniques, this volume shows how the government was able to fulfil the state’s responsibility to protect society to varying degrees. The contributors push the field of the history of science, technology and medicine in Japan in new directions, raising questions about the definitions of diseases, the false starts in advancing knowledge, and highlighting the very human nature of fields which, on the surface, seem to non-specialists to be highly rational. Challenging older interpretative tendencies, this book highlights the vigour of the field and the potential for future development. Therefore, it will be of huge interest to students and scholars of Japanese history, Asian history, the history of science and technology and the history of medicine.



Regulating Pharmaceuticals In Europe Striving For Efficiency Equity And Quality

Regulating Pharmaceuticals In Europe  Striving For Efficiency  Equity And Quality Author Mossialos, Elias
ISBN-10 9780335226559
Release 2004-06-01
Pages 390
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The rising cost of pharmaceutical expenditures in many European countries is of concern to governments required to make effective use of health care budgets. Taking a broad perspective that encompasses institutional, political and supranational aspects of pharmaceutical regulation, this book examines approaches used to manage pharmaceutical expenditure across Europe and what impact these strategies have had on efficiency, quality, equity and cost of pharmaceutical care. Regulating Pharmaceuticals in Europe is an important book for students of health policy, regulation and management, and for health managers and policy makers.



Drug Discovery

Drug Discovery Author Walter Sneader
ISBN-10 9780470015520
Release 2005-10-31
Pages 472
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Written by a leading authority with an excellent reputation and ability for writing a good narrative, Drug Discovery: A History is a far cry from simply a list of chemical structures. This lively new text considers the origins, development and history of medicines that generate high media interest and have a huge social and economic impact on society. Set within a wide historical, social and cultural context, it provides expanded coverage of pre-twentieth century drugs, the huge advances made in the twentieth century and the latest developments in drug research. Hallmark features: Up-to-the-minute information in drug research Vignettes of special and unusual information, and anecdotes Discusses drug prototypes from all sources More comprehensive than other volumes on history of drug discovery From the reviews: "...an excellent bibliographic resource for those interested in the background papers that serve as the foundation for discovery of specific drug entities." JOURNAL OF MEDICAL CHEMISTRY, June 2006 "...a very comprehensive overview of drug development. It should be on the shelf on any aspiring pharmacist, medicinal chemist, or person interested in the history of therapeutic agents." JOURNAL OF CHEMICAL EDUCATION, February 2006 "...a very readable and closely researched book..." CHEMISTRY & INDUSTRY, October 2005



Impure Science

Impure Science Author Steven Epstein
ISBN-10 9780520214453
Release 1998-09-15
Pages 466
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Epstein shows the extent to which AIDS research has been a social and political phenomenon and how the AIDS movement has transformed biomedical research practices through its capacity to garner credibility by novel strategies.



Pharmacy Practice

Pharmacy Practice Author Kevin M. G. Taylor
ISBN-10 9780203303153
Release 2003-09-02
Pages 561
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Today's pharmaceutical services are patient-oriented rather than drug-oriented. This shift towards patient-centred care comes at a time when healthcare is delivered by an integrated team of health workers. Effective pharmacy practice requires an understanding of the social context within which pharmacy is practised, recognising the particular needs and circumstances of the users of pharmaceutical services and of pharmacy's place within health service provision. Designed for undergraduate and postgraduate pharmacists, Pharmacy Practice provides a background to the social context of pharmacy including: * the development of pharmacy practice * international dimensions of pharmacy practice * health, illness, and medicines use * professional practice * meeting the pharmaceutical care needs of specific populations * measuring and regulating medicines use * research methods, evaluation, audit and clinical governance



Deadly Medicines and Organised Crime

Deadly Medicines and Organised Crime Author Peter Gotzsche
ISBN-10 1138443476
Release 2017-06-30
Pages
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Deadly Medicines and Organised Crime has been writing in one form or another for most of life. You can find so many inspiration from Deadly Medicines and Organised Crime also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Deadly Medicines and Organised Crime book for free.



Vaccinations and Public Concern in History

Vaccinations and Public Concern in History Author Andrea Kitta
ISBN-10 9781136577086
Release 2012-01-30
Pages 184
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Vaccinations and Public Concern in History explores vernacular beliefs and practices that surround decisions not to vaccinate. Through the use of ethnographic, media, and narrative analyses, this book explores the vernacular explanatory models used in inoculation decision-making. The research on which the book draws was designed to help create public health education programs and promotional materials that respond to patients’ fears, understandings of risk, concerns, and doubts. Exploring the nature of inoculation distrust and miscommunication, Dr. Andrea Kitta identifies areas that require better public health communication and greater cultural sensitivity in the handling of inoculation programs.



The Cure Within A History of Mind Body Medicine

The Cure Within  A History of Mind Body Medicine Author Anne Harrington
ISBN-10 0393071081
Release 2009-02-16
Pages 354
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"A splendid history of mind-body medicine...a book that desperately needed to be written." —Jerome Groopman, New York Times Is stress a deadly disease on the rise in modern society? Can mind-body practices from the East help us become well? When it comes to healing, we believe we must look beyond doctors and drugs; we must look within ourselves. Faith, relationships, and attitude matter. But why do we believe such things? From psychoanalysis to the placebo effect to meditation, this vibrant cultural history describes mind-body healing as rooted in a patchwork of stories, allowing us to make new sense of our suffering and to rationalize new treatments and lifestyles.



Molecularizing Biology and Medicine

Molecularizing Biology and Medicine Author Soraya de Chadarevian
ISBN-10 9781135298012
Release 2003-09-02
Pages 292
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The contributors present a coherent set of case studies of practices, technologies and strategies aimed at the isolation, investigation, manipulation, production, and uses of molecules including vitamins, hormones, blood products, antibiotics, and vaccines. These case studies examine how processes of molecularization were set in motion in the inter-war period, how they were used as a resource in the biomedical 'mobilization' of World War II, and how new alliances and strategies created as part of the war effort played a central role in the reorganisation of biomedicine in the post-war period.



A Clinical Guide to the Treatment of the Human Stress Response

A Clinical Guide to the Treatment of the Human Stress Response Author George S. Everly, Jr.
ISBN-10 9781461455387
Release 2012-12-13
Pages 488
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This new edition emphasizes the unique contribution of this longstanding text in the integration of mind/body relationships. The concept of stress, as defined and elaborated in Chapter 1, the primary efferent biological mechanisms of the human stress response, as described in Chapter 2, and the link from stress arousal to disease, as defined in Chapter 3, essentially remains the same. However, updates in microanatomy, biochemistry and tomography are added to these chapters. All other chapters will be updated as well, as there has been significant changes in the field over the past eight years.



Biomedicine and the Human Condition

Biomedicine and the Human Condition Author Michael G. Sargent
ISBN-10 1139443933
Release 2005-02-28
Pages
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How to avoid disease, how to breed successfully and how to live to a reasonable age, are questions that have perplexed mankind throughout history. This 2005 book explores our progress in understanding these challenges, and the risks and rewards of our attempts to find solutions. From the moment of conception, nutrition and exposure to microbes or alien chemicals have consequences that are etched into our cells and genomes. Such events have a crucial impact on development in utero and in childhood, and later, on the way we age, respond to infection, or the likelihood of developing chronic diseases, including cancer. The issues covered include the powerful influence of infectious disease on human society, the burden of our genetic legacy and the lottery of procreation. The author discusses how prospects for human life might continually improve as biomedicine addresses these problems and also debates the ethical checkpoints encountered.



Classical Genetic Research and Its Legacy

Classical Genetic Research and Its Legacy Author Jean-Paul Gaudillière
ISBN-10 9781134334155
Release 2004-10-07
Pages 256
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With the rise of genomics, the life sciences have entered a new era. This book provides a comprehensive history of mapping procedures as they were developed in classical genetics. An accompanying volume - From Molecular Genetics to Genomics - covers the history of molecular genetics and genomics. The book shows that the technology of genetic mapping is by no means a recent acquisition of molecular genetics or even genetic engineering. It demonstrates that the development of mapping technologies has accompanied the rise of modern genetics from its very beginnings. In Section One, Mendelian genetics is set in perspective from the viewpoint of the detection and description of linkage phenomena. Section Two addresses the role of mapping for the experimental working practice of classical geneticists, their social interactions and for the laboratory 'life worlds'. With detailed analyses of the scientific practices of mapping and its illustration of the diversity of mapping practices this book is a significant contibution to the history of genetics. A companion volume from the same editors - From Molecular Genetics to Genomics: The Mapping Cultures of Twentieth Century Genetics - covers the history of molecular genetics and genomics.



Protecting the Health of the Poor

Protecting the Health of the Poor Author Abraar Karan
ISBN-10 9781783605552
Release 2015-12-15
Pages 312
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Nowhere is the injustice of the global distribution of income and wealth more palpable than in health. While the world’s affluent spend fortunes on the most trifling treatments, poor people’s lives are ruined and often cut short prematurely by challenges that could easily be overcome at low cost: childbirth, diarrhoea, malnutrition, malaria, HIV/AIDS, measles, pneumonia. Millions are avoidably dying from such causes each year and billions of lives avoidably blighted by these diseases of poverty. Drawing on in-depth empirical research spanning Asia, Latin America, and Africa, this path-breaking collection offers fresh perspectives from critically engaged scholars. Protecting the Health of the Poor presents a call and a vision for unified efforts across geographies, levels and sectors to make the right to health truly universal.