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Lab on a Chip Devices and Micro Total Analysis Systems

Lab on a Chip Devices and Micro Total Analysis Systems Author Jaime Castillo-León
ISBN-10 9783319086873
Release 2014-11-05
Pages 243
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This book covers all the steps in order to fabricate a lab-on-a-chip device starting from the idea, the design, simulation, fabrication and final evaluation. Additionally, it includes basic theory on microfluidics essential to understand how fluids behave at such reduced scale. Examples of successful histories of lab-on-a-chip systems that made an impact in fields like biomedicine and life sciences are also provided. This book also: · Provides readers with a unique approach and toolset for lab-on-a-chip development in terms of materials, fabrication techniques, and components · Discusses novel materials and techniques, such as paper-based devices and synthesis of chemical compounds on-chip · Covers the four key aspects of development: basic theory, design, fabrication, and testing · Provides readers with a comprehensive list of the most important journals, blogs, forums, and conferences where microfluidics and lab-on-a-chip news, methods, techniques and challenges are presented and discussed, as well as a list of companies providing design and simulation support, components, and/or developing lab-on-a-chip and microfluidic devices.



Separation Methods In Microanalytical Systems

Separation Methods In Microanalytical Systems Author Jorg P. Kutter
ISBN-10 9781420027938
Release 2005-09-09
Pages 592
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Focusing on what has been one of the driving forces behind the development of lab-on-a-chip devices, Separation Methods in Microanalytical Systems explores the implementation, realization, and operation of separation techniques and related complex workflows on microfabricated devices. The book details the design, manufacture, and integration of diverse components needed to perform an entire analytical procedure on a single miniaturized device. The content applies to a diversity of disciplines including chemical analysis, biomedical diagnostics, environmental monitoring, and drug discovery. Separation Methods in Microanalytical Systems lays its theoretical background in a way that scientists from varied disciplines can approach. The book describes factors that influence the performance of separation, such as microfluidic handling, sample pre-treatment, and detection. It also conveys fabrication and material issues, design challenges, and practical considerations. Several chapters describe specific separation techniques that are central to micro-Total Analysis Systems (μ-TAS) as well as novel methods and emerging trends in microchip-based separations. The book also provides an applications overview that supplies a wealth of examples that help scientists put their ideas in perspective with already existing solutions. This multi-authored volume offers different styles, approaches, and opinions for a given problem, reflecting the various angles researchers take to handle the same issues. A one-stop guide for understanding, designing, and working with separation techniques in microanalytical devices, Separation Methods in Microanalytical Systems is a valuable reference for scientists and engineers already preparing to meet the anticipated demand for function-specific chemical separation systems.



Cardiac Cell Culture Technologies

Cardiac Cell Culture Technologies Author Zbigniew Brzozka
ISBN-10 9783319706856
Release 2017-11-21
Pages 234
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This book provides an introduction to the biological background of heart functioning and analyzes the various materials and technologies used for the development of microfluidic systems dedicated to cell culture, with an emphasis on cardiac cells. The authors describe the characterization of microfluidic systems for cardiac cell culture and center their discussion of the use of stem cell stimulation based on four different types: electrical, biochemical, physical, and mechanical. This book is appropriate for researchers focused on on-chip technologies and heart studies, students in bioengineering and microengineering courses, and a variety of professionals, such as biotechnologists, biomedical engineers, and clinicians working in the cardiac diseases field.



Bionanotechnology II

Bionanotechnology II Author David E. Reisner
ISBN-10 9781439804636
Release 2011-08-25
Pages 583
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The impact and importance of nanotechnology continues to grow, and nanomedicine and biotechnology have become areas of increased development. Biomedical engineers who work with biological processes and structures must have a deeply rooted understanding of the role of bionanotechnology, a rapidly evolving sector of the nanotechnology field. Bionanotechnology II: Global Prospects, a follow-up to the editor’s highly successful first volume, contains 26 entirely new contributions that provide a broad survey of research shaping this critical field. With coverage of technical and nontechnical areas, the book offers representative reporting on a wide variety of activity from around the world. It discusses the role of nanotechnology in novel medical devices, bioanalytical technologies, and nanobiomaterials. Topics discussed include: Emerging microscale technologies Bionanotech-based water treatment Tissue engineering and drug delivery Antimicrobial nanomaterials in the textile industry Bionanotechnology applications in plants and agriculture With contributions from researchers in Israel, Egypt, Iran, Jordan, Singapore, South Africa, Turkey, Thailand, Argentina, the United Kingdom, and the United States, this volume presents a worldwide perspective on some of the critical areas shaping bionanotechnology today.



Bioanalytics

Bioanalytics Author Friedrich Lottspeich
ISBN-10 9783527694440
Release 2018-03-08
Pages 450
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Analytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids. The presentation includes frequent cross-references in order to highlight the many connections between different techniques. The book provides a birdï¿1⁄2s eye view of the entire subject and enables the reader to select the most appropriate method for any given bioanalytical challenge. This makes the book a handy resource for students and researchers in setting up and evaluating experimental research. The depth of the analysis and the comprehensive nature of the coverage mean that there is also a great deal of new material, even for experienced experimentalists. The following techniques are covered in detail: - Purification and determination of proteins - Measuring enzymatic activity - Microcalorimetry - Immunoassays, affinity chromatography and other immunological methods - Cross-linking, cleavage, and chemical modification of proteins - Light microscopy, electron microscopy and atomic force microscopy - Chromatographic and electrophoretic techniques - Protein sequence and composition analysis - Mass spectrometry methods - Measuring protein-protein interactions - Biosensors - NMR and EPR of biomolecules - Electron microscopy and X-ray structure analysis - Carbohydrate and lipid analysis - Analysis of posttranslational modifications - Isolation and determination of nucleic acids - DNA hybridization techniques - Polymerase chain reaction techniques - DNA sequence and epigenetic modification analysis - Analysis of protein-nucleic acid interactions - Analysis of sequence data - Proteomics, metabolomics, peptidomics and toponomics - Chemical biology



Biomedical Microsystems

Biomedical Microsystems Author Ellis Meng
ISBN-10 9781439894521
Release 2010-09-29
Pages 408
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Poised to dramatically impact human health, biomedical microsystems (bioMEMS) technologies incorporate various aspects from materials science, biology, chemistry, physics, medicine, and engineering. Reflecting the highly interdisciplinary nature of this area, Biomedical Microsystems covers the fundamentals of miniaturization, biomaterials, microfabrication, and nanotechnology, along with relevant applications. Written by an active researcher who was recently named one of Technology Review’s Young Innovators Under 35, the book begins with an introduction to the benefits of miniaturization. It then introduces materials, fabrication technology, and the necessary components of all bioMEMS. The author also covers fundamental principles and building blocks, including microfluidic concepts, lab-on-a-chip systems, and sensing and detection methods. The final chapters explore several important applications of bioMEMS, such as microdialysis, catheter-based sensors, MEMS implants, neural probes, and tissue engineering. For readers with a limited background in MEMS and bioMEMS, this book provides a practical introduction to the technology used to make these devices, the principles that govern their operation, and examples of their application. It offers a starting point for understanding advanced topics and encourages readers to begin to formulate their own ideas about the design of novel bioMEMS. A solutions manual is available for instructors who want to convert this reference to classroom use.



Microfabrication for Industrial Applications

Microfabrication for Industrial Applications Author Regina Luttge
ISBN-10 9780815519775
Release 2011-08-31
Pages 312
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This book focuses on the industrial perspective for micro- and nanofabrication methods including large-scale manufacturing, transfer of concepts from lab to factory, process tolerance, yield, robustness, and cost. It gives a history of miniaturization, micro- and nanofabrication, and surveys industrial fields of application, illustrating fabrication processes of relevant micro and nano devices. Concerning sub-micron feature manufacture, the book explains: the philosophy of micro/ nanofabrication for integrated circuit industry; thin film deposition; (waveguide, plastic, semiconductor) material processing; packaging; interconnects; stress (e.g., thin film residual); economic; and environmental aspects. Micro/nanomechanical sensors and actuators are explained in depth with information on applications, materials (incl. functional polymers), methods, testing, fabrication, integration, reliability, magnetic microstructures, etc. Shows engineers & students how to evaluate the potential value of current and nearfuture manufacturing processes for miniaturized systems in industrial environments Explains the top-down and bottom up approaches to nanotechnology, nanostructures fabricated with beams, nano imprinting methods, nanoparticle manufacturing (and their health aspects), nanofeature analysis, and connecting nano to micro to macro Discusses issues for practical application cases; possibilities of dimension precision; large volume manufacturing of micro- & nanostructures (machines, materials, costs) Explains applications of Microsystems for information technology, e.g.: data recording (camera, microphone), storage (memories, CDs), communication; computing; and displays (beamers, LCD, TFT) Case studies are given for sensors, resonators, probes, transdermal medical systems, micro- pumps & valves, inkjets, DNA-analysis, lab-on-a-chip, & micro-cooling



Lab on a Chip Technology Biomolecular separation and analysis

Lab on a Chip Technology  Biomolecular separation and analysis Author K. E. Herold
ISBN-10 9781904455479
Release 2009
Pages 300
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No further information has been provided for this title.



Micro Total Analysis Systems 2004

Micro Total Analysis Systems 2004 Author
ISBN-10 CHI:66267438
Release 2004
Pages 724
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The Eighth International Conference on Miniaturized Systems in Chemistry and Life Science - MicroTas 2004 - is an annual meeting focusing on the research, development and application of miniaturized technologies and methodologies in chemistry and life science. The conference is celebrating its tenth anniversary after the first workshop at the University of Twente, The Netherlands in 1994. This research field is rapidly developing and changing towards a domain where core competence areas such as microfluidics, micro- and nanotechnology, materials science, chemistry, biology, and medicine are melting together to a truly interdisciplinary meeting place. This volume is the first in a two volume set, a valuable reference collection to all working in this field.



Electrochemical Sensors Biosensors and their Biomedical Applications

Electrochemical Sensors  Biosensors and their Biomedical Applications Author Xueji Zhang
ISBN-10 008055489X
Release 2011-04-28
Pages 616
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This book broadly reviews the modem techniques and significant applications of chemical sensors and biosensors. Chapters are written by experts in the field – including Professor Joseph Wang, the most cited scientist in the world and renowned expert on sensor science who is also co-editor. Each chapter provides technical details beyond the level found in typical journal articles, and explores the application of chemical sensors and biosensors to a significant problem in biomedical science, also providing a prospectus for the future. This book compiles the expert knowledge of many specialists in the construction and use of chemical sensors and biosensors including nitric oxide sensors, glucose sensors, DNA sensors, hydrogen sulfide sensors, oxygen sensors, superoxide sensors, immuno sensors, lab on chip, implatable microsensors, et al. Emphasis is laid on practical problems, ranging from chemical application to biomedical monitoring and from in vitro to in vivo, from single cell to animal to human measurement. This provides the unique opportunity of exchanging and combining the expertise of otherwise apparently unrelated disciplines of chemistry, biological engineering, and electronic engineering, medical, physiological. Provides user-oriented guidelines for the proper choice and application of new chemical sensors and biosensors Details new methodological advancements related to and correlated with the measurement of interested species in biomedical samples Contains many case studies to illustrate the range of application and importance of the chemical sensors and biosensors



In Vitro Diagnostic Devices

In Vitro Diagnostic Devices Author Chao-Min Cheng
ISBN-10 9783319197371
Release 2015-07-16
Pages 106
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Addressing the origin, current status, and future development of point-of-care diagnostics, and serving to integrate knowledge and tools from Analytical Chemistry, Bioengineering, Biomaterials, and Nanotechnology, this book focusses on addressing the collective and combined needs of industry and academia (including medical schools) to effectively conduct interdisciplinary research. In addition to summarizing and detailing developed diagnostic devices, this book will attempt to point out the possible future trends of development for point-of-care diagnostics using both scientifically based research and practical engineering needs with the aim to help novices comprehensively understand the development of point-of-care diagnostics. This includes demonstrating several common but critical principles and mechanisms used in point-of-care diagnostics that address practical needs (e.g., disease or healthcare monitoring) using two well-developed examples so far: 1) blood glucose meters (via electrochemistry); and, 2) pregnancy tests (via lateral flow assay). Readers of this book will come to fully comprehend how to develop point-of-care diagnostics devices, and will be inspired to contribute to a critical global cause – the development of inexpensive, effective, and portable in vitro diagnostics tools (for any purpose) that can be used either at home or in resource limited areas.



Proceedings

Proceedings Author
ISBN-10 UIUC:30112060208219
Release 2003
Pages
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Proceedings has been writing in one form or another for most of life. You can find so many inspiration from Proceedings also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Proceedings book for free.



Lab on a Chip Technology Fabrication and microfluidics

Lab on a Chip Technology  Fabrication and microfluidics Author K. E. Herold
ISBN-10 9781904455462
Release 2009
Pages 409
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Lab-on-a-Chip (LOC) devices integrate and scale down laboratory functions and processes to a miniaturized chip format. Many LOC devices are used in a wide array of biomedical and other analytical applications including rapid pathogen detection, clinical diagnosis, forensic science, electrophoresis, flow cytometry, blood chemistry analysis, protein analysis, and DNA analysis. LOC devices can be fabricated from many types of material including various polymers, glass, or silicon - or combinations of these materials. A broad variety of fabrication technologies are used for LOC device fabrication. LOC systems have several common features including microfluidics and sensing capabilities. Microfluidics deals with fluid flow in tiny channels using flow control devices (e.g. channels, pumps, mixers, and valves). Sensing capabilities, usually optical or electrochemical sensors, can also be integrated into the chip. This invaluable book describes the latest methods and novel technologies being developed for the fabrication of LOC devices and the new approaches for fluid control and manipulation. Expert authors from around the world describe and discuss the newest technologies for the prototyping of devices, including replication and direct machining methods of fabrication. Part I of the book covers all aspects of fabrication including laser micromachining, silicon and glass micromachining, PMMA and COC microfluidic substrates, and xurography (LOC prototyping with a cutting plotter). Part II focuses on fluid control and manipulation for LOC systems. As well as providing examples of the use of pumps in microfluidics, the topics covered include electrokinetic pumping (electroosmois), electrochemical pumping and electrowetting, and the fabrication of a microchip for rapid polymerase chain reaction (PCR). This comprehensive volume presents the current technologies in the field and includes theoretical and technical information to enable both the understanding of the technology and the reproduction of experiments. The book will help the reader to understand current LOC technologies, to perform similar experiments, to design new LOC systems, and to develop new methodologies and applications. It is an essential book for biologists and clinicians using LOC technology and developing applications and also for engineering, chemical, and physical science researchers developing analytical technologies. It will also be useful as a teaching tool for bioengineering, biomedical engineering, and biology.



Technical Digest

Technical Digest Author Institute of Electrical and Electronics Engineers
ISBN-10 0780377443
Release 2003
Pages 711
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Technical Digest has been writing in one form or another for most of life. You can find so many inspiration from Technical Digest also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Technical Digest book for free.



Encyclopedia of Microfluidics and Nanofluidics

Encyclopedia of Microfluidics and Nanofluidics Author Dongqing Li
ISBN-10 9780387324685
Release 2008-08-06
Pages 2226
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Covering all aspects of transport phenomena on the nano- and micro-scale, this encyclopedia features over 750 entries in three alphabetically-arranged volumes including the most up-to-date research, insights, and applied techniques across all areas. Coverage includes electrical double-layers, optofluidics, DNC lab-on-a-chip, nanosensors, and more.



Sensors Handbook

Sensors Handbook Author Sabrie Soloman
ISBN-10 9780071605717
Release 2009-08-05
Pages 800
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Complete, State-of-the-Art Coverage of Sensor Technologies and Applications Fully revised with the latest breakthroughs in integrated sensors and control systems, Sensors Handbook, Second Edition provides all of the information needed to select the optimum sensor for any type of application, including engineering, semiconductor manufacturing, medical, military, agricultural, geographical, and environmental implementations. This definitive volume discusses a wide array of sensors, including MEMS, nano, microfabricated, CMOS, smart, NIR, SpectRx(tm), remote-sensing, fiber-optic, light, ceramic, and silicon sensors. Several in-depth application examples from a variety of industries are included. The comprehensive details in this authoritative resource enable you to accurately verify the specifications for any required component. This is the most through, up-to-date reference on sensing technologies available.



Microfluidic Technologies for Miniaturized Analysis Systems

Microfluidic Technologies for Miniaturized Analysis Systems Author Steffen Hardt
ISBN-10 9780387684246
Release 2007-09-29
Pages 616
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This book addresses Lab-on-a-Chip devices. It focuses on microfluidic technologies that have emerged in the past decade. Coverage presents a comprehensive listing of the most promising microfluidic technologies in the Lab-on-a-Chip field. It also details technologies that can be viewed as toolboxes needed to set up complex Lab-on-a-Chip systems.