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Life s Ratchet

Life s Ratchet Author Peter M. Hoffmann
ISBN-10 9780465022533
Release 2012
Pages 278
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A physicist describes how life emerges from the random motion of atoms through sophisticated cellular machinery and describes the long quest to determine the true nature of life from ancient Greece to the study of modern nanotechnology. 20,000 first printing.

Molecular Machines

Molecular Machines Author Benoît Roux
ISBN-10 9789814343466
Release 2011
Pages 288
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Molecular machines are complex biomolecules, proteins, nucleic acids, and carbohydrates that consume energy in order to perform specific functions. The concerted action of all those machines underlies all the activities of the living cell. To understand how such molecular machines are able to perform their function, it is necessary to identify the different moving parts and understand how they act together. Breaking new ground with these difficult problems is likely to require novel paradigms permitting a seamless integration of structural, dynamical and functional data from experiments and theory. The goal of this volume is to provide an introduction to the world of biological molecular machines to a broad audience of students and researchers in biosciences. Each chapter is written by leading experts to cover results from cutting-edge research, while remaining broadly accessible. The volume presents the current state of knowledge for several important systems, ranging from polymerases, the ribosome, chaperonins, the chromatophore, kinases, actin and myosin, membrane transporters, and voltage-gated ion channels, thus giving students and researches in biosciences a pedagogically integrated picture of this exciting and rapidly expanding field.

Brave Genius

Brave Genius Author Sean B. Carroll
ISBN-10 9780307952356
Release 2013-09-24
Pages 576
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The never-before-told account of the intersection of some of the most insightful minds of the 20th century, and a fascinating look at how war, resistance, and friendship can catalyze genius. In the spring of 1940, the aspiring but unknown writer Albert Camus and budding scientist Jacques Monod were quietly pursuing ordinary, separate lives in Paris. After the German invasion and occupation of France, both men joined the Resistance to help liberate the country from the Nazis, ascended to prominent, dangerous roles, and were very lucky to survive. After the war and through twists of circumstance, they became friends, and through their passionate determination and rare talent they emerged as leading voices of modern literature and biology, each receiving the Nobel Prize in his respective field. Drawing upon a wealth of previously unpublished and unknown material gathered over several years of research, Brave Genius tells the story of how Camus and Monod endured the most terrible episode of the twentieth century and then blossomed into remarkably creative and engaged individuals. It is a story of the transformation of ordinary lives into exceptional lives by extraordinary events—of courage in the face of overwhelming adversity, the flowering of creative genius, deep friendship, and profound concern for and insight into the human condition.


Wetware Author Dennis Bray
ISBN-10 9780300155440
Release 2009
Pages 267
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Wetware has been writing in one form or another for most of life. You can find so many inspiration from Wetware also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Wetware book for free.

What Is Life

What Is Life Author Addy Pross
ISBN-10 9780198784791
Release 2016-03-29
Pages 224
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Seventy years ago, Erwin Schrodinger posed a profound question: 'What is life, and how did it emerge from non-life?' This problem has puzzled biologists and physical scientists ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of 'systems chemistry' are unlocking the problem. Addy Pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life. Strikingly, he demonstrates that Darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle. The gulf between biology and the physical sciences is finally becoming bridged. This new edition includes an Epilogue describing developments in the concepts of fundamental forms of stability discussed in the book, and their profound implications. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.

Life Unfolding

Life Unfolding Author Jamie A. Davies
ISBN-10 9780199673537
Release 2014-02
Pages 299
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Tells the story of human development from egg to adult, showing how the understanding of how human beings come to be has been transformed in recent years.

Into the Cool

Into the Cool Author Eric D. Schneider
ISBN-10 9780226739366
Release 2005-06-01
Pages 362
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Demonstrates how the second law of thermodynamics--which refers to energy's tendency to change from being concentrated in one place to being spread out over time--is behind evolution, ecology, economics, and even the origins of life itself in this scientific tour de force that explores how complex systems emerge, enlarge, and reproduce in a chaotic world.

Cell Biology by the Numbers

Cell Biology by the Numbers Author Ron Milo
ISBN-10 9781317230694
Release 2015-12-01
Pages 400
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Very little in our human experience is truly comparable to the immensely crowded and bustling interior of a cell. Biological numeracy provides a new kind of understanding of the cellular world. This book brings together up-to-date quantitative data from the vast biological literature and uses the powerful tool of "back of the envelope" estimates to reveal fresh perspectives and insights from numbers commonly encountered in cell biology. Readers gain a feeling for the sizes, concentrations, energies, and rates that characterize the lives of cellsÑ thereby shedding new light on the microscopic realm.

Molecular Biology of Assemblies and Machines

Molecular Biology of Assemblies and Machines Author Alasdair C. Steven
ISBN-10 9781134982820
Release 2016-02-18
Pages 888
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Molecular Biology of Assemblies and Machines presents a comprehensive narrative describing the structures of macromolecular complexes and how they assemble and interact. Richly illustrated, it is written for advanced undergraduates, graduate students, and researchers in biochemistry, structural biology, molecular biology, biophysics, cell biology, and microbiology, and will also appeal to those in chemistry, immunology, and medicine. Essentially all major biological activities are performed by assemblies of macromolecules (proteins, RNA, and DNA) acting in concert. These assemblies are dynamic and many are endowed with machine-like properties. This unique book explores the molecular mechanisms employed at the critical level between individual macromolecules and cells and organelles.

Mathematical Ideas in Biology

Mathematical Ideas in Biology Author John Maynard Smith
ISBN-10 WISC:89036575694
Release 1968
Pages 152
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Mathematical Ideas in Biology has been writing in one form or another for most of life. You can find so many inspiration from Mathematical Ideas in Biology also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Mathematical Ideas in Biology book for free.

Chance and Necessity

Chance and Necessity Author Jacques Monod
ISBN-10 0140256466
Release 1997
Pages 198
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Change and necessity is a statement of Darwinian natural selection as a process driven by chance necessity, devoid of purpose or intent.

Atomic Evidence

Atomic Evidence Author David S. Goodsell
ISBN-10 9783319325101
Release 2016-08-04
Pages 182
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This book will take an evidence-based approach to current knowledge about biomolecules and their place in our lives, inviting readers to explore how we know what we know, and how current gaps in knowledge may influence the way we approach the information. Biomolecular science is increasingly important in our everyday life, influencing the choices we make about our diet, our health, and our wellness. Often, however, information about biomolecular science is presented as a list of immutable facts, discouraging critical thought. The book will introduce the basic tools of structural biology, supply real-life examples, and encourage critical thought about aspects of biology that are still not fully understood.

The Ballet of the Planets

The Ballet of the Planets Author Donald Benson
ISBN-10 9780199939299
Release 2012-05-11
Pages 192
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The Ballet of the Planets unravels the beautiful mystery of planetary motion, revealing how our understanding of astronomy evolved from Archimedes and Ptolemy to Copernicus, Kepler, and Newton. Mathematician Donald Benson shows that ancient theories of planetary motion were based on the assumptions that the Earth was the center of the universe and the planets moved in a uniform circular motion. Since ancient astronomers noted that occasionally a planet would exhibit retrograde motion--would seem to reverse its direction and move briefly westward--they concluded that the planets moved in epicyclic curves, circles with smaller interior loops, similar to the patterns of a child's Spirograph. With the coming of the Copernican revolution, the retrograde motion was seen to be apparent rather than real, leading to the idea that the planets moved in ellipses. This laid the ground for Newton's great achievement--integrating the concepts of astronomy and mechanics--which revealed not only how the planets moved, but also why. Throughout, Benson focuses on naked-eye astronomy, which makes it easy for the novice to grasp the work of these pioneers of astronomy.

Life s Ratchet How Molecular Machines Extract Order from Chaos

Life s Ratchet  How Molecular Machines Extract Order from Chaos Author Hoffmann, Peter M.
Release 2012-10-29
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Life s Ratchet How Molecular Machines Extract Order from Chaos has been writing in one form or another for most of life. You can find so many inspiration from Life s Ratchet How Molecular Machines Extract Order from Chaos also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Life s Ratchet How Molecular Machines Extract Order from Chaos book for free.

The Machinery of Life

The Machinery of Life Author David S. Goodsell
ISBN-10 9781475722673
Release 2013-03-09
Pages 140
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A journey into the sub-microscopic world of molecular machines. Readers are first introduced to the types of molecules built by cells: proteins, nucleic acids, lipids, and polysaccharides. Then, in a series of distinctive illustrations, the reader is guided through the interior world of cells, exploring the ways in which molecules work in concert to perform the processes of living. Finally, the author shows us how vitamins, viruses, poisons, and drugs each have their effects on the molecules in our bodies. David Goodsell, author and illustrator, has prepared a fascinating introduction to biochemistry for the non-specialist. His book combines a lucid text with an abundance of drawings and computer graphics that present the world of cells and their components in a truly unique way.

The Deeper Genome

The Deeper Genome Author John Parrington
ISBN-10 9780198813095
Release 2017-08-24
Pages 400
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Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought -- just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportion of DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'? Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact of its 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes of Neanderthals as well as that of chimps about the development of our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.


Complexity Author Mitchell M. Waldrop
ISBN-10 9780671872342
Release 1993-09-01
Pages 380
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A look at the rebellious thinkers who are challenging old ideas with their insights into the ways countless elements of complex systems interact to produce spontaneous order out of confusion