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Life s Ratchet

Life s Ratchet Author Peter M. Hoffmann
ISBN-10 9780465022533
Release 2012
Pages 278
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A physicist describes how life emerges from the random motion of atoms through sophisticated cellular machinery and describes the long quest to determine the true nature of life from ancient Greece to the study of modern nanotechnology. 20,000 first printing.

Brave Genius

Brave Genius Author Sean B. Carroll
ISBN-10 9780307952356
Release 2013-09-24
Pages 576
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The never-before-told account of the intersection of some of the most insightful minds of the 20th century, and a fascinating look at how war, resistance, and friendship can catalyze genius. In the spring of 1940, the aspiring but unknown writer Albert Camus and budding scientist Jacques Monod were quietly pursuing ordinary, separate lives in Paris. After the German invasion and occupation of France, both men joined the Resistance to help liberate the country from the Nazis, ascended to prominent, dangerous roles, and were very lucky to survive. After the war and through twists of circumstance, they became friends, and through their passionate determination and rare talent they emerged as leading voices of modern literature and biology, each receiving the Nobel Prize in his respective field. Drawing upon a wealth of previously unpublished and unknown material gathered over several years of research, Brave Genius tells the story of how Camus and Monod endured the most terrible episode of the twentieth century and then blossomed into remarkably creative and engaged individuals. It is a story of the transformation of ordinary lives into exceptional lives by extraordinary events—of courage in the face of overwhelming adversity, the flowering of creative genius, deep friendship, and profound concern for and insight into the human condition.

Life s Ratchet How Molecular Machines Extract Order from Chaos

Life s Ratchet  How Molecular Machines Extract Order from Chaos Author Hoffmann, Peter M.
Release 2012-10-29
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Life s Ratchet How Molecular Machines Extract Order from Chaos has been writing in one form or another for most of life. You can find so many inspiration from Life s Ratchet How Molecular Machines Extract Order from Chaos also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Life s Ratchet How Molecular Machines Extract Order from Chaos book for free.

Molecular Machines

Molecular Machines Author Benoît Roux
ISBN-10 9789814343466
Release 2011
Pages 288
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Molecular machines are complex biomolecules, proteins, nucleic acids, and carbohydrates that consume energy in order to perform specific functions. The concerted action of all those machines underlies all the activities of the living cell. To understand how such molecular machines are able to perform their function, it is necessary to identify the different moving parts and understand how they act together. Breaking new ground with these difficult problems is likely to require novel paradigms permitting a seamless integration of structural, dynamical and functional data from experiments and theory. The goal of this volume is to provide an introduction to the world of biological molecular machines to a broad audience of students and researchers in biosciences. Each chapter is written by leading experts to cover results from cutting-edge research, while remaining broadly accessible. The volume presents the current state of knowledge for several important systems, ranging from polymerases, the ribosome, chaperonins, the chromatophore, kinases, actin and myosin, membrane transporters, and voltage-gated ion channels, thus giving students and researches in biosciences a pedagogically integrated picture of this exciting and rapidly expanding field.

Into the Cool

Into the Cool Author Eric D. Schneider
ISBN-10 9780226739366
Release 2005-06-01
Pages 362
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Demonstrates how the second law of thermodynamics--which refers to energy's tendency to change from being concentrated in one place to being spread out over time--is behind evolution, ecology, economics, and even the origins of life itself in this scientific tour de force that explores how complex systems emerge, enlarge, and reproduce in a chaotic world.

What Is Life

What Is Life Author Addy Pross
ISBN-10 9780198784791
Release 2016-03-29
Pages 224
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Seventy years ago, Erwin Schrodinger posed a profound question: 'What is life, and how did it emerge from non-life?' This problem has puzzled biologists and physical scientists ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of 'systems chemistry' are unlocking the problem. Addy Pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life. Strikingly, he demonstrates that Darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle. The gulf between biology and the physical sciences is finally becoming bridged. This new edition includes an Epilogue describing developments in the concepts of fundamental forms of stability discussed in the book, and their profound implications. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.

Life from an RNA World

Life from an RNA World Author Michael Yarus
ISBN-10 0674050754
Release 2010
Pages 198
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A majority of evolutionary biologists believe that we now can envision our biological predecessorsâe"not the first, but nearly the first, living beings on Earth. Life from an RNA World is about these vanished forebears, sketching them in the distant past just as their workings first began to resemble our own. The advances that have made such a pursuit possible are rarely discussed outside of bio-labs. So here, says author Michael Yarus, is an album for interested non-biologists, an introduction to our relatives in deep time, slouching between the first rudimentary life on Earth and the appearance of more complex beings. The era between, and the focus of Yarusâe(tm) work, is called the RNA world. It is RNA (ribonucleic acid) long believed to be a mere biologic copier and messenger, that offers us this glimpse into our ancient predecessors. To describe early RNA creatures, here called âeoeribocytesâe or RNA cells, Yarus deploys some basics of molecular biology. He reviews our current understanding of the tree of life, examines the structure of RNA itself, explains the operation of the genetic code, and covers much elseâe"all in an effort to reveal a departed biological world across billions of years between its heyday and ours. Courting controversy among those who question the role of âeoeribocytesâe âe"citing the chemical fragility of RNA and the uncertainty about the origin of an RNA synthetic apparatusâe"Yarus offers an invaluable vision of early life on Earth. And his book makes that early form of life, our ancestor within, accessible to all of us.

Nature s Robots

Nature s Robots Author Charles Tanford
ISBN-10 9780191578519
Release 2003-11-27
Pages 312
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Proteins are amazingly versatile molecules. They make the chemical reactions happen that form the basis for life, they transmit signals in the body, they identify and kill foreign invaders, they form the engines that make us move, and they record visual images. All of this is now common knowledge, but it was not so a hundred years ago. Nature's Robots is an authoritative history of protein science, from the origins of protein research in the nineteenth century, when the chemical constitution of 'protein' was first studied and heatedly debated and when there was as yet no glimmer of the functional potential of substances in the 'protein' category, to the determination of the first structures of individual proteins at atomic resolution - when positions of individual atoms were first specified exactly and bonding between neighbouring atoms precisely defined. Tanford and Reynolds, who themselves made major contributions to the golden age of protein science, have written a remarkably vivid account of this history. It is a fascinating story, involving heroes from the past, working mostly alone or in small groups, usually with little support from formal research groups. It is also a story that embraces a number of historically important scientific controversies. Written in clear and accessible prose, Nature's Robots will appeal to general readers with an interest in popular science, in addition to professional scientists and historians of science.


Wetware Author Dennis Bray
ISBN-10 9780300155440
Release 2009
Pages 267
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Wetware has been writing in one form or another for most of life. You can find so many inspiration from Wetware also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Wetware book for free.

Molecular Machines in Biology

Molecular Machines in Biology Author Joachim Frank
ISBN-10 9781139499903
Release 2011-12-19
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The concept of molecular machines in biology has transformed the medical field in a profound way. Many essential processes that occur in the cell, including transcription, translation, protein folding and protein degradation, are all carried out by molecular machines. This volume focuses on important molecular machines whose architecture is known and whose functional principles have been established by tools of biophysical imaging (X-ray crystallography and cryo-electron microscopy) and fluorescence probing (single-molecule FRET). This edited volume includes contributions from prominent scientists and researchers who understand and have explored the structure and functions of these machines. This book is essential for students and professionals in the medical field who want to learn more about molecular machines.

Molecular Biology of Assemblies and Machines

Molecular Biology of Assemblies and Machines Author Alasdair C. Steven
ISBN-10 9781134982820
Release 2016-02-18
Pages 888
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Molecular Biology of Assemblies and Machines presents a comprehensive narrative describing the structures of macromolecular complexes and how they assemble and interact. Richly illustrated, it is written for advanced undergraduates, graduate students, and researchers in biochemistry, structural biology, molecular biology, biophysics, cell biology, and microbiology, and will also appeal to those in chemistry, immunology, and medicine. Essentially all major biological activities are performed by assemblies of macromolecules (proteins, RNA, and DNA) acting in concert. These assemblies are dynamic and many are endowed with machine-like properties. This unique book explores the molecular mechanisms employed at the critical level between individual macromolecules and cells and organelles.

The Machinery of Life

The Machinery of Life Author David S. Goodsell
ISBN-10 9781475722673
Release 2013-03-09
Pages 140
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A journey into the sub-microscopic world of molecular machines. Readers are first introduced to the types of molecules built by cells: proteins, nucleic acids, lipids, and polysaccharides. Then, in a series of distinctive illustrations, the reader is guided through the interior world of cells, exploring the ways in which molecules work in concert to perform the processes of living. Finally, the author shows us how vitamins, viruses, poisons, and drugs each have their effects on the molecules in our bodies. David Goodsell, author and illustrator, has prepared a fascinating introduction to biochemistry for the non-specialist. His book combines a lucid text with an abundance of drawings and computer graphics that present the world of cells and their components in a truly unique way.

The Music of Life

The Music of Life Author Denis Noble
ISBN-10 0191578800
Release 2008-02-14
Pages 176
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What is Life? Decades of research have resulted in the full mapping of the human genome - three billion pairs of code whose functions are only now being understood. The gene's eye view of life, advocated by evolutionary biology, sees living bodies as mere vehicles for the replication of the genetic codes. But for a physiologist, working with the living organism, the view is a very different one. Denis Noble is a world renowned physiologist, and sets out an alternative view to the question - one that becomes deeply significant in terms of the living, breathing organism. The genome is not life itself. Noble argues that far from genes building organisms, they should be seen as prisoners of the organism. The view of life presented in this little, modern, post-genome project reflection on the nature of life, is that of the systems biologist: to understand what life is, we must view it at a variety of different levels, all interacting with each other in a complex web. It is that emergent web, full of feedback between levels, from the gene to the wider environment, that is life. It is a kind of music. Including stories from Noble's own research experience, his work on the heartbeat, musical metaphors, and elements of linguistics and Chinese culture, this very personal and at times deeply lyrical book sets out the systems biology view of life.

Atomic Evidence

Atomic Evidence Author David S. Goodsell
ISBN-10 9783319325101
Release 2016-08-04
Pages 182
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This book will take an evidence-based approach to current knowledge about biomolecules and their place in our lives, inviting readers to explore how we know what we know, and how current gaps in knowledge may influence the way we approach the information. Biomolecular science is increasingly important in our everyday life, influencing the choices we make about our diet, our health, and our wellness. Often, however, information about biomolecular science is presented as a list of immutable facts, discouraging critical thought. The book will introduce the basic tools of structural biology, supply real-life examples, and encourage critical thought about aspects of biology that are still not fully understood.

Vital Dust

Vital Dust Author Christian De Duve
ISBN-10 0465090451
Release 1995-12-22
Pages 384
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Is the emergence of life on Earth the result of a single chance event or combination of lucky accidents, or is it the outcome of biochemical forces woven into the fabric of the universe? And if inevitable, what are these forces, and how do they account not only for the origin of life but also for its evolution toward increasing complexity? Vital Dust is a groundbreaking history of life on Earth, a history that only someone of Chrisitian de Duve's stature and erudition could have written.

Life Unfolding

Life Unfolding Author Jamie A. Davies
ISBN-10 9780199673537
Release 2014-02
Pages 299
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Tells the story of human development from egg to adult, showing how the understanding of how human beings come to be has been transformed in recent years.

Cell Biology by the Numbers

Cell Biology by the Numbers Author Ron Milo
ISBN-10 9781317230694
Release 2015-12-01
Pages 400
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Very little in our human experience is truly comparable to the immensely crowded and bustling interior of a cell. Biological numeracy provides a new kind of understanding of the cellular world. This book brings together up-to-date quantitative data from the vast biological literature and uses the powerful tool of "back of the envelope" estimates to reveal fresh perspectives and insights from numbers commonly encountered in cell biology. Readers gain a feeling for the sizes, concentrations, energies, and rates that characterize the lives of cellsÑ thereby shedding new light on the microscopic realm.