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Microfluidic Devices in Nanotechnology

Microfluidic Devices in Nanotechnology Author Challa S. S. R. Kumar
ISBN-10 111802933X
Release 2010-11-29
Pages 407
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Explores the latest applications arising from the intersection of nanotechnology and microfluidics In the past two decades, microfluidics research has seen phenomenal growth, with many new and emerging applications in fields ranging from chemistry, physics, and biology to engineering. With the emergence of nanotechnology, microfluidics is currently undergoing dramatic changes, embracing the rising field of nanofluidics. This volume reviews the latest devices and applications stemming from the merging of nanotechnology with microfludics in such areas as drug discovery, bio-sensing, catalysis, electrophoresis, enzymatic reactions, and nanomaterial synthesis. Each of the ten chapters is written by a leading pioneer at the intersection of nanotechnology and microfluidics. Readers not only learn about new applications, but also discover which futuristic devices and applications are likely to be developed. Topics explored in this volume include: New lab-on-a-chip systems for drug delivery Integration of microfluidics with nanoneuroscience to study the nervous system at the single-cell level Recent applications of nanoparticles within microfluidic channels for electrochemical and optical affinity biosensing Novel microfluidic approaches for the synthesis of nanomaterials Next-generation alternative energy portable power devices References in each chapter guide readers to the primary literature for further investigation of individual topics. Overall, scientists, researchers, engineers, and students will not only gain a new perspective on what has been done, but also the nanotechnology tools they need to develop the next generation of microfluidic devices and applications. Microfluidic Devices for Nanotechnology is a two-volume publication, the first ever to explore the synergies between microfluidics and nanotechnology. The first volume covers fundamental concepts; this second volume examines applications.



Microfluidics for Medical Applications

Microfluidics for Medical Applications Author Albert van den Berg
ISBN-10 9781849737593
Release 2014-11-19
Pages 328
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Lab-on-a-chip devices for point of care diagnostics have been present in clinics for several years now. Alongside their continual development, research is underway to bring the organs and tissue on-a-chip to the patient, amongst other medical applications of microfluidics. This book provides the reader with a comprehensive review of the latest developments in the application of microfluidics to medicine and is divided into three main sections. The first part of the book discusses the state-of-the-art in organs and tissue on a chip; the second provides a thorough background to microfluidics for medicine, and the third (and largest) section provides numerous examples of point-of-care diagnostics. Written with students and practitioners in mind, and with contributions from the leaders in the field across the globe, this book provides a complete digest of the state-of-the-art in microfluidics medical devices and will provide a handy resource for any laboratory or clinic involved in the development or application of such devices.



Microfluidic Devices for Biomedical Applications

Microfluidic Devices for Biomedical Applications Author Xiujun James Li
ISBN-10 9780857097040
Release 2013-10-31
Pages 676
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Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications. The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores in detail a wide range of medical applications Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies Considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering



Microfluidic Devices in Nanotechnology

Microfluidic Devices in Nanotechnology Author Challa S. S. R. Kumar
ISBN-10 1118029224
Release 2010-11-29
Pages 350
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Nanotechnology, especially microfabrication, has been affecting every facet of traditional scientific disciplines. The first book on the application of microfluidic reactors in nanotechnology, Microfluidic Devices in Nanotechnology provides the fundamental aspects and potential applications of microfluidic devices, the physics of microfluids, specific methods of chemical synthesis of nanomaterials, and more. As the first book to discuss the unique properties and capabilities of these nanomaterials in the miniaturization of devices, this text serves as a one-stop resource for nanoscientists interested in microdevices.



Microfabrication for Industrial Applications

Microfabrication for Industrial Applications Author Regina Luttge
ISBN-10 9780815519775
Release 2011-08-31
Pages 312
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This book focuses on the industrial perspective for micro- and nanofabrication methods including large-scale manufacturing, transfer of concepts from lab to factory, process tolerance, yield, robustness, and cost. It gives a history of miniaturization, micro- and nanofabrication, and surveys industrial fields of application, illustrating fabrication processes of relevant micro and nano devices. Concerning sub-micron feature manufacture, the book explains: the philosophy of micro/ nanofabrication for integrated circuit industry; thin film deposition; (waveguide, plastic, semiconductor) material processing; packaging; interconnects; stress (e.g., thin film residual); economic; and environmental aspects. Micro/nanomechanical sensors and actuators are explained in depth with information on applications, materials (incl. functional polymers), methods, testing, fabrication, integration, reliability, magnetic microstructures, etc. Shows engineers & students how to evaluate the potential value of current and nearfuture manufacturing processes for miniaturized systems in industrial environments Explains the top-down and bottom up approaches to nanotechnology, nanostructures fabricated with beams, nano imprinting methods, nanoparticle manufacturing (and their health aspects), nanofeature analysis, and connecting nano to micro to macro Discusses issues for practical application cases; possibilities of dimension precision; large volume manufacturing of micro- & nanostructures (machines, materials, costs) Explains applications of Microsystems for information technology, e.g.: data recording (camera, microphone), storage (memories, CDs), communication; computing; and displays (beamers, LCD, TFT) Case studies are given for sensors, resonators, probes, transdermal medical systems, micro- pumps & valves, inkjets, DNA-analysis, lab-on-a-chip, & micro-cooling



Biosensors and Nanotechnology

Biosensors and Nanotechnology Author Zeynep Altintas
ISBN-10 9781119065012
Release 2017-12-18
Pages 400
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General introduction to biosensors and recognition receptors -- Biomarkers in health care -- The use of nanomaterials and microfluidics in medical diagnostics -- SPR-based biosensor technologies in disease detection and diagnostics -- Piezoelectric-based biosensor technologies in disease detection and diagnostics -- Electrochemical-based biosensor technologies in disease detection and diagnostics -- MEMS-based cell counting methods -- Lab-on-a-chip platforms for disease detection and diagnosis -- Applications of quantum dots in biosensors and diagnostics -- Applications of molecularly imprinted nanostructures in biosensors and diagnostics -- Smart nanomaterial's : applications in biosensors and diagnostics -- Applications of magnetic nanomaterial's in biosensors and diagnostics -- Graphene applications in biosensors and diagnostics -- Optical biosensors and applications to drug discovery for cancer cases -- Biosensors for detection of anticancer drug-DNA interactions



Microfluidics

Microfluidics Author Yujun Song
ISBN-10 9783527800650
Release 2018-01-04
Pages 352
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The first book offering a global overview of fundamental microfluidics and the wide range of possible applications, for example, in chemistry, biology, and biomedical science. As such, it summarizes recent progress in microfluidics, including its origin and development, the theoretical fundamentals, and fabrication techniques for microfluidic devices. The book also comprehensively covers the fluid mechanics, physics and chemistry as well as applications in such different fields as detection and synthesis of inorganic and organic materials. A useful reference for non-specialists and a basic guideline for research scientists and technicians already active in this field or intending to work in microfluidics.



Microfluidics in Detection Science

Microfluidics in Detection Science Author Fatima H Labeed
ISBN-10 9781849737609
Release 2014-10-24
Pages 281
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The concept of a miniaturised laboratory on a disposable chip is now a reality, and in everyday use in industry, medicine and defence. New devices are launched all the time, prompting the need for a straightforward guide to the design and manufacture of lab-on-a-chip (LOC) devices. This book presents a modular approach to the construction and integration of LOC components in detection science. The editors have brought together some of the leading experts from academia and industry to present an accessible guide to the technology available and its potential. Several chapters are devoted to applications, presenting both the sampling regime and detection methods needed. Further chapters describe the integration of LOC devices, not only with each other but also into existing technologies. With insights into LOC applications, from biosensing to molecular and chemical analysis, and presenting scaled-down versions of existing technology alongside unique approaches that exploit the physics of the micro and nano-scale, this book will appeal to newcomers to the field and practitioners requiring a convenient reference.



Microfluidics for Pharmaceutical Applications

Microfluidics for Pharmaceutical Applications Author Helder a Santos
ISBN-10 0128126590
Release 2018-09-15
Pages 560
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Microfluidics for Pharmaceutical Applications: From Nano/Micro Systems Fabrication to Controlled Drug Delivery is a concept-orientated reference that features case studies on utilizing microfluidics for drug delivery applications. It is a valuable learning reference on microfluidics for drug delivery applications and assists practitioners developing novel drug delivery platforms using microfluidics. It explores advances in microfluidics for drug delivery applications from different perspectives, covering device fabrication, fluid dynamics, cutting-edge microfluidic technology in the global drug delivery industry, lab-on-chip nano/micro fabrication and drug encapsulation, cell encapsulation and delivery, and cell- drug interaction screening. These microfluidic platforms have revolutionized the drug delivery field, but also show great potential for industrial applications. Presents detailed coverage on the fabrication of novel drug delivery systems with desired characteristics, such as uniform size, Janus particles, and particular or combined responsiveness Includes a variety of case studies that explain principles Focuses on commercialization, cost, safety, society and educational issues of microfluidic applications, showing how microfluidics is used in the real world



Nanofluidics and Microfluidics

Nanofluidics and Microfluidics Author Shaurya Prakash
ISBN-10 9781437744705
Release 2014-01-16
Pages 312
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To provide an interdisciplinary readership with the necessary toolkit to work with micro- and nanofluidics, this book provides basic theory, fundamentals of microfabrication, advanced fabrication methods, device characterization methods and detailed examples of applications of nanofluidics devices and systems. Case studies describing fabrication of complex micro- and nanoscale systems help the reader gain a practical understanding of developing and fabricating such systems. The resulting work covers the fundamentals, processes and applied challenges of functional engineered nanofluidic systems for a variety of different applications, including discussions of lab-on-chip, bio-related applications and emerging technologies for energy and environmental engineering. The fundamentals of micro- and nanofluidic systems and micro- and nanofabrication techniques provide readers from a variety of academic backgrounds with the understanding required to develop new systems and applications. Case studies introduce and illustrate state-of-the-art applications across areas, including lab-on-chip, energy and bio-based applications. Prakash and Yeom provide readers with an essential toolkit to take micro- and nanofluidic applications out of the research lab and into commercial and laboratory applications.



Microfluidic Cell Culture Systems

Microfluidic Cell Culture Systems Author Christopher Bettinger
ISBN-10 9781437734607
Release 2012-12-31
Pages 452
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The fields of microfluidics and BioMEMS are significantly impacting cell biology research and applications through the application of engineering solutions to human disease and health problems. The dimensions of microfluidic channels are well suited to the physical scale of biological cells, and the many advantages of microfluidics make it an attractive platform for new techniques in biology. This new professional reference applies the techniques of microsystems to cell culture applications. The authors provide a thoroughly practical guide to the principles of microfluidic device design and operation and their application to cell culture techniques. The resulting book is crammed with strategies and techniques that can be immediately deployed in the lab. Equally, the insights into cell culture applications will provide those involved in traditional microfluidics and BioMEMS with an understanding of the specific demands and opportunities presented by biological applications. The goal is to guide new and interested researchers and technology developers to the important areas and state-of-the-practice strategies that will enhance the efficiency and value of their technologies, devices and biomedical products. Provides insights into the design and development of microfluidic systems with a specific focus on cell culture applications Focuses on strategies and techniques for the design and fabrication of microfluidic systems and devices for cell culture Provides balanced coverage of microsystems engineering and bioengineering



Fundamentals and Applications of Microfluidics

Fundamentals and Applications of Microfluidics Author Nam-Trung Nguyen
ISBN-10 1580533434
Release 2002-01
Pages 471
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Annotation This introduction to the emerging field of microfluidics explains how to take advantage of the performance benefits of microfluidics and serves as a reference for technology and applications in this area. It offers practical guidance on how to model, design, and fabricate microfluidic devices, and discusses a range of microfluidic applications, including fluid control devices, gas and fluid measurement devices, medical testing equipment, and implantable drug pumps. Calculations, data tables, and rules of thumb are provided to help practitioners make design decisions and determine device characteristics. Nguyen is an assistant professor at the School of Mechanical and Production Engineering at Nanyang Technological University, Singapore. Wereley is an assistant professor of mechanical engineering at Purdue University. Annotation copyrighted by Book News, Inc., Portland, OR



Springer Handbook of Nanotechnology

Springer Handbook of Nanotechnology Author Bharat Bhushan
ISBN-10 9783662543573
Release 2017-11-05
Pages 1500
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This comprehensive handbook has become the definitive reference work in the field of nanoscience and nanotechnology, and this 4th edition incorporates a number of recent new developments. It integrates nanofabrication, nanomaterials, nanodevices, nanomechanics, nanotribology, materials science, and reliability engineering knowledge in just one volume. Furthermore, it discusses various nanostructures; micro/nanofabrication; micro/nanodevices and biomicro/nanodevices, as well as scanning probe microscopy; nanotribology and nanomechanics; molecularly thick films; industrial applications and nanodevice reliability; societal, environmental, health and safety issues; and nanotechnology education. In this new edition, written by an international team of over 140 distinguished experts and put together by an experienced editor with a comprehensive understanding of the field, almost all the chapters are either new or substantially revised and expanded, with new topics of interest added. It is an essential resource for anyone working in the rapidly evolving field of key technology, including mechanical and electrical engineers, materials scientists, physicists, and chemists.



Microfluidic Devices in Nanotechnology Handbook

Microfluidic Devices in Nanotechnology Handbook Author Challa S. S. R. Kumar
ISBN-10 0470876115
Release 2010-08-02
Pages 1000
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This two-volume set covers fundamental concepts and applications highlighting the synergy between microfluidics and nanotechnology. Volume 1 provides readers with up-to-date knowledge about fluid and particle kinetics, spatiotemporal control, fluid dynamics, residence time distribution and nanoparticle focusing within microfluidics. Volume 2 discusses its applications in fields ranging from chemistry, biology, molecular and cell biology, neuroscience, catalysis and nanomaterials synthesis. For nanomaterials chemists, this book provides an excellent source of information covering a wide variety of microfluidic-based approaches for synthesis of metallic as well as non metallic nanomaterials.



Nanomaterials for Biosensors

Nanomaterials for Biosensors Author Bansi D. Malhotra
ISBN-10 9780128135150
Release 2017-10-26
Pages 332
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Nanomaterials for Biosensors: Fundamentals and Applications provides a detailed summary of the main nanomaterials used in biosensing and their application. It covers recent developments in nanomaterials for the fabrication of biosensor devices for healthcare diagnostics, food freshness and bioprocessing. The various processes used for synthesis and characterization of nanostructured materials are examined, along with the design and fabrication of bioelectronic devices using nanostructured materials as building blocks. Users will find the fundamentals of the main nanomaterials used in biosensing, helping them visualize a systematic and coherent picture of how nanomaterials are used in biosensors. The book also addresses the role of bio-conjugation of nanomaterials in the construction of nano-biointerfaces for application in biosensors. Such applications, including metal nanoparticles, metal oxide nanoparticles, nanocomposites, carbon nanotubes, conducting polymers and plasmonic nanostructures in biosensing are discussed relative to each nanomaterial concerned. Finally, recent advancements in protein functionalized nanomaterials for cancer diagnostics and bio-imaging are also included. Provides a detailed study on how nanomaterials are used to enhance sensing capabilities in biosensors Explains the properties, characterization methods and preparation techniques of the nanomaterials used in biosensing Arranged in a material-by-material way, making it clear how each nanomaterial should be used



Molecular Sensors and Nanodevices

Molecular Sensors and Nanodevices Author John X J Zhang
ISBN-10 9781455776764
Release 2013-12-03
Pages 512
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With applications ranging from medical diagnostics to environmental monitoring, molecular sensors (also known as biosensors, chemical sensors, or chemosensors), along with emerging nanotechnologies offer not only valuable tools but also unlimited possibilities for engineers and scientists to explore the world. New generation of functional microsystems can be designed to provide a variety of small scale sensing, imaging and manipulation techniques to the fundamental building blocks of materials. This book provides comprehensive coverage of the current and emerging technologies of molecular sensing, explaining the principles of molecular sensor design and assessing the sensor types currently available. Having explained the basic sensor structures and sensing principles, the authors proceed to explain the role of nano/micro fabrication techniques in molecular sensors, including MEMS, BioMEMS, MicroTAS among others. The miniaturization of versatile molecular sensors opens up a new design paradigm and a range of novel biotechnologies, which is illustrated through case studies of groundbreaking applications in the life sciences and elsewhere. As well as the techniques and devices themselves, the authors also cover the critical issues of implantability, biocompatibility and the regulatory framework. The book is aimed at a broad audience of engineering professionals, life scientists and students working in the multidisciplinary area of biomedical engineering. It explains essential principles of electrical, chemical, optical and mechanical engineering as well as biomedical science, intended for readers with a variety of scientific backgrounds. In addition, it will be valuable for medical professionals and researchers. An online tutorial developed by the authors provides learning reinforcement for students and professionals alike. Reviews of state-of-the-art molecular sensors and nanotechnologies Explains principles of sensors and fundamental theories with homework problems at the end of each chapter to facilitate learning Demystifies the vertical integration from nanomaterials to devices design Covers practical applications the recent progress in state-of-the-art sensor technologies Includes case studies of important commercial products Covers the critical issues of implantability, biocompatibility and the regulatory framework



Microfluidics Nanotechnology and Disease Biomarkers for Personalized Medicine Applications

Microfluidics  Nanotechnology and Disease Biomarkers for Personalized Medicine Applications Author Muhammad J. A. Shiddiky
ISBN-10 1628080205
Release 2013-01-01
Pages 227
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In recent years, thousands of cancer biomarkers have been discovered and described in scientific literature. The promise of personalized medicine, where diseases such as cancer are accurately diagnosed and treatments tailored specifically for individuals, is becoming a reality. Significant advances in biomarker-based research methodologies such as Next Generation Sequencing (NGS) are at the cusp of ushering in a new era of personal medicine. However, unlike the spectacular advances in research technologies for disease biomarker discovery, biomarker-based technologies that can effectively be used in the clinic (or point-of-care) to enable personalized medicine are still lacking. In this book, we feature a selection of emerging technologies which are aimed at enabling clinical applications of personalised medicine. Each of the eight chapters is written by a leading group at the intersection of microfluidics, biology, and nanotechnology. For instance, to accelerate a major bottleneck in the development of clinically useful protein diagnostics, we discuss the application of yeast-derived single chain Fragment variable (scFv) antibody-like molecules as a potential low cost alternative to traditional antibody-based diagnostics. Circulating tumour cells (CTCs) are an emerging class of cancer biomarkers and a potential resource for understanding cancer progression; we explore various strategies combining microfluidics with nanotechnology for capturing CTCs. The book includes an evaluation of some current and emerging technologies for detecting clinical DNA methylation, another potential cancer biomarker. As personalized medicine may involve tracking a patient's response to treatment, the application of microfluidics to detect metabolites in biological fluids is also discussed. Finally, the ultimate goal of personalized medicine is targeted therapy. One promising approach is RNAi technology which uses short nucleotides to disrupt cancer pathways. In this book, nanoparticle approaches to deliver these short nucleotides are discussed