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Neurobiology of Psychiatric Disorders

Neurobiology of Psychiatric Disorders Author Thomas E. Schlaepfer
ISBN-10 9780444520029
Release 2012
Pages 760
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This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders A "must have" reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain



Neurobiology of Brain Disorders

Neurobiology of Brain Disorders Author Michael J. Zigmond
ISBN-10 9780123982803
Release 2014-12-03
Pages 824
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Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material



Neuroscience for the Mental Health Clinician Second Edition

Neuroscience for the Mental Health Clinician  Second Edition Author Steven R. Pliszka
ISBN-10 9781462527120
Release 2016-08-21
Pages 324
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Accessible and succinct, this book has given thousands of clinicians and students the basic understanding of neuroscience that is essential in contemporary mental health practice. Steven R. Pliszka synthesizes current knowledge on the neurobiological bases of major psychiatric disorders. He explores the brain systems that underlie cognition, emotions, and behavior; how disturbances in these systems can lead to psychopathology; and the impact of genetic and environmental risk factors across development. The book also addresses the ways that both pharmacological and psychosocial treatments act on the brain as they bring about a reduction in symptoms. Illustrations include 93 black-and-white figures and 14 color plates. New to This Edition *Incorporates over a decade of important advances in brain science. *Heightened focus on brain networks. *Cutting-edge discussions of genetics and epigenetics, the biological impact of stress, neurotransmitters, novel depression treatments, and other timely topics. *Detailed chapters on autism spectrum disorder and dementia. *Numerous new and revised figures.



Psychiatry and Clinical Neuroscience

Psychiatry and Clinical Neuroscience Author Charles Zorumski
ISBN-10 9780199768769
Release 2011-06-16
Pages 300
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Psychiatric disorders are brain disorders, reflecting dysfunction within and across neural networks. Advances in functional neuroimaging and cellular neuroscience offer hope of revolutionizing the approach to diagnosis and treatment of mental illnesses. This book presents an introduction to network neuroscience and demonstrates the relationship of advances in this field to the future of psychiatry.



Clinical Neuroscience

Clinical Neuroscience Author Kelly Lambert
ISBN-10 0716752271
Release 2004-11-26
Pages 531
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The first and only textbook of its kind, Clinical Neuroscience integrates neurobiological mechanisms of general health into the coverage of mental disorders. With this resource, instructors can easily integrate principles of neuroscience into clinical, developmental, behavioral, cognitive, and social psychology.



Literature Neurology and Neuroscience Neurological and Psychiatric Disorders

Literature  Neurology  and Neuroscience  Neurological and Psychiatric Disorders Author
ISBN-10 9780444633873
Release 2013-12-11
Pages 252
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This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume on the neurosciences, neurology, and literature vividly shows how science and the humanities can come together --- and have come together in the past. Its sections provide a new, broad look at these interactions, which have received surprisingly little attention in the past. Experts in the field cover literature as a window to neurological and scientific zeitgeists, theories of brain and mind in literature, famous authors and their suspected neurological disorders, and how neurological disorders and treatments have been described in literature. In addition, a myriad of other topics are covered, including some on famous authors whose important connections to the neurosciences have been overlooked (e.g., Roget, of Thesaurus fame), famous neuroscientists who should also be associated with literature, and some overlooked scientific and medical men who helped others produce great literary works (e,g., Bram Stoker's Dracula). There has not been a volume with this coverage in the past, and the connections it provides should prove fascinating to individuals in science, medicine, history, literature, and various other disciplines. This book looks at literature, medicine, and the brain sciences both historically and in the light of the newest scholarly discoveries and insights



Neurobiology of Mental Illness

Neurobiology of Mental Illness Author Dennis S. Charney
ISBN-10 9780199934959
Release 2013-07-04
Pages 1222
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Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.



Neuroscience of Clinical Psychiatry

Neuroscience of Clinical Psychiatry Author Edmund S. Higgins
ISBN-10 9781469830155
Release 2013-05-07
Pages 336
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Little information from this complex and evolving field of neuroscience has been readily accessible to the clinical psychiatrist on the front lines of patient care, let alone to the resident preparing for the Boards. There thus has existed a need for a concise and accessible text that builds a bridge between the two disciplines. To meet this need, the fully updated Second Edition of this straightforward and reader-friendly reference provides readers with a basic link between the science of the brain and the treatment of common mental health disorders. Both comprehensive and easy to follow, this textbook is being used in psychology graduate programs, nurse practitioner training and psychiatry residencies. It is useful for board exam review as well as for the practicing clinician looking to keep pace with the latest advances in neuroscience. The book’s clear and direct language will enhance your understanding of basic neuroscientific concepts underlying commonly encountered disorders, and the effects of brain chemistry on common behaviors. Practical applications, insightful illustrations, and review questions following each chapter help solidify your grasp of neuropathology and its link to mental health disorders and their treatment.



Neurogenetics

Neurogenetics Author
ISBN-10 9780444632357
Release 2018-01-08
Pages 436
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Genetic methodologies are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is evolving rapidly and expected to grow in scope as more disorders are linked to specific genetic markers. Part I covers basic genetic concepts and recurring biological themes, and begins the discussion of movement disorders and neurodevelopmental disorders, leading the way for Part II to cover a combination of neurological, neuromuscular, cerebrovascular, and psychiatric disorders. This volume in the Handbook of Clinical Neurology will provide a comprehensive introduction and reference on neurogenetics for the clinical practitioner and the research neurologist. Presents a comprehensive coverage of neurogenetics Details the latest science and impact on our understanding of neurological psychiatric disorders Provides a focused reference for clinical practitioners and the neuroscience/neurogenetics research community



Brain Banking

Brain Banking Author
ISBN-10 9780444636423
Release 2018-02-27
Pages 448
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Brain Banking, Volume 150, serves as the only book on the market offering comprehensive coverage of the functional realities of brain banking. It focuses on brain donor recruitment strategies, brain bank networks, ethical issues, brain dissection/tissue processing/tissue dissemination, neuropathological diagnosis, brain donor data, and techniques in brain tissue analysis. In accordance with massive initiatives, such as BRAIN and the EU Human Brain Project, abnormalities and potential therapeutic targets of neurological and psychiatric disorders need to be validated in human brain tissue, thus requiring substantial numbers of well characterized human brains of high tissue quality with neurological and psychiatric diseases. Offers comprehensive coverage of the functional realities of brain banking, with a focus on brain donor recruitment strategies, brain bank networks, ethical issues, and more Serves as a valuable resource for staff in existing brain banks by highlighting best practices Enhances the sharing of expertise between existing banks and highlights a range of techniques applicable to banked tissue for neuroscience researchers Authored by leaders from brain banks around the globe – the broadest, most expert coverage available



Translational Neuroscience

Translational Neuroscience Author James E. Barrett
ISBN-10 9781139510301
Release 2012-06-28
Pages
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Translational neuroscience is at the heart of clinical advancement in the fields of psychiatry, neurology and neurodevelopmental disorders. Written and edited by leading scientists and clinicians, this is a comprehensive and authoritative analysis of this emerging strategy for developing more effective treatments for brain disorders. Introductory chapters bring together perspectives from both academia and industry, while subsequent sections focus on disease groups, including bipolar disorder and depression, attention deficit hyperactivity disorder, substance abuse, autism, Alzheimer's disease, pain, epilepsy, Parkinson's disease and multiple sclerosis. Each section includes topical introductory and summary chapters, providing an overview and synthesis of the field. Translational Neuroscience: Applications in Psychiatry, Neurology, and Neurodevelopmental Disorders is an important text for clinicians, scientists and students in academic settings, government agencies and industry, as well as those working in the fields of public health and the behavioural sciences.



Computational Psychiatry

Computational Psychiatry Author Alan Anticevic
ISBN-10 9780128098264
Release 2017-09-19
Pages 332
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Computational Psychiatry: Mathematical Modeling of Mental Illness is the first systematic effort to bring together leading scholars in the fields of psychiatry and computational neuroscience who have conducted the most impactful research and scholarship in this area. It includes an introduction outlining the challenges and opportunities facing the field of psychiatry that is followed by a detailed treatment of computational methods used in the service of understanding neuropsychiatric symptoms, improving diagnosis and guiding treatments. This book provides a vital resource for the clinical neuroscience community with an in-depth treatment of various computational neuroscience approaches geared towards understanding psychiatric phenomena. Its most valuable feature is a comprehensive survey of work from leaders in this field. Offers an in-depth overview of the rapidly evolving field of computational psychiatry Written for academics, researchers, advanced students and clinicians in the fields of computational neuroscience, clinical neuroscience, psychiatry, clinical psychology, neurology and cognitive neuroscience Provides a comprehensive survey of work from leaders in this field and a presentation of a range of computational psychiatry methods and approaches geared towards a broad array of psychiatric problems



The Hippocampus in Clinical Neuroscience

The Hippocampus in Clinical Neuroscience Author K. Szabo
ISBN-10 9783318025682
Release 2014-04-23
Pages 172
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The hippocampus is one of the most intriguing structures of the human brain. Damage to this part causes symptoms ranging from transient disorders accompanied by tiny lesions to severely debilitating cognitive disorders with marked tissue loss. This publication provides a predominantly clinical approach to the complex workings of the hippocampus from different perspectives, ranging from basic principles to specific diseases. The first part of the book summarizes current knowledge regarding the structure and physiology of the hippocampus and establishes the ties to basic neuroscience. The second part deals with the function and assessment of the human hippocampus, including memory function, neuropsychological measures, and conventional and functional imaging studies. The chapters of the third part are devoted to the hippocampus in neurological disorders, e.g. the interaction between stress and memory function, and the pathological conditions of common as well as selected rare neurological diseases affecting the hippocampus. The book is highly recommended to clinical neurologists who wish to gain a broad understanding of this complex and fascinating organ in terms of basic principles, modern imaging findings, and specific diseases.



Alcohol and the Nervous System

Alcohol and the Nervous System Author Edith V. Sullivan
ISBN-10 9780444626226
Release 2014-10-08
Pages 704
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Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. The first focused reference specifically on alcohol and the brain Details our current understanding of how alcohol impacts the central nervous system Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse Includes section on neuroimaging of neurochemical markers and brain function



Functional Neurologic Disorders

Functional Neurologic Disorders Author
ISBN-10 9780128018491
Release 2016-10-06
Pages 680
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Functional Neurologic Disorders, the latest volume in the Handbook of Clinical Neurology series, summarizes state-of-the-art research findings and clinical practice on this class of disorders at the interface between neurology and psychiatry. This 51-chapter volume offers an historical introduction, chapters on epidemiology and pathophysiolology, a large section on the clinical features of different type of functional neurologic symptoms and disorders (including functional movement disorders, non-epileptic seizures, dizziness, vision, hearing, speech and cognitive symptoms), and then concluding with approaches to therapy. This group of internationally acclaimed experts in neurology, psychiatry, and neuroscience represent a broad spectrum of areas of expertise, chosen for their ability to write clearly and concisely with an eye toward a clinical audience. This HCN volume sets a new landmark standard for a comprehensive, multi-authored work dealing with functional neurologic disorders (also described as psychogenic, dissociative or conversion disorders). Offers a comprehensive interdisciplinary approach for the care of patients with functional disorders seen in neurologic practice, leading to more efficient prevention, management, and treatment Provides a synthesis of research efforts incorporating clinical, brain imaging and neurophysiological studies Fills an existing gap between traditional neurology and traditional psychiatry Contents include coverage of history, epidemiology, clinical presentations, and therapy Edited work with chapters authored by leaders in the field, the broadest, most expert coverage available



Music Neurology and Neuroscience Evolution the Musical Brain Medical Conditions and Therapies

Music  Neurology  and Neuroscience  Evolution  the Musical Brain  Medical Conditions  and Therapies Author
ISBN-10 9780444635525
Release 2015-03-02
Pages 292
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Did you ever ask whether music makes people smart, why a Parkinson patient's gait is improved with marching tunes, and whether Robert Schumann was suffering from schizophrenia or Alzheimer's disease? This broad but comprehensive book deals with history and new discoveries about music and the brain. It provides a multi-disciplinary overview on music processing, its effects on brain plasticity, and the healing power of music in neurological and psychiatric disorders. In this context, the disorders the plagued famous musicians and how they affected both performance and composition are critically discussed, and music as medicine, as well as music as a potential health hazard are examined. Among the other topics covered are: how music fit into early conceptions of localization of function in the brain, the cultural roots of music in evolution, and the important roles played by music in societies and educational systems. Topic: Music is interesting to almost everybody Orientation: This book looks at music and the brain both historically and in the light of the latest research findings Comprehensiveness: This is the largest and most comprehensive volume on "music and neurology" ever written! Quality of authors: This volume is written by a unique group of real world experts representing a variety of fields, ranging from history of science and medicine to neurology and musicology



Cerebrospinal Fluid in Neurologic Disorders

Cerebrospinal Fluid in Neurologic Disorders Author
ISBN-10 9780128043240
Release 2017-11-17
Pages 320
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Cerebrospinal Fluid in Neurologic Disorders, Volume 146 provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker. The second part addresses the main purpose of the volume, describing CSF from a research perspective in context with the most important diagnostic entities in neurology. The book's authors provide insight into the current understanding of CSF changes in these various conditions and what it tells us about the nature of neurological diseases. Furthermore, methodological aspects are discussed, as are shortcomings that need to be addressed. Finally, the book provides an outlook for potential directions that can be explored to improve the various aspects of CSF research with the ultimate goal of being incorporated in clinical practice. Provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker Addresses relevant research in context with the most important diagnostic entities in neurology Edited by leading authors in CSF research from around the globe, presenting the broadest, most expert coverage available