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Next Generation DNA Led Technologies

Next Generation DNA Led Technologies Author Sharada Avadhanam
ISBN-10 9789812876706
Release 2015-10-28
Pages 140
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This brief highlights advances in DNA technologies and their wider applications. DNA is the source of life and has been studied since a generation, but very little is known as yet. Several sophisticated technologies of the current era have laid their foundations on the principle of DNA based mechanisms. DNA based technologies are bringing a new revolution of Advanced Science and Technology. Forensic Investigation, Medical Diagnosis, Paternity Disputes, Individual Identity, Health insurance, Motor Insurance have incorporated the DNA testing and profiling technologies for settling the issues.



Next Generation Sequencing Technologies and Challenges in Sequence Assembly

Next Generation Sequencing Technologies and Challenges in Sequence Assembly Author Sara El-Metwally, M.Sc
ISBN-10 9781493907151
Release 2014-04-19
Pages 118
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The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field. This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges.



Next Generation Sequencing Technologies in Medical Genetics

Next Generation Sequencing Technologies in Medical Genetics Author C. Alexander Valencia
ISBN-10 9781461490326
Release 2013-10-16
Pages 94
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This book introduces readers to Next Generation Sequencing applications in medical genetics. The authors discuss the direct application of next-generation sequencing to medicine, specifically, laboratory medicine or molecular diagnostics. The first part of the book contains chapters on sanger sequencing, NGS technologies, targeted-amplification and capture, and exome sequencing. The second part of the book focuses on genetic disorders diagnoses by NGS, prenatal diagnosis, muscular dystrophies, mitochondrial disorders diagnosis, and challenges in molecular diagnosis. Recent developments and potential future trends in NGS sequencing applications are highlighted, as well.​



Materials that Change Color

Materials that Change Color Author Marinella Ferrara
ISBN-10 9783319002903
Release 2013-11-18
Pages 139
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This book presents a design-driven investigation into smart materials developed by chemists, physicists, materials and chemical engineers, and applied by designers to consumer products. Introducing a class of smart materials, that change colors, the book presents their characteristics, advantages, potentialities and difficulties of applications of this to help understanding what they are, how they work, how they are applied. The books also present a number of case studies: products, projects, concepts and experiments using smart materials, thus mapping out new design territories for these innovative materials. These case studies involve different fields of design, including product, interior, fashion and communication design. Within the context of rising sustainable and human-centered design agendas, the series will demonstrate the role and influence of these new materials and technologies on design, and discuss how they can implement and redefine our objects and spaces to encourage more resilient environments.



Ethics Dumping

Ethics Dumping Author Doris Schroeder
ISBN-10 9783319647319
Release 2017-12-04
Pages 134
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This book is published under a CC BY 4.0 license. This book provides original, up-to-date case studies of “ethics dumping” that were largely facilitated by loopholes in the ethics governance of low and middle-income countries. It is instructive even to experienced researchers since it provides a voice to vulnerable populations from the fore mentioned countries. Ensuring the ethical conduct of North-South collaborations in research is a process fraught with difficulties. The background conditions under which such collaborations take place include extreme differentials in available income and power, as well as a past history of colonialism, while differences in culture can add a new layer of complications. In this context, up-to-date case studies of unethical conduct are essential for research ethics training.



Understanding and Modeling F rster type Resonance Energy Transfer FRET

Understanding and Modeling F  rster type Resonance Energy Transfer  FRET Author Alexander Govorov
ISBN-10 9789812873781
Release 2016-08-11
Pages 54
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This Brief presents a historical overview of the Förster-type nonradiative energy transfer and a compilation of important progress in FRET research, starting from Förster until today, along with a summary of the current state-of-the-art. Here the objective is to provide the reader with a complete account of important milestones in FRET studies and FRET applications as well as a picture of the current status.



Biological Physical and Technical Basics of Cell Engineering

Biological  Physical and Technical Basics of Cell Engineering Author Gerhard M. Artmann
ISBN-10 9789811079047
Release 2018-04-11
Pages 481
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This book presents and discusses recent scientific progress on Cell and Stem Cell Engineering. It predominantly focuses on Biological, Physical and Technical Basics, and features new trends of research reaching far into the 21st century.



Nearly Zero Energy Buildings and Proliferation of Microorganisms

Nearly Zero Energy Buildings and Proliferation of Microorganisms Author Elisa Di Giuseppe
ISBN-10 9783319023564
Release 2013-10-22
Pages 94
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This book provides a concise review of the thermo-physical phenomena which regulate heat and moisture transportation in Nearly Zero Energy Buildings envelopes, and their relationship with the growth of biological organisms. It describes the main microorganisms proliferating on contemporary building elements and within buildings. It also states the consequences of biological growth on durability, aesthetics and human health; and provides the main methods for the analytical and experimental evaluation of proliferation. Finally, through the review of recent developments, remedial actions to counter the biological phenomenon are examined, and an outline is provided for future innovations in a field not yet widely investigated.



Bioinformatics of Non Small Cell Lung Cancer and the Ras Proto Oncogene

Bioinformatics of Non Small Cell Lung Cancer and the Ras Proto Oncogene Author Amita Kashyap
ISBN-10 9789814585088
Release 2014-09-08
Pages 72
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Cancer is initiated by activation of oncogenes or inactivation of tumor suppressor genes. Mutations in the K-ras proto-oncogene are responsible for 10–30% of adenocarcinomas. Clinical Findings point to a wide variety of other cancers contributing to lung cancer incidence. Such a scenario makes identification of lung cancer difficult and thus identifying its mechanisms can contribute to the society. Identifying unique conserved patterns common to contributing proto-oncogenes may further be a boon to Pharmacogenomics and pharmacoinformatics. This calls for ab initio/de novo drug discovery that in turn will require a comprehensive in silico approach of Sequence, Domain, Phylogenetic and Structural analysis of the receptors, ligand screening and optimization and detailed Docking studies. This brief involves extensive role of the RAS subfamily that includes a set of proteins, which cause an over expression of cancer-causing genes like M-ras and initiate tumour formation in lungs. SNP Studies and Structure based drug discovery will also be undertaken.



Transactions on Engineering Technologies

Transactions on Engineering Technologies Author Sio-Iong Ao
ISBN-10 9789811027178
Release 2017-03-19
Pages 590
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This proceedings volume contains selected revised and extended research articles written by researchers who participated in the World Congress on Engineering and Computer Science 2015, held in San Francisco, USA, 21-23 October 2015. Topics covered include engineering mathematics, electrical engineering, circuits, communications systems, computer science, chemical engineering, systems engineering, manufacturing engineering, and industrial applications. The book offers the reader an overview of the state of the art in engineering technologies, computer science, systems engineering and applications, and will serve as an excellent reference work for researchers and graduate students working in these fields.



Nanoparticles in Lung Cancer Therapy Recent Trends

Nanoparticles in Lung Cancer Therapy   Recent Trends Author Abhijit Bandyopadhyay
ISBN-10 9788132221753
Release 2014-11-14
Pages 65
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This brief provides an insight into the present scenario of the role of nanotechnology in the diagnosis and treatment of lung cancer at an early stage. Currently, lung cancer is the subject of major concern owing to the very high mortality rate throughout the world. Most of the conventional treatment methods such as surgery, chemotherapy, radiotherapy, etc., fail to prolong life of the patients. Incidents of recurrence are also very common in case of lung cancer. Researchers have shown that nanoparticles may act as a powerful anti cancer tool, especially for lung cancer. Unique surface properties and easy surface functionalization of nanoparticles enable early detection, diagnosis, imaging and treatment of lung cancer. The authors have elaborately presented how various nanoparticles (natural, semi synthetic and synthetic) may help in the treatment of lung cancer. They have also detailed works of various scientists who succeeded in developing effective nanoparticles and enabled very specific lung cancer therapy without any undesirable side effects and minimized death.



Renewable Biofuels

Renewable Biofuels Author Vandana Rana
ISBN-10 9783319473796
Release 2016-12-08
Pages 106
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This book offers a complete introduction for novices to understand key concepts of biocatalysis and how to produce in-house enzymes that can be used for low-cost biofuels production. The authors discuss the challenges involved in the commercialization of the biofuel industry, given the expense of commercial enzymes used for lignocellulose conversion. They describe the limitations in the process, such as complexity of lignocellulose structure, different microbial communities’ actions and interactions for degrading the recalcitrant structure of lignocellulosic materials, hydrolysis mechanism and potential for bio refinery. Readers will gain understanding of the key concepts of microbial catalysis of lignocellulosic biomass, process complexities and selection of microbes for catalysis or genetic engineering to improve the production of bioethanol or biofuel



Teaching Environmental Health to Children

Teaching Environmental Health to Children Author David W. Hursh
ISBN-10 940071811X
Release 2012-01-14
Pages 93
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Every day we are exposed to toxins and toxicants that can impact our health. Yet we rarely teach elementary and secondary students about these exposures and how they can reduce their risk to them. In this book we highlight activities and curriculum developed at nine universities in the United States from a grant funded by the National Institute of Environmental Health Sciences. Our goal is to extend these lessons to a global audience and for classroom teachers of all subjects and age levels to include environmental health in their teaching. ‘An invaluable tool for equipping informed citizens to think about the environment and its human impacts --both the science, and equally important, the social and ethical dimensions’ , Howard Frumkin, M.D., Dr. P.H., Dean, School of Public Health, University of Washington, Seattle, WA, USA



Innovative Diagnostics and Treatment Nanorobotics and Stem Cells

Innovative Diagnostics and Treatment  Nanorobotics and Stem Cells Author Tomasz Jadczyk
ISBN-10 9789811045271
Release 2017-05-12
Pages 61
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This book focuses on nanorobotic agents and stem cells for biomedical applications.It is intended for researchers and clinicians interested in innovative diagnostic and therapeutic strategies based on nanorobots and stem cells.It presents current advances in the field of molecular machines, which could be applied to generate novel therapeutic-diagnostic systems.



How to Do Science with Models

How to Do Science with Models Author Axel Gelfert
ISBN-10 9783319279541
Release 2015-12-21
Pages 135
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Taking scientific practice as its starting point, this book charts the complex territory of models used in science. It examines what scientific models are and what their function is. Reliance on models is pervasive in science, and scientists often need to construct models in order to explain or predict anything of interest at all. The diversity of kinds of models one finds in science – ranging from toy models and scale models to theoretical and mathematical models – has attracted attention not only from scientists, but also from philosophers, sociologists, and historians of science. This has given rise to a wide variety of case studies that look at the different uses to which models have been put in specific scientific contexts. By exploring current debates on the use and building of models via cutting-edge examples drawn from physics and biology, the book provides broad insight into the methodology of modelling in the natural sciences. It pairs specific arguments with introductory material relating to the ontology and the function of models, and provides some historical context to the debates as well as a sketch of general positions in the philosophy of scientific models in the process.



One Dimensional nanostructures

One Dimensional nanostructures Author Zhenyu Li
ISBN-10 9783642364273
Release 2013-03-21
Pages 141
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One-Dimensional Nanostructures: Electrospinning Technique and Unique Nanofibers is a comprehensive book depicting the electrospinning technique and related 1D unique electrospun nanofibers. The first part of the book focuses on electrospinning technique, with chapters describing Electrospinning setup, electrospinning theories, and related working parameter. The second part of the book describes in detail specific topics on how to control the electrospun fiber properties such as how to control the fiber direction, how to control the fiber surface morphology, how to control the fiber structure, and how to construct 3D structures by electrospun fibers. The final part of the book depicts the applications of the electrospun nanofibers, with sections describing in detail specific fields such as electrospun nanofiber reinforcement, filtration, electronic devices, lithium-ion batteries, fuel cells, biomedical field, and so on. One-Dimensional Nanostructures: Electrospinning Technique and Unique Nanofibers is designed to bring state-of-the-art on electrospinning together into a single book and will be valuable resource for scientists in the electrospinning field and other scientists involved in biomedical field, mechanical field, materials, and energy field. Dr. Zhenyu Li is an associate professor at the Dept. of Chemistry, Jilin University, Changchun, P. R. China. Currently, he also holds the position in Australian Future Fibres Research & Innovation Centre, Institute for Frontier Materials, Deakin University, Geelong, Victoria, Australia. Dr. Ce Wang is a professor at the Dept. of Chemistry, Jilin University, Changchun, P. R. China.



Introduction to Printed Electronics

Introduction to Printed Electronics Author Katsuaki Suganuma
ISBN-10 9781461496250
Release 2014-01-24
Pages 124
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This book describes in detail modern technologies for printed electronics, explaining how nanotechnology and modern printing technology are merging to revolutionize electronics fabrication of thin, lightweight, large and inexpensive products. Readers will benefit from the explanations of materials, devices and circuits used to design and implement the latest applications of printed electronics, such as thin flexible OLED displays, organic solar cells, OLED lighting, smart wallpaper, sensors, logic, memory and more.