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Principles and Case Studies of Simultaneous Design

Principles and Case Studies of Simultaneous Design Author William L. Luyben
ISBN-10 9781118001646
Release 2012-02-08
Pages 336
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There are many comprehensive design books, but none of them provide a significant number of detailed economic design examples of typically complex industrial processes. Most of the current design books cover a wide variety of topics associated with process design. In addition to discussing flowsheet development and equipment design, these textbooks go into a lot of detail on engineering economics and other many peripheral subjects such as written and oral skills, ethics, "green" engineering and product design. This book presents general process design principles in a concise readable form that can be easily comprehended by students and engineers when developing effective flow sheet and control structures. Ten detailed case studies presented illustrate an in-depth and quantitative way the application of these general principles. Detailed economic steady-state designs are developed that satisfy economic criterion such as minimize total annual cost of both capital and energy or return on incremental capital investment. Complete detailed flow sheets and Aspen Plus files are provided. Then conventional PI control structures are be developed and tested for their ability to maintain product quality during disturbances. Complete Aspen Dynamics files are be provided of the dynamic simulations.



Integrated Design and Simulation of Chemical Processes

Integrated Design and Simulation of Chemical Processes Author Alexandre C. Dimian
ISBN-10 9780444627087
Release 2014-09-18
Pages 886
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This comprehensive work shows how to design and develop innovative, optimal and sustainable chemical processes by applying the principles of process systems engineering, leading to integrated sustainable processes with 'green' attributes. Generic systematic methods are employed, supported by intensive use of computer simulation as a powerful tool for mastering the complexity of physical models. New to the second edition are chapters on product design and batch processes with applications in specialty chemicals, process intensification methods for designing compact equipment with high energetic efficiency, plantwide control for managing the key factors affecting the plant dynamics and operation, health, safety and environment issues, as well as sustainability analysis for achieving high environmental performance. All chapters are completely rewritten or have been revised. This new edition is suitable as teaching material for Chemical Process and Product Design courses for graduate MSc students, being compatible with academic requirements world-wide. The inclusion of the newest design methods will be of great value to professional chemical engineers. Systematic approach to developing innovative and sustainable chemical processes Presents generic principles of process simulation for analysis, creation and assessment Emphasis on sustainable development for the future of process industries



Chemical Engineering Process Simulation

Chemical Engineering Process Simulation Author Nishanth G. Chemmangattuvalappil
ISBN-10 9780128038710
Release 2017-07-13
Pages 464
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Chemical Engineering Process Simulation is ideal for students, early career researchers, and practitioners, as it guides you through chemical processes and unit operations using the main simulation softwares that are used in the industrial sector. This book will help you predict the characteristics of a process using mathematical models and computer-aided process simulation tools, as well as model and simulate process performance before detailed process design takes place. Content coverage includes steady and dynamic simulations, the similarities and differences between process simulators, an introduction to operating units, and convergence tips and tricks. You will also learn about the use of simulation for risk studies to enhance process resilience, fault finding in abnormal situations, and for training operators to control the process in difficult situations. This experienced author team combines industry knowledge with effective teaching methods to make an accessible and clear comprehensive guide to process simulation. Ideal for students, early career researchers, and practitioners, as it guides you through chemical processes and unit operations using the main simulation softwares that are used in the industrial sector. Covers the fundamentals of process simulation, theory, and advanced applications Includes case studies of various difficulty levels to practice and apply the developed skills Features step-by-step guides to using Aspen Plus and HYSYS for process simulations available on companion site Helps readers predict the characteristics of a process using mathematical models and computer-aided process simulation tools



Aspen Plus

Aspen Plus Author Kamal I.M. Al-Malah
ISBN-10 9781119293620
Release 2016-09-21
Pages 640
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Facilitates the process of learning and later mastering Aspen Plus® with step by step examples and succinct explanations Step-by-step textbook for identifying solutions to various process engineering problems via screenshots of the Aspen Plus® platforms in parallel with the related text Includes end-of-chapter problems and term project problems Includes online exam and quiz problems for instructors that are parametrized (i.e., adjustable) so that each student will have a standalone version Includes extra online material for students such as Aspen Plus®-related files that are used in the working tutorials throughout the entire textbook



Advanced Distillation Technologies

Advanced Distillation Technologies Author Anton A. Kiss
ISBN-10 9781118544815
Release 2013-02-26
Pages 416
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Distillation has historically been the main method for separating mixtures in the chemical process industry. However, despite the flexibility and widespread use of distillation processes, they still remain extremely energy inefficient. Increased optimization and novel distillation concepts can deliver substantial benefits, not just in terms of significantly lower energy use, but also in reducing capital investment and improving eco-efficiency. While likely to remain the separation technology of choice for the next few decades, there is no doubt that distillation technologies need to make radical changes in order to meet the demands of the energy-conscious society. Advanced Distillation Technologies: Design, Control and Applications gives a deep and broad insight into integrated separations using non-conventional arrangements, including both current and upcoming process intensification technologies. It includes: Key concepts in distillation technology Principles of design, control, sizing and economics of distillation Dividing-wall column (DWC) – design, configurations, optimal operation and energy efficient and advanced control DWC applications in ternary separations, azeotropic, extractive and reactive distillation Heat integrated distillation column (HIDiC) – design, equipment and configurations Heat-pump assisted applications (MVR, TVR, AHP, CHRP, TAHP and others) Cyclic distillation technology – concepts, modeling approach, design and control issues Reactive distillation – fundamentals, equipment, applications, feasibility scheme Results of rigorous simulations in Mathworks Matlab & Simulink, Aspen Plus, Dynamics and Custom Modeler Containing abundant examples and industrial case studies, this is a unique resource that tackles the most advanced distillation technologies – all the way from the conceptual design to practical implementation. The author of Advanced Distillation Technologies, Dr. Ir. Anton A. Kiss, has been awarded the Hoogewerff Jongerenprijs 2013. Find out more (website in Dutch)...



Modeling of Chemical Kinetics and Reactor Design

Modeling of Chemical Kinetics and Reactor Design Author A. Kayode Coker
ISBN-10 0884154815
Release 2001
Pages 1096
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Selecting the best type of reactor for any particular chemical reaction, taking into consideration safety, hazard analysis, scale-up, and many other factors is essential to any industrial problem. An understanding of chemical reaction kinetics and the design of chemical reactors is key to the success of the of the chemist and the chemical engineer in such an endeavor. This valuable reference volume conveys a basic understanding of chemical reactor design methodologies, incorporating control, hazard analysis, and other topics not covered in similar texts. In addition to covering fluid mixing, the treatment of wastewater, and chemical reactor modeling, the author includes sections on safety in chemical reaction and scale-up, two topics that are often neglected or overlooked. As a real-world introduction to the modeling of chemical kinetics and reactor design, the author includes a case study on ammonia synthesis that is integrated throughout the text. The text also features an accompanying CD, which contains computer programs developed to solve modeling problems using numerical methods. Students, chemists, technologists, and chemical engineers will all benefit from this comprehensive volume. Shows readers how to select the best reactor design, hazard analysis, and safety in design methodology Features computer programs developed to solve modeling problems using numerical methods



Concurrent simultaneous Engineering

Concurrent simultaneous Engineering Author Paul G. Ranky
ISBN-10 1872631045
Release 1994
Pages 256
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"Part 0 is a simulated 3D eBook on DVD, approximately 400 screens, is an interactive browser readable multimedia electronic book, containing several important text, diagrams, images, calculations, interactive 3D & 360 degree panorama objects, video clips, spreadsheets etc., the design team needs to calculate with using their own data. Parts 1 to 3 are DVD videos taped in the USA, Europe, Hong Kong, China and Japan, illustrating the importance of industrial design with ergonomics with several examples. Key subjects introduced include the following: What is industrial design? What is ergonomics, or in other words human factors engineering? What is aesthetics and how does it fit into the subject area? What is usability, and why is this important for industrial design and ergonomics? Why is fashion, and also the cultural setting within which the particular fashion style is implemented and practiced important in industrial design with ergonomics? How does art fit into all this?, and others."--Site web de l'éditeur.



Sustainability in the Design Synthesis and Analysis of Chemical Engineering Processes

Sustainability in the Design  Synthesis and Analysis of Chemical Engineering Processes Author Gerardo Ruiz Mercado
ISBN-10 9780128020647
Release 2016-07-29
Pages 426
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Sustainability in the Design, Synthesis and Analysis of Chemical Engineering Processes is an edited collection of contributions from leaders in their field. It takes a holistic view of sustainability in chemical and process engineering design, and incorporates economic analysis and human dimensions. Ruiz-Mercado and Cabezas have brought to this book their experience of researching sustainable process design and life cycle sustainability evaluation to assist with development in government, industry and academia. This book takes a practical, step-by-step approach to designing sustainable plants and processes by starting from chemical engineering fundamentals. This method enables readers to achieve new process design approaches with high influence and less complexity. It will also help to incorporate sustainability at the early stages of project life, and build up multiple systems level perspectives. Ruiz-Mercado and Cabezas’ book is the only book on the market that looks at process sustainability from a chemical engineering fundamentals perspective. Improve plants, processes and products with sustainability in mind; from conceptual design to life cycle assessment Avoid retro fitting costs by planning for sustainability concerns at the start of the design process Link sustainability to the chemical engineering fundamentals



Production Systems Engineering Cost and Performance Optimization

Production Systems Engineering  Cost and Performance Optimization Author Richard Gustavson
ISBN-10 9780071701891
Release 2010-01-22
Pages 256
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Optimize Economic and Technological Requirements in Production System Designs This pioneering work offers proven techniques, partially created and developed at The Charles Stark Draper Laboratory, for determining optimal resource allocation and cost-effective production system designs for today’s any-volume manufacturing environments. Production Systems Engineering presents a unique methodology that synthesizes applicable technology with economic requirements for an integrated solution. Featuring real-world case studies, this authoritative resource establishes a new paradigm for the manufacturing world that can also be applied to other enterprise environments. Coverage includes: Determining an improved manufacturing system design method System design basics, time allocation, resources, costs, and quality rating Stochastic analyses added to deterministic results System configuration options Multiple disparate products produced by one system World class versus mostly manual systems Determining allowable investment Simultaneous improvement in yield and cycle-time



Thermal System Design and Simulation

Thermal System Design and Simulation Author P.L. Dhar
ISBN-10 9780128094303
Release 2016-10-25
Pages 620
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Thermal System Design and Simulation covers the fundamental analyses of thermal energy systems that enable users to effectively formulate their own simulation and optimal design procedures. This reference provides thorough guidance on how to formulate optimal design constraints and develop strategies to solve them with minimal computational effort. The book uniquely illustrates the methodology of combining information flow diagrams to simplify system simulation procedures needed in optimal design. It also includes a comprehensive presentation on dynamics of thermal systems and the control systems needed to ensure safe operation at varying loads. Designed to give readers the skills to develop their own customized software for simulating and designing thermal systems, this book is relevant for anyone interested in obtaining an advanced knowledge of thermal system analysis and design. Contains detailed models of simulation for equipment in the most commonly used thermal engineering systems Features illustrations for the methodology of using information flow diagrams to simplify system simulation procedures Includes comprehensive global case studies of simulation and optimization of thermal systems



Multiregional Clinical Trials for Simultaneous Global New Drug Development

Multiregional Clinical Trials for Simultaneous Global New Drug Development Author Joshua Chen
ISBN-10 9781498701488
Release 2016-04-21
Pages 353
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In a global clinical development strategy, multiregional clinical trials (MRCTs) are vital in the development of innovative medicines. Multiregional Clinical Trials for Simultaneous Global New Drug Development presents a comprehensive overview on the current status of conducting MRCTs in clinical development. International experts from academia, industry, and health organizations address various aspects of the important problems in global clinical development and MRCTs. The book first provides a high-level introduction to the context, motivation, opportunities, and challenges in simultaneous global clinical development using MRCTs. It then focuses on the design, monitoring, and analysis/interpretation of MRCTs. The book concludes with an examination of the latest research topics from MRCT perspectives, such as special considerations by local health authorities, health economic evaluations, benefit-risk assessment, and medical devices. Explaining how to design, conduct, and interpret MRCTs, this book will help biostatisticians working in the late-stage clinical development of medical products. It will also be useful for statisticians and clinicians in the biopharmaceutical industry, regulatory agencies, and medical research institutes.



Software Modeling and Design

Software Modeling and Design Author Hassan Gomaa
ISBN-10 9781139494731
Release 2011-02-21
Pages
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This book covers all you need to know to model and design software applications from use cases to software architectures in UML and shows how to apply the COMET UML-based modeling and design method to real-world problems. The author describes architectural patterns for various architectures, such as broker, discovery, and transaction patterns for service-oriented architectures, and addresses software quality attributes including maintainability, modifiability, testability, traceability, scalability, reusability, performance, availability, and security. Complete case studies illustrate design issues for different software architectures: a banking system for client/server architecture, an online shopping system for service-oriented architecture, an emergency monitoring system for component-based software architecture, and an automated guided vehicle for real-time software architecture. Organized as an introduction followed by several short, self-contained chapters, the book is perfect for senior undergraduate or graduate courses in software engineering and design, and for experienced software engineers wanting a quick reference at each stage of the analysis, design, and development of large-scale software systems.



Agile Principles Patterns and Practices in C

Agile Principles  Patterns  and Practices in C Author Robert C. Martin
ISBN-10 0132797143
Release 2006-07-20
Pages 768
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With the award-winning book Agile Software Development: Principles, Patterns, and Practices, Robert C. Martin helped bring Agile principles to tens of thousands of Java and C++ programmers. Now .NET programmers have a definitive guide to agile methods with this completely updated volume from Robert C. Martin and Micah Martin, Agile Principles, Patterns, and Practices in C#. This book presents a series of case studies illustrating the fundamentals of Agile development and Agile design, and moves quickly from UML models to real C# code. The introductory chapters lay out the basics of the agile movement, while the later chapters show proven techniques in action. The book includes many source code examples that are also available for download from the authors’ Web site. Readers will come away from this book understanding Agile principles, and the fourteen practices of Extreme Programming Spiking, splitting, velocity, and planning iterations and releases Test-driven development, test-first design, and acceptance testing Refactoring with unit testing Pair programming Agile design and design smells The five types of UML diagrams and how to use them effectively Object-oriented package design and design patterns How to put all of it together for a real-world project Whether you are a C# programmer or a Visual Basic or Java programmer learning C#, a software development manager, or a business analyst, Agile Principles, Patterns, and Practices in C# is the first book you should read to understand agile software and how it applies to programming in the .NET Framework.



Mixed Method Design

Mixed Method Design Author Janice M Morse
ISBN-10 9781315424521
Release 2016-07-08
Pages 194
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The use of mixed methods designs for conducting research has become a major trend in social science research. Renowned methodological experts Janice Morse and Linda Niehaus present a guide to intermediate and experienced researchers on the possibilities inherent in mixed method research. They offer the basic principles of conducting this kind of study, then examine a wide variety of design options available to the researcher, including their strengths and weaknesses and when to use them. Providing examples from a variety of disciplines, examining potential threats to validity, and showing the relationship between method and theory, the book will be a valuable addition to the methodologist’s library and a useful text in courses in research design.



Process Design Principles

Process Design Principles Author Warren D. Seider
ISBN-10 STANFORD:36105022121458
Release 1999
Pages 824
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One of the most important objective in this text describes the strategies and approaches for the design of chemical processes. It covers economic (optimization) and environmental issues. The latest design strategies are described, most of which have been improved significantly with the advent of computers, mathematical programming methods, and artificial intelligence. Various methods are utilized to perform the extensive calculations and provide graphical results that are visualized easily, including the usage of computer programs for simulation and design optimization.



Designing Social Inquiry

Designing Social Inquiry Author Gary King
ISBN-10 1400821215
Release 1994-05-02
Pages 264
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While heated arguments between practitioners of qualitative and quantitative research have begun to test the very integrity of the social sciences, Gary King, Robert Keohane, and Sidney Verba have produced a farsighted and timely book that promises to sharpen and strengthen a wide range of research performed in this field. These leading scholars, each representing diverse academic traditions, have developed a unified approach to valid descriptive and causal inference in qualitative research, where numerical measurement is either impossible or undesirable. Their book demonstrates that the same logic of inference underlies both good quantitative and good qualitative research designs, and their approach applies equally to each. Providing precepts intended to stimulate and discipline thought, the authors explore issues related to framing research questions, measuring the accuracy of data and uncertainty of empirical inferences, discovering causal effects, and generally improving qualitative research. Among the specific topics they address are interpretation and inference, comparative case studies, constructing causal theories, dependent and explanatory variables, the limits of random selection, selection bias, and errors in measurement. Mathematical notation is occasionally used to clarify concepts, but no prior knowledge of mathematics or statistics is assumed. The unified logic of inference that this book explicates will be enormously useful to qualitative researchers of all traditions and substantive fields.



Quality by Design for Biopharmaceuticals

Quality by Design for Biopharmaceuticals Author Anurag S. Rathore
ISBN-10 9781118210918
Release 2011-09-20
Pages 312
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The concepts, applications, and practical issues of Quality by Design Quality by Design (QbD) is a new framework currently being implemented by the FDA, as well as EU and Japanese regulatory agencies, to ensure better understanding of the process so as to yield a consistent and high-quality pharmaceutical product. QbD breaks from past approaches in assuming that drug quality cannot be tested into products; rather, it must be built into every step of the product creation process. Quality by Design: Perspectives and Case Studies presents the first systematic approach to QbD in the biotech industry. A comprehensive resource, it combines an in-depth explanation of basic concepts with real-life case studies that illustrate the practical aspects of QbD implementation. In this single source, leading authorities from the biotechnology industry and the FDA discuss such topics as: The understanding and development of the product's critical quality attributes (CQA) Development of the design space for a manufacturing process How to employ QbD to design a formulation process Raw material analysis and control strategy for QbD Process Analytical Technology (PAT) and how it relates to QbD Relevant PAT tools and applications for the pharmaceutical industry The uses of risk assessment and management in QbD Filing QbD information in regulatory documents The application of multivariate data analysis (MVDA) to QbD Filled with vivid case studies that illustrate QbD at work in companies today, Quality by Design is a core reference for scientists in the biopharmaceutical industry, regulatory agencies, and students.