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Principles and Case Studies of Simultaneous Design

Principles and Case Studies of Simultaneous Design Author William L. Luyben
ISBN-10 9781118001646
Release 2012-02-08
Pages 336
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There are many comprehensive design books, but none of them provide a significant number of detailed economic design examples of typically complex industrial processes. Most of the current design books cover a wide variety of topics associated with process design. In addition to discussing flowsheet development and equipment design, these textbooks go into a lot of detail on engineering economics and other many peripheral subjects such as written and oral skills, ethics, "green" engineering and product design. This book presents general process design principles in a concise readable form that can be easily comprehended by students and engineers when developing effective flow sheet and control structures. Ten detailed case studies presented illustrate an in-depth and quantitative way the application of these general principles. Detailed economic steady-state designs are developed that satisfy economic criterion such as minimize total annual cost of both capital and energy or return on incremental capital investment. Complete detailed flow sheets and Aspen Plus files are provided. Then conventional PI control structures are be developed and tested for their ability to maintain product quality during disturbances. Complete Aspen Dynamics files are be provided of the dynamic simulations.



Modeling of Chemical Kinetics and Reactor Design

Modeling of Chemical Kinetics and Reactor Design Author A. Kayode Coker
ISBN-10 0884154815
Release 2001
Pages 1096
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Selecting the best type of reactor for any particular chemical reaction, taking into consideration safety, hazard analysis, scale-up, and many other factors is essential to any industrial problem. An understanding of chemical reaction kinetics and the design of chemical reactors is key to the success of the of the chemist and the chemical engineer in such an endeavor. This valuable reference volume conveys a basic understanding of chemical reactor design methodologies, incorporating control, hazard analysis, and other topics not covered in similar texts. In addition to covering fluid mixing, the treatment of wastewater, and chemical reactor modeling, the author includes sections on safety in chemical reaction and scale-up, two topics that are often neglected or overlooked. As a real-world introduction to the modeling of chemical kinetics and reactor design, the author includes a case study on ammonia synthesis that is integrated throughout the text. The text also features an accompanying CD, which contains computer programs developed to solve modeling problems using numerical methods. Students, chemists, technologists, and chemical engineers will all benefit from this comprehensive volume. Shows readers how to select the best reactor design, hazard analysis, and safety in design methodology Features computer programs developed to solve modeling problems using numerical methods



Tools For Chemical Product Design

Tools For Chemical Product Design Author Mariano Martín Martín
ISBN-10 9780444636843
Release 2016-09-19
Pages 700
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Tools for Chemical Product Design: From Consumer Products to Biomedicine describes the challenges involved in systematic product design across a variety of industries and provides a comprehensive overview of mathematical tools aimed at the design of chemical products, from molecular design to customer products. Chemical product design has become increasingly important over the past decade and includes a wide range of sectors including gasoline additives and blends in the petroleum industry, active ingredients and excipients in the pharmaceutical industry, and a variety of consumer products and specialty chemicals. Traditionally, such products have been designed through trial and error methods, which not only are time-consuming, but more importantly only provide limited knowledge that can be translated into next generation products. Features an impressive collection of contributions from leading researchers in the field Presents the latest tools available across a variety of industries Describes the challenges involved in systematic product design as well as the latest methods for solving such problems Covers a wide range of sectors including gasoline additives and blends in the petroleum industry, active ingredients and excipients in the pharmaceutical industry, and a variety of consumer products and specialty chemicals



Thermal System Design and Simulation

Thermal System Design and Simulation Author P.L. Dhar
ISBN-10 9780128094303
Release 2016-10-25
Pages 620
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Thermal System Design and Simulation covers the fundamental analyses of thermal energy systems that enable users to effectively formulate their own simulation and optimal design procedures. This reference provides thorough guidance on how to formulate optimal design constraints and develop strategies to solve them with minimal computational effort. The book uniquely illustrates the methodology of combining information flow diagrams to simplify system simulation procedures needed in optimal design. It also includes a comprehensive presentation on dynamics of thermal systems and the control systems needed to ensure safe operation at varying loads. Designed to give readers the skills to develop their own customized software for simulating and designing thermal systems, this book is relevant for anyone interested in obtaining an advanced knowledge of thermal system analysis and design. Contains detailed models of simulation for equipment in the most commonly used thermal engineering systems Features illustrations for the methodology of using information flow diagrams to simplify system simulation procedures Includes comprehensive global case studies of simulation and optimization of thermal systems



Integrated Design and Simulation of Chemical Processes

Integrated Design and Simulation of Chemical Processes Author Alexandre C. Dimian
ISBN-10 9780444627087
Release 2014-09-18
Pages 886
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This comprehensive work shows how to design and develop innovative, optimal and sustainable chemical processes by applying the principles of process systems engineering, leading to integrated sustainable processes with 'green' attributes. Generic systematic methods are employed, supported by intensive use of computer simulation as a powerful tool for mastering the complexity of physical models. New to the second edition are chapters on product design and batch processes with applications in specialty chemicals, process intensification methods for designing compact equipment with high energetic efficiency, plantwide control for managing the key factors affecting the plant dynamics and operation, health, safety and environment issues, as well as sustainability analysis for achieving high environmental performance. All chapters are completely rewritten or have been revised. This new edition is suitable as teaching material for Chemical Process and Product Design courses for graduate MSc students, being compatible with academic requirements world-wide. The inclusion of the newest design methods will be of great value to professional chemical engineers. Systematic approach to developing innovative and sustainable chemical processes Presents generic principles of process simulation for analysis, creation and assessment Emphasis on sustainable development for the future of process industries



Multi criteria Decision Analysis for Supporting the Selection of Engineering Materials in Product Design

Multi criteria Decision Analysis for Supporting the Selection of Engineering Materials in Product Design Author Ali Jahan
ISBN-10 9780081005415
Release 2016-02-17
Pages 252
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Multi-criteria Decision Analysis for Supporting the Selection of Engineering Materials in Product Design, Second Edition, provides readers with tactics they can use to optimally select materials to satisfy complex design problems when they are faced with the vast range of materials available. Current approaches to materials selection range from the use of intuition and experience, to more formalized computer-based methods, such as electronic databases with search engines to facilitate the materials selection process. Recently, multi-criteria decision-making (MCDM) methods have been applied to materials selection, demonstrating significant capability for tackling complex design problems. This book describes the rapidly growing field of MCDM and its application to materials selection. It aids readers in producing successful designs by improving the decision-making process. This new edition updates and expands previous key topics, including new chapters on materials selection in the context of design problem-solving and multiple objective decision-making, also presenting a significant amount of additional case studies that will aid in the learning process. Describes the advantages of Quality Function Deployment (QFD) in the materials selection process through different case studies Presents a methodology for multi-objective material design optimization that employs Design of Experiments coupled with Finite Element Analysis Supplements existing quantitative methods of materials selection by allowing simultaneous consideration of design attributes, component configurations, and types of material Provides a case study for simultaneous materials selection and geometrical optimization processes



Multiregional Clinical Trials for Simultaneous Global New Drug Development

Multiregional Clinical Trials for Simultaneous Global New Drug Development Author Joshua Chen
ISBN-10 9781498701488
Release 2016-04-21
Pages 353
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In a global clinical development strategy, multiregional clinical trials (MRCTs) are vital in the development of innovative medicines. Multiregional Clinical Trials for Simultaneous Global New Drug Development presents a comprehensive overview on the current status of conducting MRCTs in clinical development. International experts from academia, industry, and health organizations address various aspects of the important problems in global clinical development and MRCTs. The book first provides a high-level introduction to the context, motivation, opportunities, and challenges in simultaneous global clinical development using MRCTs. It then focuses on the design, monitoring, and analysis/interpretation of MRCTs. The book concludes with an examination of the latest research topics from MRCT perspectives, such as special considerations by local health authorities, health economic evaluations, benefit-risk assessment, and medical devices. Explaining how to design, conduct, and interpret MRCTs, this book will help biostatisticians working in the late-stage clinical development of medical products. It will also be useful for statisticians and clinicians in the biopharmaceutical industry, regulatory agencies, and medical research institutes.



Reaction Engineering for Pollution Prevention

Reaction Engineering for Pollution Prevention Author R.P. Hesketh
ISBN-10 0080540287
Release 2000-02-09
Pages 332
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This book defines environmental reaction engineering principles, including reactor design, for the development of processes that provide an environmental benefit. With regard to pollution prevention, the focus is primarily on new reaction and reactor technologies that minimize the production of undesirable side-products (pollutants), but the use of reaction engineering as a means of treating wastes that are produced through other means is also considered. First is a section on environmentally benign combustion. The three papers discuss methods of reducing the formation of PAHs and NOx, as well as other environmentally sensitive combustion products. The next section contains a collection of contributions that involve the use of a catalyst to support the reaction. Following this is a section on the use of supercritical fluid solvents as environmentally friendly media for chemical reactions. Finally, a series of papers is presented in which novel reactor designs are utilized to obtain product yields not possible in conventional reactor systems. These include the use of reactor-absorber systems, reactive distillation, and reactive membranes. The book concludes with a chapter contributed by the editors which discusses the educational aspects of pollution prevention. It is necessary for future generations of engineers to be trained to design processes that are inherently environmentally benign. This chapter assembles resource materials for educators which will spark the creative instincts of the researchers using the materials contained within this book to develop new resources for pollution prevention education. The broad spectrum of topics included in this book indicates the diversity of this area, and the vibrant nature of the ongoing research. The possibilities of producing desirable products without the formation of waste byproducts are bounded only by the creativity of the reaction engineer.



Handbook of Process Integration PI

Handbook of Process Integration  PI Author Jiří J Klemeš
ISBN-10 9780857097255
Release 2013-07-31
Pages 1184
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Since its first development in the 1970s, Process Integration (PI) has become an important methodology in achieving more energy efficient processes. This pioneering handbook brings together the leading scientists and researchers currently contributing to PI development, pooling their expertise and specialist knowledge to provide readers with a comprehensive and up-to-date guide to the latest PI research and applications. After an introduction to the principles of PI, the book reviews a wide range of process design and integration topics ranging from heat and utility systems to water, recycling, waste and hydrogen systems. The book considers Heat Integration, Mass Integration and Extended PI as well as a series of applications and case studies. Chapters address not just operating and capital costs but also equipment design and operability issues, through to buildings and supply chains. With its distinguished editor and international team of expert contributors, Handbook of Process Integration (PI) is a standard reference work for managers and researchers in all energy-intensive industries, as well as academics with an interest in them, including those designing and managing oil refineries, petrochemical and power plants, as well as paper/pulp, steel, waste, food and drink processors. This pioneering handbook provides a comprehensive and up-to-date guide to the latest process integration research and applications Reviews a wide range of process design and integration topics ranging from heat and utility systems to water, recycling, waste and hydrogen systems Chapters also address equipment design and operability issues, through to buildings and supply chains



Chemical Engineering Process Simulation

Chemical Engineering Process Simulation Author Nishanth G. Chemmangattuvalappil
ISBN-10 9780128038710
Release 2017-07-13
Pages 464
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Chemical Engineering Process Simulation is ideal for students, early career researchers, and practitioners, as it guides you through chemical processes and unit operations using the main simulation softwares that are used in the industrial sector. This book will help you predict the characteristics of a process using mathematical models and computer-aided process simulation tools, as well as model and simulate process performance before detailed process design takes place. Content coverage includes steady and dynamic simulations, the similarities and differences between process simulators, an introduction to operating units, and convergence tips and tricks. You will also learn about the use of simulation for risk studies to enhance process resilience, fault finding in abnormal situations, and for training operators to control the process in difficult situations. This experienced author team combines industry knowledge with effective teaching methods to make an accessible and clear comprehensive guide to process simulation. Ideal for students, early career researchers, and practitioners, as it guides you through chemical processes and unit operations using the main simulation softwares that are used in the industrial sector. Covers the fundamentals of process simulation, theory, and advanced applications Includes case studies of various difficulty levels to practice and apply the developed skills Features step-by-step guides to using Aspen Plus and HYSYS for process simulations available on companion site Helps readers predict the characteristics of a process using mathematical models and computer-aided process simulation tools



Aspen Plus

Aspen Plus Author Kamal I.M. Al-Malah
ISBN-10 9781119293620
Release 2016-09-21
Pages 640
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Facilitates the process of learning and later mastering Aspen Plus® with step by step examples and succinct explanations Step-by-step textbook for identifying solutions to various process engineering problems via screenshots of the Aspen Plus® platforms in parallel with the related text Includes end-of-chapter problems and term project problems Includes online exam and quiz problems for instructors that are parametrized (i.e., adjustable) so that each student will have a standalone version Includes extra online material for students such as Aspen Plus®-related files that are used in the working tutorials throughout the entire textbook



Sustainability in the Design Synthesis and Analysis of Chemical Engineering Processes

Sustainability in the Design  Synthesis and Analysis of Chemical Engineering Processes Author Gerardo Ruiz Mercado
ISBN-10 9780128020647
Release 2016-07-29
Pages 426
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Sustainability in the Design, Synthesis and Analysis of Chemical Engineering Processes is an edited collection of contributions from leaders in their field. It takes a holistic view of sustainability in chemical and process engineering design, and incorporates economic analysis and human dimensions. Ruiz-Mercado and Cabezas have brought to this book their experience of researching sustainable process design and life cycle sustainability evaluation to assist with development in government, industry and academia. This book takes a practical, step-by-step approach to designing sustainable plants and processes by starting from chemical engineering fundamentals. This method enables readers to achieve new process design approaches with high influence and less complexity. It will also help to incorporate sustainability at the early stages of project life, and build up multiple systems level perspectives. Ruiz-Mercado and Cabezas’ book is the only book on the market that looks at process sustainability from a chemical engineering fundamentals perspective. Improve plants, processes and products with sustainability in mind; from conceptual design to life cycle assessment Avoid retro fitting costs by planning for sustainability concerns at the start of the design process Link sustainability to the chemical engineering fundamentals



Elementary Principles of Chemical Processes

Elementary Principles of Chemical Processes Author Richard Mark Felder
ISBN-10 0470824964
Release 2009-05-07
Pages 704
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Elementary Principles of Chemical Processes has been writing in one form or another for most of life. You can find so many inspiration from Elementary Principles of Chemical Processes also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Elementary Principles of Chemical Processes book for free.



Design of Hybrid Molecules for Drug Development

Design of Hybrid Molecules for Drug Development Author Michael Decker
ISBN-10 9780081011188
Release 2017-04-05
Pages 352
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Design of Hybrid Molecules for Drug Development reviews the principles, advantages, and limitations involved with designing these groundbreaking compounds. Beginning with an introduction to hybrid molecule design and background as to their need, the book goes on to explore a range of important hybrids, with hybrids containing natural products, molecules containing NO- and H2S-donors, dual-acting compounds acting as receptor ligands and enzyme inhibitors, and the design of photoresponsive drugs all discussed. Drawing on practical case studies, the hybridization of molecules for development as treatments for a number of key diseases is then outlined, including the design of hybrids for Alzheimer's, cancer, and malaria. With its cutting-edge reviews of breaking developments in this exciting field, the book offers a novel approach for all those working in the design, development, and administration of drugs for a range of debilitating disorders. Highlights an approach unimpaired by the limitations of the classical search for lead structures - one of the core problems in modern drug development processes, making the content of high relevance for both academic and non-academic drug development processes Pulls together research and design techniques in a novel way to give researchers the best possible platform from which to review the approaches and techniques applied Compares the advantages and disadvantages of these compounds Includes the very latest developments, such as photoactivatable and photo-responsive drugs



Principles of Chemical Engineering Processes

Principles of Chemical Engineering Processes Author Nayef Ghasem
ISBN-10 9781482222289
Release 2014-11-10
Pages 468
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Principles of Chemical Engineering Processes: Material and Energy Balances introduces the basic principles and calculation techniques used in the field of chemical engineering, providing a solid understanding of the fundamentals of the application of material and energy balances. Packed with illustrative examples and case studies, this book: Discusses problems in material and energy balances related to chemical reactors Explains the concepts of dimensions, units, psychrometry, steam properties, and conservation of mass and energy Demonstrates how MATLAB® and Simulink® can be used to solve complicated problems of material and energy balances Shows how to solve steady-state and transient mass and energy balance problems involving multiple-unit processes and recycle, bypass, and purge streams Develops quantitative problem-solving skills, specifically the ability to think quantitatively (including numbers and units), the ability to translate words into diagrams and mathematical expressions, the ability to use common sense to interpret vague and ambiguous language in problem statements, and the ability to make judicious use of approximations and reasonable assumptions to simplify problems This Second Edition has been updated based upon feedback from professors and students. It features a new chapter related to single- and multiphase systems and contains additional solved examples and homework problems. Educational software, downloadable exercises, and a solutions manual are available with qualifying course adoption.



21st European Symposium on Computer Aided Process Engineering

21st European Symposium on Computer Aided Process Engineering Author E. N. Pistikopoulos
ISBN-10 9780444538956
Release 2011-05-26
Pages 2029
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The European Symposium on Computer Aided Process Engineering (ESCAPE) series presents the latest innovations and achievements of leading professionals from the industrial and academic communities. The ESCAPE series serves as a forum for engineers, scientists, researchers, managers and students to present and discuss progress being made in the area of Computer Aided Process Engineering (CAPE). European industries large and small are bringing innovations into our lives, whether in the form of new technologies to address environmental problems, new products to make our homes more comfortable and energy efficient or new therapies to improve the health and well-being of European citizens. Moreover, the European Industry needs to undertake research and technological initiatives in response to humanity's "Grand Challenges", described in the declaration of Lund, namely, Global Warming, Tightening Supplies of Energy, Water and Food, Ageing Societies, Public Health, Pandemics and Security. Thus, the Technical Theme of ESCAPE 21 will be "Process Systems Approaches for Addressing Grand Challenges in Energy, Environment, Health, Bioprocessing & Nanotechnologies".



11th International Symposium on Process Systems Engineering PSE2012

11th International Symposium on Process Systems Engineering   PSE2012 Author
ISBN-10 9780444595089
Release 2012-12-31
Pages 1800
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While the PSE community continues its focus on understanding, synthesizing, modeling, designing, simulating, analyzing, diagnosing, operating, controlling, managing, and optimizing a host of chemical and related industries using the systems approach, the boundaries of PSE research have expanded considerably over the years. While early PSE research was largely concerned with individual units and plants, the current research spans wide ranges of scales in size (molecules to processing units to plants to global multinational enterprises to global supply chain networks; biological cells to ecological webs) and time (instantaneous molecular interactions to months of plant operation to years of strategic planning). The changes and challenges brought about by increasing globalization and the the common global issues of energy, sustainability, and environment provide the motivation for the theme of PSE2012: Process Systems Engineering and Decision Support for the Flat World. Each theme includes an invited chapter based on the plenary presentation by an eminent academic or industrial researcher Reports on the state-of-the-art advances in the various fields of process systems engineering Addresses common global problems and the research being done to solve them