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Regenerative Engineering of Musculoskeletal Tissues and Interfaces

Regenerative Engineering of Musculoskeletal Tissues and Interfaces Author Syam Nukavarapu
ISBN-10 9781782423140
Release 2015-04-24
Pages 462
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Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cells, growth factors, and mechanical forces, moving on to discuss tissue-engineering strategies for bone, tendon, ligament, cartilage, meniscus, and muscle, as well as progress and advances in tissue vascularization and nerve innervation of the individual tissues. Final chapters present information on musculoskeletal tissue interfaces. Comprehensive review of the repair and regeneration of musculoskeletal individual tissues and tissue interfaces Presents recent developments, fundamentals and progress in the field of engineering tissues Reviews progress and advances in tissue vascularization and innervation



Nanocomposites for Musculoskeletal Tissue Regeneration

Nanocomposites for Musculoskeletal Tissue Regeneration Author Huinan Liu
ISBN-10 9781782424758
Release 2016-02-23
Pages 406
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Nanocomposites for Musculoskeletal Tissue Regeneration discusses the advanced biomaterials scientists are exploring for use as tools to mimic the structure of musculoskeletal tissues. Bone and other musculoskeletal tissues naturally have a nanocomposite structure, therefore nanocomposites are ideally suited as a material for replacing and regenerating these natural tissues. In addition, biological properties such as biointegration and the ability to tailor and dope the materials make them highly desirable for musculoskeletal tissue regeneration. Provides a comprehensive discussion on the design and advancements made in the use of nanocomposites for musculoskeletal tissue regeneration Presents an In-depth coverage of material properties Includes discussions on polymers, ceramics, and glass



Nanocomposites for Musculoskeletal Tissue Regeneration

Nanocomposites for Musculoskeletal Tissue Regeneration Author Huinan Liu
ISBN-10 9781782424758
Release 2016-02-23
Pages 406
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Nanocomposites for Musculoskeletal Tissue Regeneration discusses the advanced biomaterials scientists are exploring for use as tools to mimic the structure of musculoskeletal tissues. Bone and other musculoskeletal tissues naturally have a nanocomposite structure, therefore nanocomposites are ideally suited as a material for replacing and regenerating these natural tissues. In addition, biological properties such as biointegration and the ability to tailor and dope the materials make them highly desirable for musculoskeletal tissue regeneration. Provides a comprehensive discussion on the design and advancements made in the use of nanocomposites for musculoskeletal tissue regeneration Presents an In-depth coverage of material properties Includes discussions on polymers, ceramics, and glass



Nanomaterials in Tissue Engineering

Nanomaterials in Tissue Engineering Author A K Gaharwar
ISBN-10 9780857097231
Release 2013-07-31
Pages 468
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Nanomaterial technologies can be used to fabricate high-performance biomaterials with tailored physical, chemical, and biological properties. They are therefore an area of interest for emerging biomedical technologies such as scaffolding, tissue regeneration, and controlled drug delivery. Nanomaterials in tissue engineering explores the fabrication of a variety of nanomaterials and the use of these materials across a range of tissue engineering applications. Part one focuses on the fabrication of nanomaterials for tissue engineering applications and includes chapters on engineering nanoporous biomaterials, layer-by-layer self-assembly techniques for nanostructured devices, and the synthesis of carbon based nanomaterials. Part two goes on to highlight the application of nanomaterials in soft tissue engineering and includes chapters on cardiac, neural, and cartilage tissue engineering. Finally, the use of nanomaterials in hard tissue engineering applications, including bone, dental and craniofacial tissue engineering is discussed in part three. Nanomaterials in tissue engineering is a standard reference for researchers and tissue engineers with an interest in nanomaterials, laboratories investigating biomaterials, and academics interested in materials science, chemical engineering, biomedical engineering and biological sciences. Explores the fabrication of a variety of nanomaterials and their use across a range of tissue engineering applications Examines engineering nanoporous biomaterials, layer-by-layer self-assembly techniques for nanostructured devices, and the synthesis of carbon based nanomaterials Highlights the application of nanomaterials in soft tissue engineering and includes chapters on cardiac, neural, and cartilage tissue engineering



Biomaterials and Regenerative Medicine in Ophthalmology

Biomaterials and Regenerative Medicine in Ophthalmology Author Traian Chirila
ISBN-10 9780081001844
Release 2016-04-23
Pages 502
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Biomaterials and Regenerative Medicine in Ophthalmology, Second Edition, focuses on an aging population and the increasing instances of eye diseases. Biomaterials continue to be used for numerous medical devices for the restoration of eyesight, improving many patients’ quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. This book provides readers with an updated and expanded look at the present status and future direction of biomaterials and regenerative medicine in this important field. Provides an integral and significant exploration of biomaterials and regenerative medicine, presenting crucial advances made in the fields of ophthalmology and optometry, such as the development of intraocular lenses and new applications for contact lens Presents a new and updated look at the future direction of biomaterials and regenerative medicine in this field Comprehensive coverage in a range of fields, including hydrogels, corneal tissue engineering, and stem cell therapies for the restoration of the ocular surface



Regenerative Medicine and Biomaterials for the Repair of Connective Tissues

Regenerative Medicine and Biomaterials for the Repair of Connective Tissues Author Charles Archer
ISBN-10 9781845697792
Release 2010-01-12
Pages 504
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Regenerative medicine for the repair of connective tissues is a fast moving field which generates a lot of interest. Unfortunately the biomaterials and biomechanics for soft tissue repair has been under-represented in the past. Particularly the natural association between cartilage, tendons and ligaments is often not made. Regenerative medicine and biomaterials for the repair of connective tissues addresses this gap in the market by bringing together the natural association of cartilage, tendons and ligaments to provide a review of the different structures, biomechanics and, more importantly, provide a clear discussion of practical techniques and biomaterials which may be used to repair the connective tissues. Part one discusses cartilage repair and regeneration with chapters on such topics as structure, biomechanics and repair of cartilage. Chapters in Part two focus on the repair of tendons on ligaments with particular techniques including cell-based therapies for the repair and regeneration of tendons and ligaments and scaffolds for tendon and ligament tissue engineering. Addresses the natural association between cartilage, tendons and ligaments which is often not made Provides a review of the different structures, biomechanics and practical techniques which are used in the repair of connective tissues Chapters focus on such areas as cartilage repair and regeneration, the repair of tendons and ligaments, investigating techniques including scaffolds and cell-based therapies



Wound Healing Biomaterials Volume 2

Wound Healing Biomaterials   Volume 2 Author Magnus Ågren
ISBN-10 9780081006061
Release 2016-05-30
Pages 542
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Wound Healing Biomaterials: Volume Two, Functional Biomaterials discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal wounds opening up a new area of research in biomaterials and the ways they can be applied to the challenges associated with wound care. Much research is now concerned with new therapies, regeneration methods, and the use of biomaterials that can assist in wound healing and alter healing responses. This book provides readers with a thorough review of the functional biomaterials used for wound healing, with chapters discussing the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and functional dressings for wound care. Includes more systematic and comprehensive coverage on the topic of wound care Provides thorough coverage of all specific therapies and biomaterials for wound healing Contains clear layout and organization that is carefully arranged with clear titles and comprehensive section headings Details specific sections on the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and more



Chitosan Based Biomaterials Volume 2

Chitosan Based Biomaterials Volume 2 Author Jessica Amber Jennings
ISBN-10 9780081002568
Release 2016-09-28
Pages 296
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Chitosan Based Biomaterials: Tissue Engineering and Therapeutics, Volume 2, provides the latest information on chitosan, a natural polymer derived from the marine material chitin. Chitosan displays unique properties, most notably biocompatibility and biodegradability. It can also be easily tuned to modify its structure or properties, making chitosan an excellent candidate as a biomaterial. Consequently, chitosan is being developed for many biomedical functions, ranging from tissue engineering and implant coatings to drug and gene delivery. This book provides readers with a full coverage of the applications of chitosan-based biomaterials. Presents specific focus on tissue engineering and therapeutics Provides comprehensive treatment of all biomaterial applications of chitosan Contains contributions by leading researchers with extensive experience in the material



Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System

Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System Author Z Jin
ISBN-10 9780857096739
Release 2014-05-05
Pages 550
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Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System reviews how a wide range of materials are modelled and how this modelling is applied. Computational modelling is increasingly important in the design and manufacture of biomedical materials, as it makes it possible to predict certain implant-tissue reactions, degradation, and wear, and allows more accurate tailoring of materials' properties for the in vivo environment. Part I introduces generic modelling of biomechanics and biotribology with a chapter on the fundamentals of computational modelling of biomechanics in the musculoskeletal system, and a further chapter on finite element modelling in the musculoskeletal system. Chapters in Part II focus on computational modelling of musculoskeletal cells and tissues, including cell mechanics, soft tissues and ligaments, muscle biomechanics, articular cartilage, bone and bone remodelling, and fracture processes in bones. Part III highlights computational modelling of orthopedic biomaterials and interfaces, including fatigue of bone cement, fracture processes in orthopedic implants, and cementless cup fixation in total hip arthroplasty (THA). Finally, chapters in Part IV discuss applications of computational modelling for joint replacements and tissue scaffolds, specifically hip implants, knee implants, and spinal implants; and computer aided design and finite element modelling of bone tissue scaffolds. This book is a comprehensive resource for professionals in the biomedical market, materials scientists and mechanical engineers, and those in academia. Covers generic modelling of cells and tissues; modelling of biomaterials and interfaces; biomechanics and biotribology Discusses applications of modelling for joint replacements and applications of computational modelling in tissue engineering



Bone Repair Biomaterials

Bone Repair Biomaterials Author J A Planell
ISBN-10 9781845696610
Release 2009-08-26
Pages 496
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Bone repair is a fundamental part of the rapidly expanding medical care sector and has benefited from many recent technological developments. With an increasing number of technologies available, it is vital that the correct technique is selected for specific clinical procedures. This unique book will provide a comprehensive review of the materials science, engineering principles and recent advances in this important area. The first part of the book reviews the fundamentals of bone repair and regeneration. Chapters in the second part discuss the science and properties of biomaterials used for bone repair such as metals, ceramics, polymers and composites. The final section of the book discusses clinical applications and considerations with chapters on such topics as orthopaedic surgery, tissue engineering, implant retrieval and ethics of bone repair biomaterials. With its distinguished editors and team of international contributors, Bone repair biomaterials is an invaluable reference for researchers and clinicians within the biomedical industry and academia. Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area Reviews the fundamentals of bone repair and regeneration addressing social, economic and clinical challenges Examines the properties of biomaterials used for bone repair with specific chapters assessing metals, ceramics, polymers and composites



Regenerative Engineering

Regenerative Engineering Author Yusuf Khan
ISBN-10 9781351647397
Release 2018-04-19
Pages 154
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This book focuses on both advances in materials science and in scaffold development techniques, paying close attention to state-of-the-art research. Each chapter will delve into specific materials categories (e.g. composite materials, bioactive ceramics, etc.) and how these materials are specifically designed for regenerative engineering applications. There will also be unique chapters on Biologically Derived Scaffolding along with 3-D Printing Technology for Regenerative Engineeering.



Hydroxyapatite HAp for Biomedical Applications

Hydroxyapatite  HAp  for Biomedical Applications Author Michael Mucalo
ISBN-10 9781782420415
Release 2015-03-06
Pages 404
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Hydroxyapatite in the form of hydroxycarbonate apatite is the principal mineral component of bone tissue in mammals. In Bioceramics, it is classed as a bioactive material, which means bone tissue grows directly on it when placed in apposition without intervening fibrous tissue. Hydroxyapatite is hence commonly used as bone grafts, fillers and as coatings for metal implants. This important book provides an overview of the most recent research and developments involving hydroxyapatite as a key material in medicine and its application. Reviews the important properties of hydroxyapatite as a biomaterial Considers a range of specific forms of the material and their advantages Reviews a range of specific medical applications for this important material



Nanotechnology Applications for Tissue Engineering

Nanotechnology Applications for Tissue Engineering Author Sabu Thomas
ISBN-10 9780323353038
Release 2015-01-03
Pages 336
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Tissue engineering involves seeding of cells on bio-mimicked scaffolds providing adhesive surfaces. Researchers though face a range of problems in generating tissue which can be circumvented by employing nanotechnology. It provides substrates for cell adhesion and proliferation and agents for cell growth and can be used to create nanostructures and nanoparticles to aid the engineering of different types of tissue. Written by renowned scientists from academia and industry, this book covers the recent developments, trends and innovations in the application of nanotechnologies in tissue engineering and regenerative medicine. It provides information on methodologies for designing and using biomaterials to regenerate tissue, on novel nano-textured surface features of materials (nano-structured polymers and metals e.g.) as well as on theranostics, immunology and nano-toxicology aspects. In the book also explained are fabrication techniques for production of scaffolds to a series of tissue-specific applications of scaffolds in tissue engineering for specific biomaterials and several types of tissue (such as skin bone, cartilage, vascular, cardiac, bladder and brain tissue). Furthermore, developments in nano drug delivery, gene therapy and cancer nanotechonology are described. The book helps readers to gain a working knowledge about the nanotechnology aspects of tissue engineering and will be of great use to those involved in building specific tissue substitutes in reaching their objective in a more efficient way. It is aimed for R&D and academic scientists, lab engineers, lecturers and PhD students engaged in the fields of tissue engineering or more generally regenerative medicine, nanomedicine, medical devices, nanofabrication, biofabrication, nano- and biomaterials and biomedical engineering. Provides state-of-the-art knowledge on how nanotechnology can help tackling known problems in tissue engineering Covers materials design, fabrication techniques for tissue-specific applications as well as immunology and toxicology aspects Helps scientists and lab engineers building tissue substitutes in a more efficient way



Biomaterials and Medical Devices

Biomaterials and Medical Devices Author Ferdiansyah Mahyudin
ISBN-10 9783319148458
Release 2016-03-29
Pages 242
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This book presents an introduction to biomaterials with the focus on the current development and future direction of biomaterials and medical devices research and development in Indonesia. It is the first biomaterials book written by selected academic and clinical experts experts on biomaterials and medical devices from various institutions and industries in Indonesia. It serves as a reference source for researchers starting new projects, for companies developing and marketing products and for governments setting new policies. Chapter one covers the fundamentals of biomaterials, types of biomaterials, their structures and properties and the relationship between them. Chapter two discusses unconventional processing of biomaterials including nano-hybrid organic-inorganic biomaterials. Chapter three addresses biocompatibility issues including in vitro cytotoxicity, genotoxicity, in vitro cell models, biocompatibility data and its related failure. Chapter four describes degradable biomaterial for medical implants, which include biodegradable polymers, biodegradable metals, degradation assessment techniques and future directions. Chapter five focuses on animal models for biomaterial research, ethics, care and use, implantation study and monitoring and studies on medical implants in animals in Indonesia. Chapter six covers biomimetic bioceramics, natural-based biocomposites and the latest research on natural-based biomaterials in Indonesia. Chapter seven describes recent advances in natural biomaterial from human and animal tissue, its processing and applications. Chapter eight discusses orthopedic applications of biomaterials focusing on most common problems in Indonesia, and surgical intervention and implants. Chapter nine describes biomaterials in dentistry and their development in Indonesia.



Nanotechnology and Tissue Engineering

Nanotechnology and Tissue Engineering Author Cato T. Laurencin
ISBN-10 1420051830
Release 2008-06-16
Pages 384
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Nanofabrication gives us the ability to mimic biological structures with molecular level precision. Offering a natural progression of topics, Nanotechnology and Tissue Engineering: The Scaffold provides a state-of-the-art account of groundbreaking research in this rapidly emerging area of biomedical engineering. Emphasizing the importance of scaffolds, the book details fundamental and advanced aspects of nanofabrication and examines cellular interactions at the nanoscale level. It reviews extracellular matrix structure and function and discusses various nanoscale biological surface modifications that can improve cellular responses. The editors present the most promising nanofabrication techniques, including electrospinning, lithography, and self assembly. Featuring the contributions of pioneering scientists writing about their own research, this cutting-edge volume — Provides background information discussing the emerging importance of scaffolds in tissue engineering Examines tissue engineering as it relates to orthopedic, cardiovascular, neural, and musculoskeletal applications Details cell responses to a number of nanoscale features Delves into microfabrication techniques in scaffold development Presents research on designer self-assembling peptide scaffolds This highly comprehensive resource also discusses clinical implications and applications, presenting exciting breakthroughs in neural, vascular, and musculoskeletal tissue engineering with nanostructures. An essential resource, for biomedical engineers working on the frontiers of tissue research, this book brings together current findings and background information on a complete range of engineering processes that have led to the development of a number of highly useful tissues.



Introduction to Biomaterials

Introduction to Biomaterials Author J. L. Ong
ISBN-10 9780521116909
Release 2013-11-07
Pages 419
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A succinct introduction to the field of biomaterials engineering, packed with practical insights.



Biomimetic Research for Architecture and Building Construction

Biomimetic Research for Architecture and Building Construction Author Jan Knippers
ISBN-10 9783319463742
Release 2017-01-17
Pages 408
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This book comprises a first survey of the Collaborative Research Center SFB-TRR 141 ‘Biological Design and Integrative Structures – Analysis, Simulation and Implementation in Architecture’, funded by the Deutsche Forschungsgemeinschaft since October 2014. The SFB-TRR 141 provides a collaborative framework for architects and engineers from the University of Stuttgart, biologists and physicists from the University of Freiburg and geoscientists and evolutionary biologists from the University of Tübingen. The programm is conceptualized as a dialogue between the disciplines and is based on the belief that that biomimetic research has the potential to lead everyone involved to new findings far beyond his individual reach. During the last few decades, computational methods have been introduced into all fields of science and technology. In architecture, they enable the geometric differentiation of building components and allow the fabrication of porous or fibre-based materials with locally adjusted physical and chemical properties. Recent developments in simulation technologies focus on multi-scale models and the interplay of mechanical phenomena at various hierarchical levels. In the natural sciences, a multitude of quantitative methods covering diverse hierarchical levels have been introduced. These advances in computational methods have opened a new era in biomimetics: local differentiation at various scales, the main feature of natural constructions, can for the first time not only be analysed, but to a certain extent also be transferred to building construction. Computational methodologies enable the direct exchange of information between fields of science that, until now, have been widely separated. As a result they lead to a new approach to biomimetic research, which, hopefully, contributes to a more sustainable development in architecture and building construction.