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Sperm Acrosome Biogenesis and Function During Fertilization

Sperm Acrosome Biogenesis and Function During Fertilization Author Mariano G. Buffone
ISBN-10 9783319305677
Release 2016-05-19
Pages 172
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Over the last decades, acrosomal exocytosis (also called the “acrosome reaction”) has been recognized as playing an essential role in fertilization. Secretion of this granule is an absolute requirement for physiological fertilization. In recent years, the study of mammalian acrosomal exocytosis has yielded some major advances that challenge the long-held, general paradigms in the field. Principally, the idea that sperm must be acrosome-intact to bind to the zona pellucida of unfertilized eggs, based largely on in vitro fertilization studies of mouse oocytes denuded of the cumulus oophorus, has been overturned by experiments using state-of-the-art imaging of cumulus-intact oocytes and fertilization experiments where eggs were reinseminated by acrosome-reacted sperm recovered from the perivitelline space of zygotes. From a molecular point of view, acrosome exocytosis is a synchronized and tightly regulated process mediated by molecular mechanisms that are homologous to those reported in neuroendocrinal cell secretions. The authors provide a broader perspective, focusing on a limited number of important topics that are essential for understanding the molecular mechanisms governing this step in the fertilization process. They also discuss molecular aspects such as the signaling pathways leading to exocytosis, including the participation of ion channels, lipids, the fusion machinery proteins and the actin cytoskeleton as well as cellular aspects such as the site of acrosomal exocytosis and the use of gene-manipulated animals to study this process.



Nuevos y antiguos retos de la espermatolog a veterinaria

Nuevos y antiguos retos de la espermatolog  a veterinaria Author José Julián Garde López-Brea
ISBN-10
Release
Pages 120
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La Espermatología engloba el estudio científico de los espermatozoides y de las secreciones seminales, analizando entre otros, aspectos relativos a su Histología, Fisiología y Embriología. Igualmente contempla la aplicación de los diferentes procesos tecnológicos que permiten el empleo y la manipulación de los gametos masculinos por medio de las diferentes técnicas de reproducción asistida. La Espermatología Veterinaria hace referencia a la aplicada al estudio, conservación y manipulación de los gametos masculinos de las especies de interés ganadero o zootécnico.



Dynamics of the Mammalian Sperm Head

Dynamics of the Mammalian Sperm Head Author Kiyotaka Toshimori
ISBN-10 3540899790
Release 2009-04-28
Pages 98
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Mammalian spermatozoa have complex structures. The structure-function relationship of sperm has been studied from various viewpoints. Accumulated evidence has shown that the sperm components undergo sequential changes from the beginning of spermatogenesis to the time of fertilization/embryogenesis. Structural analyses have been performed using various new techniques of light and electron microscopy as well as immunohistochemistry and immunocytochemistry in combination with specific probes such as antibodies against sperm components. Recently developed gene-manipulation techniques have accelerated investigations on the events that govern the relationship between the structure and molecular components of sperm. In addition, animal models with gene manipulations have been shown to exhibit various morphological and functional abnormalities that lead to infertility. In this book, I discuss the events that occur in the normal sperm head and govern the structure-function relationship from the time of spermatogenesis to that of fertilization or egg activation. In this regard, I describe dynamic modifications and maturation events occurring in sperm-head components and compare the outcomes of these events with the outcomes of their failure.



Introduction to Mammalian Reproduction

Introduction to Mammalian Reproduction Author Daulat Tulsiani
ISBN-10 9781461502739
Release 2012-12-06
Pages 403
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Introduction to Mammalian Reproduction is a welcome contribution to the fields of gametogenesis, gamete transport, fertilization, and reproduction technologies. Key topics covered include: *formation and maturation of male gametes; *morphology and physiology of female gametes; *how the sperm meets the egg; *sperm-egg fusion, egg activation, and implantation of fertilized egg; *assisted reproduction and environmental chemicals that have an effect on formation and function of male and female gametes. This book is for both researchers and students involved in reproductive biology.



Extracellular Matrix in Development

Extracellular Matrix in Development Author Douglas W. DeSimone
ISBN-10 9783642359354
Release 2013-03-15
Pages 253
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Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.



Little Eight John

Little Eight John Author Jan Wahl
ISBN-10 0140556303
Release 1998-02-01
Pages 32
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Little Eight John, as mean as mean there was, persists in disobeying his mother until he finds his mischief backfiring on him.



Human Fertility

Human Fertility Author Zev Rosenwaks
ISBN-10 1493906585
Release 2014-04-30
Pages 584
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Human Fertility: Methods and Protocols is intended for all practitioners of reproductive medicine and ART, as well as for embryologists and reproductive, developmental, cell and molecular biologists and others in the biomedical sciences. The volume presents straight-forward manner best practice approaches for overcoming a host of fertility challenges. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Human Fertility: Methods and Protocols aids scientists in continuing to study assisted reproductive technologies.



Molecular and Functional Insights Into the Pulmonary Vasculature

Molecular and Functional Insights Into the Pulmonary Vasculature Author Kaushik Parthasarathi
ISBN-10 9783319684833
Release 2017-12-29
Pages 86
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This book provides a comprehensive review of the structure, function and pathophysiology of the pulmonary vasculature. Emerging evidence reveals the multifaceted roles played by the pulmonary vasculature. To reflect those roles, the individual chapters address topics ranging from pulmonary blood vessel development to vascular endothelial apoptosis, and delve deeply into our current understanding of various aspects of the pulmonary vasculature.



Reproductive Endocrinology and Infertility

Reproductive Endocrinology and Infertility Author Douglas T. Carrell
ISBN-10 1441914366
Release 2010-03-23
Pages 826
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Management of the modern reproductive endocrinology and infertility clinic has become very complex. In addition to the medical and scientific aspects, it is crucial that the modern director be aware of of incongruent fields such as marketing, accounting, management, and regulatory issues. Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice was developed to assist the practicing reproductive endocrinologist and/or laboratory director by providing an overview of relevant scientific, medical, and management issues in a single volume. Experts in all pertinent areas present concise, practical, evidence-based summaries of relevant topics, producing a key resource for physicians and scientists engaged in this exciting field of medicine. As novel technologies continue to amplify, Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice offers insight into development, and imparts extra confidence to practitioners in handling the many demands presented by their work.



Transport Across Natural and Modified Biological Membranes and its Implications in Physiology and Therapy

Transport Across Natural and Modified Biological Membranes and its Implications in Physiology and Therapy Author Julita Kulbacka
ISBN-10 9783319568959
Release 2017-10-04
Pages 140
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This book elucidates the mechanisms involved in biological membrane functions. It describes the new modalities and characterization for basic in vitro as well as computer models of biological membranes. Biological membranes are analyzed in terms of advances in molecular dynamics. The individual chapters provide an in depth analysis of images from various biological models. The potential of membrane models in the context of treatment trials is discussed. The authors present new insights and current concepts for treatment procedures (nanocarriers, electroporation, channel blockers).



A Thesaurus of English Word Roots

A Thesaurus of English Word Roots Author Horace Gerald Danner
ISBN-10 9781442233263
Release 2014-03-27
Pages 1008
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Horace G. Danner’s A Thesaurus of English Word Roots is a compendium of the most-used word roots of the English language. All word roots are listed alphabetically, along with the Greek or Latin words from which they derive, together with the roots’ original meanings. If the current meaning of an individual root differs from the original meaning, that is listed in a separate column.



Taurine 7

Taurine 7 Author Junichi Azuma
ISBN-10 9780387756813
Release 2008-11-05
Pages 546
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Taurine (2-aminoethanesulfonic acid) is an enigmatic compound abounding in animal tissues. It is present at relatively high concentrations in all electrically excitable tissues such as brain, sensory organs, heart, and muscle, and in certain endocrine glands. Some of its physiological functions are already established, for example as an essential nutrient during development and as a neuromodulator or osmolyte, but the cellular mechanisms are still mostly a matter of conjecture. Moreover, there are a number of other putative functions of taurine less well known at present. Taurine 7 contains the proceedings of the 16th International Taurine Meeting. This meeting is a multidisciplinary symposium, with participants presenting different fields of biological science. This volume focuses on all aspects of taurine research from immunology and its effect on health to chemistry and biochemistry, including future clinical applications.



Translational Anatomy and Cell Biology of Autism Spectrum Disorder

Translational Anatomy and Cell Biology of Autism Spectrum Disorder Author Michael J. Schmeisser
ISBN-10 9783319524986
Release 2017-05-25
Pages 211
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Autism spectrum disorder (ASD) affects approximately 1 % of the human population and is characterized by a core symptomatology including deficits in social interaction and repetitive patterns of behaviour plus various co-morbidities. Although a lot of progress has been made to uncover underlying causes and mechanisms throughout the last decade, we are still at the very beginning to understand this enormously complex neurodevelopmental condition. This special volume is focused on translational anatomy and cell biology of ASD. International experts from the field including several members of the EU-AIMS initiative launched by the European Union to develop novel treatments for ASD have contributed chapters on several topics covering all crucial aspects of translational ASD research with a special emphasis on ASD model systems including stem cells and animals. Primary objective is to clarify how anatomical and cell biological phenotypes of ASD will help to translate basic mechanisms to clinical practice and to efficiently treat affected individuals in the near future.



The Role of Heat Shock Proteins in Reproductive System Development and Function

The Role of Heat Shock Proteins in Reproductive System Development and Function Author Daniel J. MacPhee
ISBN-10 9783319514093
Release 2017-05-08
Pages 155
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Due to the paucity of reviews on this subject, this volume aims to be timely and promote additional basic and translational research on these proteins in reproductive system development and function within the fields of Anatomy, Embryology and Cell Biology. The breadth of the work being conducted within Reproduction is exemplified by the contributors to this series who will provide reviews on: Grp78 roles in female reproduction, small heat shock proteins/co-chaperones as players in uterine smooth muscle function, the role of heat shock proteins in sperm function and maternal contribution to oogenesis and early embryogenesis, heat shock factors and testes development, HSP90 in ovarian biology and pathology, and the role of HSP70 in regulation of autophagy in pregnancy and parturition.



Puberty

Puberty Author Philip Kumanov
ISBN-10 9783319321226
Release 2016-08-30
Pages 294
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Bringing together the latest knowledge on the growth and development of children and the most important abnormalities of puberty, this comprehensive text presents the current views on the pathogenesis, diagnostic possibilities and therapeutic options of the main deviations from the normal course of puberty (e.g., precocious and delayed puberty). The chain of physical and hormonal changes in the transitional years is carefully followed, including the regulation of the hypothalamic pulse generator as well as the timing of puberty. Further topics include growth disturbances, adolescent varicocele, adolescent gynecomastia, polycystic ovary syndrome, pubertal acne, and the psychosocial development of adolescents with pubertal abnormalities. Written and edited by internationally noted experts, Puberty will be an excellent resource for pediatricians, endocrinologists, gynecologists, andrologists, urologists, family practitioners, child psychologists and public health specialists – all those who will be challenged in their everyday practice with the problems of puberty.



Color Atlas of Cytology Histology and Microscopic Anatomy

Color Atlas of Cytology  Histology  and Microscopic Anatomy Author Wolfgang Kühnel
ISBN-10 1588901750
Release 2003
Pages 534
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This timeless pocket atlas is the ideal visual companion to histology and cytology textbooks. First published in 1950 and translated into eight languages, Kuehnel's Pocket Atlas of Cytology, Histology and Microscopic Anatomy is a proven classic. The fully revised and updated fourth edition contains 745 full-color illustrations - almost 200 more than were included in the third edition. Superb, high-quality microphotographs and pathologic stains are accompanied by legends, informative texts, and numerous cross-references. Key features of the updated fourth edition: More than 700 high-quality illustrations using advanced techniques in histology and electron microscopy Practical, information Concise and focused text Key concepts and ideas illustrated in less than 550 pages Ideal for exam preparation, this world-class book is an indispensable visual study tool for medical, dental and biology students. It can also serve as an outstanding review and refresher text.



Science Terms Made Easy

Science Terms Made Easy Author Joseph S. Elias
ISBN-10 0313338965
Release 2007
Pages 218
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Defines scientific words, gives the language that they originally came from, and describes what each word--and various parts of that word--meant in that original language, with appendices that define common prefixes, roots, and suffixes.