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Statistical Models in Epidemiology the Environment and Clinical Trials

Statistical Models in Epidemiology  the Environment  and Clinical Trials Author M.Elizabeth Halloran
ISBN-10 9781461212843
Release 2012-12-06
Pages 283
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This IMA Volume in Mathematics and its Applications STATISTICAL MODELS IN EPIDEMIOLOGY, THE ENVIRONMENT,AND CLINICAL TRIALS is a combined proceedings on "Design and Analysis of Clinical Trials" and "Statistics and Epidemiology: Environment and Health. " This volume is the third series based on the proceedings of a very successful 1997 IMA Summer Program on "Statistics in the Health Sciences. " I would like to thank the organizers: M. Elizabeth Halloran of Emory University (Biostatistics) and Donald A. Berry of Duke University (Insti tute of Statistics and Decision Sciences and Cancer Center Biostatistics) for their excellent work as organizers of the meeting and for editing the proceedings. I am grateful to Seymour Geisser of University of Minnesota (Statistics), Patricia Grambsch, University of Minnesota (Biostatistics); Joel Greenhouse, Carnegie Mellon University (Statistics); Nicholas Lange, Harvard Medical School (Brain Imaging Center, McLean Hospital); Barry Margolin, University of North Carolina-Chapel Hill (Biostatistics); Sandy Weisberg, University of Minnesota (Statistics); Scott Zeger, Johns Hop kins University (Biostatistics); and Marvin Zelen, Harvard School of Public Health (Biostatistics) for organizing the six weeks summer program. I also take this opportunity to thank the National Science Foundation (NSF) and the Army Research Office (ARO), whose financial support made the workshop possible. Willard Miller, Jr.



Amstat News

Amstat News Author
ISBN-10 UOM:39015049351615
Release 1999
Pages
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Amstat News has been writing in one form or another for most of life. You can find so many inspiration from Amstat News also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Amstat News book for free.



The Mathematical Sciences in 2025

The Mathematical Sciences in 2025 Author Committee on the Mathematical Sciences in 2025
ISBN-10 9780309284578
Release 2013-05-13
Pages 205
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The mathematical sciences are part of nearly all aspects of everyday life--the discipline has underpinned such beneficial modern capabilities as Internet search, medical imaging, computer animation, numerical weather predictions, and all types of digital communications. The Mathematical Sciences in 2025 examines the current state of the mathematical sciences and explores the changes needed for the discipline to be in a strong position and able to maximize its contribution to the nation in 2025. It finds the vitality of the discipline excellent and that it contributes in expanding ways to most areas of science and engineering, as well as to the nation as a whole, and recommends that training for future generations of mathematical scientists should be re-assessed in light of the increasingly cross-disciplinary nature of the mathematical sciences. In addition, because of the valuable interplay between ideas and people from all parts of the mathematical sciences, the report emphasizes that universities and the government need to continue to invest in the full spectrum of the mathematical sciences in order for the whole enterprise to continue to flourish long-term.



Viral Infections of Humans

Viral Infections of Humans Author Richard A. Kaslow
ISBN-10 9781489974488
Release 2014-09-27
Pages 1215
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Striking changes have occurred in the world since the publication of the last edition of Viral Infections of Humans. The global population is rapidly approaching 8 billion; climate change is leading to the introduction of new hosts, vectors and virus diseases heretofore never seen in many parts of the world; technological advances have revolutionized the ability to recognize and characterize viruses new and old; vaccines are altering the epidemiological landscape of the diseases they target, in some cases raising the hope of their eradication and remarkably powerful computational tools are enabling not only detection of outbreaks of disease much sooner than in the past but also, through complex mathematical modeling, more accurate prediction of their potential impact. The new Fifth Edition of Viral Infections of Humans captures the both the excitement and frustration of the dynamic struggle between humankind and the viruses that continue to cause immense suffering. It presents the latest concepts, methods and technologies in epidemiology, detection, investigation, modeling and intervention. Updated and entirely new chapters by dozens of experts across the field provide analytic summaries of current knowledge of viruses and prions causing acute syndromes, chronic illnesses and/or malignancies. In sum, this ambitiously expanded volume offers a uniquely comprehensive perspective on viruses in humans, from agents of classic diseases (e.g., hepatitis, measles, polio, rabies and yellow fever), to those with greatest pandemic impact (e.g., influenza and human immunodeficiency virus), to those discovered relatively recently (e.g., henipavirus, metapneumovirus and norovirus). The new Fifth Edition of Viral Infections of Humans is an invaluable reference for students, fellows and established professionals in the fields of microbiology, public health and infectious disease epidemiology, medicine and health policy.



Facilitating Interdisciplinary Research

Facilitating Interdisciplinary Research Author Institute of Medicine
ISBN-10 0309165482
Release 2005-04-04
Pages 332
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Facilitating Interdisciplinary Research examines current interdisciplinary research efforts and recommends ways to stimulate and support such research. Advances in science and engineering increasingly require the collaboration of scholars from various fields. This shift is driven by the need to address complex problems that cut across traditional disciplines, and the capacity of new technologies to both transform existing disciplines and generate new ones. At the same time, however, interdisciplinary research can be impeded by policies on hiring, promotion, tenure, proposal review, and resource allocation that favor traditional disciplines. This report identifies steps that researchers, teachers, students, institutions, funding organizations, and disciplinary societies can take to more effectively conduct, facilitate, and evaluate interdisciplinary research programs and projects. Throughout the report key concepts are illustrated with case studies and results of the committee’s surveys of individual researchers and university provosts.



Clinical Research Informatics

Clinical Research Informatics Author Rachel Richesson
ISBN-10 9781848824485
Release 2012-02-10
Pages 419
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The purpose of the book is to provide an overview of clinical research (types), activities, and areas where informatics and IT could fit into various activities and business practices. This book will introduce and apply informatics concepts only as they have particular relevance to clinical research settings.



Epidemiology and Biostatistics

Epidemiology and Biostatistics Author Bryan Kestenbaum
ISBN-10 0387884335
Release 2009-08-28
Pages 242
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Concise, fast-paced, intensive introduction to clinical research design for students and clinical research professionals Readers will gain sufficient knowledge to pass the United States Medical Licensing Examination part I section in Epidemiology



Mathematical Epidemiology

Mathematical Epidemiology Author Fred Brauer
ISBN-10 9783540789109
Release 2008-04-30
Pages 414
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Based on lecture notes of two summer schools with a mixed audience from mathematical sciences, epidemiology and public health, this volume offers a comprehensive introduction to basic ideas and techniques in modeling infectious diseases, for the comparison of strategies to plan for an anticipated epidemic or pandemic, and to deal with a disease outbreak in real time. It covers detailed case studies for diseases including pandemic influenza, West Nile virus, and childhood diseases. Models for other diseases including Severe Acute Respiratory Syndrome, fox rabies, and sexually transmitted infections are included as applications. Its chapters are coherent and complementary independent units. In order to accustom students to look at the current literature and to experience different perspectives, no attempt has been made to achieve united writing style or unified notation. Notes on some mathematical background (calculus, matrix algebra, differential equations, and probability) have been prepared and may be downloaded at the web site of the Centre for Disease Modeling (www.cdm.yorku.ca).



Statistical Models in Epidemiology

Statistical Models in Epidemiology Author David Clayton
ISBN-10 9780199671182
Release 2013-01-17
Pages 384
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This self-contained account of the statistical basis of epidemiology has been written for those with a basic training in biology. No previous knowledge of the subject is assumed and mathematics is deliberately kept at a manageable level. Based on a highly successful course, this book explains the essential statistics for all epidemiologists.



Mathematical Modeling in Experimental Nutrition

Mathematical Modeling in Experimental Nutrition Author Andrew J. Clifford
ISBN-10 0306460203
Release 1998-08-31
Pages 426
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Nutrients have been recognized as essential for maximum growth, successful reproduction, and infection prevention since the 1940s; since that time, the lion's share of nutrient research has focused on defining their role in these processes. Around 1990, however, a major shift began in the way that researchers viewed some nutrients particularly the vitamins. This shift was motivated by the discovery that modest declines in vitamin nutritional status are associated with an increased risk of ill-health and disease (such as neural tube defects, heart disease, and cancer), especially in those populations or individuals who are genetically predisposed. In an effort to expand upon this new understanding of nutrient action, nutritionists are increasingly turning their focus to the mathematical modeling of nutrient kinetic data. The availability of suitably-tagged (isotope) nutrients (such as B-carotene, vitamin A, folate, among others), sensitive analytical methods to trace them in humans (mass spectrometry and accelerator mass spectrometry), and powerful software (capable of solving and manipulating differential equations efficiently and accurately), has allowed researchers to construct mathematical models aimed at characterizing the dynamic and kinetic behavior of key nutrients in vivo in humans at an unparalleled level of detail.



Value Creation in the Pharmaceutical Industry

Value Creation in the Pharmaceutical Industry Author Alexander Schuhmacher
ISBN-10 9783527339136
Release 2016-04-11
Pages 508
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This practical guide for advanced students and decision-makers in the pharma and biotech industry presents key success factors in R&D along with value creators in pharmaceutical innovation. A team of editors and authors with extensive experience in academia and industry and at some of the most prestigious business schools in Europe discusses in detail the innovation process in pharma as well as common and new research and innovation strategies. In doing so, they cover collaboration and partnerships, open innovation, biopharmaceuticals, translational medicine, good manufacturing practice, regulatory affairs, and portfolio management. Each chapter covers controversial aspects of recent developments in the pharmaceutical industry, with the aim of stimulating productive debates on the most effective and efficient innovation processes. A must-have for young professionals and MBA students preparing to enter R&D in pharma or biotech as well as for students on a combined BA/biomedical and natural sciences program.



Statistical Models for Data Analysis

Statistical Models for Data Analysis Author Paolo Giudici
ISBN-10 9783319000329
Release 2013-07-01
Pages 419
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The papers in this book cover issues related to the development of novel statistical models for the analysis of data. They offer solutions for relevant problems in statistical data analysis and contain the explicit derivation of the proposed models as well as their implementation. The book assembles the selected and refereed proceedings of the biannual conference of the Italian Classification and Data Analysis Group (CLADAG), a section of the Italian Statistical Society. ​



The Taming of Chance

The Taming of Chance Author Ian Hacking
ISBN-10 0521388848
Release 1990-08-31
Pages 264
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This book combines detailed scientific historical research with characteristic philosophic breadth and verve.



Bioterrorism

Bioterrorism Author H. T. Banks
ISBN-10 9780898715491
Release 2003-01-01
Pages 240
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Collects the detailed contributions of selected groups of experts from the fields of biostatistics, control theory, epidemiology, and mathematical biology who have engaged in the development of frameworks, models, and mathematical methods needed to address some of the pressing challenges posed by acts of terror.



Drug Benefits and Risks

Drug Benefits and Risks Author C.J. van Boxtel
ISBN-10 9781607503453
Release 2008-08-06
Pages 848
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This updated and revised 2nd edition of Drug Benefits and Risks is an inclusive reference exploring the scientific basis and practice of drug therapy. The key concept is to look at the balance between the benefits and risks of drugs, but in this context also highlighting the social impact which drugs have in modern societies. Taking an evidence-based approach to the problem, the practice of clinical pharmacology and pharmacotherapy in the developing as well as the developed world is examined. For this purpose the book covers general clinical pharmacology, pharmacology of various drug groups and the treatments specific to various diseases; the book gives guidance on how doctors should act so that drugs can be used effectively and safely; and it encourages the rational use of drugs in society. This publication brings together a large amount of excellent content that will be invaluable for anyone working within, or associated with, the field of clinical pharmacology and pharmacotherapy - undergraduates, postgraduates, regulatory authorities and the pharmaceutical industry.



Fungal Diseases

Fungal Diseases Author Forum on Microbial Threats
ISBN-10 9780309212267
Release 2011-09-08
Pages 488
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Fungal diseases have contributed to death and disability in humans, triggered global wildlife extinctions and population declines, devastated agricultural crops, and altered forest ecosystem dynamics. Despite the extensive influence of fungi on health and economic well-being, the threats posed by emerging fungal pathogens to life on Earth are often underappreciated and poorly understood. On December 14 and 15, 2010, the IOM's Forum on Microbial Threats hosted a public workshop to explore the scientific and policy dimensions associated with the causes and consequences of emerging fungal diseases.



Biomarker Validation

Biomarker Validation Author Harald Seitz
ISBN-10 9783527337194
Release 2015-06-02
Pages 264
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Built on a decade of experience with novel molecular diagnostics, this practice-oriented guide shows how to cope with validation issues during all stages of biomarker development, from the first clinical studies to the eventual commercialization of a new diagnostic test.