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The Living Clock

The Living Clock Author John D. Palmer
ISBN-10 9780190286644
Release 2002-03-14
Pages 176
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From one-celled paramecium to giant blue whales, we all have internal clocks that regulate the rhythms we live by. In The Living Clock, John Palmer, one of the world's leading authorities on these rhythms, takes us on a tour of this broad and multifaceted subject, examining everything from glowing fruit flies to the best cures for jet lag. Palmer has a wonderful sense of humor and an eye for the startling fact. We learn that fiddler crabs--in a lab where there are no time nor tide cues--remain active when low tide would occur and motionless during high tide, the same pattern they follow in their natural habitat. (In fact, you can remove a crab's leg and the leg will keep a tidal rhythm as long as it's kept alive.) Moreover, humans are subject to more than one hundred biological rhythms. Mental acuity peaks in the afternoon, for instance, and our blood pressure peaks at seven in the morning (when most heart attacks occur). The time of day you take medication can affect how well it works. And Palmer shows that when our clocks are thrown off kilter, trouble follows, especially for rotating shift workers--the Bhopal spill, the Chernobyl reactor explosion, and the Three Mile Island accident all happened when new crews began early-hour shifts. No one has discovered exactly how our internal clocks work--Palmer says a Nobel Prize awaits that lucky scientist--but they are no less fascinating for their inexplicable nature. Frequently amusing and always eye-opening, The Living Clock is a treat for everyone curious about the nature of life as well as anyone planning a long jet flight.

Circadian Physiology Third Edition

Circadian Physiology  Third Edition Author Roberto Refinetti, PhD.
ISBN-10 9781466514980
Release 2016-04-21
Pages 727
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Circadian rhythms influence most of our life activities, notably getting up and going to sleep every day. This new edition of Circadian Physiology delves into the mechanisms surrounding how these rhythms work, the physiology and biology behind them, and the latest research on this cutting-edge field. The book also discusses a wide variety of practical topics including the prevention of jet lag, management of shift work, sleep disorders, depression, and the optimal times for physical and intellectual activities. To facilitate its use as a textbook, the book contains summaries, suggestions for further reading, links to pertinent websites, and exercises at the end of each chapter. It also includes software for data analysis, tutorials, and simulation programs discussed throughout the text. In addition, more than a thousand references have been added, resulting in a total of more than 6000 references. The text has been thoroughly updated as a result of major advances in recent years. This edition adds discussion on the anatomical and physiological characterization of photoresponsive ganglionic cells in the mammalian retina, molecular circadian clocks in cells of multiple organs other than the hypothalamus and the pineal gland, and advances in the understanding of post-translational mechanisms in the operation of the molecular clock.

Nature Alive

Nature Alive Author Adam Scarfe
ISBN-10 9781527509689
Release 2018-04-18
Pages 326
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This volume pays homage to Alfred North Whitehead’s (1861-1947) profound lecture and essay entitled “Nature Alive,” which was one of his most mature expressions of his process-relational metaphysics – a holistic conceptual framework that renders vivid the dynamic character of the natural world and the intrinsic purposiveness, selective agency, and creativity of living organisms. Inspired by, but not beholden to, Whitehead’s process metaphysical “lens,” the contributors to this volume bring a multiplicity of philosophical orientations to the table in challenging the mechanistic and reductionistic neo-Darwinian paradigm that is still dominant today in the life sciences. Mechanistic neo-Darwinism views nature and living organisms as “machines,” namely, as networks of externally related and linear causal “switches,” “dials,” “levers,” “pulleys,” and “gears,” that are “at the ready” for technological and biotechnological manipulation. Seeking a conceptual framework and a language that are more adequate to the study of the natural world and of living creatures than the mechanistic orientation, the contributors to this volume explore several of the “New Frontiers of Biology,” which are areas of biology whose findings to some extent go beyond the explanatory confines of the Modern Synthesis of natural selection and genetics. Most notably, emergence theory, the theory of organic selection, epigenetics, homeostasis, chronobiology, and autopoiesis research can provide us with key insights that can assist us in explaining how living agents emerged, including the evolutionary origins of mentality, consciousness, and mind. Moreover, attention to the “New Frontiers of Biology” can serve to “re-enchant” our understanding of the natural world and to prevent ecological devastation, through a restoration to objectivity of notions such as “intrinsic purposiveness,” “selective agency,” “creativity,” and “intrinsic value.”

The Geometry of Biological Time

The Geometry of Biological Time Author Arthur T. Winfree
ISBN-10 9781475734843
Release 2013-03-09
Pages 779
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Dealing with dynamics of processes that repeat themselves regularly, this revised and updated edition extends the thread from 1980 to the present day, concentrating on areas of interest where there will be much activity in the future. This involves going through spatial biochemical, electrophysiological, and organismic dynamical systems and patterns that were discovered by pursuing the theme of phase singularities introduced in the original book. In particular the work on excitability in cell membranes will be thoroughly updated as will the references throughout the book.


Insomnia Author Eluned Summers-Bremner
ISBN-10 9781861895646
Release 2008-02-27
Pages 224
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This cultural, historical, and scientific exploration of sleeplessness by Eluned Summers-Bremner begins with the literature of ancient times, and finds its sufferers in prominent texts such as the Iliad, the Odyssey, the Mesopotamian epic Gilgamesh, and the Bible. Moving to Romantic and Gothic literature, she shows how sleeplessness continued to play a large role as the advent of street lighting in the nineteenth century inspired the fantastical blurring of daytime reality and night visions and authors connected insomnia to the ephemeral worlds of nightmares and the sublime. Meanwhile, throughout the ages insomnia has been variously categorized by the medical community as a manifestation of a deeper psychological or physical malady. Today’s medical solutions tend to involve prescription drugs—but, as Insomnia reveals, important questions linger about the role of the pharmaceutical industry and the effectiveness of such treatments. “Summers-Bremner’s account of literary usages of insomnia, from Gilgamesh to Garcia Márquez, is a rich one, sufficient to make the case that insomnia is a recurrent theme in Western culture.”––Wall Street Journal “A whimsical tour of the history of how different cultures have viewed not only insomnia but also the night itself, sleep, dreams, darkness, and activities that occur in the dark.”—New England Journal of Medicine “Summers-Bremner’s excellent account of insomnia shows that the consideration of our waking moments is indicative of the changing ways we think about life.”—Financial Times Magazine

Galileo s pendulum

Galileo s pendulum Author Roger G. Newton
ISBN-10 PSU:000057182643
Release 2004
Pages 153
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Explains the history of newly evolving mechanisms based on the pendulum's swing and the sciences underlying their function, covering a range of topics from the invention of time zones and biorhythms to musical harmony and quantum electrodynamics.

An Introduction to Biological Rhythms

An Introduction to Biological Rhythms Author John Palmer
ISBN-10 9780323152426
Release 2012-12-02
Pages 394
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An Introduction to Biological Rhythms provides an introduction to the subject of biological rhythms. The opening chapters present an overview of biological rhythms, their properties, and clock control, followed by a survey of rhythms in plants and animals. The subsequent chapters cover tidal rhythms and human rhythms; sun-compass, star-compass, and moon compass orientation of animals; the clock control of plant and animal photoperiodism; evidence for external timing of biological clocks; and models and mechanisms for endogenous timekeeping. The book also includes biographical sketches of Dr. Frank A. Brown, Jr., Morrison Professor of Biology at Northwestern University; and Dr. Leland N. Edmunds, Jr., Professor and Head of the Division of Biological Sciences at the Stony Brook campus of the State University of New York. This book is meant for the inquiring student seeking an introduction to the subject and for busy biologists in other fields who want to get a ""feel"" for the subject. It can also serve as a basic textbook for the existing biorhythms courses and act as a seed for the inauguration of new courses.

The Rhythms Of Life

The Rhythms Of Life Author Leon Kreitzman
ISBN-10 9781847653727
Release 2011-09-30
Pages 469
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Popular science at its most exciting: the breaking new world of chronobiology - understanding the rhythm of life in humans and all plants and animals. The entire natural world is full of rhythms. The early bird catches the worm -and migrates to an internal calendar. Dormice hibernate away the winter. Plants open and close their flowers at the same hour each day. Bees search out nectar-rich flowers day after day. There are cicadas that can breed for only two weeks every 17 years. And in humans: why are people who work anti-social shifts more illness prone and die younger? What is jet-lag and can anything help? Why do teenagers refuse to get up in the morning, and are the rest of us really 'larks' or 'owls'? Why are most people born (and die) between 3am-5am? And should patients be given medicines (and operations) at set times of day, because the body reacts so differently in the morning, evening and at night? The answers lie in our biological clocks the mechanisms which give order to all living things. They impose a structure that enables us to change our behaviour in relation to the time of day, month or year. They are reset at sunrise and sunset each day to link astronomical time with an organism's internal time.

Applied Memory

Applied Memory Author Matthew Kelley
ISBN-10 STANFORD:36105132280186
Release 2009
Pages 355
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The goal of the applied memory volume is to highlight many interesting and creative applications of basic memory phenomena that are underrepresented, or even unrepresented, in the literature. Authors were charged with the task of reviewing relevant basic and applied research and offering new empirical investigations into the applications of these benchmark phenomena. To this end, Applied Memory, consists of 17 chapters that explore the influences of generation, irrelevant speech, verbal overshadowing, isolation, part-set cuing, reminiscence, hyperemnesia, placebos, mental state, metamemory knowledge, flashbulb events, and traumatic events on memory in everyday settings, as well as applications of source memory, social memory, involuntary autobiographical memory, dream memory, and strategic memory regulation. The volume is designed as a resource for basic and applied memory researchers and as a supplementary text in graduate or upper-level undergraduate courses in cognitive psychology, human memory, or applied psychology.

The Writers Directory

The Writers Directory Author Miranda H. Ferrara
ISBN-10 UOM:39015054036648
Release 2003
Pages 999
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The Writers Directory has been writing in one form or another for most of life. You can find so many inspiration from The Writers Directory also informative, and entertaining. Click DOWNLOAD or Read Online button to get full The Writers Directory book for free.

The Writers directory 2005

The Writers directory 2005 Author Miranda H. Ferrara
ISBN-10 1558625283
Release 2004
Pages 2164
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The Writers directory 2005 has been writing in one form or another for most of life. You can find so many inspiration from The Writers directory 2005 also informative, and entertaining. Click DOWNLOAD or Read Online button to get full The Writers directory 2005 book for free.

Writers Directory 2010 V1 A L

Writers Directory 2010 V1 A L Author
ISBN-10 155862600X
Release 2009-05-01
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Features bibliographical, biographical and contact information for living authors worldwide who have at least one English publication. Entries include name, pseudonyms, addresses, citizenship, birth date, specialization, career information and a bibliography.

Biological Clock in Fish

Biological Clock in Fish Author Ewa Kulczykowska
ISBN-10 9781439845110
Release 2010-05-27
Pages 280
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Each organism has its own internal biological clock, which is reset by environmental cues (Zeitgebers), thus keeping it synchronized with the external environment. It is a chemically based oscillating system within cells, relying on molecular feedback loops. Circadian biological clocks exist in most organisms. What is so special about the clock in fish? Where is it located—in the retina, inside the brain, or in the pineal? What is the molecular basis of its function? How is the clock able to keep time in the absence of environmental cues? Although biological clocks have been intensively studied over the past four decades, only recently have the tools needed to examine the molecular basis of circadian rhythms become available. This book reviews the state of knowledge in sufficient detail and presents the latest contributions to the field, showing fish provide a unique model of the circadian biological clock.

Encyclopedia of Behavioral Neuroscience

Encyclopedia of Behavioral Neuroscience Author
ISBN-10 9780080453965
Release 2010-06-03
Pages 1816
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Behavioral Neuroscientists study the behavior of animals and humans and the neurobiological and physiological processes that control it. Behavior is the ultimate function of the nervous system, and the study of it is very multidisciplinary. Disorders of behavior in humans touch millions of people’s lives significantly, and it is of paramount importance to understand pathological conditions such as addictions, anxiety, depression, schizophrenia, autism among others, in order to be able to develop new treatment possibilities. Encyclopedia of Behavioral Neuroscience is the first and only multi-volume reference to comprehensively cover the foundation knowledge in the field. This three volume work is edited by world renowned behavioral neuroscientists George F. Koob, The Scripps Research Institute, Michel Le Moal, Université Bordeaux, and Richard F. Thompson, University of Southern California and written by a premier selection of the leading scientists in their respective fields. Each section is edited by a specialist in the relevant area. The important research in all areas of Behavioral Neuroscience is covered in a total of 210 chapters on topics ranging from neuroethology and learning and memory, to behavioral disorders and psychiatric diseases. The only comprehensive Encyclopedia of Behavioral Neuroscience on the market Addresses all recent advances in the field Written and edited by an international group of leading researchers, truly representative of the behavioral neuroscience community Includes many entries on the advances in our knowledge of the neurobiological basis of complex behavioral, psychiatric, and neurological disorders Richly illustrated in full color Extensively cross referenced to serve as the go-to reference for students and researchers alike The online version features full searching, navigation, and linking functionality An essential resource for libraries serving neuroscientists, psychologists, neuropharmacologists, and psychiatrists


Choice Author
ISBN-10 UCSC:32106016978238
Release 2002
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Choice has been writing in one form or another for most of life. You can find so many inspiration from Choice also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Choice book for free.

The Key reporter

The Key reporter Author
ISBN-10 IND:30000107681300
Release 2001
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The Key reporter has been writing in one form or another for most of life. You can find so many inspiration from The Key reporter also informative, and entertaining. Click DOWNLOAD or Read Online button to get full The Key reporter book for free.

Therapeutic Implications of Circadian Rhythms

Therapeutic Implications of Circadian Rhythms Author Guangrui Yang
ISBN-10 9782889196654
Release 2015-10-12
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Circadian rhythms are biological processes displaying endogenous and entrainable oscillations of about 24 hours. They are driven by a group of genes called clock genes that have been widely observed in plants, animals and even in bacteria. In mammals, the core clock genes are rhythmically expressed in both the suprachiasmatic nucleus (SCN), the master clock residing in the hypothalamus, and almost all peripheral tissues where they control numerous target genes in a circadian manner, and thus affect many physiological and biochemical processes. Evidence suggests that disruption of the circadian rhythms (or desynchronization) is a significant risk factor for the development of metabolic diseases, cardiovascular diseases, cancer and sleep disorders. Evidence also suggests that the disruption suppresses immune function and increases vulnerability to infectious diseases. Restoring or strengthening the circadian rhythm may be therapeutic for these conditions. This becomes exceptionally important in modern societies because many people are suffering from frequent desynchronization due to shift working, exposure to artificial light, travel by transmeridian air flight, and involvement in social activities. Besides, the temporal variations in the incidence and severity of many diseases, such as the onset of cardiovascular events, chronic obstructive pulmonary disease (COPD), inflammatory diseases and mental disorders have also drawn increasing attention to the circadian clock. The circadian rhythms affect not only the health status, but also the drug efficiency. The effects (and side effects) of many drugs vary with biological timing. The tolerance of many medications displays circadian variation as well. The timing of medical treatment in coordination with the body clock may significantly increase the desired effects of drugs, and lower the dose and toxicity. In addition, circadian rhythms can also be modulated by some therapeutic drugs, for example, melatonin and modafinil, which are used to treat circadian rhythm sleep disorders. In this Research Topic, we assemble a series of critical review and research articles that focus on the therapeutic implications of circadian rhythms. Topics include, but are not limited to: • Circadian disruption caused diseases or disorders and related intervention • Temporal manifestation of diseases or disorders and therapeutic implications • The effects of circadian rhythms on drugs • The effects of drugs on circadian rhythms