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Viruses

Viruses Author David R. Harper
ISBN-10 9781136665424
Release 2011-06-20
Pages 346
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Viruses: Biology, Application, and Control is a concise textbook for advanced undergraduate and graduate students covering the essential aspects of virology included in biomedical science courses. It is an updated and expanded version of David Harpers Molecular Virology, Second Edition. Focusing on key mechanisms and developments, Viruses presents many new sections that cover recent advances including virus evolution, emerging infections, virus extinction, control of infections, antiviral drugs, gene therapy, bacteriophage therapy, and diagnostics. The first chapters introduce the reader to the structure and nature of viruses, including their classification and evolution. As viruses cause widespread and serious disease, the ensuing chapters explain how they interact with the immune system and the different ways we try to defeat them: vaccines, antiviral drugs, and immunotherapy. There is also coverage of laboratory methods for viral detection and laboratory diagnosis. While viruses do cause disease, many do not, and their special biology means they can have beneficial uses. This aspect of viruses is not neglected. Finally, one of the most interesting areas in virology, and one given extensive coverage here, is how new viruses emerge and establish themselves. Viruses: Biology, Application, and Control is a rigorous treatment of the molecular side of virology and its conceptual approach makes it an essential text for students and non-specialists.



Viruses

Viruses Author Paula Tennant
ISBN-10 9780128111949
Release 2018-03-12
Pages 392
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Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology provides an up-to-date introduction to human, animal and plant viruses within the context of recent advances in high-throughput sequencing that have demonstrated that viruses are vastly greater and more diverse than previously recognized. It covers discoveries such as the Mimivirus and its virophage which have stimulated new discussions on the definition of viruses, their place in the current view, and their inherent and derived ‘interactomics’ as defined by the molecules and the processes by which virus gene products interact with themselves and their host’s cellular gene products. Further, the book includes perspectives on basic aspects of virology, including the structure of viruses, the organization of their genomes, and basic strategies in replication and expression, emphasizing the diversity and versatility of viruses, how they cause disease and how their hosts react to such disease, and exploring developments in the field of host-microbe interactions in recent years. The book is likely to appeal, and be useful, to a wide audience that includes students, academics and researchers studying the molecular biology and applications of viruses Provides key insights into recent technological advances, including high-throughput sequencing Presents viruses not only as formidable foes, but also as entities that can be beneficial to their hosts and humankind that are helping to shape the tree of life Features exposition on the diversity and versatility of viruses, how they cause disease, and an exploration of virus-host interactions



Harnessing the Power of Viruses

Harnessing the Power of Viruses Author Boriana Marintcheva
ISBN-10 9780128105153
Release 2017-11-13
Pages 296
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Harnessing the Power of Viruses explores the application of scientific knowledge about viruses and their lives to solve practical challenges and further advance molecular sciences, medicine and agriculture. The book contains virus-based tools and approaches in the fields of: i) DNA manipulations in vitro and in vivo; ii) Protein expression and characterization; and iii) Virus- Host interactions as a platform for therapy and biocontrol are discussed. It steers away from traditional views of viruses and technology, focusing instead on viral molecules and molecular processes that enable science to better understand life and offer means for addressing complex biological phenomena that positively influence everyday life. The book is written at an intermediate level and is accessible to novices who are willing to acquire a basic level of understanding of key principles in molecular biology, but is also ideal for advanced readers interested in expanding their biological knowledge to include practical applications of molecular tools derived from viruses. Explores virus-based tools and approaches in DNA manipulation, protein expression and characterization and virus-host interactions Provides a dedicated focus on viral molecules and molecular processes that enable science to better understand life and address complex biological phenomena Includes an overview of modern technologies in biology that were developed using viral components/elements and knowledge about viral processes



Grapevine Viruses Molecular Biology Diagnostics and Management

Grapevine Viruses  Molecular Biology  Diagnostics and Management Author Baozhong Meng
ISBN-10 9783319577067
Release 2017-08-03
Pages 698
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The domestication of grapes dates back five thousand years ago and has spread to nearly all continents. In recent years, grape acreage has increased dramatically in new regions, including the United States of America, Chile, Asia (China and India), and Turkey. A major limiting factor to the sustained production of premium grapes and wines is infections by viruses. The advent of powerful molecular and metagenomics technologies, such as molecular cloning and next generation sequencing, allowed the discovery of new viruses from grapes. To date, grapevine is susceptible to 64 viruses that belong to highly diverse taxonomic groups. The most damaging diseases include: (1) infectious degeneration; (2) leafroll disease complex; and (3) rugose wood complex. Recently, two new disease syndromes have been recognized: Syrah decline and red blotch. Losses due to fanleaf degeneration are estimated at $1 billion annually in France alone. Other diseases including leafroll, rugose wood, Syrah decline and red blotch can result in total crop loss several years post-infection. This situation is further exacerbated by mixed infections with multiple viruses and other biotic as well as adverse abiotic environmental conditions, such as drought and winter damage, causing even greater destruction. The book builds upon the last handbook (written over twenty years ago) on the part of diagnostics and extensively expands its scope by inclusion of molecular biology aspects of select viruses that are widespread and economically most important. This includes most current information on the biology, transmission, genome replication, transcription, subcellular localization, as well as virus-host interactions. It also touches on several novel areas of scientific inquiry. It also contains suggested directions for future research in the field of grapevine virology.



Viroids and Satellites

Viroids and Satellites Author Ahmed Hadidi
ISBN-10 9780128017029
Release 2017-07-18
Pages 746
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Viroids and Satellites describes plant diseases and their causal agents while also addressing the economic impact of these diseases. The book discusses various strategies for state-of-the-art methods for the detection and control of pathogens in their infected hosts and provides pivotal information from the discovery of viroids through the analysis of their molecular and biological properties, to viroid pathogenesis, host interactions, and RNA silencing pathways. Students, researchers and regulators will find this to be a comprehensive resource on the topics presented. Provides coverage of the basic biological properties of disease, along with applied knowledge Features economic impacts, transmission, geographical distribution, epidemiology, detection, and control within each chapter Organizes viroid diseases by viroid taxonomy and viroid species



Understanding Viruses

Understanding Viruses Author Teri Shors
ISBN-10 9781284025927
Release 2016-08-02
Pages 944
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The Third Edition of best-selling Understanding Viruses provides a strong, comprehensive introduction to human viral diseases. It provides a balanced approach to virology, combining the molecular, clinical, and historical aspects, making it the ideal text for undergraduate students majoring in biology, microbiology, medical technology, or pre-med.



Fish Diseases

Fish Diseases Author Galina Jeney
ISBN-10 9780128045855
Release 2017-02-11
Pages 278
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Fish Diseases: Prevention and Control Strategies provides essential information on disease prevention and treatment by the most experienced fish culturists in the industry. The book presents both traditional and novel methodologies of identifying and addressing fish disease risk, along with preventative and responsive insights to the challenges impacting fish production today. Both specific (vaccination) and non-specific (immunostimulation) approaches are explored, from maintaining optimal environmental conditions, to understanding how stressors in fish affect their immune system. Includes relevant information on government restrictions on drug usage in aquaculture to address the strict demand for fish products free of pollutants/antibiotics Presents best practices in fish farming to prevent disease and promote good health status and fish disease management Provides the most recent research on fish diseases prevention, the pathogens most studied, and options for methods of treatment



Molecular Virology of Human Pathogenic Viruses

Molecular Virology of Human Pathogenic Viruses Author Wang-Shick Ryu
ISBN-10 9780128009994
Release 2016-03-30
Pages 440
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Molecular Virology of Human Pathogenic Viruses presents robust coverage of the key principles of molecular virology while emphasizing virus family structure and providing key context points for topical advances in the field. The book is organized in a logical manner to aid in student discoverability and comprehension and is based on the author’s more than 20 years of teaching experience. Each chapter will describe the viral life cycle covering the order of classification, virion and genome structure, viral proteins, life cycle, and the effect on host and an emphasis on virus-host interaction is conveyed throughout the text. Molecular Virology of Human Pathogenic Viruses provides essential information for students and professionals in virology, molecular biology, microbiology, infectious disease, and immunology and contains outstanding features such as study questions and recommended journal articles with perspectives at the end of each chapter to assist students with scientific inquiries and in reading primary literature. Presents viruses within their family structure Contains recommended journal articles with perspectives to put primary literature in context Includes integrated recommended reading references within each chapter Provides access to online ancillary package inclusive of annotated PowerPoint images, instructor’s manual, study guide, and test bank



Synthetic Biology

Synthetic Biology Author Huimin Zhao
ISBN-10 9780123978202
Release 2013-03-21
Pages 352
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Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystems. Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomes Highlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development.



Parasitoid Viruses

Parasitoid Viruses Author Nancy E. Beckage
ISBN-10 9780123848598
Release 2011-09-14
Pages 312
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Parasitoids are parasitic insects that kill their insect hosts in immature pre-reproductive stages. Parasitoids are employed in biological control programs worldwide to kill insect pests and are environmentally safe and benign alternatives to chemical pesticides. As resistance to chemical pesticides continues to escalate in many pest populations, attention is now refocusing on biologically-based strategies to control pest species in agriculture and forestry as well as insect vector populations that transmit human and animal diseases. Parasitoids are an economically critical element in this equation and ‘integrated pest management.’ Viruses have evolved intimate associations with parasitoids, and this book features sections on both symbiotic viruses that are integrated into the wasp’s chromosomal DNA (polydnaviruses) that play critical roles in suppressing host immunity during parasitism. A separate section with additional chapters on viral pathogens that infect parasitoids to cause disease and act as detrimental agents that limit effectiveness of wasp species employed in biological control of pests is also featured. A third component is a section on parasitoid venoms, which are of interest to the pharmaceutical and medical communities as well as insect-oriented biologists. Sections focus on both virus evolution and genomics as well as proteomics and functional roles of polydnavirus-encoded gene products International researchers and emerging leaders in their fields provide readers with syntheses of the latest research Includes content on both symbiotic viruses and pathogenic viruses, plus new research on parasitoid venoms Cutting-edge section on future directions in the field covers the impacts of polydnavirus research on medicine, human health, bioengineering and the economy, increasing the value for researchers and practitioners who need to stay on top of the research in this swiftly moving field



Handbook of Biological Control

Handbook of Biological Control Author T. W. Fisher
ISBN-10 0080533019
Release 1999-09-20
Pages 1046
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For many years the use of chemical agents such as pesticides and herbicides has been effective in controlling the many varieties of pests that infest both agricultural crops and backyard gardens. However, these pests are gradually becoming resistant to these agents, because the agents themselves are acting as selective factors making the pests better and better able to resist and persist. As a result, the use of biological controlling agents is increasing. This book is a comprehensive and authoritative handbook of biological control. Key Features * Introduction (preface plus 2 chapters) * Principles and processes (12 chapters) * Agents, biology, and methods (6 chapters) * Applications (10 chapters) * Research (2 chapters)



Plant Viruses

Plant Viruses Author Rajarshi Kumar Gaur
ISBN-10 9781351667746
Release 2018-01-12
Pages 387
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Plant viruses are significant as they affect our food supply and are capable of rapidly spreading to new plant species, so a comprehensive study of plant viruses is important in understanding their pathogenesis and prevention. This book focuses on the plant virus evolution, their molecular classification, epidemics and management. The key features in the book includes genome organization, translation and replication, virus-coded proteinases, structure of virus particles, cell receptors and host range, the RNA polymerase, quasispecies dynamics and virus evolution, and its natural habitats.



Virology

Virology Author John Carter
ISBN-10 9780470023860
Release 2007-08-15
Pages 358
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Virology is a clear and accessible introduction to this fast moving field, providing a comprehensive resource enabling students to understand the key concepts surrounding this exciting subject. The authors have produced a text that stimulates and encourages the student through the extensive use of clear, colour-coded diagrams. Taking a modern approach to the subject, the relevance of virology to everyday life is clearly emphasised and discussion on emerging viruses, cancer, vaccines, anti-viral drugs gene vectors and pesticides is included. This title: Provides an introduction to the theories behind the origins of viruses and how they are evolving with discussion on emerging viruses Includes numerous diagrams with standard colour coding for different types of molecule such as DNA, messenger RNA, other virus RNA’s proteins – all diagrams are carefully developed and clearly labelled to enhance student understanding Features self-contained descriptions of the complete replication cycles of a selection of viruses Introduces the relevance of virology to the modern world including the latest developments in the field - HIV, Foot and Mouth disease, Ebola, SARS and MMR Presents summary boxes, further reading and an associated website to include the latest developments Virology is an essential textbook for all undergraduate students of biology, microbiology and biomedical sciences taking courses in virology. It is also an invaluable resource for MSc level students who have previously done little or no virology and are looking for an accessible introduction to the subject.



Structure and Physics of Viruses

Structure and Physics of Viruses Author Mauricio G. Mateu
ISBN-10 9789400765528
Release 2013-06-04
Pages 728
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This book contemplates the structure, dynamics and physics of virus particles: From the moment they come into existence by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognise and infect a new host cell and cease to exist by losing their physical integrity to start a new infectious cycle. (Bio)physical techniques used to study the structure of virus particles and components, and some applications of structure-based studies of viruses are also contemplated. This book is aimed first at M.Sc. students, Ph.D. students and postdoctoral researchers with a university degree in biology, chemistry, physics or related scientific disciplines who share an interest or are actually working on viruses. We have aimed also at providing an updated account of many important concepts, techniques, studies and applications in structural and physical virology for established scientists working on viruses, irrespective of their physical, chemical or biological background and their field of expertise. We have not attempted to provide a collection of for-experts-only reviews focused mainly on the latest research in specific topics; we have not generally assumed that the reader knows all of the jargon and all but the most recent and advanced results in each topic dealt with in this book. In short, we have attempted to write a book basic enough to be useful to M.Sc and Ph.D. students, as well as advanced and current enough to be useful to senior scientists with an interest in Structural and/or Physical Virology.



RNA Interference and Viruses

RNA Interference and Viruses Author Miguel Angel Martínez
ISBN-10 9781904455561
Release 2010-01-01
Pages 252
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Since its discovery in 1998, RNA interference (RNAi) has heralded the advent of novel tools for biological research and drug discovery. This exciting new technology is emerging as a powerful modality for battling some of the most notoriously challenging viral clinical targets, such as the hepatitis C virus (HCV) and the human immunodeficiency virus (HIV). However, several critical issues associated with this novel technology must be resolved before it can progress to testing in human clinical trials, and these have been the target of intensive research in recent years. In this book, expert RNAi specialists from around the world have teamed up to produce a timely and thought-provoking review of the area. The two central themes are: 1) the latest findings on RNAi-virus interactions and 2) progress in the development of RNAi-based antiviral therapeutics. A number of chapters explain general concepts concerned with the role of RNAi in natural antiviral defense mechanisms. Other chapters discuss how to improve the efficacy and safety of RNAi-based antiviral drugs, as well as describe how this technology is being developed as a new therapeutic tool for fighting specific viruses, including HIV, HCV, and respiratory viruses. The book also outlines potential new avenues for research. RNA Interference and Viruses is essential reading for researchers involved in RNAi or antiviral research and is a recommended text for all virology laboratories.



Of Mice Men and Microbes

Of Mice  Men  and Microbes Author David R. Harper
ISBN-10 0080491987
Release 1999-06-28
Pages 278
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In May 1993, a cluster of cases of a lethal disease among healthy young people brought the attention of the world to the southwestern deserts. A previously unknown disease was killing up to 80% of the people it infected. The reaction in the area and across the nation mixed fear, lack of information, and the struggles of doctors to save the victims of an unknown killer with hard science and the age old rhythmns of the desert. What came out was the story of a virus that had been killing since man arrived in the American continents, Hantavirus, with deadly relatives across the Americas and across the world. This book explains why and how the virus kills, and why it is still killing today. Why all of the science aimed at a virus identified back in 1993 has not brought a vaccine or a cure is part of the story, as is how that killer virus fits into the story of "new" diseases across the world. The story of hantavirus disease, what has happened since that first outbreak, and what the real risks are is laid out by an experienced scientist and an award winning journalist living and working in the area of the 1993 outbreak. Covers the full story of the recent hantavirus outbreak Includes interviews with survivors, and local reaction Presents the science in lay terms Places the event in the broader context of emerging diseases worldwide The only account which takes the reader beyond the initial outbreak in 1993-1994, bringing them up to late 1998 Discusses hantavirus disease in the U.S., Argentina, and Canada



Virus Insect Plant Interactions

Virus Insect Plant Interactions Author Kerry F. Harris
ISBN-10 9780080543598
Release 2001-10-16
Pages 376
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In Virus-Insect-Plant Interactions, the world's leading scientists discuss the latest breakthroughs in understanding the biological and ecological factors that define these complex transmission systems and how this knowledge might be used to our advantage in producing innovative, user and environmentally friendly approaches to controlling the spread of plant pathogens by insects. This is an invaluable reference work for researchers, teachers, and students. There are many quick-reference figures and tables, the contents pages include individual chapter abstracts, and each chapter ends with its own bibliography. Presents the most significant research breakthroughs of the past two decades Contains eighteen chapters by forty-two world-renowned researchers Invaluable reference work for researchers, teachers and students Each chapter ends with its own bibliography Contents pages of forematter include individual chapter abstracts Contains many quick-reference figures and tables