Download or read online books in PDF, EPUB and Mobi Format. Click Download or Read Online button to get book now. This site is like a library, Use search box in the widget to get ebook that you want.

Vitamin D

Vitamin D Author Michael F. Holick
ISBN-10 1603273034
Release 2010-06-27
Pages 1160
Download Link Click Here

In Vitamin D: Physiology, Molecular Biology, and Clinical Applications, Second Edition, leading researchers provide a comprehensive, highly readable overview of the biological functions and clinical applications of vitamin D and its metabolites. Topics range from the most recent recommendations for vitamin D intake to new approaches for the treatment and prevention of vitamin D deficiency and the development of active vitamin D drugs to treat psoriasis and cancer. The book demonstrates the significant role that vitamin D has in maintaining good bone health and the prevention of osteoporosis, an important health problem for adults over the age of fifty. In addition, it authoritatively reviews the relationship between sunlight exposure, vitamin D, and increased risk of colon and breast cancer; how vitamin D is made in the skin; and the sequence of events that leads to its activation by the kidney. Also examined are the biological functions of 1,25-dihydrovitamin D3 on the intestine and bone, as well as other tissues, such as skin, the immune system, prostate, and breast, and vitamin D's molecular mechanism of action on the cell membrane and nucleus. The first edition of Vitamin D: Physiology, Molecular Biology and Clinical Applications was the benchmark in the field when published in 1999. This new and expanded volume continues to include extensive, in-depth chapters covering the most important aspects of the complex interactions between vitamin D and other dietary components, the ongoing debate concerning the best indicator of optimal vitamin D status and its nutrient requirements, and the impact of less than optimal status on disease risk. Vitamin D: Physiology, Molecular Biology, and Clinical Applications, Second Edition is designed and organized not only to be an up-to-date review on the subject, but also to provide medical students, graduate students, health care professionals and even the lay public with a reference source for the most up-to-date information about the vitamin D deficiency pandemic and its clinical implications for health and disease.



Vitamin D

Vitamin D Author David Feldman
ISBN-10 0080543642
Release 2005-01-25
Pages 1952
Download Link Click Here

Vitamin D, a steroid hormone, has mainly been known for its effects on bone and osteoporosis. The current therapeutic practices expand into such markets as cancer research, pediatrics, nephrology, dermatology, immunology, and genetics. This second edition includes over 100 chapters covering everything from chemistry and metabolism to mechanisms of action, diagnosis and management, new analogs, and emerging therapies. This complete reference works is a must have resource for anyone working in endocrinology, osteology, bone biology, or cancer research. *Most comprehensive, up-to-date two-volume set on Vitamin D *New chapters on squamous cell cancer, brain cancer, thyroid cancer and many more *Further sections on emerging uses for treatments of auto-immune diseases and diabetes *Over 600 illustrations and figures available on CD



Vitamin D

Vitamin D Author David Feldman
ISBN-10 9780128099643
Release 2017-12-18
Pages 1266
Download Link Click Here

Vitamin D: Volume 2: Health, Disease and Therapeutics, Fourth Edition, authoritatively covers the evidence for new roles for vitamin D, ranging from cardiovascular disease, to cancer, diabetes, inflammatory bowel disease, multiple sclerosis and renal disease. This collection represents a who’s who of vitamin D research and the coverage is appropriately broad, drawing in internal medicine, orthopedics, oncology and immunology. Clinical researchers will gain a strong understanding of the molecular basis for a particular area of focus. Offers a comprehensive reference, ranging from basic bone biology, to biochemistry, to the clinical diagnostic and management implications of vitamin D Saves researchers and clinicians time in quickly accessing the very latest details on the diverse scientific and clinical aspects of Vitamin D, as opposed to searching through thousands of journal articles Chapter authors include the most prominent and well-published names in the field Targets chemistry, metabolism and circulation, mechanisms of action, mineral and bone homeostasis and vitamin D deficiency Presents a clinical focus on disorders, analogs, cancer, immunity, inflammation, disease and therapeutic applications



Vitamin D

Vitamin D Author David Feldman
ISBN-10 9780128099667
Release 2017-12-18
Pages 1180
Download Link Click Here

Vitamin D: Volume One: Biochemistry, Physiology and Diagnostics, Fourth Edition, presents the latest information from international experts in endocrinology, bone biology and human physiology, taking readers through the basic research of vitamin D. This impressive reference presents a comprehensive review of the multifaceted vitamin D. Researchers from all areas will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted genomic and proteomic insights on the mechanisms of disease. Offers a comprehensive reference, ranging from basic bone biology, to biochemistry, to the clinical diagnostic and management implications of vitamin D Saves researchers and clinicians time in quickly accessing the very latest details on the diverse scientific and clinical aspects of Vitamin D, as opposed to searching through thousands of journal articles Targets chemistry, metabolism and circulation, mechanisms of action, mineral and bone homeostasis, human physiology, diagnosis and management, nutrition, sunlight, genetics and vitamin D deficiency Volume II of this collection presents a clinical focus on disorders, analogs, cancer; immunity, inflammation and disease and therapeutic applications



The Vitamins

The Vitamins Author Gerald F. Combs, Jr.
ISBN-10 9780128029831
Release 2016-12-15
Pages 628
Download Link Click Here

The Vitamins: Fundamental Aspects in Nutrition and Health, Fifth Edition, provides the latest coverage of the biochemistry and physiology of vitamins and vitamin-like substances. Health-related themes present insights into the use of vitamins, not only for general nutritional balance, but also as a factor in the prevention and/or treatment of specific health issues, such as overall immunity, inflammatory diseases, obesity, and anemia. Readers will gain an understanding of the roles vitamins play in gene expression and epigenetics, providing important information on the further development of personalized medical treatments that will also allow them to establish appropriate dietary programs based on individual genetic profiles. This cohesive, well-organized presentation of each vitamin includes key words, case studies, and coverage of the metabolic functions of appropriate vitamins. The readability of this complex content is highly regarded by students, instructors, researchers, and professionals alike. Includes diagnostic trees for vitamin deficiencies to help readers visually understand and recognize signs of specific deficiencies Updated tables and figures throughout serve as quick references and support key takeaways Provides learning aids, such as call-out boxes to increase comprehension and retention of important concepts



Molecular Basis of Nutrition and Aging

Molecular Basis of Nutrition and Aging Author Marco Malavolta
ISBN-10 9780128018279
Release 2016-04-15
Pages 784
Download Link Click Here

Molecular Basis of Nutrition and Aging: A Volume in the Molecular Nutrition Series focuses on the nutritional issues associated with aging and the important metabolic consequences of diet, nutrition, and health. The book is subdivided into four parts that reflect the impact of nutrition from a biomolecular level to individual health. In Part One, chapters explore the general aspects of aging, aging phenotypes, and relevant aspects of nutrition related to the elderly and healthy aging. Part Two includes molecular and cellular targets of nutrition in aging, with chapters exploring lipid peroxidation, inflammaging, anabolic and catabolic signaling, epigenetics, DNA damage and repair, redox homeostasis, and insulin sensitivity, among others. Part Three looks at system-level and organ targets of nutrition in aging, including a variety of tissues, systems, and diseases, such as immune function, the cardiovascular system, the brain and dementia, muscle, bone, lung, and many others. Finally, Part Four focuses on the health effects of specific dietary compounds and dietary interventions in aging, including vitamin D, retinol, curcumin, folate, iron, potassium, calcium, magnesium, zinc, copper, selenium, iodine, vitamin B, fish oil, vitamin E, resveratrol, polyphenols, vegetables, and fruit, as well as the current nutritional recommendations. Offers updated information and a perspectives on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of aging Explores how nutritional factors are involved in the pathogenesis of aging across body systems Investigates the molecular and genetic basis of aging and cellular senescence through the lens of the rapidly evolving field of molecular nutrition



The Plasticity of Skeletal Muscle

The Plasticity of Skeletal Muscle Author Kunihiro Sakuma
ISBN-10 9789811032929
Release 2017-03-01
Pages 292
Download Link Click Here

This book discusses recent advances and various topics in plasticity of skeletal muscle from the perspectives of morphology, biological function, and clinical applications. Skeletal muscle is a highly plastic organ to adapt to environmental various demands, appears to endocrine various myokines, which flow into blood to protect the recognizing function of brain and inhibit the appearance of several cancer tumorigenesis. The book deals with current stem-cell based, pharmacological, and nutritional therapies for muscle wasting (sarcopenia, cachexia, and muscular dystrophy). It also explains the roles of biological mediators such as PGC-1, transient receptor potential cation channels (TRPC), and AMPK in modulating muscle function. The functional roles of ubiquitin-proteasome system, autophagy-dependent signaling in muscle homeostasis, ribosome biogenesis, and redox regulation of mechanotransduction to modulate skeletal muscle mass are also covered. It is an essential resource for physicians, researchers, post-docs as well as graduate students in the field of sports science including rehabilitation therapy, exercise physiology, exercise biochemistry, and molecular biology dealing with skeletal muscle.



Molecular Genetic and Nutritional Aspects of Major and Trace Minerals

Molecular  Genetic  and Nutritional Aspects of Major and Trace Minerals Author James F Collins
ISBN-10 9780128023761
Release 2016-09-14
Pages 576
Download Link Click Here

Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals is a unique reference that provides a complete overview of the non-vitamin micronutrients, including calcium, copper, iodine, iron, magnesium, manganese, molybdenum, phosphorus, potassium, selenium, sodium, and zinc. In addition, the book covers the nutritional and toxicological properties of nonessential minerals chromium, fluoride and boron, and silicon and vanadium, as well as ultra-trace minerals and those with no established dietary requirement for humans. Users will find in-depth chapters on each essential mineral and mineral metabolism, along with discussions of dietary recommendations in the United States and around the world. Presents the only scientific reference to cover all of the nutritionally relevant essential major and trace minerals Provides a broad introductory chapter on each mineral to give readers valuable background and context Clarifies the cellular and molecular aspects of each mineral and its genetic and genomic aspects Includes coverage of all nutritionally relevant minerals—essential major trace minerals and ultra-trace minerals Underscores the important interactions between minerals so readers learn how metabolism of one mineral influences another



Diet and Exercise in Cystic Fibrosis

Diet and Exercise in Cystic Fibrosis Author Ronald Ross Watson
ISBN-10 9780128005880
Release 2014-07-29
Pages 396
Download Link Click Here

Diet and Exercise in Cystic Fibrosis, a unique reference edited by distinguished and internationally recognized nutritionist and immunologist Ronald Ross Watson, fills the gap in the current dietary modalities aimed at controlling cystic fibrosis. Using expert evaluation on the latest studies of the role of food and exercise in lifelong management of cystic fibrosis, this valuable resource shows how to maintain intestinal, hepatic, and pulmonary high quality function for improving quality of life for those with cystic fibrosis. A helpful tool for researchers and clinicians alike, this reference helps refine research targets, and provides the beginning of a structured dietary management scheme for those with cystic fibrosis. Provides a detailed resource that reviews the health problems occurring in Cystic Fibrosis relative to dietary, complementary, and alternative therapies Contains expert evaluation on the role of foods and exercise for lifelong management of Cystic Fibrosis to maintain intestinal, hepatic, and pulmonary high quality function for improved quality of life Defines and evaluates various nutritional and dietary approaches to the unique problems of those with Cystic Fibrosis



Handbook of Vitamins Fifth Edition

Handbook of Vitamins  Fifth Edition Author Janos Zempleni
ISBN-10 9781466515574
Release 2013-07-29
Pages 605
Download Link Click Here

Within the last few years, knowledge about vitamins has increased dramatically, resulting in improved understanding of human requirements for many vitamins. This new edition of a bestseller presents comprehensive summaries that analyze the chemical, physiological, and nutritional relationships, as well as highlight newly identified functions, for all recognized vitamins. These include vitamins A, D, K, E, B6, B12, niacin, riboflavin, thiamine, pantothenic acid, biotin, folate, choline, and ascorbic acid. Keeping the tradition of the previous volumes, the Handbook of Vitamins, Fifth Edition provides an updated, contemporary perspective on vitamins in human nutrition. Bringing together leading experts in molecular biology, biochemistry, and physiology, the book contains substantial revisions in every chapter, covering vitamin metabolism, including human requirements, clinical aspects of deficiency, vitamin-dependant cell signals and gene regulation, and roles as coenzymes. The chapter on epigenetics has been updated and expanded to include novel findings about vitamins not previously considered in studies of nutrient-dependent epigenome modification. The book also contains a new chapter on genome stability, highlighting current understanding of vitamin–genome interactions in the evolution of the human genome and the functional consequences of human genetic variation. Maintaining its status as a high-quality reference, this handbook incorporates new discoveries into an updated and revised fifth edition.



Handbook of Nutrition Diet and the Eye

Handbook of Nutrition  Diet and the Eye Author Victor R. Preedy
ISBN-10 9780124046061
Release 2014-04-01
Pages 704
Download Link Click Here

The Handbook of Nutrition, Diet and the Eye is the first book to thoroughly address common features and etiological factors in how dietary and nutritional factors affect the eye. The ocular system is perhaps one of the least studied organs in diet and nutrition, yet the consequences of vision loss can be devastating. One of the biggest contributors to complete vision loss in the western hemisphere is diabetes, precipitated by metabolic syndrome. In some developing countries, micronutrient deficiencies are major contributory factors to impaired vision. However, there are a range of ocular defects that have either their origin in nutritional deficiencies or excess or have been shown to respond favorably to nutritional components. The eye from the cornea to the retina may be affected by nutritional components. Effects may be physiological or molecular. This book represents essential reading for nutritionists, dietitians, optometrists, ophthalmologists, opticians, endocrinologists, and other clinicians and researchers interested in eye health and vision in general. Saves clinicians and researchers time in quickly accessing the very latest details on a broad range of nutrition, ocular health, and disease issues Provides a common language for nutritionists, nutrition researchers, optometrists, and ophthalmologists to discuss how dietary and nutritional factors, and related diseases and syndromes affect the eye Preclinical, clinical, and population studies will help nutritionists, dieticians, and clinicians map out key areas for research and further clinical recommendations



Biochemistry And Physiology of Nutrition

Biochemistry And Physiology of Nutrition Author Geoffrey Bourne
ISBN-10 9780323143882
Release 2012-12-02
Pages 654
Download Link Click Here

Biochemistry and Physiology of Nutrition, Volume II focuses on the processes, methods, and studies on nutrition. The book starts by discussing intracellular localization through histochemical methods of enzymes and vitamins; the structural changes in vitamin deficiency; and microbiology of digestion. Deficiencies in vitamins, A, C, D, E, B1, riboflavin, nicotinic acid, choline, biotin, and folic acid are noted. The book then focuses on microbiology of digestion, considering the establishment of microbial population in the alimentary tract, results of microbial digestion, antibiotics, and intestinal flora of man. The text also defines the nutrition system of worms, insects, and protozoa. The generation of ATP in terminal respiration and anaerobic glycolysis, as well as ATP's role in energy transfer, is noted. The discussions also focus on hydrolytic and phosphorylitic enzymes, such as carbohydrates, esterases, amidases, phosphatases, and phosporylases. Other topics covered are respiratory enzymes and coenzymes in which nucleotides, glucose diphosphate, diphosphoglyceric acid, and thiamine pyrophosphate are noted. The book notes the functions of iron compounds in the body, particularly in blood and tissues, and then touches on calcium and phosphorus metabolism. Given considerations are calcium and phosphorus in blood, skeletal calcium and phosphorus, and the factors affecting adsorption. A discussion also focuses on trace elements and the effects of protein, carbohydrates, fats, and vitamins in nutrition. The book is a vital source of data for readers interested in studying the elements, factors, processes, and methods involved in nutrition.



Molecular Pathology

Molecular Pathology Author William B. Coleman
ISBN-10 9780128027875
Release 2017-11-09
Pages 802
Download Link Click Here

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase



Physiology of the Heart

Physiology of the Heart Author Arnold M. Katz
ISBN-10 9781608311712
Release 2010-11-09
Pages 576
Download Link Click Here

Dr. Arnold Katz's internationally acclaimed classic, Physiology of the Heart, is now in its thoroughly revised Fifth Edition, incorporating the latest molecular biology research and extensively exploring the clinical applications of these findings. In the single authored, expert voice that is this book's unique strength, Dr. Katz provides a comprehensive overview of the physiological and biophysical basis of cardiac function, beginning with structure and proceeding to biochemistry, biophysics, and pathophysiology in arrhythmias, ischemia, and heart failure. Emphasis is on the interrelationships of basic processes among the cell, cardiac muscle function, and the biophysics of contractile and electrical behavior. This edition includes new material on cell signaling and molecular biology.



Molecular Nutrition and Diabetes

Molecular Nutrition and Diabetes Author Didac Mauricio
ISBN-10 9780128017616
Release 2015-12-08
Pages 400
Download Link Click Here

Molecular Nutrition and Diabetes: A Volume in the Molecular Nutrition Series focuses on diabetes as a nutritional problem and its important metabolic consequences. Fuel metabolism and dietary supply all influence the outcome of diabetes, but understanding the pathogenesis of the diabetic process is a prelude to better nutritional control. Part One of the book provides general coverage of nutrition and diabetes in terms of dietary patterns, insulin resistance, and the glucose-insulin axis, while Part Two presents the molecular biology of diabetes and focuses on areas such as oxidative stress, mitochondrial function, insulin resistance, high-fat diets, nutriceuticals, and lipid accumulation. Final sections explore the genetic machinery behind diabetes and diabetic metabolism, including signaling pathways, gene expression, genome-wide association studies, and specific gene expression. While the main focus of each chapter is the basic and clinical research on diabetes as a nutritional problem, all chapters also end with a translational section on the implications for the nutritional control of diabetes. Offers updated information and a perspective on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of diabetes mellitus Explores how nutritional factors are involved in the pathogenesis of both type1 and type2 diabetes and their complications Investigates the molecular and genetic bases of diabetes and diabetic metabolism through the lens of a rapidly evolving field of molecular nutrition



Hormones

Hormones Author Anthony W. Norman
ISBN-10 9780080919065
Release 2014-07-30
Pages 430
Download Link Click Here

The 3rd edition of Hormones offers a comprehensive treatment of the hormones of humans all viewed from the context of current theories of their action in the framework of our current understanding their physiological actions as well as their molecular structures, and those of their receptors. This new edition of Hormones is intended to be used by advanced undergraduates and graduate students in the biological sciences. It will also provide useful background information for first year medical students as they engage in studies which are increasingly problem-based rather than discipline-focused. As the field of endocrinology itself has expanded so much in the past two decades, the up to date presentation of the basics presented in this book will be a solid foundation on which more specialized considerations can be based. New to this Edition: Hormones, 3rd Edition is organized with two introductory chapters followed by 15 chapters on selected topics of the molecular biology of the major endocrine systems operative in humans. Coverage, for the first time of the following hormones; ghrelin, oxyntomodulin, kisspeptin, adrenomedullin, FGF23, erythropoietin, VIP and extended coverage of NO. Coverage of the hypothalamus has been integrated with the anterior pituitary because of the intimate functional and relationship between the two. Consideration of the role of hormones in cancer has been integrated into the chapters on the relevant hormones. Each of these areas occupies a unique niche in our understanding of the biological world and is part of the universality of signaling systems and how they govern biological systems. Organized with two introductory chapters, followed by 15 chapters on selected topics of the molecular biology of the major human endocrine systems New full color format includes over 300 full color, completely redrawn images Companion web site will host all images from the book as PPT slides and .jpeg files All chapters have been completely updated and revitalized. Coverage of the hypothalamus has been integrated into the anterior pituitary chapter and coverage of the thymus has been eliminated and left to immunology textbooks Provides essential basics for advanced undergraduates and graduate students in the biological sciences, as well as first year medical students as they engage in studies which are increasingly problem-based rather than discipline-focused



Calcium Regulating Hormones Vitamin D Metabolites and Cyclic AMP Assays and Their Clinical Application

Calcium Regulating Hormones  Vitamin D Metabolites  and Cyclic AMP Assays and Their Clinical Application Author Heinrich Schmidt-Gayk
ISBN-10 9783662004067
Release 2012-12-06
Pages 370
Download Link Click Here

Calcium Regulating Hormones Vitamin D Metabolites and Cyclic AMP Assays and Their Clinical Application has been writing in one form or another for most of life. You can find so many inspiration from Calcium Regulating Hormones Vitamin D Metabolites and Cyclic AMP Assays and Their Clinical Application also informative, and entertaining. Click DOWNLOAD or Read Online button to get full Calcium Regulating Hormones Vitamin D Metabolites and Cyclic AMP Assays and Their Clinical Application book for free.